ATE241981T1 - Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks - Google Patents

Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks

Info

Publication number
ATE241981T1
ATE241981T1 AT94902578T AT94902578T ATE241981T1 AT E241981 T1 ATE241981 T1 AT E241981T1 AT 94902578 T AT94902578 T AT 94902578T AT 94902578 T AT94902578 T AT 94902578T AT E241981 T1 ATE241981 T1 AT E241981T1
Authority
AT
Austria
Prior art keywords
aminopyridine
spinal cord
spastic
resulting
cord injury
Prior art date
Application number
AT94902578T
Other languages
English (en)
Inventor
Robert R Hansebout
Andrew R Blight
Original Assignee
Canadian Spinal Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canadian Spinal Res Org filed Critical Canadian Spinal Res Org
Application granted granted Critical
Publication of ATE241981T1 publication Critical patent/ATE241981T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT94902578T 1992-12-18 1993-12-20 Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks ATE241981T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002085785A CA2085785C (en) 1992-12-18 1992-12-18 The use of 4-aminopyridine in the treatment of a neurological condition
PCT/CA1993/000554 WO1994014439A1 (en) 1992-12-18 1993-12-20 The use of 4-aminopyridine in the treatment of a neurological condition

Publications (1)

Publication Number Publication Date
ATE241981T1 true ATE241981T1 (de) 2003-06-15

Family

ID=4150879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94902578T ATE241981T1 (de) 1992-12-18 1993-12-20 Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks

Country Status (19)

Country Link
US (1) US5545648A (de)
EP (1) EP0626848B1 (de)
JP (1) JP3474569B2 (de)
KR (1) KR100301415B1 (de)
AT (1) ATE241981T1 (de)
AU (1) AU676251B2 (de)
BG (1) BG62272B1 (de)
BR (1) BR9305909A (de)
CA (1) CA2085785C (de)
CZ (1) CZ284441B6 (de)
DE (1) DE69333014T2 (de)
ES (1) ES2199957T3 (de)
FI (1) FI943765A (de)
HU (1) HU219583B (de)
NO (2) NO308644B1 (de)
NZ (1) NZ258844A (de)
RU (1) RU2160590C2 (de)
SK (1) SK280922B6 (de)
WO (1) WO1994014439A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792743A (en) * 1995-04-19 1998-08-11 Acorda Therapeutics Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
US6190370B1 (en) 1997-07-25 2001-02-20 Arrow International, Inc. Devices, systems and methods for determining proper placement of epidural catheters
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
CA2360326C (en) * 1999-02-09 2011-04-05 Uab Research Foundation Use of 4-amino pyridine for treatment of peripheral neuropathies
NO324322B1 (no) 2001-02-26 2007-09-24 Dynea Oy Anvendelse av herder samt fremgangsmate ved liming
JP2004527573A (ja) 2001-04-24 2004-09-09 パーデュー・リサーチ・ファウンデーション 哺乳類の神経組織損傷の治療のための方法及び組成物
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
AU2003298034B2 (en) * 2002-12-06 2011-04-21 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
JP4533590B2 (ja) * 2003-02-28 2010-09-01 ファイザー株式会社 脊髄損傷患者における疼痛又は痙性軽減用医薬組成物
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
BR112013019265A2 (pt) * 2011-01-28 2016-10-11 Acorda Therapeutics Inc uso de bloqueadores do canal de potássio no tratamento da paralisia cerebral
US8924325B1 (en) * 2011-02-08 2014-12-30 Lockheed Martin Corporation Computerized target hostility determination and countermeasure
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508715A (en) * 1981-07-01 1985-04-02 University Of Georgia Research Foundation, Inc. Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs
JPH03505868A (ja) * 1988-04-08 1991-12-19 マサチユセツツ・インスチチユート・オブ・テクノロジー 神経性疾患を治療するための方法及び組成物
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases

Also Published As

Publication number Publication date
BR9305909A (pt) 1997-10-21
US5545648A (en) 1996-08-13
BG62272B1 (bg) 1999-07-30
DE69333014T2 (de) 2004-05-06
HU9402647D0 (en) 1994-11-28
JP3474569B2 (ja) 2003-12-08
NO2012003I1 (no) 2012-02-13
EP0626848A1 (de) 1994-12-07
NO943049L (no) 1994-10-17
EP0626848B1 (de) 2003-06-04
NZ258844A (en) 1997-04-24
RU94041207A (ru) 1996-06-20
CZ225494A3 (en) 1995-03-15
JPH08504772A (ja) 1996-05-21
NO308644B1 (no) 2000-10-09
SK96994A3 (en) 1995-04-12
ES2199957T3 (es) 2004-03-01
HU219583B (hu) 2001-05-28
FI943765A (fi) 1994-10-14
AU676251B2 (en) 1997-03-06
KR950700062A (ko) 1995-01-16
SK280922B6 (sk) 2000-09-12
CZ284441B6 (cs) 1998-11-11
CA2085785C (en) 2005-03-15
CA2085785A1 (en) 1994-06-19
NO943049D0 (no) 1994-08-17
RU2160590C2 (ru) 2000-12-20
HUT68171A (en) 1995-05-29
FI943765A0 (fi) 1994-08-16
KR100301415B1 (ko) 2001-11-22
DE69333014D1 (de) 2003-07-10
WO1994014439A1 (en) 1994-07-07
NO2012003I2 (no) 2013-02-18
BG99047A (bg) 1995-06-30
AU5691194A (en) 1994-07-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties