ATE319475T1 - Microbielles wirkstoffabgabesystem - Google Patents
Microbielles wirkstoffabgabesystemInfo
- Publication number
- ATE319475T1 ATE319475T1 AT00982485T AT00982485T ATE319475T1 AT E319475 T1 ATE319475 T1 AT E319475T1 AT 00982485 T AT00982485 T AT 00982485T AT 00982485 T AT00982485 T AT 00982485T AT E319475 T1 ATE319475 T1 AT E319475T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- allergic
- allergens
- subjects
- microorganisms
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 206010020751 Hypersensitivity Diseases 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 4
- 244000005700 microbiome Species 0.000 abstract 3
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 230000002052 anaphylactic effect Effects 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000001048 venom Anatomy 0.000 abstract 1
- 239000002435 venom Substances 0.000 abstract 1
- 231100000611 venom Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19503500P | 2000-04-06 | 2000-04-06 | |
| US09/731,375 US8153414B2 (en) | 2000-04-06 | 2000-12-06 | Microbial delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319475T1 true ATE319475T1 (de) | 2006-03-15 |
Family
ID=26890647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00982485T ATE319475T1 (de) | 2000-04-06 | 2000-12-06 | Microbielles wirkstoffabgabesystem |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US8153414B2 (enExample) |
| EP (1) | EP1272213B1 (enExample) |
| JP (3) | JP2004527450A (enExample) |
| AT (1) | ATE319475T1 (enExample) |
| AU (2) | AU2001219510B2 (enExample) |
| CA (1) | CA2403292C (enExample) |
| CY (1) | CY1105216T1 (enExample) |
| DE (1) | DE60026584T2 (enExample) |
| DK (1) | DK1272213T3 (enExample) |
| ES (1) | ES2260078T3 (enExample) |
| WO (1) | WO2001066136A2 (enExample) |
Families Citing this family (57)
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| ES2260078T3 (es) * | 2000-04-06 | 2006-11-01 | Seer Pharmaceuticals, Llc. | Sistema de administracion microbiana. |
| US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
| EP1278550A4 (en) * | 2000-04-07 | 2004-05-12 | Univ California | SYNERGISTIC IMPROVEMENTS OF POLYNUCLEOTIDE VACCINE |
| US7083787B2 (en) * | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
| US7060687B2 (en) | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
| US7439042B2 (en) * | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| AU2003301021C1 (en) * | 2002-12-16 | 2010-02-18 | Globelmmune, Inc. | Yeast-based vaccines as immunotherapy |
| US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| US20070231796A1 (en) * | 2003-09-17 | 2007-10-04 | The Regents Of The University Of California | Sensor and method for detection of a target substance |
| JP5234445B2 (ja) * | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
| AU2005295317B2 (en) * | 2004-10-18 | 2011-10-13 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US20100034840A1 (en) * | 2005-07-11 | 2010-02-11 | David Apelian | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) * | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| CN101448848B (zh) * | 2006-03-27 | 2013-12-04 | 全球免疫股份有限公司 | Ras突变及其相关组合物和方法 |
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| ES2950396T3 (es) | 2008-02-01 | 2023-10-09 | Prota Therapeutics Pty Ltd | Un método para inducir tolerancia a un alérgeno |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
| EP2419126B1 (en) | 2009-04-17 | 2018-01-10 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| WO2011008735A1 (en) * | 2009-07-13 | 2011-01-20 | Vaxgene Corporation | Oral vaccines produced and administered using edible micro-organism |
| JP5913103B2 (ja) | 2009-09-14 | 2016-04-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate | 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法 |
| US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
| US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
| EP2651439B1 (en) | 2010-12-17 | 2018-09-19 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| AP2013007110A0 (en) | 2011-02-12 | 2013-09-30 | Globeimmune Inc | Yeast-based therapeutic for chronic hepatitis B infection |
| AU2012228937B2 (en) | 2011-03-17 | 2016-11-03 | Globeimmune, Inc. | Yeast-Brachyury immunotherapeutic compositions |
| BR112013032381B1 (pt) | 2011-06-14 | 2021-01-12 | Globeimmune, Inc. | composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta |
| RU2017143985A (ru) | 2011-08-17 | 2019-02-14 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения |
| US20130216589A1 (en) * | 2012-02-17 | 2013-08-22 | Rich Content Biotech INC. | Oral vaccine for aquatic animals |
| US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| EP2864792A1 (en) | 2012-06-26 | 2015-04-29 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
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| US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
| US9492535B2 (en) | 2013-03-14 | 2016-11-15 | Aimmune Therapeutics, Inc. | Peanut formulations and uses thereof |
| SI2968529T1 (sl) | 2013-03-14 | 2021-03-31 | Aimmune Therapeutics, Inc. | Izdelava arašidovih formulacij arašida za ustno desenzibilizacijo |
| WO2014186047A1 (en) | 2013-03-19 | 2014-11-20 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
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| EP3760223A1 (en) | 2013-04-03 | 2021-01-06 | N-Fold Llc | Nanoparticle composition for desensitizing a subject to peanut allergens |
| TWI654200B (zh) | 2013-08-30 | 2019-03-21 | 環球免疫公司 | 治療或預防結核病的組合物及方法 |
| AU2015241380B2 (en) | 2014-04-03 | 2020-11-26 | AllerGenis LLC | Peptides, reagents and methods for detecting food allergy |
| KR102409372B1 (ko) | 2014-04-11 | 2022-06-16 | 글로브이뮨 | 효모 면역 요법 및 타입 i 인터페론 감도 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2017023840A1 (en) | 2015-08-03 | 2017-02-09 | Globeimmune, Inc. | Modified yeast-brachyury immunotherapeutic compositions |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| CA3080253A1 (en) * | 2017-10-25 | 2019-05-02 | Allero Therapeutics Bv | Treatment of immune diseases by administration of antigen-specific formulations |
| CA3080601A1 (en) | 2017-11-02 | 2019-05-09 | Aimmune Therapeutics, Inc. | Methods of oral immunotherapy |
| CN119818663A (zh) | 2018-05-15 | 2025-04-15 | 全球免疫公司 | 用于诱导细胞免疫应答的重组酵母裂解物 |
| EP3836801A4 (en) | 2018-08-16 | 2022-05-18 | Société des Produits Nestlé S.A. | Peanut oral immunotherapy with maintenance dose |
| CN113891722A (zh) | 2018-12-20 | 2022-01-04 | 爱沐疗法公司 | 用于漏服剂量的花生口服免疫疗法给药计划表 |
| EP3965815A4 (en) | 2019-05-10 | 2023-05-31 | Société des Produits Nestlé S.A. | METHOD OF IMPROVING THE QUALITY OF LIFE IN A PEANUT ALLERGY PATIENT |
| US20210247404A1 (en) * | 2020-02-06 | 2021-08-12 | AllerGenis LLC | Assays For Detecting Peanut Allergies |
| WO2025212530A1 (en) | 2024-04-01 | 2025-10-09 | N-Fold Llc | Nanoparticle manufacturing |
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-
2000
- 2000-12-06 ES ES00982485T patent/ES2260078T3/es not_active Expired - Lifetime
- 2000-12-06 DK DK00982485T patent/DK1272213T3/da active
- 2000-12-06 CA CA2403292A patent/CA2403292C/en not_active Expired - Fee Related
- 2000-12-06 AU AU2001219510A patent/AU2001219510B2/en not_active Ceased
- 2000-12-06 AU AU1951001A patent/AU1951001A/xx active Pending
- 2000-12-06 AT AT00982485T patent/ATE319475T1/de active
- 2000-12-06 WO PCT/US2000/033121 patent/WO2001066136A2/en not_active Ceased
- 2000-12-06 JP JP2001564788A patent/JP2004527450A/ja active Pending
- 2000-12-06 DE DE60026584T patent/DE60026584T2/de not_active Expired - Lifetime
- 2000-12-06 EP EP00982485A patent/EP1272213B1/en not_active Expired - Lifetime
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- 2003-12-04 US US10/728,323 patent/US20040208894A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2403292A1 (en) | 2001-09-13 |
| EP1272213A2 (en) | 2003-01-08 |
| AU1951001A (en) | 2001-09-17 |
| US20130243814A1 (en) | 2013-09-19 |
| US20040208894A1 (en) | 2004-10-21 |
| US20110027298A1 (en) | 2011-02-03 |
| DE60026584D1 (de) | 2006-05-04 |
| US8153414B2 (en) | 2012-04-10 |
| US20030035810A1 (en) | 2003-02-20 |
| DK1272213T3 (da) | 2006-07-10 |
| US8815251B2 (en) | 2014-08-26 |
| DE60026584T2 (de) | 2007-03-08 |
| ES2260078T3 (es) | 2006-11-01 |
| JP2012207032A (ja) | 2012-10-25 |
| WO2001066136A3 (en) | 2001-12-27 |
| CA2403292C (en) | 2011-02-08 |
| US20040234548A1 (en) | 2004-11-25 |
| EP1272213B1 (en) | 2006-03-08 |
| US20130142817A1 (en) | 2013-06-06 |
| WO2001066136A2 (en) | 2001-09-13 |
| JP2004527450A (ja) | 2004-09-09 |
| JP2009242427A (ja) | 2009-10-22 |
| CY1105216T1 (el) | 2010-03-03 |
| AU2001219510B2 (en) | 2007-06-14 |
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