ATE335481T1 - Zolpidem hemitartrat solvat - Google Patents

Zolpidem hemitartrat solvat

Info

Publication number
ATE335481T1
ATE335481T1 AT04010435T AT04010435T ATE335481T1 AT E335481 T1 ATE335481 T1 AT E335481T1 AT 04010435 T AT04010435 T AT 04010435T AT 04010435 T AT04010435 T AT 04010435T AT E335481 T1 ATE335481 T1 AT E335481T1
Authority
AT
Austria
Prior art keywords
solvat
zolpidem hemitartrate
hemitartrate
zolpidem
polymorphs
Prior art date
Application number
AT04010435T
Other languages
English (en)
Inventor
Judith Aronhime
David Leonov
Erzebet Meszaros-Sos
Szaboles Salyi
Csaba Szabo
Shlomo Zavurov
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27394001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE335481(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE335481T1 publication Critical patent/ATE335481T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Amplifiers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
AT04010435T 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat ATE335481T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19929800P 2000-04-24 2000-04-24
US20602500P 2000-05-22 2000-05-22
US22536400P 2000-08-14 2000-08-14

Publications (1)

Publication Number Publication Date
ATE335481T1 true ATE335481T1 (de) 2006-09-15

Family

ID=27394001

Family Applications (4)

Application Number Title Priority Date Filing Date
AT04010651T ATE338550T1 (de) 2000-04-24 2001-04-24 Mikronisierter zolpidem hemitartrat
AT04010435T ATE335481T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat
AT01930705T ATE308324T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat
AT05001922T ATE348613T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04010651T ATE338550T1 (de) 2000-04-24 2001-04-24 Mikronisierter zolpidem hemitartrat

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT01930705T ATE308324T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat
AT05001922T ATE348613T1 (de) 2000-04-24 2001-04-24 Zolpidem hemitartrat solvat

Country Status (21)

Country Link
US (8) US20020077332A1 (de)
EP (1) EP1292304B1 (de)
JP (3) JP2003531173A (de)
KR (1) KR20030069796A (de)
AT (4) ATE338550T1 (de)
AU (2) AU2001257213B2 (de)
CA (1) CA2406982A1 (de)
CZ (1) CZ20023775A3 (de)
DE (7) DE20122435U1 (de)
DK (1) DK1292304T3 (de)
ES (4) ES2277301T3 (de)
HR (1) HRP20020909A2 (de)
HU (1) HUP0300701A2 (de)
IL (1) IL152411A0 (de)
NZ (1) NZ522015A (de)
PL (1) PL358548A1 (de)
PT (3) PT1473036E (de)
SE (1) SE5292304T3 (de)
SK (1) SK16372002A3 (de)
WO (1) WO2001080857A1 (de)
YU (1) YU79402A (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1370515A2 (de) 2000-08-29 2003-12-17 Ranbaxy Laboratories, Ltd. Synthese von n.n-dimethyl-3-(4-methyl)benzoyl propionamide, einem schlüsselzwischenprodukt von zolpidem
US6869970B2 (en) 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
EP1575952B1 (de) 2002-12-18 2009-02-18 Mallinckrodt Inc. Synthese von heteroaryl acetamiden
WO2004087703A1 (en) * 2003-03-12 2004-10-14 Sun Pharmaceutical Industries Limited Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
EP1660496A1 (de) * 2003-07-31 2006-05-31 Ranbaxy Laboratories Limited Verfahren zur synthese von zolpidem
US7658945B2 (en) * 2004-02-17 2010-02-09 Transcept Pharmaceuticals, Inc. Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
BRPI0609984A2 (pt) * 2005-05-25 2010-05-18 Transcept Pharmaceuticals Inc uso de zolpidem ou um sal do mesmo
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
RU2008110477A (ru) * 2005-08-19 2009-09-27 Авентис Фармасьютикалз Инк. (Us) Комбинация снотворного и r (+)-а-(2, 3-диметоксифенил)-1-[2-(4-фторфенил)этил]-4-пиперидинметанола и его терапевтическое применение
ATE447400T1 (de) * 2005-08-19 2009-11-15 Aventis Pharma Inc Kombination aus einem hypnotischen mittel und einer substituierten bis-aryl- und heteroaryl- verbindung und ihre therapeutische anwendung
CA2624340A1 (en) * 2005-10-03 2007-04-12 Mallinckrodt Inc. Process for preparing zolpidem hemitartrate and tartrate polymorphs
JP2009511627A (ja) * 2005-10-17 2009-03-19 マリンクロッド・インコーポレイテッド 錠剤マトリックスにおけるゾルピデムの多形転移
US20070098788A1 (en) * 2005-10-28 2007-05-03 Gore Subhash P Non-benzodiazepine hypnotic compositions
BRPI0710083A2 (pt) 2006-03-31 2011-08-02 Janssen Pharmaceutica Nv entidade quìmica benzoimidazol-2-il pirimidina e pirazina, composição farmacêutica e uso destas
US20080132535A1 (en) * 2006-11-30 2008-06-05 Transcept Pharmaceuticals, Inc. Stabilized Zolpidem Pharmaceutical Compositions
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
NZ590169A (en) * 2008-06-30 2012-05-25 Janssen Pharmaceutica Nv Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives
SI2796457T1 (sl) 2009-11-27 2016-10-28 Genzyme Corporation Genz 112638 za zdravljenje Gaucherjeve ali Fabryjeve bolezni v kombinirani terapiji
WO2011115069A1 (ja) * 2010-03-19 2011-09-22 第一三共株式会社 結晶の網羅的探索
HUE047681T2 (hu) * 2013-03-06 2020-05-28 Janssen Pharmaceutica Nv A hisztamin H4 receptor benzimidazol-2-il-pirimidin modulátorai
CN116283958A (zh) * 2021-12-03 2023-06-23 山东新时代药业有限公司 唑吡坦共晶体及其制备方法
CN116283957A (zh) * 2021-12-03 2023-06-23 山东新时代药业有限公司 唑吡坦水合物及其制备方法
CN117907368A (zh) * 2024-01-27 2024-04-19 鲁南贝特制药有限公司 一种酒石酸唑吡坦药用晶型d中晶型a、e的定量测定方法
CN118750459B (zh) * 2024-07-22 2025-04-01 常州市武进中医医院 一种酒石酸唑吡坦片及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
FR2408345A1 (fr) * 1976-11-30 1979-06-08 Besins Jean Louis Nouvelle composition a action anti-conceptionnelle
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
IT1130924B (it) * 1980-03-06 1986-06-18 Secifarma Spa Procedimento per la preparazione di spironolattone micronizzato
DE3018940A1 (de) * 1980-05-17 1981-11-26 Hoechst Ag, 6000 Frankfurt Verwendung eines vinylchlorid-pfropf-copolymerisates in der plastisolverarbeitung
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
US4675323A (en) * 1985-08-06 1987-06-23 Synthelabo Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
SE457326B (sv) * 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
ES2026666T3 (es) * 1987-03-27 1992-05-01 Synthelabo Procedimiento para preparar derivados de imidazopiridinas.
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
ATE297924T1 (de) * 1999-03-25 2005-07-15 Synthon Bv Zolpidem salze
ATE242241T1 (de) * 1999-03-25 2003-06-15 Synthon Bv Imidazopyridinderivate und verfahren zu ihrer herstellung
WO2001042239A1 (en) * 1999-12-13 2001-06-14 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a pyridinemethanol compound

Also Published As

Publication number Publication date
NZ522015A (en) 2004-08-27
US20040220211A1 (en) 2004-11-04
JP2006137778A (ja) 2006-06-01
US20020077332A1 (en) 2002-06-20
AU2001257213B2 (en) 2005-09-29
US20040220213A1 (en) 2004-11-04
ATE348613T1 (de) 2007-01-15
ES2238941T3 (es) 2007-04-01
ES2239558T3 (es) 2007-04-01
DE60114617T2 (de) 2006-07-27
DE20122435U1 (de) 2005-10-06
ES2238941T1 (es) 2005-09-16
JP2006249105A (ja) 2006-09-21
ES2248321T3 (es) 2006-03-16
ES2277301T3 (es) 2007-07-01
IL152411A0 (en) 2003-05-29
WO2001080857A1 (en) 2001-11-01
JP2003531173A (ja) 2003-10-21
DE60125429T2 (de) 2007-09-27
DE60114617D1 (de) 2005-12-08
SE5292304T3 (de) 2005-11-02
KR20030069796A (ko) 2003-08-27
PT1473036E (pt) 2006-10-31
WO2001080857A9 (en) 2002-06-27
AU5721301A (en) 2001-11-07
ATE308324T1 (de) 2005-11-15
PT1541146E (pt) 2007-01-31
PT1475093E (pt) 2006-11-30
DE60122216T2 (de) 2007-08-30
DE60122216D1 (de) 2006-09-21
EP1292304A4 (de) 2003-07-23
ES2239558T1 (es) 2005-10-01
DE60122944D1 (de) 2006-10-19
US20040220210A1 (en) 2004-11-04
US20070037843A1 (en) 2007-02-15
DE60125429D1 (de) 2007-02-01
HUP0300701A2 (hu) 2003-07-28
CA2406982A1 (en) 2001-11-01
DK1292304T3 (da) 2005-12-19
US20040214859A1 (en) 2004-10-28
DE04010651T1 (de) 2005-09-01
SK16372002A3 (sk) 2003-04-01
ATE338550T1 (de) 2006-09-15
DE04010435T1 (de) 2005-09-01
DE60122944T2 (de) 2007-04-12
EP1292304A1 (de) 2003-03-19
YU79402A (sh) 2006-03-03
PL358548A1 (en) 2004-08-09
CZ20023775A3 (cs) 2003-10-15
US20040220212A1 (en) 2004-11-04
US20040214858A1 (en) 2004-10-28
EP1292304B1 (de) 2005-11-02
HRP20020909A2 (en) 2004-08-31

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