RU94041207A - Средство для лечения заболеваний, поражающих нервную систему - Google Patents
Средство для лечения заболеваний, поражающих нервную системуInfo
- Publication number
- RU94041207A RU94041207A RU94041207/14A RU94041207A RU94041207A RU 94041207 A RU94041207 A RU 94041207A RU 94041207/14 A RU94041207/14 A RU 94041207/14A RU 94041207 A RU94041207 A RU 94041207A RU 94041207 A RU94041207 A RU 94041207A
- Authority
- RU
- Russia
- Prior art keywords
- spinal cord
- aminopyridine
- remedy
- patients
- nervous system
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Описывается использование 4-аминопиридина в лечении нейрологического заболевания. В частности данное изобретение касается использования 4-аминопиридина для лечения пациентов с поврежденным спинным мозгом. Было найдено, что 4-аминопиридин может снижать боль и спастичность у больных с повреждением спинного мозга при введении его в дозах примерно от 18 до 30 мг внутривенно. Результаты довольно существенны ввиду высокой частоты данных проблем и трудно устранимого характера боли при повреждении спинного мозга. Кроме того, 4-аминопиридин используется для повышения сенсорной способности и двигательной регуляции.
Claims (1)
- Описывается использование 4-аминопиридина в лечении нейрологического заболевания. В частности данное изобретение касается использования 4-аминопиридина для лечения пациентов с поврежденным спинным мозгом. Было найдено, что 4-аминопиридин может снижать боль и спастичность у больных с повреждением спинного мозга при введении его в дозах примерно от 18 до 30 мг внутривенно. Результаты довольно существенны ввиду высокой частоты данных проблем и трудно устранимого характера боли при повреждении спинного мозга. Кроме того, 4-аминопиридин используется для повышения сенсорной способности и двигательной регуляции.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002085785A CA2085785C (en) | 1992-12-18 | 1992-12-18 | The use of 4-aminopyridine in the treatment of a neurological condition |
| CA2.085,785 | 1992-12-18 | ||
| CA2085785 | 1992-12-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU94041207A true RU94041207A (ru) | 1996-06-20 |
| RU2160590C2 RU2160590C2 (ru) | 2000-12-20 |
Family
ID=4150879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU94041207/14A RU2160590C2 (ru) | 1992-12-18 | 1993-12-20 | Способ лечения боли и спастичности |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5545648A (ru) |
| EP (1) | EP0626848B1 (ru) |
| JP (1) | JP3474569B2 (ru) |
| KR (1) | KR100301415B1 (ru) |
| AT (1) | ATE241981T1 (ru) |
| AU (1) | AU676251B2 (ru) |
| BG (1) | BG62272B1 (ru) |
| BR (1) | BR9305909A (ru) |
| CA (1) | CA2085785C (ru) |
| CZ (1) | CZ284441B6 (ru) |
| DE (1) | DE69333014T2 (ru) |
| ES (1) | ES2199957T3 (ru) |
| FI (1) | FI943765A (ru) |
| HU (1) | HU219583B (ru) |
| NO (2) | NO308644B1 (ru) |
| NZ (1) | NZ258844A (ru) |
| RU (1) | RU2160590C2 (ru) |
| SK (1) | SK280922B6 (ru) |
| WO (1) | WO1994014439A1 (ru) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792743A (en) * | 1995-04-19 | 1998-08-11 | Acorda Therapeutics | Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule |
| JPH09315972A (ja) * | 1996-03-22 | 1997-12-09 | Chugai Pharmaceut Co Ltd | 脊髄損傷治療剤 |
| WO1999004705A1 (en) | 1997-07-25 | 1999-02-04 | Tsui Ban C H | Devices, systems and methods for determining proper placement of epidural catheters |
| US7582680B1 (en) | 1998-11-12 | 2009-09-01 | Purdue Research Foundation | Methods and compositions for treating mammalian spinal cord injuries |
| WO2000047210A1 (en) * | 1999-02-09 | 2000-08-17 | Uab Research Foundation | Use of 4-amino pyridine for treatment of peripheral neuropathies |
| NO324322B1 (no) | 2001-02-26 | 2007-09-24 | Dynea Oy | Anvendelse av herder samt fremgangsmate ved liming |
| CA2445612C (en) | 2001-04-24 | 2011-10-25 | Purdue Research Foundation | Methods and compositions for treating mammalian nerve tissue injuries |
| US20040047843A1 (en) * | 2002-02-12 | 2004-03-11 | Uab Research Foundation | Method for spinal cord reconnection |
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| WO2004052291A2 (en) * | 2002-12-06 | 2004-06-24 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| JP4533590B2 (ja) * | 2003-02-28 | 2010-09-01 | ファイザー株式会社 | 脊髄損傷患者における疼痛又は痙性軽減用医薬組成物 |
| US20050192321A1 (en) * | 2003-09-15 | 2005-09-01 | Meythaler Jay M. | Treatment of neuropathy with rapid release aminopyridine |
| US8007826B2 (en) * | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
| US8354437B2 (en) | 2004-04-09 | 2013-01-15 | Acorda Therapeutics, Inc. | Method of using sustained release aminopyridine compositions |
| US20130030025A1 (en) * | 2011-01-28 | 2013-01-31 | Wessel Thomas C | Use of potassium channel blockers to treat cerebral palsy |
| US8924325B1 (en) * | 2011-02-08 | 2014-12-30 | Lockheed Martin Corporation | Computerized target hostility determination and countermeasure |
| TWI592156B (zh) * | 2011-10-04 | 2017-07-21 | 艾可達醫療公司 | 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4508715A (en) * | 1981-07-01 | 1985-04-02 | University Of Georgia Research Foundation, Inc. | Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs |
| WO1989009600A1 (en) * | 1988-04-08 | 1989-10-19 | Massachusetts Institute Of Technology | Method and composition for treating neurological disorders |
| IE82916B1 (en) * | 1990-11-02 | 2003-06-11 | Elan Corp Plc | Formulations and their use in the treatment of neurological diseases |
-
1992
- 1992-12-18 CA CA002085785A patent/CA2085785C/en not_active Expired - Lifetime
-
1993
- 1993-12-20 JP JP51463794A patent/JP3474569B2/ja not_active Expired - Lifetime
- 1993-12-20 NZ NZ258844A patent/NZ258844A/en not_active IP Right Cessation
- 1993-12-20 AT AT94902578T patent/ATE241981T1/de not_active IP Right Cessation
- 1993-12-20 SK SK969-94A patent/SK280922B6/sk not_active IP Right Cessation
- 1993-12-20 CZ CZ942254A patent/CZ284441B6/cs not_active IP Right Cessation
- 1993-12-20 HU HU9402647A patent/HU219583B/hu unknown
- 1993-12-20 KR KR1019940702838A patent/KR100301415B1/ko not_active IP Right Cessation
- 1993-12-20 ES ES94902578T patent/ES2199957T3/es not_active Expired - Lifetime
- 1993-12-20 WO PCT/CA1993/000554 patent/WO1994014439A1/en active IP Right Grant
- 1993-12-20 DE DE69333014T patent/DE69333014T2/de not_active Expired - Lifetime
- 1993-12-20 BR BR9305909A patent/BR9305909A/pt not_active Application Discontinuation
- 1993-12-20 AU AU56911/94A patent/AU676251B2/en not_active Expired
- 1993-12-20 US US08/290,757 patent/US5545648A/en not_active Expired - Lifetime
- 1993-12-20 RU RU94041207/14A patent/RU2160590C2/ru active
- 1993-12-20 EP EP94902578A patent/EP0626848B1/en not_active Expired - Lifetime
-
1994
- 1994-08-16 FI FI943765A patent/FI943765A/fi unknown
- 1994-08-17 NO NO943049A patent/NO308644B1/no not_active IP Right Cessation
- 1994-09-16 BG BG99047A patent/BG62272B1/bg unknown
-
2012
- 2012-01-30 NO NO2012003C patent/NO2012003I2/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9305909A (pt) | 1997-10-21 |
| EP0626848B1 (en) | 2003-06-04 |
| AU5691194A (en) | 1994-07-19 |
| ES2199957T3 (es) | 2004-03-01 |
| HUT68171A (en) | 1995-05-29 |
| NO308644B1 (no) | 2000-10-09 |
| FI943765A (fi) | 1994-10-14 |
| US5545648A (en) | 1996-08-13 |
| ATE241981T1 (de) | 2003-06-15 |
| CA2085785C (en) | 2005-03-15 |
| DE69333014T2 (de) | 2004-05-06 |
| NZ258844A (en) | 1997-04-24 |
| NO943049L (no) | 1994-10-17 |
| JPH08504772A (ja) | 1996-05-21 |
| NO2012003I2 (no) | 2013-02-18 |
| WO1994014439A1 (en) | 1994-07-07 |
| KR100301415B1 (ko) | 2001-11-22 |
| EP0626848A1 (en) | 1994-12-07 |
| NO943049D0 (no) | 1994-08-17 |
| HU9402647D0 (en) | 1994-11-28 |
| RU2160590C2 (ru) | 2000-12-20 |
| SK280922B6 (sk) | 2000-09-12 |
| CZ225494A3 (en) | 1995-03-15 |
| AU676251B2 (en) | 1997-03-06 |
| BG99047A (bg) | 1995-06-30 |
| BG62272B1 (bg) | 1999-07-30 |
| KR950700062A (ko) | 1995-01-16 |
| DE69333014D1 (de) | 2003-07-10 |
| SK96994A3 (en) | 1995-04-12 |
| CA2085785A1 (en) | 1994-06-19 |
| JP3474569B2 (ja) | 2003-12-08 |
| FI943765A0 (fi) | 1994-08-16 |
| HU219583B (hu) | 2001-05-28 |
| NO2012003I1 (no) | 2012-02-13 |
| CZ284441B6 (cs) | 1998-11-11 |
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