ATE290350T1 - Zusammensetzungen und verfahren mit bezug auf eine auf natürliche weise sekretierte matrix - Google Patents

Zusammensetzungen und verfahren mit bezug auf eine auf natürliche weise sekretierte matrix

Info

Publication number
ATE290350T1
ATE290350T1 AT96921369T AT96921369T ATE290350T1 AT E290350 T1 ATE290350 T1 AT E290350T1 AT 96921369 T AT96921369 T AT 96921369T AT 96921369 T AT96921369 T AT 96921369T AT E290350 T1 ATE290350 T1 AT E290350T1
Authority
AT
Austria
Prior art keywords
extracellular matrix
compositions
framework
matrix material
naturally secreted
Prior art date
Application number
AT96921369T
Other languages
English (en)
Inventor
Gail K Naughton
Original Assignee
Smith & Nephew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew filed Critical Smith & Nephew
Application granted granted Critical
Publication of ATE290350T1 publication Critical patent/ATE290350T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0059—Cosmetic or alloplastic implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A61F2/105—Skin implants, e.g. artificial skin
AT96921369T 1995-06-06 1996-06-06 Zusammensetzungen und verfahren mit bezug auf eine auf natürliche weise sekretierte matrix ATE290350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/470,101 US5830708A (en) 1995-06-06 1995-06-06 Methods for production of a naturally secreted extracellular matrix
PCT/US1996/009482 WO1996039101A1 (en) 1995-06-06 1996-06-06 Compositions and methods for naturally secreted extracellular matrix

Publications (1)

Publication Number Publication Date
ATE290350T1 true ATE290350T1 (de) 2005-03-15

Family

ID=23866272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921369T ATE290350T1 (de) 1995-06-06 1996-06-06 Zusammensetzungen und verfahren mit bezug auf eine auf natürliche weise sekretierte matrix

Country Status (11)

Country Link
US (1) US5830708A (de)
EP (1) EP0967934B1 (de)
JP (1) JP3709487B2 (de)
KR (1) KR19990022216A (de)
AT (1) ATE290350T1 (de)
AU (1) AU708090B2 (de)
CA (1) CA2223892A1 (de)
DE (1) DE69634454T2 (de)
ES (1) ES2238076T3 (de)
NZ (1) NZ311313A (de)
WO (1) WO1996039101A1 (de)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974571B2 (en) * 1995-03-28 2005-12-13 Thomas Jefferson University Isolated stromal cells and methods of using the same
US6284284B1 (en) * 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US7767452B2 (en) 1997-02-20 2010-08-03 Kleinsek Don A Tissue treatments with adipocyte cells
WO1998036705A1 (en) * 1997-02-20 1998-08-27 Keller Gregory S Augmentation and repair of dermal, subcutaneous, and vocal cord tissue defects
US6225118B1 (en) 1997-10-01 2001-05-01 Biocure Limited Multicellular in vitro assay of angiogenesis
GB9720987D0 (en) * 1997-10-01 1997-12-03 Biocure Ltd A multicellular in vitro assay of angiogenesis
US6660301B1 (en) 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
AU3097999A (en) * 1998-03-18 1999-10-11 University Of Pittsburgh Chitosan-based composite materials containing glycosaminoglycan for cartilage repair
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
US6428978B1 (en) 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
ES2249928T3 (es) * 1998-11-19 2006-04-01 Organogenesis Inc. Constructos de tejido manipulado mediante bioingenieria y metodos para producirlos y utilizarlos.
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US6662805B2 (en) 1999-03-24 2003-12-16 The Johns Hopkins University Method for composite cell-based implants
US20030007954A1 (en) 1999-04-12 2003-01-09 Gail K. Naughton Methods for using a three-dimensional stromal tissue to promote angiogenesis
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
EP1196206A1 (de) * 1999-07-09 2002-04-17 Advanced Tissue Sciences, Inc. Mit menschlicher natürlich sekretierter extrazellulärer matrix beschichteter gegenstand
CA2383398C (en) * 1999-08-23 2013-06-11 Organogenesis, Inc. Skin care compositions and treatments
US20080267923A2 (en) * 1999-11-05 2008-10-30 Donald Kleinsek Hair undifferentiated cells
WO2001032129A2 (en) * 1999-11-05 2001-05-10 Gerigene Medical Corporation Augmentation and repair of age-related soft tissue defects
US20090074729A2 (en) * 1999-11-05 2009-03-19 Donald Kleinsek Augmentation and repair of spincter defects with cells including fibroblasts
US7799325B2 (en) * 1999-11-05 2010-09-21 Kleinsek Donald A Removal of hypertrophic scars
US20080286242A2 (en) * 1999-11-05 2008-11-20 Donald Kleinsek Augmentation and repair of spincter defects with cells including mesenchymal cells
EP1259634A4 (de) 2000-03-02 2004-07-07 Univ Rochester Ex vivo erstellung funktioneller leukämiezellen in einem dreidimensionalen bioreaktor
WO2001070290A2 (en) 2000-03-20 2001-09-27 Biosphere Medical, Inc. Injectable microspheres for tissue construction
US6436424B1 (en) * 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
US7338657B2 (en) * 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
EP1274472A2 (de) 2000-03-20 2003-01-15 Biosphere Medical, Inc. Injizierbare und schwellfähige mikrokügelchen zur gewebeverstärkung
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) * 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
WO2002014480A2 (en) * 2000-08-16 2002-02-21 Duke University Decellularized tissue engineered constructs and tissues
MXPA03001914A (es) 2000-09-01 2004-05-24 Univ Virginia Commonwealth Matrices basadas en fibrina electroprocesada y tejidos.
US20090130066A1 (en) * 2000-11-06 2009-05-21 Gerigene Medical Corporation Augmentation and repair of sphincter defects with cells including muscle cells
CA2467359C (en) * 2000-11-17 2010-11-02 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR100915482B1 (ko) 2000-12-06 2009-09-03 하리리 로버트 제이 태반 줄기 세포의 회수 방법
US7041868B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Bioabsorbable wound dressing
EP1362095B1 (de) 2001-02-14 2015-05-27 Anthrogenesis Corporation Post-partum säugetier-plazenta, deren verwendung und daraus gewonnene stammzellen
NZ528035A (en) 2001-02-14 2005-07-29 Robert J Hariri Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
US7361195B2 (en) * 2001-07-16 2008-04-22 Depuy Products, Inc. Cartilage repair apparatus and method
WO2003007790A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
JP4197157B2 (ja) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復再生装置および方法
WO2003007839A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Devices form naturally occurring biologically derived
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
EP2301343A1 (de) 2002-02-13 2011-03-30 Anthrogenesis Corporation Embryoartige Stammzellen aus der Post Partum Plazenta von Säugetieren sowie Anwendungszwecke und Behandlungsverfahren, bei denen diese Zellen verwendet werden
AU2003219830A1 (en) * 2002-02-22 2003-09-09 Ebi, L.P. Methods and compositions for treating bone or cartilage defects
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
KR100527623B1 (ko) * 2002-06-01 2005-11-15 라이프코드인터내셔날 주식회사 세포외기질을 포함하는 인공장기 제조용 생분해성 고분자기질 및 그의 제조방법
EP1571910A4 (de) 2002-11-26 2009-10-28 Anthrogenesis Corp Zytotherapeutika, zytotherapeutischeeinheiten und behandlungsverfahren, bei denen diese verwendet werden
IL156945A0 (en) * 2003-07-15 2004-02-08 Itzhak Tavori Device and a method for orthopedic delivery of bone reconstruction medium
US7326571B2 (en) * 2003-07-17 2008-02-05 Boston Scientific Scimed, Inc. Decellularized bone marrow extracellular matrix
JP2005211099A (ja) * 2004-01-27 2005-08-11 Olympus Corp 人工臓器構成材および人工臓器構成体の製造方法および人工臓器
WO2005110050A2 (en) * 2004-05-11 2005-11-24 Synthasome Inc. Tissue scaffold
US20070190108A1 (en) * 2004-05-17 2007-08-16 Arindam Datta High performance reticulated elastomeric matrix preparation, properties, reinforcement, and use in surgical devices, tissue augmentation and/or tissue repair
AU2005279878A1 (en) * 2004-08-30 2006-03-09 Theregen, Inc. Conditioned medium comprising Wnt proteins to promote repair of damaged tissue
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
JP2008546686A (ja) * 2005-06-17 2008-12-25 セレゲン，インコーポレーテッド 虚血組織の治療方法
US20070065415A1 (en) * 2005-09-16 2007-03-22 Kleinsek Donald A Compositions and methods for the augmentation and repair of defects in tissue
ES2452595T3 (es) 2005-10-13 2014-04-02 Anthrogenesis Corporation Inmunomodulación usando células madre de la placenta
JP5409009B2 (ja) * 2005-12-01 2014-02-05 エイジェンシー フォー サイエンス，テクノロジー アンド リサーチ 組織工学の足場としての三次元再構成細胞外マトリクス
PL2471904T3 (pl) 2005-12-29 2019-08-30 Celularity, Inc. Populacje komórek macierzystych łożyska
US8455250B2 (en) 2005-12-29 2013-06-04 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US20070178137A1 (en) * 2006-02-01 2007-08-02 Toby Freyman Local control of inflammation
CA2850793A1 (en) 2006-10-23 2008-05-02 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
AU2008216749B2 (en) 2007-02-12 2014-03-13 Celularity Inc. Treatment of inflammatory diseases using placental stem cells
EP2129775A1 (de) 2007-02-12 2009-12-09 Anthrogenesis Corporation Hepatocyten und chondrocyten aus adhärenten plazentastammzellen sowie cd34+, cd45- plazentastammzellenangereicherte zellpopulationen
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
EP2783692B1 (de) 2007-09-28 2019-01-02 Celularity, Inc. Tumorsuppression mit menschlichem Plazentaperfusat und menschlichen natürlichen Killerzellen eines Zwischenproduktes aus der Plazenta
MX2010005018A (es) 2007-11-07 2010-05-27 Anthrogenesis Corp Tratamiento de complicaciones de nacimiento prematuro.
PL2247285T3 (pl) 2007-11-30 2014-11-28 Rnl Bio Co Ltd Komórkowy środek terapeutyczny na nietrzymanie moczu zawierający komórki macierzyste pochodzące z doczesnej
WO2009073178A1 (en) 2007-12-03 2009-06-11 Sanbio, Inc. Extracellular matrix from pluripotent cells
KR101650957B1 (ko) 2008-01-30 2016-08-24 히스토젠, 인코포레이티드 세포외 기질 조성물
HUE043642T2 (hu) * 2008-07-02 2019-08-28 Allergan Inc Kompozíció lágy szövet feltöltésére és regenerálására
MX2011001990A (es) 2008-08-20 2011-03-29 Anthrogenesis Corp Composiciones mejoradas de celulas y metodos para preparar las mismas.
CN102497871B (zh) 2008-11-14 2014-10-15 希斯托金公司 用于癌症治疗的胞外基质组合物
KR20110086176A (ko) 2008-11-19 2011-07-27 안트로제네시스 코포레이션 양막 유래 부착성 세포
CN102482698B (zh) 2009-07-10 2018-09-25 希斯托金公司 条件培养基和来自低氧含量条件下培养的细胞的胞外基质组合物
ES2673726T3 (es) 2010-01-05 2018-06-25 Cell Constructs I, Llc Biomateriales fabricados a partir de cabello humano
ES2646750T3 (es) 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
SI2556145T1 (sl) 2010-04-07 2017-01-31 Anthrogenesis Corporation Angiogeneza z uporabo placentnih matičnih celic
NZ605505A (en) 2010-07-13 2015-02-27 Anthrogenesis Corp Methods of generating natural killer cells
EP2637641B1 (de) 2010-11-12 2019-02-20 Allergan, Inc. Verstoffwechseltes konditioniertes wachstumsmedium und verwendungsverfahren dafür
WO2012092458A2 (en) 2010-12-30 2012-07-05 Anthrogenesis Corporation Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof
US20120171180A1 (en) 2010-12-30 2012-07-05 Sascha Abramson Compositions comprising amnion derived adherent cells and platelet-rich plasma
AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
EP3011936B8 (de) 2011-01-06 2019-07-24 Humacyte, Inc. Gewebegezüchtete konstrukte
EP3443968A1 (de) 2011-06-01 2019-02-20 Celularity, Inc. Schmerzbehandlung mithilfe von stammzellen aus der plazenta
US10501791B2 (en) 2011-10-14 2019-12-10 President And Fellows Of Harvard College Sequencing by structure assembly
ES2953308T3 (es) 2011-12-22 2023-11-10 Harvard College Composiciones y métodos para la detección de analitos
US11021737B2 (en) 2011-12-22 2021-06-01 President And Fellows Of Harvard College Compositions and methods for analyte detection
WO2013168117A2 (en) * 2012-05-09 2013-11-14 Koninklijke Philips N.V. Interventional information brokering medical tracking interface
WO2013184754A2 (en) 2012-06-05 2013-12-12 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using dna origami probes
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
US10138509B2 (en) 2013-03-12 2018-11-27 President And Fellows Of Harvard College Method for generating a three-dimensional nucleic acid containing matrix
JP6882282B2 (ja) 2015-11-03 2021-06-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 三次元核酸含有マトリックスの立体撮像のための方法と装置
CN109415761B (zh) 2016-04-25 2022-09-20 哈佛学院董事及会员团体 用于原位分子检测的杂交链反应方法
CN105920679B (zh) * 2016-04-26 2018-10-19 青岛大学 一种具有三维梯度孔结构的皮肤支架材料的制备方法
CN109923216A (zh) 2016-08-31 2019-06-21 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
CN109983125A (zh) 2016-08-31 2019-07-05 哈佛学院董事及会员团体 生成用于通过荧光原位测序检测的核酸序列文库的方法
US11185568B2 (en) 2017-04-14 2021-11-30 President And Fellows Of Harvard College Methods for generation of cell-derived microfilament network
US11718829B2 (en) 2017-07-28 2023-08-08 Breakthrough Tech Llc Methods and compositions for manufacturing extracellular matrix
CN112770776A (zh) 2018-07-30 2021-05-07 瑞德库尔有限责任公司 用于样品处理或分析的方法和系统
CN111084788A (zh) * 2018-10-22 2020-05-01 上海蓝盎电子科技发展有限公司 人工细胞间质
CN115006597B (zh) * 2022-06-02 2024-01-19 上海威高医疗技术发展有限公司 一种口腔修复膜及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US5288617A (en) * 1984-10-31 1994-02-22 Commonwealth Scientific And Industrial Research Organization Method of producing an antigenic preparation
US5460939A (en) * 1986-04-18 1995-10-24 Advanced Tissue Sciences, Inc. Temporary living skin replacement
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4721096A (en) * 1986-04-18 1988-01-26 Marrow-Tech Incorporated Process for replicating bone marrow in vitro and using the same
US5160490A (en) * 1986-04-18 1992-11-03 Marrow-Tech Incorporated Three-dimensional cell and tissue culture apparatus
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
JPH041118Y2 (de) * 1986-07-31 1992-01-14
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5342765A (en) * 1991-08-01 1994-08-30 Occidental Chemical Corporation Method of producing extracellular products from aerobic microorganisms
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5541106A (en) * 1993-04-05 1996-07-30 Desmos, Inc. Cell matrix stimulated attachment and hemidesmosome assembly
US5397352A (en) * 1993-08-27 1995-03-14 Burres; Steven Method of recollagenation
US5516532A (en) * 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation

Also Published As

Publication number Publication date
DE69634454T2 (de) 2006-05-11
US5830708A (en) 1998-11-03
EP0967934A4 (de) 2001-11-28
KR19990022216A (ko) 1999-03-25
DE69634454D1 (de) 2005-04-14
JP3709487B2 (ja) 2005-10-26
JPH11507558A (ja) 1999-07-06
NZ311313A (en) 2000-05-26
EP0967934B1 (de) 2005-03-09
ES2238076T3 (es) 2005-08-16
EP0967934A1 (de) 2000-01-05
WO1996039101A1 (en) 1996-12-12
AU708090B2 (en) 1999-07-29
CA2223892A1 (en) 1996-12-12
AU6260996A (en) 1996-12-24

Similar Documents

Publication Publication Date Title
ATE290350T1 (de) Zusammensetzungen und verfahren mit bezug auf eine auf natürliche weise sekretierte matrix
Chevallay et al. Mouse fibroblasts in long‐term culture within collagen three‐dimensional scaffolds: influence of crosslinking with diphenylphosphorylazide on matrix reorganization, growth, and biosynthetic and proteolytic activities
DE69630129T2 (de) Gebrauch von autologen, dermalen fibroblasten zur reperatur von haut- oder weichgewebeschäden
US5639654A (en) Process for creating a skin substitute and the resulting skin substitute
DE69927600T2 (de) Biotechnisch konstruiertes gewebe und verfahren zu dessen produktion und benutzung
WO2001032129A3 (en) Augmentation and repair of age-related soft tissue defects
Pirayesh et al. Glyaderm® dermal substitute: clinical application and long-term results in 55 patients
HUT60514A (en) Process for producing biocompatible perforated membranes and their application for promoting in vitro growth of cells of epithelial tissue
US20080311089A1 (en) Augmentation and Repair of Vocal Cord Tissue Defects
WO1996039101B1 (en) Compositions and methods for naturally secreted extracellular matrix
Kinikoglu et al. Reconstruction of a full-thickness collagen-based human oral mucosal equivalent
Repesh et al. Ultrastructural studies on migrating epidermal cells during the wound healing stage of regeneration in the adult newt, Notophthalmus viridescens
EP1792980B1 (de) Kollagenbiomatrix und Verfahren zu ihrer Herstellung
Mol et al. Grafting of venous leg ulcers: an intraindividual comparison between cultured skin equivalents and full-thickness skin punch grafts
CN109550080A (zh) 一种人工双层皮肤及其制备方法
Ophof et al. Oral keratinocytes cultured on dermal matrices form a mucosa-like tissue
Naughton et al. Emerging developments in tissue engineering and cell technology
Benali et al. Tubule formation by human surface respiratory epithelial cells cultured in a three-dimensional collagen lattice
CA2281758A1 (en) Repair of autologous tissue defects
JP2005305177A (ja) 組織付属器官様構造体を含む人工組織およびその製造方法
Pajoum et al. In vitro co-culture of human skin keratinocytes and fibroblasts on a biocompatible and biodegradable scaffold
Meinke A light and scanning electron microscope study of microstructure, growth and development of the dermal skeleton of Polypterus (Pisces: Actinopterygii)
Lengelé et al. Embryonic origin and fate of chondroid tissue and secondary cartilages in the avian skull
JPH10136977A (ja) 組織付属器官様構造体を含む人工組織およびその製造方法
Goulet et al. Tissue-engineered ligament

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties