ATE191342T1 - Verwendung von riluzol zur behandlung mitochondrialer erkrankungen - Google Patents
Verwendung von riluzol zur behandlung mitochondrialer erkrankungenInfo
- Publication number
- ATE191342T1 ATE191342T1 AT95906378T AT95906378T ATE191342T1 AT E191342 T1 ATE191342 T1 AT E191342T1 AT 95906378 T AT95906378 T AT 95906378T AT 95906378 T AT95906378 T AT 95906378T AT E191342 T1 ATE191342 T1 AT E191342T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- riluzole
- mitochondrial diseases
- date jul
- syndrome
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9400249A FR2714828B1 (fr) | 1994-01-12 | 1994-01-12 | Application du riluzole dans le traitement des maladies mitochondriales. |
PCT/FR1995/000023 WO1995019170A1 (fr) | 1994-01-12 | 1995-01-09 | Application du riluzole dans le traitement des maladies mitochondriales |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE191342T1 true ATE191342T1 (de) | 2000-04-15 |
Family
ID=9458947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95906378T ATE191342T1 (de) | 1994-01-12 | 1995-01-09 | Verwendung von riluzol zur behandlung mitochondrialer erkrankungen |
Country Status (14)
Country | Link |
---|---|
US (1) | US5686475A (de) |
EP (1) | EP0738147B1 (de) |
JP (1) | JP3585045B2 (de) |
AT (1) | ATE191342T1 (de) |
AU (1) | AU1458495A (de) |
DE (1) | DE69516110T2 (de) |
DK (1) | DK0738147T3 (de) |
ES (1) | ES2145902T3 (de) |
FR (1) | FR2714828B1 (de) |
GR (1) | GR3033005T3 (de) |
IL (1) | IL112288A (de) |
PT (1) | PT738147E (de) |
WO (1) | WO1995019170A1 (de) |
ZA (1) | ZA95150B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20000048847A (ko) * | 1996-10-01 | 2000-07-25 | 스즈키 다다시 | 미토콘드리아 막 안정화제 |
US5922746A (en) * | 1997-03-27 | 1999-07-13 | Allergan | Inhibition of noninactivating Na channels of mammalian optic nerve as a means of preventing optic nerve degeneration associated with glaucoma |
FR2774592B1 (fr) * | 1998-02-06 | 2000-03-17 | Rhone Poulenc Rorer Sa | Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet |
FR2774908B1 (fr) * | 1998-02-17 | 2000-06-23 | Centre Nat Rech Scient | Utilisation d'inhibiteur de la liberation du glutamate dans le traitement de l'ischemie retinienne |
FR2787028B1 (fr) | 1998-12-15 | 2002-10-18 | Aventis Pharma Sa | Utilisation du riluzole dans le traitement des traumatismes acoustiques |
WO2000066121A1 (en) * | 1999-04-29 | 2000-11-09 | Centre National De La Recherche Scientifique (C.N.R.S.) | A method for the prevention of ischemic spinal cord injury caused by aortic crossclamping |
AU2002239329B2 (en) | 2000-11-22 | 2006-08-10 | Allergan, Inc. | A high-throughput screen for identifying channel blockers that selectively distinguish transient from persistent sodium channels |
US6479458B1 (en) | 2001-11-08 | 2002-11-12 | Allergan, Inc. | Targeting the reverse mode of the Na+/Ca2+ exchanger for the treatment of optic neuropathy associated with glaucoma and ischemic optic neuropathy |
US7361478B2 (en) | 2001-11-20 | 2008-04-22 | Allergan, Inc. | High-throughput screen for identifying selective persistent sodium channels channel blockers |
JP2004182705A (ja) * | 2002-10-11 | 2004-07-02 | Yasutoshi Koga | ミトコンドリア機能異常に起因する疾患における臨床症状発現の予防・治療用組成物 |
CA2661448A1 (en) | 2005-08-25 | 2007-03-01 | Steven Michael Weiss | Reducing myocardial damage and the incidence of arrhythmia arising from loss, reduction or interruption in coronary blood flow |
EP2243476A1 (de) * | 2009-04-17 | 2010-10-27 | Centre National de la Recherche Scientifique | Verbindungen zur Behandlung von mitochondrialen Erkrankungen |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
ES2043070T3 (es) * | 1988-12-15 | 1993-12-16 | Rhone Poulenc Sante | Procedimiento para la preparacion de derivados de la benzotiazolamina-2. |
US5236940A (en) * | 1988-12-15 | 1993-08-17 | Rhone-Poulenc Sante | Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation |
US5334618A (en) * | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
US5455279A (en) * | 1991-04-19 | 1995-10-03 | The Children's Medical Center Corporation | Regimen method of mediating neuronal damage using nitroglycerine |
FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
-
1994
- 1994-01-12 FR FR9400249A patent/FR2714828B1/fr not_active Expired - Fee Related
-
1995
- 1995-01-09 DE DE69516110T patent/DE69516110T2/de not_active Expired - Lifetime
- 1995-01-09 AT AT95906378T patent/ATE191342T1/de active
- 1995-01-09 IL IL11228895A patent/IL112288A/xx not_active IP Right Cessation
- 1995-01-09 PT PT95906378T patent/PT738147E/pt unknown
- 1995-01-09 AU AU14584/95A patent/AU1458495A/en not_active Abandoned
- 1995-01-09 EP EP95906378A patent/EP0738147B1/de not_active Expired - Lifetime
- 1995-01-09 US US08/669,530 patent/US5686475A/en not_active Expired - Lifetime
- 1995-01-09 JP JP51887095A patent/JP3585045B2/ja not_active Expired - Fee Related
- 1995-01-09 ES ES95906378T patent/ES2145902T3/es not_active Expired - Lifetime
- 1995-01-09 DK DK95906378T patent/DK0738147T3/da active
- 1995-01-09 WO PCT/FR1995/000023 patent/WO1995019170A1/fr active IP Right Grant
- 1995-01-10 ZA ZA95150A patent/ZA95150B/xx unknown
-
2000
- 2000-04-06 GR GR990403136T patent/GR3033005T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69516110D1 (de) | 2000-05-11 |
IL112288A0 (en) | 1995-03-30 |
EP0738147A1 (de) | 1996-10-23 |
ES2145902T3 (es) | 2000-07-16 |
WO1995019170A1 (fr) | 1995-07-20 |
US5686475A (en) | 1997-11-11 |
DE69516110T2 (de) | 2000-09-28 |
FR2714828B1 (fr) | 1996-02-02 |
PT738147E (pt) | 2000-08-31 |
FR2714828A1 (fr) | 1995-07-13 |
DK0738147T3 (da) | 2000-07-10 |
AU1458495A (en) | 1995-08-01 |
JPH09507498A (ja) | 1997-07-29 |
ZA95150B (en) | 1995-09-07 |
GR3033005T3 (en) | 2000-07-31 |
EP0738147B1 (de) | 2000-04-05 |
JP3585045B2 (ja) | 2004-11-04 |
IL112288A (en) | 1999-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEFA | Change of the company name |