ATE348613T1 - Zolpidem hemitartrat solvat - Google Patents

Zolpidem hemitartrat solvat

Info

Publication number
ATE348613T1
ATE348613T1 AT05001922T AT05001922T ATE348613T1 AT E348613 T1 ATE348613 T1 AT E348613T1 AT 05001922 T AT05001922 T AT 05001922T AT 05001922 T AT05001922 T AT 05001922T AT E348613 T1 ATE348613 T1 AT E348613T1
Authority
AT
Austria
Prior art keywords
solvat
zolpidem hemitartrate
hemitartrate
zolpidem
polymorphs
Prior art date
Application number
AT05001922T
Other languages
English (en)
Inventor
Judith Aronhime
David Leonov
Erzebet Meszaros-Sos
Szaboles Salyi
Csaba Szabo
Shlomo Zavurov
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27394001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE348613(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE348613T1 publication Critical patent/ATE348613T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Amplifiers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05001922T 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat ATE348613T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19929800P 2000-04-24 2000-04-24
US20602500P 2000-05-22 2000-05-22
US22536400P 2000-08-14 2000-08-14

Publications (1)

Publication Number Publication Date
ATE348613T1 true ATE348613T1 (de) 2007-01-15

Family

ID=27394001

Family Applications (4)

Application Number Title Priority Date Filing Date
AT04010651T ATE338550T1 (de) 2000-04-24 2001-04-24 Mikronisierter zolpidem hemitartrat
AT01930705T ATE308324T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat
AT05001922T ATE348613T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat
AT04010435T ATE335481T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT04010651T ATE338550T1 (de) 2000-04-24 2001-04-24 Mikronisierter zolpidem hemitartrat
AT01930705T ATE308324T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04010435T ATE335481T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat

Country Status (21)

Country Link
US (8) US20020077332A1 (de)
EP (1) EP1292304B1 (de)
JP (3) JP2003531173A (de)
KR (1) KR20030069796A (de)
AT (4) ATE338550T1 (de)
AU (2) AU2001257213B2 (de)
CA (1) CA2406982A1 (de)
CZ (1) CZ20023775A3 (de)
DE (7) DE20122435U1 (de)
DK (1) DK1292304T3 (de)
ES (4) ES2239558T3 (de)
HR (1) HRP20020909A2 (de)
HU (1) HUP0300701A2 (de)
IL (1) IL152411A0 (de)
NZ (1) NZ522015A (de)
PL (1) PL358548A1 (de)
PT (3) PT1473036E (de)
SE (1) SE5292304T3 (de)
SK (1) SK16372002A3 (de)
WO (1) WO2001080857A1 (de)
YU (1) YU79402A (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001284322A1 (en) 2000-08-29 2002-03-13 Ranbaxy Laboratories Limited Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem
US6869970B2 (en) 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
DK1575952T3 (da) 2002-12-18 2009-05-25 Mallinckrodt Inc Syntese af heteroarylacetamider
WO2004087703A1 (en) * 2003-03-12 2004-10-14 Sun Pharmaceutical Industries Limited Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
WO2005010002A1 (en) * 2003-07-31 2005-02-03 Ranbaxy Laboratories Limited Process for the synthesis of zolpidem
US7658945B2 (en) * 2004-02-17 2010-02-09 Transcept Pharmaceuticals, Inc. Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
NZ563979A (en) * 2005-05-25 2011-02-25 Transcept Pharmaceuticals Inc Solid compositions and methods for treating middle-of-the night insomnia
CA2617975A1 (en) * 2005-08-19 2007-03-01 Aventis Pharmaceuticals Inc. Combination of a hypnotic agent and r(+)-alpha-(2,3-dimethoxy-phenyl)-1-[2-(4-fluorophenl)ethyl]-4-piperidinemethanol and therapeutic application thereof
ES2336142T3 (es) * 2005-08-19 2010-04-08 Aventis Pharmaceuticals Inc. Combinacion de un agente hipnotico y un compuesto sustituido, con bis arilo y heteroarilo y aplicacion terapeutica del mismo.
AU2006297475A1 (en) * 2005-10-03 2007-04-12 Mallinckrodt Inc. Process for preparing zolpidem hemitartrate and tartrate polymorphs
AU2006303000A1 (en) * 2005-10-17 2007-04-26 Mallinckrodt Inc. Polymorph transformation of Zolpidem in tablet matrix
US20070098788A1 (en) * 2005-10-28 2007-05-03 Gore Subhash P Non-benzodiazepine hypnotic compositions
ES2348829T3 (es) 2006-03-31 2010-12-15 Janssen Pharmaceutica Nv Benzimidazol-2-il-pirimidinas y pirazinas moduladoras del receptor h4 de histamina.
US20080132535A1 (en) * 2006-11-30 2008-06-05 Transcept Pharmaceuticals, Inc. Stabilized Zolpidem Pharmaceutical Compositions
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
TW201018668A (en) * 2008-06-30 2010-05-16 Janssen Pharmaceutica Nv Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
CA2781676C (en) 2009-11-27 2020-05-05 Genzyme Corporation An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
WO2011115069A1 (ja) * 2010-03-19 2011-09-22 第一三共株式会社 結晶の網羅的探索
BR112015021463A8 (pt) 2013-03-06 2019-11-19 Janssen Pharmaceutica Nv moduladores de benzoimidazol-2-il pirimidina do receptor histamínico h4,seu uso e composição faramacêutica

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
FR2408345A1 (fr) * 1976-11-30 1979-06-08 Besins Jean Louis Nouvelle composition a action anti-conceptionnelle
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
DE3018940A1 (de) * 1980-05-17 1981-11-26 Hoechst Ag, 6000 Frankfurt Verwendung eines vinylchlorid-pfropf-copolymerisates in der plastisolverarbeitung
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
US4675323A (en) * 1985-08-06 1987-06-23 Synthelabo Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
SE457326B (sv) * 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
DE3865073D1 (de) * 1987-03-27 1991-10-31 Synthelabo Imidazopyridinderivate, ihre herstellung und therapeutische verwendung.
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
ES2195510T3 (es) * 1999-03-25 2003-12-01 Synthon Bv Derivados de imidazopiridina y procedimiento para prepararlos.
ES2240074T3 (es) * 1999-03-25 2005-10-16 Synthon B.V. Sales de zolpidem.
AU6474200A (en) * 1999-12-13 2001-06-18 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a pyridinemethanol compound

Also Published As

Publication number Publication date
JP2006137778A (ja) 2006-06-01
PT1473036E (pt) 2006-10-31
KR20030069796A (ko) 2003-08-27
SK16372002A3 (sk) 2003-04-01
JP2006249105A (ja) 2006-09-21
US20040220212A1 (en) 2004-11-04
CA2406982A1 (en) 2001-11-01
IL152411A0 (en) 2003-05-29
PT1475093E (pt) 2006-11-30
US20040214859A1 (en) 2004-10-28
DE60122944T2 (de) 2007-04-12
DE60122216D1 (de) 2006-09-21
EP1292304A4 (de) 2003-07-23
ES2238941T1 (es) 2005-09-16
ATE308324T1 (de) 2005-11-15
EP1292304A1 (de) 2003-03-19
DE60114617D1 (de) 2005-12-08
DE60125429D1 (de) 2007-02-01
ES2277301T3 (es) 2007-07-01
CZ20023775A3 (cs) 2003-10-15
US20070037843A1 (en) 2007-02-15
DE60125429T2 (de) 2007-09-27
DE04010435T1 (de) 2005-09-01
PL358548A1 (en) 2004-08-09
ES2238941T3 (es) 2007-04-01
PT1541146E (pt) 2007-01-31
DK1292304T3 (da) 2005-12-19
DE20122435U1 (de) 2005-10-06
US20040220211A1 (en) 2004-11-04
US20020077332A1 (en) 2002-06-20
US20040220210A1 (en) 2004-11-04
DE60114617T2 (de) 2006-07-27
ES2239558T1 (es) 2005-10-01
WO2001080857A1 (en) 2001-11-01
NZ522015A (en) 2004-08-27
HUP0300701A2 (hu) 2003-07-28
DE60122216T2 (de) 2007-08-30
US20040220213A1 (en) 2004-11-04
YU79402A (sh) 2006-03-03
ES2248321T3 (es) 2006-03-16
EP1292304B1 (de) 2005-11-02
ATE335481T1 (de) 2006-09-15
ES2239558T3 (es) 2007-04-01
DE04010651T1 (de) 2005-09-01
DE60122944D1 (de) 2006-10-19
US20040214858A1 (en) 2004-10-28
SE5292304T3 (de) 2005-11-02
HRP20020909A2 (en) 2004-08-31
AU2001257213B2 (en) 2005-09-29
ATE338550T1 (de) 2006-09-15
WO2001080857A9 (en) 2002-06-27
AU5721301A (en) 2001-11-07
JP2003531173A (ja) 2003-10-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties