ATE388705T1 - Fentanyl zusammensetzung zur nasalen anwendung - Google Patents
Fentanyl zusammensetzung zur nasalen anwendungInfo
- Publication number
- ATE388705T1 ATE388705T1 AT01960190T AT01960190T ATE388705T1 AT E388705 T1 ATE388705 T1 AT E388705T1 AT 01960190 T AT01960190 T AT 01960190T AT 01960190 T AT01960190 T AT 01960190T AT E388705 T1 ATE388705 T1 AT E388705T1
- Authority
- AT
- Austria
- Prior art keywords
- fentanyl
- administration
- nasal
- results
- action
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200001154 | 2000-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE388705T1 true ATE388705T1 (de) | 2008-03-15 |
Family
ID=8159630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01960190T ATE388705T1 (de) | 2000-07-31 | 2001-07-31 | Fentanyl zusammensetzung zur nasalen anwendung |
Country Status (24)
Country | Link |
---|---|
US (3) | US8017627B2 (de) |
EP (3) | EP1307194B2 (de) |
JP (2) | JP4898073B2 (de) |
KR (2) | KR100888275B1 (de) |
CN (2) | CN101181241A (de) |
AT (1) | ATE388705T1 (de) |
AU (2) | AU2001281746C1 (de) |
CA (1) | CA2417727C (de) |
CY (2) | CY1107405T1 (de) |
DE (2) | DE60133203T3 (de) |
DK (2) | DK1307194T4 (de) |
EA (1) | EA006384B1 (de) |
EE (1) | EE05420B1 (de) |
ES (2) | ES2427976T5 (de) |
HK (1) | HK1089106A1 (de) |
IL (2) | IL154041A0 (de) |
IS (1) | IS2803B (de) |
NO (2) | NO330565B1 (de) |
NZ (1) | NZ524396A (de) |
PL (1) | PL207845B1 (de) |
PT (2) | PT1307194E (de) |
SI (2) | SI1307194T2 (de) |
UA (2) | UA77398C2 (de) |
WO (1) | WO2002009707A1 (de) |
Families Citing this family (43)
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US20040115133A1 (en) * | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
DK1307194T4 (da) | 2000-07-31 | 2011-07-18 | Nycomed Danmark Aps | Fentanylpræparat til nasal administration |
US20020106407A1 (en) * | 2000-12-11 | 2002-08-08 | Dennis Coleman | Method and apparatus for treating breakthrough pain |
US20090281023A9 (en) * | 2001-06-04 | 2009-11-12 | Nobex Corporation | Mixtures Of Calcitonin Drug-Oligomer Conjugates And Methods Of Use In Pain Treatment |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
GB0210264D0 (en) * | 2002-05-03 | 2002-06-12 | Arakis Ltd | The treatment of pain and migraine headache |
GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
GB0305579D0 (en) * | 2003-03-11 | 2003-04-16 | Dallas Burston Ltd | Pharmaceutical compositions |
GB0315632D0 (en) | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
US20070053965A1 (en) * | 2005-02-25 | 2007-03-08 | Gruenenthal Gmbh | Kit comprising a plaster, optionally containing an active substance, and an agent that at least partially reduces skin irritation |
US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US9289583B2 (en) | 2006-01-06 | 2016-03-22 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8252328B2 (en) * | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US9066847B2 (en) | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
US8202535B2 (en) * | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
CN104138634B (zh) * | 2006-04-13 | 2016-09-07 | 梯瓦制药国际有限责任公司 | 递送抗偏头痛化合物的透皮方法和系统 |
US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
US10512644B2 (en) | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
WO2009070829A1 (en) * | 2007-12-05 | 2009-06-11 | Krius Pty Ltd | Non-aqueous oil-based fentanyl compositions for transmucosal administration |
ES2648196T3 (es) | 2008-02-07 | 2017-12-29 | The University Of Washington | Dispositivo aerosol circunferencial |
GB2464282A (en) * | 2008-10-08 | 2010-04-14 | Archimedes Dev Ltd | A device for administering a dose of opioid analgesic |
US8945592B2 (en) | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
DE102009001041A1 (de) * | 2009-02-20 | 2010-08-26 | Marien-Apotheke Fulda Ohg | Notfallset zur Herstellung eines Arzneimittels zur nasalen Anwendung von Opioiden bei Atemnot |
WO2012024595A2 (en) | 2010-08-20 | 2012-02-23 | University Of Washington | Circumferential aerosol device for delivering drugs to olfactory epithelium and brain |
PL2670674T3 (pl) | 2011-02-04 | 2017-02-28 | Archimedes Development Limited | Ulepszony pojemnik |
BR112013022249B8 (pt) | 2011-03-03 | 2022-10-25 | Impel Neuropharma Inc | Dispositivo de distribuição de droga nasal |
CN103619485B (zh) | 2011-05-09 | 2017-08-08 | 英倍尔药业股份有限公司 | 用于鼻腔药物递送的喷嘴 |
SG194927A1 (en) * | 2011-05-13 | 2013-12-30 | Euro Celtique Sa | Intranasal pharmaceutical dosage forms comprising naloxone |
WO2014179228A1 (en) | 2013-04-28 | 2014-11-06 | Impel Neuropharma Inc. | Medical unit dose container |
MX2017008428A (es) | 2014-12-23 | 2018-03-23 | Acelrx Pharmaceuticals Inc | Sistemas, dispositivos y métodos para dispensar formas de dosificación transmucosa oral. |
JP6753927B2 (ja) | 2015-09-10 | 2020-09-09 | インペル ニューロファーマ インコーポレイテッド | 直列形経鼻送達デバイス |
WO2019104205A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with dip tube |
WO2019104192A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with inlet interface |
JP2021509677A (ja) | 2018-01-05 | 2021-04-01 | インペル ニューロファーマ インコーポレイテッド | 精密嗅覚装置によるオランザピンの鼻孔間送達 |
AU2019205318B2 (en) | 2018-01-05 | 2022-02-03 | Impel Pharmaceuticals Inc. | Intranasal delivery of dihydroergotamine by precision olfactory device |
CN112955134A (zh) | 2018-07-19 | 2021-06-11 | 英倍尔药业股份有限公司 | 用于治疗帕金森氏病的左旋多巴和多巴脱羧酶抑制剂的呼吸道递送 |
KR20210109007A (ko) | 2019-01-03 | 2021-09-03 | 임펠 뉴로파마 인코포레이티드 | 비강 약물 전달 장치 |
EP3969085A4 (de) | 2019-05-17 | 2023-06-21 | Impel Pharmaceuticals Inc. | Einwegvorrichtung zur nasalen verabreichung |
WO2022038403A1 (ru) | 2020-10-15 | 2022-02-24 | Владимир ТИМКО | Фармацевтическая композиция на основе налбуфина и/или его солей для назального применения |
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-
2001
- 2001-07-31 DK DK01960190.5T patent/DK1307194T4/da active
- 2001-07-31 AU AU2001281746A patent/AU2001281746C1/en active Active
- 2001-07-31 SI SI200130827T patent/SI1307194T2/sl unknown
- 2001-07-31 WO PCT/DK2001/000521 patent/WO2002009707A1/en active IP Right Grant
- 2001-07-31 EE EEP200300050A patent/EE05420B1/xx unknown
- 2001-07-31 CN CNA2007101539372A patent/CN101181241A/zh active Pending
- 2001-07-31 DE DE60133203T patent/DE60133203T3/de not_active Expired - Lifetime
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