DE69333014D1 - Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks - Google Patents

Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks

Info

Publication number
DE69333014D1
DE69333014D1 DE69333014T DE69333014T DE69333014D1 DE 69333014 D1 DE69333014 D1 DE 69333014D1 DE 69333014 T DE69333014 T DE 69333014T DE 69333014 T DE69333014 T DE 69333014T DE 69333014 D1 DE69333014 D1 DE 69333014D1
Authority
DE
Germany
Prior art keywords
aminopyridine
pct
pain
backmark
spastic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333014T
Other languages
English (en)
Other versions
DE69333014T2 (de
Inventor
Robert R Hansebout
Andrew R Blight
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canadian Spinal Research Organization
Original Assignee
Canadian Spinal Research Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canadian Spinal Research Organization filed Critical Canadian Spinal Research Organization
Application granted granted Critical
Publication of DE69333014D1 publication Critical patent/DE69333014D1/de
Publication of DE69333014T2 publication Critical patent/DE69333014T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE69333014T 1992-12-18 1993-12-20 Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks Expired - Lifetime DE69333014T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002085785A CA2085785C (en) 1992-12-18 1992-12-18 The use of 4-aminopyridine in the treatment of a neurological condition
CA2085785 1992-12-18
PCT/CA1993/000554 WO1994014439A1 (en) 1992-12-18 1993-12-20 The use of 4-aminopyridine in the treatment of a neurological condition

Publications (2)

Publication Number Publication Date
DE69333014D1 true DE69333014D1 (de) 2003-07-10
DE69333014T2 DE69333014T2 (de) 2004-05-06

Family

ID=4150879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333014T Expired - Lifetime DE69333014T2 (de) 1992-12-18 1993-12-20 Verwendung von 4-aminopyridin zur behandlung von schmerz und spastik folgende einer verletzung des rückenmarks

Country Status (19)

Country Link
US (1) US5545648A (de)
EP (1) EP0626848B1 (de)
JP (1) JP3474569B2 (de)
KR (1) KR100301415B1 (de)
AT (1) ATE241981T1 (de)
AU (1) AU676251B2 (de)
BG (1) BG62272B1 (de)
BR (1) BR9305909A (de)
CA (1) CA2085785C (de)
CZ (1) CZ284441B6 (de)
DE (1) DE69333014T2 (de)
ES (1) ES2199957T3 (de)
FI (1) FI943765A (de)
HU (1) HU219583B (de)
NO (2) NO308644B1 (de)
NZ (1) NZ258844A (de)
RU (1) RU2160590C2 (de)
SK (1) SK280922B6 (de)
WO (1) WO1994014439A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792743A (en) * 1995-04-19 1998-08-11 Acorda Therapeutics Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
WO1999004705A1 (en) 1997-07-25 1999-02-04 Tsui Ban C H Devices, systems and methods for determining proper placement of epidural catheters
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
US6503931B1 (en) * 1999-02-09 2003-01-07 The Uab Research Foundation Use of 4-amino pyridine for treatment of peripheral neuropathies
NO324322B1 (no) 2001-02-26 2007-09-24 Dynea Oy Anvendelse av herder samt fremgangsmate ved liming
AU2002314758B2 (en) 2001-04-24 2006-06-01 Purdue Research Foundation Method and composition for treating mammalian nerve tissue injuries
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
EP1567497B1 (de) * 2002-12-06 2009-09-23 Purdue Research Foundation Pyridine zur behandlung von verletztemsäugetiernervengewebe
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
JP4533590B2 (ja) * 2003-02-28 2010-09-01 ファイザー株式会社 脊髄損傷患者における疼痛又は痙性軽減用医薬組成物
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
BR112013019265A2 (pt) * 2011-01-28 2016-10-11 Acorda Therapeutics Inc uso de bloqueadores do canal de potássio no tratamento da paralisia cerebral
US8924325B1 (en) * 2011-02-08 2014-12-30 Lockheed Martin Corporation Computerized target hostility determination and countermeasure
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508715A (en) * 1981-07-01 1985-04-02 University Of Georgia Research Foundation, Inc. Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs
EP0408650A1 (de) * 1988-04-08 1991-01-23 Massachusetts Institute Of Technology Verfahren und zusammensetzung für die behandlung neurologischer störungen
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases

Also Published As

Publication number Publication date
EP0626848A1 (de) 1994-12-07
SK96994A3 (en) 1995-04-12
FI943765A0 (fi) 1994-08-16
DE69333014T2 (de) 2004-05-06
RU94041207A (ru) 1996-06-20
US5545648A (en) 1996-08-13
SK280922B6 (sk) 2000-09-12
BG99047A (bg) 1995-06-30
HU219583B (hu) 2001-05-28
JP3474569B2 (ja) 2003-12-08
FI943765A (fi) 1994-10-14
HUT68171A (en) 1995-05-29
KR950700062A (ko) 1995-01-16
AU5691194A (en) 1994-07-19
AU676251B2 (en) 1997-03-06
NO943049L (no) 1994-10-17
BR9305909A (pt) 1997-10-21
RU2160590C2 (ru) 2000-12-20
NZ258844A (en) 1997-04-24
NO2012003I1 (no) 2012-02-13
WO1994014439A1 (en) 1994-07-07
NO308644B1 (no) 2000-10-09
BG62272B1 (bg) 1999-07-30
CZ284441B6 (cs) 1998-11-11
CA2085785A1 (en) 1994-06-19
NO943049D0 (no) 1994-08-17
CZ225494A3 (en) 1995-03-15
JPH08504772A (ja) 1996-05-21
HU9402647D0 (en) 1994-11-28
KR100301415B1 (ko) 2001-11-22
NO2012003I2 (no) 2013-02-18
ES2199957T3 (es) 2004-03-01
ATE241981T1 (de) 2003-06-15
CA2085785C (en) 2005-03-15
EP0626848B1 (de) 2003-06-04

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Legal Events

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8364 No opposition during term of opposition