ATE353902T1 - Optisch reine camptothecin-analoge - Google Patents

Optisch reine camptothecin-analoge

Info

Publication number
ATE353902T1
ATE353902T1 AT03075924T AT03075924T ATE353902T1 AT E353902 T1 ATE353902 T1 AT E353902T1 AT 03075924 T AT03075924 T AT 03075924T AT 03075924 T AT03075924 T AT 03075924T AT E353902 T1 ATE353902 T1 AT E353902T1
Authority
AT
Austria
Prior art keywords
optically pure
camptothecin analogues
pure camptothecin
analogues
optically
Prior art date
Application number
AT03075924T
Other languages
German (de)
English (en)
Inventor
Olivier Lavergne
Dennis Bigg
Christophe Lanco
Alain Rolland
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE353902T1 publication Critical patent/ATE353902T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT03075924T 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge ATE353902T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9902398A FR2790261B1 (fr) 1999-02-26 1999-02-26 Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation

Publications (1)

Publication Number Publication Date
ATE353902T1 true ATE353902T1 (de) 2007-03-15

Family

ID=9542564

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00907714T ATE242248T1 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine
AT03075924T ATE353902T1 (de) 1999-02-26 2000-02-24 Optisch reine camptothecin-analoge

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT00907714T ATE242248T1 (de) 1999-02-26 2000-02-24 Optisch reine analoge der camptothecine

Country Status (29)

Country Link
US (1) US7012079B1 (da)
EP (2) EP1338599B1 (da)
JP (1) JP2002537399A (da)
KR (1) KR20010108270A (da)
CN (1) CN1195757C (da)
AR (1) AR022740A1 (da)
AT (2) ATE242248T1 (da)
AU (1) AU772632B2 (da)
BR (1) BR0008526A (da)
CA (1) CA2364705C (da)
CZ (1) CZ20013091A3 (da)
DE (2) DE60003170T2 (da)
DK (1) DK1165565T3 (da)
ES (2) ES2200829T3 (da)
FR (1) FR2790261B1 (da)
HK (1) HK1045514B (da)
HR (1) HRP20010622A2 (da)
HU (1) HUP0200529A3 (da)
IL (2) IL144987A0 (da)
MX (1) MXPA01008658A (da)
MY (1) MY127819A (da)
NO (1) NO327260B1 (da)
NZ (1) NZ514153A (da)
PL (1) PL202393B1 (da)
PT (1) PT1165565E (da)
RU (1) RU2230745C2 (da)
TW (1) TWI268931B (da)
WO (1) WO2000050427A1 (da)
ZA (1) ZA200107738B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
WO2006033011A1 (en) * 2004-09-21 2006-03-30 Societe De Conseils De Recherches Et D'applications Scientifique (S.C.R.A.S.) Novel processes for the production of useful intermediates
US8575484B1 (en) 2010-09-14 2013-11-05 Cooper Technologies Company Adjustable-depth ring assembly and method of installation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768431B1 (fr) 1997-08-29 2000-03-24 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
FR2757514B1 (fr) 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
RO117918B1 (ro) * 1995-06-21 2002-09-30 Sod Conseils Rech Applic Compusi analogi camptotecinei, procedeu de preparare, intermediar, compozitie farmaceutica si utilizare
GB9512670D0 (en) * 1995-06-21 1995-08-23 Sod Conseils Rech Applic Camptothecin analogues
FR2757515B1 (fr) * 1996-12-20 2000-05-05 Sod Conseils Rech Applic Formes prodrogues et nouveaux analogues de la camptothecine, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
BR9711319B1 (pt) * 1996-08-19 2009-08-11 derivados de camptotecina altamente lipofìlicos.
UA57757C2 (uk) * 1996-12-20 2003-07-15 Сос'Єте Де Консей Де Решерш Е Даплікасьон С'Єнтіфік (С.К.Р.А.С.) Аналоги камптотецину, спосіб їх отримання (варіанти) і фармацевтична композиція
CA2280905C (en) * 1997-02-14 2006-08-29 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
US6207673B1 (en) * 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6207832B1 (en) * 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof

Also Published As

Publication number Publication date
IL144987A (en) 2006-12-31
MY127819A (en) 2006-12-29
AU772632B2 (en) 2004-05-06
BR0008526A (pt) 2002-01-08
DE60033447T2 (de) 2007-10-31
NO327260B1 (no) 2009-05-25
CN1345321A (zh) 2002-04-17
HUP0200529A3 (en) 2004-03-29
HRP20010622A2 (en) 2002-08-31
HUP0200529A2 (en) 2002-06-29
US7012079B1 (en) 2006-03-14
ZA200107738B (en) 2003-02-26
EP1165565B1 (fr) 2003-06-04
PT1165565E (pt) 2003-10-31
HK1045514B (zh) 2005-11-18
FR2790261B1 (fr) 2004-09-10
AU2921000A (en) 2000-09-14
WO2000050427A1 (fr) 2000-08-31
NZ514153A (en) 2001-09-28
ATE242248T1 (de) 2003-06-15
JP2002537399A (ja) 2002-11-05
DE60033447D1 (de) 2007-03-29
CA2364705C (fr) 2010-03-30
AR022740A1 (es) 2002-09-04
DK1165565T3 (da) 2003-10-06
IL144987A0 (en) 2002-06-30
CN1195757C (zh) 2005-04-06
CZ20013091A3 (cs) 2002-05-15
KR20010108270A (ko) 2001-12-07
EP1338599A1 (fr) 2003-08-27
HK1045514A1 (en) 2002-11-29
RU2230745C2 (ru) 2004-06-20
NO20014117D0 (no) 2001-08-24
PL202393B1 (pl) 2009-06-30
DE60003170D1 (en) 2003-07-10
TWI268931B (en) 2006-12-21
ES2200829T3 (es) 2004-03-16
EP1338599B1 (fr) 2007-02-14
PL361334A1 (en) 2004-10-04
FR2790261A1 (fr) 2000-09-01
EP1165565A1 (fr) 2002-01-02
DE60003170T2 (de) 2004-04-01
CA2364705A1 (fr) 2000-08-31
NO20014117L (no) 2001-10-11
MXPA01008658A (es) 2002-03-14
ES2282564T3 (es) 2007-10-16

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties