ATE311867T1 - Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen - Google Patents

Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen

Info

Publication number
ATE311867T1
ATE311867T1 AT98944449T AT98944449T ATE311867T1 AT E311867 T1 ATE311867 T1 AT E311867T1 AT 98944449 T AT98944449 T AT 98944449T AT 98944449 T AT98944449 T AT 98944449T AT E311867 T1 ATE311867 T1 AT E311867T1
Authority
AT
Austria
Prior art keywords
pain
novel combinations
antepileptic
drugs
directed
Prior art date
Application number
AT98944449T
Other languages
German (de)
English (en)
Inventor
Leslie Magnus-Miller
Douglas A Saltel
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE311867T1 publication Critical patent/ATE311867T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AT98944449T 1997-09-08 1998-08-18 Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen ATE311867T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5820797P 1997-09-08 1997-09-08
PCT/US1998/017083 WO1999012537A1 (en) 1997-09-08 1998-08-18 Analgesic compositions comprising anti-epileptic compounds and methods of using same

Publications (1)

Publication Number Publication Date
ATE311867T1 true ATE311867T1 (de) 2005-12-15

Family

ID=22015361

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944449T ATE311867T1 (de) 1997-09-08 1998-08-18 Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen

Country Status (20)

Country Link
US (3) US6593368B2 (https=)
EP (1) EP1011658B1 (https=)
JP (1) JP3782935B2 (https=)
KR (1) KR100537707B1 (https=)
AT (1) ATE311867T1 (https=)
AU (1) AU750578B2 (https=)
BR (1) BR9812162A (https=)
CA (1) CA2296336C (https=)
CU (1) CU23226B7 (https=)
DE (1) DE69832712T2 (https=)
DK (1) DK1011658T3 (https=)
ES (1) ES2253825T3 (https=)
HU (1) HU226165B1 (https=)
IL (2) IL134165A0 (https=)
IS (1) IS5362A (https=)
NO (1) NO324122B1 (https=)
NZ (1) NZ502671A (https=)
PL (1) PL339142A1 (https=)
WO (1) WO1999012537A1 (https=)
ZA (1) ZA988159B (https=)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL126999A (en) 1996-07-24 2002-03-10 Warner Lambert Co Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
WO1999012537A1 (en) * 1997-09-08 1999-03-18 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
EP1094817A1 (en) * 1998-07-09 2001-05-02 Warner-Lambert Company Compositions comprising gaba analogs and caffeine
US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
DE60022333T2 (de) 1999-04-09 2006-07-06 Euro-Celtique S.A. Natrium kanalblocker zusammensetzungen und deren verwendung
AU5824800A (en) * 1999-06-23 2001-01-31 Warner-Lambert Company Use of fosphenytoin for the treatment of acute neuropathic pain
HUP0203198A3 (en) * 1999-08-20 2005-07-28 Ortho Mcneil Pharm Inc Pharmaceutical composition comprising a tramadol material and an anticonvulsant drug, process for its preparation and its use
IL160523A0 (en) 2001-09-03 2004-07-25 Newron Pharm Spa PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
US7612112B2 (en) * 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US6730667B2 (en) * 2001-11-26 2004-05-04 William R. Deagle Iontophoresis disc pain blocker
WO2003066040A1 (en) 2002-02-05 2003-08-14 Ajinomoto Co.,Inc. Medicinal compositions containing gabapentin or pregabalin and n-type calcium channel antagonist
RU2286151C2 (ru) * 2002-02-22 2006-10-27 Уорнер-Ламберт Компани Ллс Комбинации альфа-2-дельта-лиганда с селективным ингибитором циклооксигеназы-2
WO2004054560A1 (en) * 2002-12-13 2004-07-01 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
FR2862875B1 (fr) * 2003-12-02 2006-04-07 Mathey Acoustique Service Preparation pharmaceutique pour le traitement des acouphenes
KR20070086334A (ko) * 2004-11-16 2007-08-27 리머릭 뉴로사이언스즈, 인크. 통증을 치료하기 위한 방법 및 조성물
US20070087977A1 (en) * 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
KR20070087596A (ko) 2005-09-19 2007-08-28 테바 파마슈티컬 인더스트리즈 리미티드 (s)-(+)-3-(아미노메틸)-5-메틸헥산산의 비대칭 합성
MXPA05011735A (es) * 2005-11-01 2007-04-30 Leopoldo Espinosa Abdala Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico.
US20090176882A1 (en) * 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
CA2673545A1 (en) * 2006-12-22 2008-07-03 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
MX2007006091A (es) * 2007-05-21 2009-02-25 World Trade Imp Export Wtie Ag Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante.
WO2009021058A2 (en) * 2007-08-06 2009-02-12 Trinity Labortories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
US20100087525A1 (en) * 2008-06-23 2010-04-08 Lilach Hedvati Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
FR2934267B1 (fr) * 2008-07-23 2010-08-13 Pharmaleads Derives aminophosphiniques utiles dans le traitement de la douleur
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
EP2334176A4 (en) 2008-09-27 2012-05-02 Taraxos Inc TOPICAL FORMULATIONS FOR THE TREATMENT OF NERVE DISEASES
CN105330603A (zh) 2008-10-08 2016-02-17 凯飞药业公司 Gaba偶联物及其使用方法
CA2805371C (en) * 2010-07-30 2017-10-31 Toray Industries, Inc. Therapeutic agent or prophylactic agent for neuropathic pain
WO2013076339A1 (es) * 2011-11-22 2013-05-30 Servicio Andaluz De Salud Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia
WO2013103826A1 (en) * 2012-01-06 2013-07-11 Skyview Enterprise Ltd. Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation
FR2998892B1 (fr) 2012-12-04 2015-01-02 Pf Medicament Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments
MX378004B (es) 2015-12-02 2025-03-10 Jaime Samuel CHAIT AUERBACH Composición oral veterinaria con gabapentina.
KR102631399B1 (ko) * 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
MX384760B (es) 2018-07-04 2025-03-14 Federico Amezcua Amezcua Combinación farmacéutica sinérgica del enantiómero activo s-ketorolaco y gabapentina para el tratamiento del dolor neuropático.
MX388067B (es) * 2019-07-16 2025-03-19 Federico Amezcua Amezcua Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico
US11147780B2 (en) * 2020-02-24 2021-10-19 Algia Pharma, Llc Multidrug pain management package

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE634102A (https=) *
DE1963925C3 (de) * 1969-12-20 1975-07-10 Desitin-Werk, Carl Klinke Gmbh, 2000 Hamburg Verfahren zur Herstellung von N hoch 3-Carbalkoxyderivaten des 5,5-Diphenylhydantoins
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
JPS54110334A (en) * 1978-02-16 1979-08-29 Fuji Chem Ind Co Ltd Novel compounded anodyne and antiiinflammatory agent
JPS61221121A (ja) * 1985-03-27 1986-10-01 Nitto Electric Ind Co Ltd テ−プ製剤
US4694010A (en) * 1985-08-16 1987-09-15 New York University Anticonvulsant compositions and method
AU2929489A (en) 1987-12-22 1989-07-19 John W. FERKANY Dextrorphan potentiator for anticonvulsant composition and method
US6197819B1 (en) * 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
GB9108362D0 (en) * 1991-04-18 1991-06-05 Radoslavov Alexander A pharmaceutical composition suitable for alleviation of headaches,migraine and other painful conditions
JP3856816B2 (ja) 1992-05-20 2006-12-13 ノースウェスターン ユニヴァーシティ 抗発作治療用のgaba及びl−グルタミン酸類縁体
US5234929A (en) * 1992-07-20 1993-08-10 William Chelen Method of treating motion sickness with anticonvulsants and antitussive agents
JPH06100468A (ja) 1992-09-25 1994-04-12 Kibun Food Chemifa Co Ltd 徐放性組成物
US5321012A (en) 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
JPH06227969A (ja) * 1993-02-02 1994-08-16 Masayasu Sugihara 薬品の腸溶性改善方法およびそれにより得られた薬品組成物
US5420270A (en) * 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5352638A (en) 1994-02-22 1994-10-04 Corning Incorporated Nickel aluminosilicate glass-ceramics
FI970865A7 (fi) 1994-09-02 1997-03-14 Univ Virginia Commonwealth Ei-huumaavaa kipulääkeainetta sekä kivun poistamisen tehostajaa sisält ävä, kipua lievittävä koostumus
CN1046199C (zh) * 1994-12-13 1999-11-10 凌吉安 复方消炎止痛霜剂
IL126999A (en) * 1996-07-24 2002-03-10 Warner Lambert Co Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
CA2264182A1 (en) * 1996-08-23 1998-02-26 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
US6057373A (en) 1997-05-22 2000-05-02 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists
US6127418A (en) * 1997-08-20 2000-10-03 Warner-Lambert Company GABA analogs to prevent and treat gastrointestinal damage
WO1999008670A1 (en) * 1997-08-20 1999-02-25 Guglietta, Antonio Gaba analogs to prevent and treat gastrointestinal damage
WO1999012537A1 (en) 1997-09-08 1999-03-18 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same

Also Published As

Publication number Publication date
AU750578B2 (en) 2002-07-25
DK1011658T3 (da) 2006-04-03
DE69832712T2 (de) 2006-06-22
NO20001175L (no) 2000-03-07
CA2296336A1 (en) 1999-03-18
HU226165B1 (en) 2008-05-28
ES2253825T3 (es) 2006-06-01
HUP0003705A2 (hu) 2001-04-28
CU23226B7 (es) 2007-09-26
ZA988159B (en) 1999-03-11
US20020115705A1 (en) 2002-08-22
US20030065028A1 (en) 2003-04-03
NZ502671A (en) 2003-01-31
IS5362A (is) 2000-01-25
CA2296336C (en) 2004-04-20
KR20010023745A (ko) 2001-03-26
US6942876B2 (en) 2005-09-13
US6593368B2 (en) 2003-07-15
JP2001515859A (ja) 2001-09-25
NO324122B1 (no) 2007-08-27
KR100537707B1 (ko) 2005-12-20
IL185345A0 (en) 2008-01-06
NO20001175D0 (no) 2000-03-07
IL134165A0 (en) 2001-04-30
JP3782935B2 (ja) 2006-06-07
WO1999012537A1 (en) 1999-03-18
EP1011658B1 (en) 2005-12-07
AU9198798A (en) 1999-03-29
US20030176505A1 (en) 2003-09-18
DE69832712D1 (de) 2006-01-12
HUP0003705A3 (en) 2002-01-28
BR9812162A (pt) 2000-07-18
PL339142A1 (en) 2000-12-04
EP1011658A1 (en) 2000-06-28

Similar Documents

Publication Publication Date Title
ATE311867T1 (de) Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen
BR0008847A (pt) Composições analgésicas que compreendemcompostos antiepilépticos, e métodos de uso dasmesmas
WO2001091736A3 (en) Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic
WO2001082914A3 (en) Topical anesthetic/opioid formulations and uses thereof
NZ592039A (en) Combination therapy for the treatment of ocular neovascular disorders
MXPA02007690A (es) Composiciones de liberacion controlada que contienen agonista y antiagonista de opioide.
AU4743601A (en) Neutral antagonists and use thereof in treating drug abuse
ATE292982T1 (de) Analgesiche synergie durch gleichzeitige verabreichung von subanalgesichen doseneines mu- opioidanagonisten und eines kappa - 2- opioidanagonisten
GEP20033131B (en) Azabicycloalkanes as CCR5 Modulators, Pharmaceutical Compositions Containing the Same and Their Use for Treatment and Prevention of Diseases Caused by CCR5 Activity
WO2002058620A3 (es) Composiciones farmaceuticas que contienen un inhibidor de cox-ii y un relajante muscular
CA2260943A1 (en) Formulation of 5-ht agonists
EA199800805A1 (ru) Пероральная фармацевтическая форма лекарственного препарата в виде множественной дозированной формы с модифицированным высвобождением
HUP9801591A3 (en) Use of nitric oxide-releasing agents for producing pharmaceutical composition to treat impotency, and delivery device dosage of nitric oxide
ATE423556T1 (de) Capsaicin-enthaltende missbrauchsichere pharmazeutische zusammensetzungen
GEP20022784B (en) Celecoxib Composition
RU2002116361A (ru) Анальгезирующие композиции, содержащие бупренорфин
IL128723A0 (en) Pharmaceutical compositions containing rar antagonists and rxr agonists
RU2001111868A (ru) Антагонисты метаботропных глутаматных рецепторов (mglur5) для лечения боли и состояния тревоги
CA2189916A1 (en) A new regime for paclitaxel in kaposi's sarcoma patients
ATE293451T1 (de) Behandlung der osteoarthritis durch verabreichung von poly-n-acetyl-d-glucosamin
RU94045866A (ru) Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, способ лечения
US20050256187A1 (en) Method and composition for synergistic topical therapy for neuromuscular pains
PL348202A1 (en) Pharmaceutically active composition and dispensing device
CA2400578A1 (en) Controlled-release compositions containing opioid agonist and antagonist
DE69814669D1 (de) Pharmaceutische Zusammensetzung enthaltend (+)-EPHEDRIN und einen H1 Rezeptor Antagonisten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1011658

Country of ref document: EP

REN Ceased due to non-payment of the annual fee