DE602004029462D1 - Isochinolin-3-carbonsäureamide und ihre pharmazeutische verwendung - Google Patents

Isochinolin-3-carbonsäureamide und ihre pharmazeutische verwendung

Info

Publication number
DE602004029462D1
DE602004029462D1 DE602004029462T DE602004029462T DE602004029462D1 DE 602004029462 D1 DE602004029462 D1 DE 602004029462D1 DE 602004029462 T DE602004029462 T DE 602004029462T DE 602004029462 T DE602004029462 T DE 602004029462T DE 602004029462 D1 DE602004029462 D1 DE 602004029462D1
Authority
DE
Germany
Prior art keywords
isochinoline
pharmaceutical use
carboxylic amide
pharmaceuticals
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004029462T
Other languages
English (en)
Inventor
Max Peter Seiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE602004029462D1 publication Critical patent/DE602004029462D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602004029462T 2003-05-12 2004-05-11 Isochinolin-3-carbonsäureamide und ihre pharmazeutische verwendung Expired - Lifetime DE602004029462D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0310867.7A GB0310867D0 (en) 2003-05-12 2003-05-12 Organic compounds
PCT/EP2004/005042 WO2004099206A1 (en) 2003-05-12 2004-05-11 Isoquinoline-3-carboxylic acid amides and pharmaceutical uses thereof

Publications (1)

Publication Number Publication Date
DE602004029462D1 true DE602004029462D1 (de) 2010-11-18

Family

ID=9957894

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004029462T Expired - Lifetime DE602004029462D1 (de) 2003-05-12 2004-05-11 Isochinolin-3-carbonsäureamide und ihre pharmazeutische verwendung

Country Status (12)

Country Link
US (1) US7683075B2 (de)
EP (1) EP1633752B1 (de)
JP (1) JP2006525976A (de)
CN (1) CN100341874C (de)
AT (1) ATE483710T1 (de)
AU (1) AU2004235971C1 (de)
BR (1) BRPI0410233A (de)
CA (1) CA2524625A1 (de)
DE (1) DE602004029462D1 (de)
GB (1) GB0310867D0 (de)
MX (1) MXPA05012154A (de)
WO (1) WO2004099206A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR108325A1 (es) 2016-04-27 2018-08-08 Samumed Llc Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
AR108326A1 (es) 2016-04-27 2018-08-08 Samumed Llc Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
TW202120490A (zh) 2019-07-30 2021-06-01 德商拜耳動物保健有限公司 新穎異喹啉衍生物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311724A1 (de) 1987-10-16 1989-04-19 Synthelabo Anxiolytische R-N-(1-Azabicyclo[2.2.2]oct-3-yl)-benzamide und -thiobenzamide
FR2625678B1 (fr) 1988-01-13 1991-06-07 Delalande Sa Agents anorexigenes a base de n-(quinuclidin-3-yl)-benzamides ou thiobenzamides
EP0353371A1 (de) 1988-08-04 1990-02-07 Synthelabo Steigerung der Gedächtnisleistung durch R-N-(1-azabicyclo[2.2.2]oct-3-yl)Benzamide und Thiobenzamide
DE3878235T2 (de) 1988-08-04 1993-06-03 Synthelabo Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide.
GB9009542D0 (en) 1990-04-27 1990-06-20 Beecham Group Plc Novel compounds
SE9600683D0 (sv) 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
SE0000540D0 (sv) * 2000-02-18 2000-02-18 Astrazeneca Ab New compounds
PE20021019A1 (es) * 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
AR036041A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
CA2460075A1 (en) 2001-09-12 2003-03-20 Donn Gregory Wishka Substituted 7-aza[2.2.1] bicycloheptanes for the treatment of diseases
JP2005511574A (ja) * 2001-10-26 2005-04-28 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー Ｎａｃｈｒアゴニストとしてのｎ−アザビシクロ−置換ヘテロ二環式カルボキサミド
BR0307874A (pt) * 2002-02-20 2004-12-28 Upjohn Co Atividade de compostos azabicìclicos com receptor de acetilcolina nicotìnica alfa7
WO2004052348A2 (en) 2002-12-11 2004-06-24 Pharmacia & Upjohn Company Llc Treatment of diseases with combinations of alpha 7 nicotinic acetylcholine receptor agonists and other compounds
OA12969A (en) * 2002-12-11 2006-10-13 Pharmacia & Upjohn Co Llc Combination for the treatment of ADHD.
PL378026A1 (pl) * 2003-01-22 2006-02-20 Pharmacia & Upjohn Company Llc Leczenie chorób z zastosowaniem pełnych agonistów receptora Ó-7 nACh

Also Published As

Publication number Publication date
CN100341874C (zh) 2007-10-10
US20070142428A1 (en) 2007-06-21
EP1633752B1 (de) 2010-10-06
BRPI0410233A (pt) 2006-05-09
CN1784404A (zh) 2006-06-07
AU2004235971A1 (en) 2004-11-18
WO2004099206A1 (en) 2004-11-18
CA2524625A1 (en) 2004-11-18
ATE483710T1 (de) 2010-10-15
AU2004235971C1 (en) 2008-12-04
MXPA05012154A (es) 2006-02-08
AU2004235971B2 (en) 2008-04-03
GB0310867D0 (en) 2003-06-18
EP1633752A1 (de) 2006-03-15
US7683075B2 (en) 2010-03-23
JP2006525976A (ja) 2006-11-16

Similar Documents

Publication Publication Date Title
ATE496884T1 (de) Sulphonylaminoessigsaeure derivate und deren verwendung als orexin rezeptor antagoniste
NO20062677L (no) Benzyleteraminforbindelser anvendbare som CCR-5-antagonister
ATE461178T1 (de) Pyridazinyl-piperazine und deren verwendung als histamin-h3-rezeptorliganden
BR0315547A (pt) Derivados de quinolina como antagonistas de crth2
HK1092472A1 (en) Certain substituted spirocyclic lactams and use thereof as pharmaceuticals
UA83659C2 (ru) Антагонисты рецепторов p2x7 и их применение, фармацевтическая композиция на их основе, способ их получения (варианты)
WO2005123731A3 (en) Pyrrolopyridine derivatives and their use as crth2 antagonists
AP2004003184A0 (en) Benzofused heteroaryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same and methods for their use.
HK1113790A1 (en) Selurampanel
TW200745024A (en) Carboxamide derivatives as muscarinic receptor antagonists
MX2007007098A (es) Derivados de pirrol que tienen actividad antagonista del receptor crth2.
SE0301653D0 (sv) Novel compounds
TW200508197A (en) Indolone-acetamide derivatives, processes for preparing them and their uses
EA200702589A1 (ru) 2,6-хинолинильные производные, способы их получения и их применение
TW200745122A (en) New compounds I
EA200702375A1 (ru) Производные мочевины, способы их получения и применения
TW200740781A (en) Novel compounds
DE602005019722D1 (de) Substituierte pyrrolidin-2-one
DE60326263D1 (de) Pyrimidin-sulfonamide und ihre verwendung als endothelin-rezeptor-antagonisten
ATE524463T1 (de) 4-chromenonyl-1,4-dihydropyridincarbonitrile und ihre verwendung
MXPA05004273A (es) Derivados de fenilalquil y piridilalquil piperazina.
WO2007027742A3 (en) SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS
SE0300457D0 (sv) Novel compounds
BR0213574A (pt) Compostos básicos lineares apresentando atividade antagonista do nk-2 e formulações contendo os mesmos
DE602004029462D1 (de) Isochinolin-3-carbonsäureamide und ihre pharmazeutische verwendung