ATE302196T1 - N-adamantylalkyl benzamide derivativen als p2x7- rezeptor antagonisten - Google Patents

N-adamantylalkyl benzamide derivativen als p2x7- rezeptor antagonisten

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Publication number
ATE302196T1
ATE302196T1 AT02257719T AT02257719T ATE302196T1 AT E302196 T1 ATE302196 T1 AT E302196T1 AT 02257719 T AT02257719 T AT 02257719T AT 02257719 T AT02257719 T AT 02257719T AT E302196 T1 ATE302196 T1 AT E302196T1
Authority
AT
Austria
Prior art keywords
adamantylalkyl
receptor antagonists
benzamide derivatives
preparation
derivatives
Prior art date
Application number
AT02257719T
Other languages
English (en)
Inventor
Allen J Duplantier
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE302196T1 publication Critical patent/ATE302196T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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AT02257719T 2001-11-12 2002-11-07 N-adamantylalkyl benzamide derivativen als p2x7- rezeptor antagonisten ATE302196T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33689201P 2001-11-12 2001-11-12

Publications (1)

Publication Number Publication Date
ATE302196T1 true ATE302196T1 (de) 2005-09-15

Family

ID=23318138

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02257719T ATE302196T1 (de) 2001-11-12 2002-11-07 N-adamantylalkyl benzamide derivativen als p2x7- rezeptor antagonisten

Country Status (10)

Country Link
US (1) US6927219B2 (de)
EP (1) EP1310493B1 (de)
JP (1) JP4001542B2 (de)
AT (1) ATE302196T1 (de)
BR (1) BR0204588A (de)
CA (1) CA2411544C (de)
DE (1) DE60205564T2 (de)
ES (1) ES2244733T3 (de)
MX (1) MXPA02009783A (de)
WO (1) WO2003042190A1 (de)

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EP1644041A1 (de) * 2003-05-29 2006-04-12 AstraZeneca AB Pharmazeutische zusammensetzung mit einem p2x7 antagonisten und sulfasalazin
WO2004105796A1 (en) * 2003-05-29 2004-12-09 Astrazeneca Ab A pharmaceutical composition containing a p2x7 receptor antagonist and methotrexate
EP1633401A1 (de) * 2003-05-29 2006-03-15 AstraZeneca AB Pharmazeutische zusammensetzung mit einem p2x7 rezeptor-antagonisten und einem tumornekrosefaktor alpha
GB0312609D0 (en) 2003-06-02 2003-07-09 Astrazeneca Ab Novel compounds
SE0302192D0 (sv) * 2003-08-08 2003-08-08 Astrazeneca Ab Novel compounds
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ITMI20040255A1 (it) * 2004-02-17 2004-05-17 Univ Degli Studi Milano Sostanze ad attivita' antiangiogenica
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JPWO2005107804A1 (ja) * 2004-05-06 2008-03-21 小野薬品工業株式会社 呼吸器疾患治療剤
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WO2006083214A1 (en) * 2005-02-02 2006-08-10 Astrazeneca Ab Pharmaceutical composition comprising a p2x7 receptor antagonist and a hmg-coa reductase inhibitor
JPWO2006104172A1 (ja) * 2005-03-29 2008-09-11 興和株式会社 関節リウマチの予防及び／又は治療薬
WO2007008157A1 (en) * 2005-07-11 2007-01-18 Astrazeneca Ab New combination 2
WO2007008155A1 (en) * 2005-07-11 2007-01-18 Astrazeneca Ab New combination 1
ES2612890T3 (es) 2005-09-01 2017-05-19 F. Hoffmann-La Roche Ag Diaminopirimidinas como moduladores de P2X3 y P2X2/3
WO2007025901A1 (en) * 2005-09-01 2007-03-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
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JPWO2008001499A1 (ja) * 2006-06-29 2009-11-26 興和株式会社 関節リウマチの予防及び／又は治療薬
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