ATE196847T1 - Verwendung von mannosephosphaten zur behandlung von fibrotischen störungen - Google Patents

Verwendung von mannosephosphaten zur behandlung von fibrotischen störungen

Info

Publication number
ATE196847T1
ATE196847T1 AT93906680T AT93906680T ATE196847T1 AT E196847 T1 ATE196847 T1 AT E196847T1 AT 93906680 T AT93906680 T AT 93906680T AT 93906680 T AT93906680 T AT 93906680T AT E196847 T1 ATE196847 T1 AT E196847T1
Authority
AT
Austria
Prior art keywords
pct
mannose
fibrotic disorders
phosphates
sec
Prior art date
Application number
AT93906680T
Other languages
English (en)
Inventor
Mark William James Ferguson
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Application granted granted Critical
Publication of ATE196847T1 publication Critical patent/ATE196847T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT93906680T 1992-03-17 1993-03-16 Verwendung von mannosephosphaten zur behandlung von fibrotischen störungen ATE196847T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929205800A GB9205800D0 (en) 1992-03-17 1992-03-17 Treatment of fibrotic disorders
PCT/GB1993/000541 WO1993018777A1 (en) 1992-03-17 1993-03-16 Use of mannose phosphates for the treatment of fibrotic disorders

Publications (1)

Publication Number Publication Date
ATE196847T1 true ATE196847T1 (de) 2000-10-15

Family

ID=10712310

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93906680T ATE196847T1 (de) 1992-03-17 1993-03-16 Verwendung von mannosephosphaten zur behandlung von fibrotischen störungen

Country Status (18)

Country Link
US (1) US5520926A (de)
EP (1) EP0728006B1 (de)
JP (1) JP3930556B2 (de)
AT (1) ATE196847T1 (de)
AU (1) AU667887B2 (de)
CA (1) CA2130805C (de)
DE (1) DE69329559T2 (de)
DK (1) DK0728006T3 (de)
ES (1) ES2151903T3 (de)
GB (2) GB9205800D0 (de)
GR (1) GR3035117T3 (de)
IL (1) IL105079A (de)
NO (1) NO306808B1 (de)
NZ (1) NZ249915A (de)
PT (1) PT728006E (de)
SG (1) SG49899A1 (de)
WO (1) WO1993018777A1 (de)
ZA (1) ZA931869B (de)

Families Citing this family (41)

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GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
SE9403137D0 (sv) * 1994-09-20 1994-09-20 Perstorp Ab Derivatives of carbohydrates and compositions containing them
GB9516012D0 (en) * 1995-08-04 1995-10-04 Univ Manchester Pharmaceutical composition
US6566339B1 (en) 1995-08-04 2003-05-20 Renovo Limited Pharmaceutical composition
GB2306481A (en) * 1995-10-21 1997-05-07 Univ Manchester Pharmaceutical comprising a stimulator of activin and/or inhibin
US6093388A (en) * 1996-08-12 2000-07-25 Btg International Limited Mannose-6-phosphate composition and its use in treating fibrotic disorders
GB9616896D0 (en) * 1996-08-12 1996-09-25 British Tech Group Pharmaceutical compositions
DE19758059C2 (de) * 1997-12-29 2001-10-04 Thorsten Marquardt Verwendung von Mannose zur Bekämpfung der Proteinverlust-Enteropathie
US7255883B2 (en) * 2000-06-23 2007-08-14 Healagenics, Inc. Agent for reduction of scar formation by using wound alkalinization
EP1345602B1 (de) * 2000-11-30 2010-07-21 Novodermix International Limited Heilung von wunden
US20030031689A1 (en) * 2001-08-09 2003-02-13 Thomas Mammone Method of skin exfoliation
US6822033B2 (en) 2001-11-19 2004-11-23 United States Gypsum Company Compositions and methods for treating set gypsum
JP4564261B2 (ja) * 2002-01-22 2010-10-20 ジェンザイム、コーポレーション 慢性的移植片拒絶反応の治療と予防のためのＴＧＦ−β拮抗薬の使用
RU2308954C2 (ru) * 2002-05-09 2007-10-27 Медиджинез Фармацевтическая композиция для лечения ран, содержащая плазму или сыворотку крови
GB0217136D0 (en) 2002-07-24 2002-09-04 Renovo Ltd Wound healing & treatment of fibrosis
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
US20050136126A1 (en) * 2003-03-17 2005-06-23 Cambridgemed, Inc. Agent for reduction of scar formation by using wound alkalinization
JP4634027B2 (ja) * 2003-05-16 2011-02-16 花王株式会社 ビタミンｄ様活性代替用剤
US7276486B2 (en) * 2004-03-15 2007-10-02 Kimberly-Clark Worldwide, Inc. Compositions for vaginal treatment
AU2005230848B9 (en) * 2004-03-31 2011-06-02 Genentech, Inc. Humanized anti-TGF-beta antibodies
EP1809324A4 (de) * 2004-10-13 2009-02-25 Univ Ohio State Res Found Verfahren zur behandlung oder prävention von viralen lymphoproliferativen erkrankungen
US7323184B2 (en) * 2005-08-22 2008-01-29 Healagenics, Inc. Compositions and methods for the treatment of wounds and the reduction of scar formation
US20070048391A1 (en) * 2005-08-23 2007-03-01 Cambridgemed, Inc. Composition for reduction of scar formation on wound scar
JP5602365B2 (ja) 2005-10-25 2014-10-08 ザ・ジョンズ・ホプキンス・ユニバーシティ マルファン症候群及び関連疾患を治療するための方法及び組成物。
EP1998810A4 (de) 2006-03-13 2009-09-02 Univ Johns Hopkins Erhöhung der endothelialen thromboresistenz
PL2083863T3 (pl) 2006-10-03 2015-08-31 Genzyme Corp Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej
US8070895B2 (en) 2007-02-12 2011-12-06 United States Gypsum Company Water resistant cementitious article and method for preparing same
US8329308B2 (en) 2009-03-31 2012-12-11 United States Gypsum Company Cementitious article and method for preparing the same
GB0910078D0 (en) * 2009-06-11 2009-07-22 Renovo Ltd Uses of mannose-6-phosphate
GB0916333D0 (en) 2009-09-17 2009-10-28 Renovo Ltd Improvement of tendon repair
GB0916334D0 (en) * 2009-09-17 2009-10-28 Renovo Ltd Inhibition of tendon adhesions
EP3117709B1 (de) 2010-03-12 2018-08-01 Genzyme Corporation Kombinationstherapie zur behandlung von brustkrebs
US20140170236A1 (en) * 2010-11-05 2014-06-19 Priscilla Hayes Petty Use of phosphoric acid
WO2012090997A1 (ja) 2010-12-27 2012-07-05 京都府公立大学法人 ｉＰＳ細胞とその製造法
EP2737083A1 (de) 2011-07-27 2014-06-04 INSERM (Institut National de la Santé et de la Recherche Scientifique) Verfahren zur diagnose und behandlung des myhre-syndroms
CA2853484C (en) 2011-10-26 2018-08-21 Seattle Children's Research Institute Cysteamine in the treatment of fibrotic disease
EP2799537B1 (de) 2011-12-28 2021-09-22 Kyoto Prefectural Public University Corporation Normalisierung der züchtung von hornhautendothelzellen
EP3804760A1 (de) 2013-10-31 2021-04-14 Kyoto Prefectural Public University Corporation Therapeutikum für erkrankungen im zusammenhang mit endoplasmatischem retikulumszelltod im hornhautendothel
US10882903B2 (en) 2015-05-18 2021-01-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and compositions for treating an alphavirus infection
WO2023172636A1 (en) * 2022-03-08 2023-09-14 University Of Mississippi Medical Center Articles and methods for improved tissue healing
CN115260256A (zh) * 2022-07-22 2022-11-01 河南中医药大学 一种甘露糖磷酸化衍生物及其制备方法和应用

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BE756953A (fr) * 1969-10-02 1971-04-01 Merck & Co Inc Potentialisation d'antibiotiques
JPS5631156B2 (de) * 1973-09-25 1981-07-20
IT1170618B (it) * 1981-01-13 1987-06-03 Foscama Biomed Chim Farma Preparato farmacologico di frutto sio-1,6-difosfato ad azione terapeutica nei pazienti ustionati
US4703040A (en) * 1985-04-03 1987-10-27 Markov Angel K Treatment of adult respiratory distress syndrome (ARDS) using fructose diphosphate (FDP)
US4889844A (en) * 1985-10-22 1989-12-26 Silvetti Sr Anthony N Fructose containing wound healing preparation
EP0221728B1 (de) * 1985-10-22 1992-07-15 Anthony N. Silvetti, Sr. Monosaccharide enthaltende Zusammensetzung zum Heilen von Wunden
AU607690B2 (en) * 1985-12-24 1991-03-14 Marion Laboratories, Inc. Use of synthetic sulfated saccharides to enhance wound healing
JPS62243675A (ja) * 1986-04-15 1987-10-24 Kao Corp ｐＨ緩衝法
WO1990001938A1 (en) * 1988-08-19 1990-03-08 The Australian National University Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
GB8917414D0 (en) * 1989-07-29 1989-09-13 Translift Material Handling Narrow aisle lift truck
CA2065860C (en) * 1989-09-29 2001-03-27 Wayne A. Border Inhibiting transforming growth factor .beta. to prevent accumulation of extracellular matrix
SE8904354D0 (sv) * 1989-12-21 1989-12-21 Matti Siren A pharmaceutical composition
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
JPH0558868A (ja) * 1991-08-27 1993-03-09 Kao Corp 親水性紫外線吸収剤及びこれを含有する化粧料
AU3943793A (en) * 1992-04-01 1993-11-08 Whittier Institute For Diabetes And Endocrinology, The Methods of inhibiting or enhancing scar formation in the CNS
JPH09155319A (ja) * 1995-12-13 1997-06-17 Takeo Tsutsui 重金属含有焼却灰等、シュレッダーダストの無公害化処理方法および再利用材の製造方法

Also Published As

Publication number Publication date
NO943451D0 (no) 1994-09-16
GB2265310B (en) 1996-09-25
GB2265310A (en) 1993-09-29
WO1993018777A1 (en) 1993-09-30
NO943451L (no) 1994-09-16
GB9205800D0 (en) 1992-04-29
GR3035117T3 (en) 2001-03-30
JP3930556B2 (ja) 2007-06-13
CA2130805C (en) 2003-06-24
IL105079A (en) 1998-06-15
ZA931869B (en) 1994-09-16
DE69329559T2 (de) 2001-05-31
AU667887B2 (en) 1996-04-18
ES2151903T3 (es) 2001-01-16
DE69329559D1 (de) 2000-11-16
GB9305344D0 (en) 1993-05-05
EP0728006A1 (de) 1996-08-28
IL105079A0 (en) 1993-07-08
US5520926A (en) 1996-05-28
SG49899A1 (en) 1998-06-15
CA2130805A1 (en) 1993-09-30
NZ249915A (en) 1996-08-27
JPH07504909A (ja) 1995-06-01
DK0728006T3 (da) 2000-10-30
PT728006E (pt) 2001-04-30
NO306808B1 (no) 1999-12-27
EP0728006B1 (de) 2000-10-11
AU3759093A (en) 1993-10-21

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Legal Events

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UEP Publication of translation of european patent specification