ATE259377T1 - An den zelloberflächenrezeptor hek bindendes cytokin - Google Patents

An den zelloberflächenrezeptor hek bindendes cytokin

Info

Publication number
ATE259377T1
ATE259377T1 AT94925915T AT94925915T ATE259377T1 AT E259377 T1 ATE259377 T1 AT E259377T1 AT 94925915 T AT94925915 T AT 94925915T AT 94925915 T AT94925915 T AT 94925915T AT E259377 T1 ATE259377 T1 AT E259377T1
Authority
AT
Austria
Prior art keywords
hek
polypeptides
cell surface
surface receptor
cytokine binding
Prior art date
Application number
AT94925915T
Other languages
English (en)
Inventor
M Patricia Beckmann
Douglas P Cerretti
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE259377T1 publication Critical patent/ATE259377T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
AT94925915T 1993-08-20 1994-08-17 An den zelloberflächenrezeptor hek bindendes cytokin ATE259377T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10974593A 1993-08-20 1993-08-20
US11442693A 1993-08-30 1993-08-30
US16113293A 1993-12-03 1993-12-03
US08/240,124 US5516658A (en) 1993-08-20 1994-05-09 DNA encoding cytokines that bind the cell surface receptor hek
PCT/US1994/009282 WO1995006065A1 (en) 1993-08-20 1994-08-17 Cytokines that bind the cell surface receptor hek

Publications (1)

Publication Number Publication Date
ATE259377T1 true ATE259377T1 (de) 2004-02-15

Family

ID=27493708

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925915T ATE259377T1 (de) 1993-08-20 1994-08-17 An den zelloberflächenrezeptor hek bindendes cytokin

Country Status (15)

Country Link
US (5) US5516658A (de)
EP (1) EP0804482B1 (de)
JP (2) JP3699477B2 (de)
KR (1) KR960704038A (de)
AT (1) ATE259377T1 (de)
AU (1) AU680540B2 (de)
CA (1) CA2169851A1 (de)
DE (1) DE69433552T2 (de)
DK (1) DK0804482T3 (de)
ES (1) ES2216000T3 (de)
FI (1) FI960743A (de)
NO (1) NO960652D0 (de)
NZ (1) NZ271878A (de)
PT (1) PT804482E (de)
WO (1) WO1995006065A1 (de)

Families Citing this family (98)

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US5516658A (en) * 1993-08-20 1996-05-14 Immunex Corporation DNA encoding cytokines that bind the cell surface receptor hek
EP0758381B2 (de) * 1994-04-04 2006-11-15 Regeneron Pharmaceuticals, Inc. Biologisch aktive ligande der eph familie
US6303769B1 (en) 1994-07-08 2001-10-16 Immunex Corporation Lerk-5 dna
KR970705923A (ko) 1994-10-05 1997-11-03 크리스토퍼 엘. 와이트 LERK-6으로 명명된 시토킨(Cytokine Designated LERK-6)
US5919905A (en) * 1994-10-05 1999-07-06 Immunex Corporation Cytokine designated LERK-6
USRE37582E1 (en) 1994-10-05 2002-03-12 Immunex Corporation Cytokine designated LERK-6
WO1998001548A1 (en) * 1996-07-05 1998-01-15 Mount Sinai Hospital Corporation Oligomerized receptors which affect pathways regulated by transmembrane ligands for elk-related receptor tyrosine kinases
US6448035B1 (en) 1997-04-24 2002-09-10 Immunex Corporation Family of immunoregulators designated leukocyte immunoglobulin-like receptor (LIR)
US6384203B1 (en) 1999-05-12 2002-05-07 Immunex Corporation Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
AUPO754997A0 (en) * 1997-06-25 1997-07-17 Leukaemia Foundation Of Queensland, The Receptor-ligand system and assay therefor
US20030198951A1 (en) * 1999-12-02 2003-10-23 David Mack Novel methods of diagnosing colorectal cancer and/or breast cancer, compositions, and methods of screening for colorectal cancer and/or breast cancer modulators
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Also Published As

Publication number Publication date
US5738844A (en) 1998-04-14
DK0804482T3 (da) 2004-06-07
AU7567594A (en) 1995-03-21
EP0804482A1 (de) 1997-11-05
NO960652L (no) 1996-02-19
NZ271878A (en) 1997-10-24
JP3786944B2 (ja) 2006-06-21
US5516658A (en) 1996-05-14
JP2004187689A (ja) 2004-07-08
NO960652D0 (no) 1996-02-19
KR960704038A (ko) 1996-08-31
EP0804482B1 (de) 2004-02-11
CA2169851A1 (en) 1995-03-02
FI960743A0 (fi) 1996-02-19
ES2216000T3 (es) 2004-10-16
JPH09502174A (ja) 1997-03-04
US6949366B2 (en) 2005-09-27
US5969110A (en) 1999-10-19
EP0804482A4 (de) 2001-05-16
FI960743A (fi) 1996-02-19
AU680540B2 (en) 1997-07-31
JP3699477B2 (ja) 2005-09-28
DE69433552D1 (de) 2004-03-18
US6274117B1 (en) 2001-08-14
PT804482E (pt) 2004-06-30
DE69433552T2 (de) 2004-12-16
WO1995006065A1 (en) 1995-03-02
US20020010325A1 (en) 2002-01-24

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