PT1473036E - Solvato de hemitartarato de zolpidem - Google Patents

Solvato de hemitartarato de zolpidem

Info

Publication number
PT1473036E
PT1473036E PT04010435T PT04010435T PT1473036E PT 1473036 E PT1473036 E PT 1473036E PT 04010435 T PT04010435 T PT 04010435T PT 04010435 T PT04010435 T PT 04010435T PT 1473036 E PT1473036 E PT 1473036E
Authority
PT
Portugal
Prior art keywords
zolpidem
hemitartarato
solvato
polymorphs
preparation
Prior art date
Application number
PT04010435T
Other languages
English (en)
Inventor
Aronhime Judith
Leonov David
Meszaros-Sos Erzebet
Salyi Szaboles
Szabo Csaba
Zavurov Shlomo
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27394001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1473036(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of PT1473036E publication Critical patent/PT1473036E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Amplifiers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT04010435T 2000-04-24 2001-04-24 Solvato de hemitartarato de zolpidem PT1473036E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19929800P 2000-04-24 2000-04-24
US20602500P 2000-05-22 2000-05-22
US22536400P 2000-08-14 2000-08-14

Publications (1)

Publication Number Publication Date
PT1473036E true PT1473036E (pt) 2006-10-31

Family

ID=27394001

Family Applications (3)

Application Number Title Priority Date Filing Date
PT04010435T PT1473036E (pt) 2000-04-24 2001-04-24 Solvato de hemitartarato de zolpidem
PT04010651T PT1475093E (pt) 2000-04-24 2001-04-24 Hemitartarato de zolpidem micronizado
PT05001922T PT1541146E (pt) 2000-04-24 2001-04-24 Solvato de hemitartarato de zolpidem

Family Applications After (2)

Application Number Title Priority Date Filing Date
PT04010651T PT1475093E (pt) 2000-04-24 2001-04-24 Hemitartarato de zolpidem micronizado
PT05001922T PT1541146E (pt) 2000-04-24 2001-04-24 Solvato de hemitartarato de zolpidem

Country Status (21)

Country Link
US (8) US20020077332A1 (pt)
EP (1) EP1292304B1 (pt)
JP (3) JP2003531173A (pt)
KR (1) KR20030069796A (pt)
AT (4) ATE348613T1 (pt)
AU (2) AU5721301A (pt)
CA (1) CA2406982A1 (pt)
CZ (1) CZ20023775A3 (pt)
DE (7) DE20122435U1 (pt)
DK (1) DK1292304T3 (pt)
ES (4) ES2248321T3 (pt)
HR (1) HRP20020909A2 (pt)
HU (1) HUP0300701A2 (pt)
IL (1) IL152411A0 (pt)
NZ (1) NZ522015A (pt)
PL (1) PL358548A1 (pt)
PT (3) PT1473036E (pt)
SE (1) SE5292304T3 (pt)
SK (1) SK16372002A3 (pt)
WO (1) WO2001080857A1 (pt)
YU (1) YU79402A (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6921839B2 (en) 2000-08-29 2005-07-26 Ranbaxy Laboratories Limited Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem
US6869970B2 (en) 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
EP1575952B1 (en) 2002-12-18 2009-02-18 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
WO2004087703A1 (en) * 2003-03-12 2004-10-14 Sun Pharmaceutical Industries Limited Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
EP1660496A1 (en) * 2003-07-31 2006-05-31 Ranbaxy Laboratories Limited Process for the synthesis of zolpidem
KR20130116378A (ko) * 2004-02-17 2013-10-23 트랜스셉트 파마슈티칼스, 인코포레이티드 구강 점막을 가로지르는 수면제 전달용 조성물 및 이의 사용 방법
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
JP2008542299A (ja) * 2005-05-25 2008-11-27 トランセプト・ファーマシューティカルズ・インコーポレイテッド 真夜中不眠症の治療のための固体組成物およびその治療方法
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
CA2617980A1 (en) * 2005-08-19 2007-03-01 Aventis Pharmaceuticals Inc. Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof
WO2007024599A2 (en) * 2005-08-19 2007-03-01 Aventis Pharmaceuticals Inc. Comination of a hypnotic agent and r(+)-alpha-(2,3-dimethoxy-phenyl)-1-[2-(4-fluorophenl)ethyl]-4-piperidinemethanol and therapeutic application thereof
CA2624340A1 (en) * 2005-10-03 2007-04-12 Mallinckrodt Inc. Process for preparing zolpidem hemitartrate and tartrate polymorphs
JP2009511627A (ja) * 2005-10-17 2009-03-19 マリンクロッド・インコーポレイテッド 錠剤マトリックスにおけるゾルピデムの多形転移
US20070098788A1 (en) * 2005-10-28 2007-05-03 Gore Subhash P Non-benzodiazepine hypnotic compositions
SI2007752T1 (sl) 2006-03-31 2010-12-31 Janssen Pharmaceutica Nv Benzoimidazol-2-il pirimidini in pirazini kot modulatorji histamin H4 receptorja
WO2008067549A2 (en) * 2006-11-30 2008-06-05 Transcept Pharmaceuticals, Inc. Stabilized zolpidem pharmaceutical compositions
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
JP2011526911A (ja) * 2008-06-30 2011-10-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ベンゾイミダゾール−２−イルピリミジン誘導体を製造する方法
SI3133070T1 (sl) 2009-11-27 2019-11-29 Genzyme Corp Eliglustat (GENZ 112638) kot inhibitor sintaze glukozilceramida za uporabo v postopku zdravljenja Fabrjyeve ali Gaucherjeve bolezni, kjer postopek obsega prilagajanje individualnega terapevtskega odmerka metabolizmu P-450 pacienta
WO2011115069A1 (ja) * 2010-03-19 2011-09-22 第一三共株式会社 結晶の網羅的探索
JP6471103B2 (ja) 2013-03-06 2019-02-13 ヤンセン ファーマシューティカ エヌ．ベー． ヒスタミンｈ４受容体のベンゾイミダゾール−２−イルピリミジンモジュレータ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
FR2408345A1 (fr) * 1976-11-30 1979-06-08 Besins Jean Louis Nouvelle composition a action anti-conceptionnelle
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
DE3018940A1 (de) * 1980-05-17 1981-11-26 Hoechst Ag, 6000 Frankfurt Verwendung eines vinylchlorid-pfropf-copolymerisates in der plastisolverarbeitung
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
US4675323A (en) * 1985-08-06 1987-06-23 Synthelabo Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
SE457326B (sv) * 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
EP0289371B1 (fr) * 1987-03-27 1991-09-25 Synthelabo Dérivés d'imidazopyridines, leur préparation et leur application en thérapeutique
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
ES2195510T3 (es) * 1999-03-25 2003-12-01 Synthon Bv Derivados de imidazopiridina y procedimiento para prepararlos.
ES2240074T3 (es) * 1999-03-25 2005-10-16 Synthon B.V. Sales de zolpidem.
WO2001042239A1 (fr) * 1999-12-13 2001-06-14 Sumika Fine Chemicals Co., Ltd. Procede de preparation d'un compose pyridinemethanol

Also Published As

Publication number Publication date
DE60122944T2 (de) 2007-04-12
EP1292304A1 (en) 2003-03-19
YU79402A (sh) 2006-03-03
KR20030069796A (ko) 2003-08-27
US20070037843A1 (en) 2007-02-15
DE20122435U1 (de) 2005-10-06
US20020077332A1 (en) 2002-06-20
PT1541146E (pt) 2007-01-31
ES2238941T1 (es) 2005-09-16
DE60122216D1 (de) 2006-09-21
DE60122216T2 (de) 2007-08-30
AU5721301A (en) 2001-11-07
ATE335481T1 (de) 2006-09-15
HRP20020909A2 (en) 2004-08-31
ATE308324T1 (de) 2005-11-15
DE60125429T2 (de) 2007-09-27
ES2239558T1 (es) 2005-10-01
PT1475093E (pt) 2006-11-30
ES2277301T3 (es) 2007-07-01
AU2001257213B2 (en) 2005-09-29
DE60125429D1 (de) 2007-02-01
ES2238941T3 (es) 2007-04-01
HUP0300701A2 (hu) 2003-07-28
WO2001080857A1 (en) 2001-11-01
US20040220213A1 (en) 2004-11-04
ATE348613T1 (de) 2007-01-15
US20040220211A1 (en) 2004-11-04
US20040220212A1 (en) 2004-11-04
US20040220210A1 (en) 2004-11-04
CZ20023775A3 (cs) 2003-10-15
ATE338550T1 (de) 2006-09-15
DE60122944D1 (de) 2006-10-19
IL152411A0 (en) 2003-05-29
SE5292304T3 (pt) 2005-11-02
CA2406982A1 (en) 2001-11-01
JP2006249105A (ja) 2006-09-21
ES2248321T3 (es) 2006-03-16
JP2006137778A (ja) 2006-06-01
PL358548A1 (en) 2004-08-09
US20040214858A1 (en) 2004-10-28
JP2003531173A (ja) 2003-10-21
DE60114617T2 (de) 2006-07-27
NZ522015A (en) 2004-08-27
EP1292304A4 (en) 2003-07-23
SK16372002A3 (sk) 2003-04-01
ES2239558T3 (es) 2007-04-01
DE60114617D1 (de) 2005-12-08
DK1292304T3 (da) 2005-12-19
DE04010435T1 (de) 2005-09-01
US20040214859A1 (en) 2004-10-28
WO2001080857A9 (en) 2002-06-27
DE04010651T1 (de) 2005-09-01
EP1292304B1 (en) 2005-11-02

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