SK280922B6 - Použitie 4-aminopyridínu na prípravu liečiva na zníženie bolesti a spasticity - Google Patents

Použitie 4-aminopyridínu na prípravu liečiva na zníženie bolesti a spasticity Download PDF

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Publication number
SK280922B6
SK280922B6 SK969-94A SK96994A SK280922B6 SK 280922 B6 SK280922 B6 SK 280922B6 SK 96994 A SK96994 A SK 96994A SK 280922 B6 SK280922 B6 SK 280922B6
Authority
SK
Slovakia
Prior art keywords
patients
infusion
aminopyridine
spasticity
effects
Prior art date
Application number
SK969-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK96994A3 (en
Inventor
Robert R. Hansebout
Andrew R. Blight
Original Assignee
Canadian Spinal Research Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canadian Spinal Research Organization filed Critical Canadian Spinal Research Organization
Publication of SK96994A3 publication Critical patent/SK96994A3/sk
Publication of SK280922B6 publication Critical patent/SK280922B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
SK969-94A 1992-12-18 1993-12-20 Použitie 4-aminopyridínu na prípravu liečiva na zníženie bolesti a spasticity SK280922B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002085785A CA2085785C (en) 1992-12-18 1992-12-18 The use of 4-aminopyridine in the treatment of a neurological condition
PCT/CA1993/000554 WO1994014439A1 (en) 1992-12-18 1993-12-20 The use of 4-aminopyridine in the treatment of a neurological condition

Publications (2)

Publication Number Publication Date
SK96994A3 SK96994A3 (en) 1995-04-12
SK280922B6 true SK280922B6 (sk) 2000-09-12

Family

ID=4150879

Family Applications (1)

Application Number Title Priority Date Filing Date
SK969-94A SK280922B6 (sk) 1992-12-18 1993-12-20 Použitie 4-aminopyridínu na prípravu liečiva na zníženie bolesti a spasticity

Country Status (19)

Country Link
US (1) US5545648A (de)
EP (1) EP0626848B1 (de)
JP (1) JP3474569B2 (de)
KR (1) KR100301415B1 (de)
AT (1) ATE241981T1 (de)
AU (1) AU676251B2 (de)
BG (1) BG62272B1 (de)
BR (1) BR9305909A (de)
CA (1) CA2085785C (de)
CZ (1) CZ284441B6 (de)
DE (1) DE69333014T2 (de)
ES (1) ES2199957T3 (de)
FI (1) FI943765A (de)
HU (1) HU219583B (de)
NO (2) NO308644B1 (de)
NZ (1) NZ258844A (de)
RU (1) RU2160590C2 (de)
SK (1) SK280922B6 (de)
WO (1) WO1994014439A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792743A (en) * 1995-04-19 1998-08-11 Acorda Therapeutics Method for promoting neural growth comprising administering a soluble neural cell adhesion molecule
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
US6190370B1 (en) 1997-07-25 2001-02-20 Arrow International, Inc. Devices, systems and methods for determining proper placement of epidural catheters
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
DK1152760T3 (da) * 1999-02-09 2007-07-30 Uab Research Foundation Anvendelse af 4-aminopyridin til behandling af perifere neuropatier
NO324322B1 (no) 2001-02-26 2007-09-24 Dynea Oy Anvendelse av herder samt fremgangsmate ved liming
WO2002092107A1 (en) * 2001-04-24 2002-11-21 Purdue Research Foundation Method and compositions for treating mammalian nerve tissue injuries
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
ATE443699T1 (de) * 2002-12-06 2009-10-15 Purdue Research Foundation Pyridine zur behandlung von verletztemsäugetiernervengewebe
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
JP4533590B2 (ja) * 2003-02-28 2010-09-01 ファイザー株式会社 脊髄損傷患者における疼痛又は痙性軽減用医薬組成物
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
EP2995305B1 (de) * 2011-01-28 2020-03-04 Acorda Therapeutics, Inc. Verwendung von kaliumkanalblockern zur behandlung von zerebralparese
US8924325B1 (en) * 2011-02-08 2014-12-30 Lockheed Martin Corporation Computerized target hostility determination and countermeasure
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508715A (en) * 1981-07-01 1985-04-02 University Of Georgia Research Foundation, Inc. Antagonism of central nervous system drugs by the administration of 4-aminopyridine alone or in combination with other drugs
EP0408650A1 (de) * 1988-04-08 1991-01-23 Massachusetts Institute Of Technology Verfahren und zusammensetzung für die behandlung neurologischer störungen
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases

Also Published As

Publication number Publication date
CZ225494A3 (en) 1995-03-15
FI943765A (fi) 1994-10-14
BR9305909A (pt) 1997-10-21
FI943765A0 (fi) 1994-08-16
HU9402647D0 (en) 1994-11-28
ATE241981T1 (de) 2003-06-15
CA2085785C (en) 2005-03-15
BG99047A (bg) 1995-06-30
AU5691194A (en) 1994-07-19
NO308644B1 (no) 2000-10-09
EP0626848B1 (de) 2003-06-04
SK96994A3 (en) 1995-04-12
DE69333014D1 (de) 2003-07-10
KR100301415B1 (ko) 2001-11-22
BG62272B1 (bg) 1999-07-30
ES2199957T3 (es) 2004-03-01
JPH08504772A (ja) 1996-05-21
NO943049D0 (no) 1994-08-17
EP0626848A1 (de) 1994-12-07
CA2085785A1 (en) 1994-06-19
HU219583B (hu) 2001-05-28
NO2012003I1 (no) 2012-02-13
HUT68171A (en) 1995-05-29
NO943049L (no) 1994-10-17
AU676251B2 (en) 1997-03-06
JP3474569B2 (ja) 2003-12-08
RU94041207A (ru) 1996-06-20
NZ258844A (en) 1997-04-24
WO1994014439A1 (en) 1994-07-07
NO2012003I2 (no) 2013-02-18
US5545648A (en) 1996-08-13
KR950700062A (ko) 1995-01-16
RU2160590C2 (ru) 2000-12-20
DE69333014T2 (de) 2004-05-06
CZ284441B6 (cs) 1998-11-11

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MK4A Expiry of patent

Expiry date: 20131220