ATE341647T1 - Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion - Google Patents

Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion

Info

Publication number
ATE341647T1
ATE341647T1 AT01974720T AT01974720T ATE341647T1 AT E341647 T1 ATE341647 T1 AT E341647T1 AT 01974720 T AT01974720 T AT 01974720T AT 01974720 T AT01974720 T AT 01974720T AT E341647 T1 ATE341647 T1 AT E341647T1
Authority
AT
Austria
Prior art keywords
self
probes
regions
oligonucleotides
forming
Prior art date
Application number
AT01974720T
Other languages
English (en)
Inventor
Mitsugu Usui
Mari Mitsuka
Chikako Hakii
Original Assignee
Sanko Junyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanko Junyaku Kk filed Critical Sanko Junyaku Kk
Application granted granted Critical
Publication of ATE341647T1 publication Critical patent/ATE341647T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT01974720T 2000-10-11 2001-10-05 Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion ATE341647T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000311151 2000-10-11

Publications (1)

Publication Number Publication Date
ATE341647T1 true ATE341647T1 (de) 2006-10-15

Family

ID=18790969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01974720T ATE341647T1 (de) 2000-10-11 2001-10-05 Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion

Country Status (8)

Country Link
US (1) US7122310B2 (de)
EP (1) EP1304386B1 (de)
JP (1) JP3912595B2 (de)
AT (1) ATE341647T1 (de)
AU (1) AU2001294199A1 (de)
DE (1) DE60123626T2 (de)
ES (1) ES2273892T3 (de)
WO (1) WO2002031192A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2317893T3 (es) * 2000-03-31 2009-05-01 Sanko Junyaku Co., Ltd. Sondas para construir polimeros de sondas, procedimiento para construir un polimero de sondas y uso del mismo.
AU7873001A (en) * 2000-08-30 2002-03-13 Sanko Junyaku Co., Ltd. Method of detecting gene
CA2515734C (en) * 2003-02-14 2013-04-09 Eisai Co., Ltd. Signal amplification method for detecting expressed gene
CN100547080C (zh) * 2004-04-28 2009-10-07 卫材R&D管理有限公司 杂交方法
JPWO2006028162A1 (ja) * 2004-09-08 2008-05-08 エーザイ・アール・アンド・ディー・マネジメント株式会社 シグナルプローブポリマーの形成方法
JPWO2007108378A1 (ja) 2006-03-15 2009-08-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 シグナルプローブポリマーの形成方法
US9315536B2 (en) * 2006-08-29 2016-04-19 Creatrone, Inc. Self-assembling oligonucleotides and methods
US8450058B2 (en) 2007-08-14 2013-05-28 Eisai R&D Management Co., Ltd. Method of detecting target substance
US20100256007A1 (en) 2007-10-24 2010-10-07 Mitsugu Usui Nucleic acid probe, and method of forming probe-polymer
EP2213751A1 (de) 2007-10-31 2010-08-04 Eisai R&D Management Co., Ltd. Polymer zur erkennung einer zielsubstanz und verfahren zur erkennung einer zielsubstanz
JP2012070635A (ja) * 2009-01-29 2012-04-12 Eisai R & D Management Co Ltd 核酸の検出方法
JP5712382B2 (ja) * 2010-03-31 2015-05-07 学校法人東京理科大学 生体分子相互作用解析ツールの構成とそれを用いた解析方法
EP2789688A4 (de) 2011-12-09 2015-07-15 Eisai R&D Man Co Ltd Verfahren zur erkennung von nukleotidmutation und nachweiskit
EP2851425A1 (de) 2012-05-15 2015-03-25 Eisai R&D Management Co., Ltd. Rna-nachweisverfahren und -nachweiskit
WO2013177046A1 (en) 2012-05-21 2013-11-28 Solulink, Inc. Methods and/or use of oligonucleotide conjugates for suppressing background due to cross-hybridization
WO2020087166A1 (en) * 2018-10-30 2020-05-07 Institut National De La Recherche Scientifique Self-assembling nucleic acid surfaces for biosensor applications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175270A (en) 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
CA2039517C (en) 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
DE69834645T2 (de) 1997-07-29 2007-05-03 Polyprobe, Inc. Dendritische nukleinsäuren mit maximaler selbstzusammenlagerung
JP3267576B2 (ja) * 1998-11-09 2002-03-18 三光純薬株式会社 プローブ高分子の形成方法

Also Published As

Publication number Publication date
WO2002031192A1 (fr) 2002-04-18
DE60123626T2 (de) 2007-01-18
US7122310B2 (en) 2006-10-17
AU2001294199A1 (en) 2002-04-22
US20030087262A1 (en) 2003-05-08
EP1304386A1 (de) 2003-04-23
DE60123626D1 (de) 2006-11-16
EP1304386B1 (de) 2006-10-04
EP1304386A4 (de) 2005-01-19
ES2273892T3 (es) 2007-05-16
JP3912595B2 (ja) 2007-05-09
JPWO2002031192A1 (ja) 2004-02-19

Similar Documents

Publication Publication Date Title
ATE341647T1 (de) Verfahren zur konstruktion von selbstassembierenden sonden und verfahren zu ihrer detektion
DE69233630T2 (de) Sätze von HIV-Sonden zur Verwendung in Sandwich-Hydridisierungsassays in Lösungsphase
CA2572472C (en) Methods and compositions to detect nucleic acids in a biological sample
US20010019835A1 (en) Gene amplifying method
CN101142325A (zh) 制备用于分析的多核苷酸的方法
CN101541978B (zh) 核酸探针以及检测疟原虫寄生虫的方法
WO1999061665A2 (en) Solution hybridization of nucleic acids with antisense probes having modified backbones
ES2097768T3 (es) Amplificacion de la señal de una sonda de adn.
EP1072679A3 (de) Methode zur Herstelung von Nucleinsäuremolekülen mit einer reduzierten Sekundärstruktur
EP1464710A3 (de) Eine Detektionsprobe und eine Reihe von Detektionsproben für Infektionserreger, ein Träger und eine genetische Uberprüfungsmethode
WO1993016094A3 (en) Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides
CN104603290B (zh) 用于检测核苷酸变异的核酸酶保护方法
ATE466864T1 (de) Nichtaggregierende, nichtausschaltende oligomere, nukleotid-analoga enthaltend; verfahren zu deren herstellung und verwendung
HU221237B1 (en) Solution phase nucleic acid sandwich assays having reduced background noise
CA2839705A1 (en) Multivariate diagnostic assays and methods for using same
RU2004120769A (ru) Олигонуклеотид, контролирующий область гибридизации, и его применение
ATE194391T1 (de) Amplifikationsoligonukleotide und sonden für borrelia, die mit lyme kranheit assoziiert sind
CN108138221A (zh) 用于检测核酸的超高灵敏度探针
CN106536735A (zh) 分析dna样品的探针集合和使用所述探针集合的方法
DE60143314D1 (de) Estimmung der präsenz von cryptosporidium organismen in einer testprobe
WO1999016780A3 (en) Genetic sequences, diagnostic and/or quantification methods for the identification of staphylococci strains
DE19824900B4 (de) DNA-Nachweis über einen Strangreassoziationskomplex
WO2005047468A8 (en) Improved methods for detecting and measuring specific nucleic acid sequences
EP1480155A3 (de) Informationsverarbeitungsanlage, Informationsverarbeitungsverfahren, Speichermedium und Programm
EP1799860B1 (de) Dna-fingerabdrucktechnik unter verwendung eines branch-migration-tests

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties