ATE234614T1 - Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren - Google Patents
Verwendung von selegilin zur behandlung von gehörverlust bei säugetierenInfo
- Publication number
- ATE234614T1 ATE234614T1 AT96917093T AT96917093T ATE234614T1 AT E234614 T1 ATE234614 T1 AT E234614T1 AT 96917093 T AT96917093 T AT 96917093T AT 96917093 T AT96917093 T AT 96917093T AT E234614 T1 ATE234614 T1 AT E234614T1
- Authority
- AT
- Austria
- Prior art keywords
- selegiline
- mammals
- hearing loss
- treat hearing
- treat
- Prior art date
Links
- 206010011878 Deafness Diseases 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title abstract 2
- 230000010370 hearing loss Effects 0.000 title abstract 2
- 231100000888 hearing loss Toxicity 0.000 title abstract 2
- 208000016354 hearing loss disease Diseases 0.000 title abstract 2
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 title abstract 2
- 229960003946 selegiline Drugs 0.000 title abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/475,186 US5561163A (en) | 1990-08-31 | 1995-06-07 | Treating hearing loss with deprenyl |
| PCT/US1996/008642 WO1996040094A1 (en) | 1995-06-07 | 1996-06-03 | Use of selegiline to treat hearing loss in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234614T1 true ATE234614T1 (de) | 2003-04-15 |
Family
ID=23886552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96917093T ATE234614T1 (de) | 1995-06-07 | 1996-06-03 | Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5561163A (de) |
| EP (1) | EP0831798B1 (de) |
| JP (1) | JP3094305B2 (de) |
| AT (1) | ATE234614T1 (de) |
| AU (1) | AU693704B2 (de) |
| CA (1) | CA2221255C (de) |
| DE (1) | DE69626816T2 (de) |
| ES (1) | ES2194104T3 (de) |
| WO (1) | WO1996040094A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005102345A1 (en) * | 2004-03-30 | 2005-11-03 | Alcon, Inc. | Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
| WO2005118539A1 (en) | 2004-06-01 | 2005-12-15 | F.Hoffmann-La Roche Ag | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor |
| WO2014159356A1 (en) | 2013-03-14 | 2014-10-02 | The Brigham And Women's Hospital, Inc. | Compositions and methods for epithelial stem cell expansion and culture |
| IL299964A (en) | 2014-09-03 | 2023-03-01 | Massachusetts Inst Technology | Preparations, systems and methods for producing hair cells in the inner ear to treat hearing loss |
| JP2019506153A (ja) | 2016-01-08 | 2019-03-07 | マサチューセッツ インスティテュート オブ テクノロジー | 分化した腸内分泌細胞およびインスリン産生細胞の作製 |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US11260130B2 (en) | 2016-03-02 | 2022-03-01 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| CN110392686A (zh) | 2016-12-30 | 2019-10-29 | 频率治疗公司 | 1h-吡咯-2,5-二酮化合物以及使用它们来诱导干/祖支持细胞自我更新的方法 |
| WO2020037326A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating foxo |
| CA3109647A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating jag-1 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA871155A (en) * | 1971-05-18 | Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt | Optically active phenyl isopropylamine derivatives having pharmaceutical properties and their preparation | |
| HU187775B (en) * | 1982-07-14 | 1986-02-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | New process for producing propargile-amines of pharmaceutical activity |
| HU193662B (en) * | 1983-12-20 | 1987-11-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing synergetic pharmaceutical composition of antidepressive aktivity |
| US4916151A (en) * | 1985-12-05 | 1990-04-10 | Merrell Dow Pharmaceuticals Inc. | Method of treating parkinson's syndrome |
| US4871550A (en) * | 1986-09-05 | 1989-10-03 | Millman Phillip L | Nutrient composition for athletes and method of making and using the same |
| US4861800A (en) * | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| US5192808A (en) * | 1990-08-31 | 1993-03-09 | Deprenyl Animal Health, Inc. | Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease) |
| CA2039194C (en) * | 1990-08-31 | 1997-01-28 | Norton W. Milgram | Uses of l-deprenyl and compositions for same |
| SE9301112D0 (sv) * | 1993-04-02 | 1993-04-02 | Orion-Yhtymae Oy | A new composition |
-
1995
- 1995-06-07 US US08/475,186 patent/US5561163A/en not_active Expired - Lifetime
-
1996
- 1996-06-03 DE DE69626816T patent/DE69626816T2/de not_active Expired - Fee Related
- 1996-06-03 EP EP96917093A patent/EP0831798B1/de not_active Expired - Lifetime
- 1996-06-03 AU AU59772/96A patent/AU693704B2/en not_active Ceased
- 1996-06-03 JP JP09501174A patent/JP3094305B2/ja not_active Expired - Fee Related
- 1996-06-03 AT AT96917093T patent/ATE234614T1/de not_active IP Right Cessation
- 1996-06-03 ES ES96917093T patent/ES2194104T3/es not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/008642 patent/WO1996040094A1/en not_active Ceased
- 1996-06-03 CA CA002221255A patent/CA2221255C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3094305B2 (ja) | 2000-10-03 |
| US5561163A (en) | 1996-10-01 |
| ES2194104T3 (es) | 2003-11-16 |
| WO1996040094A1 (en) | 1996-12-19 |
| CA2221255A1 (en) | 1996-12-19 |
| EP0831798B1 (de) | 2003-03-19 |
| AU5977296A (en) | 1996-12-30 |
| JPH10510843A (ja) | 1998-10-20 |
| EP0831798A1 (de) | 1998-04-01 |
| DE69626816D1 (de) | 2003-04-24 |
| AU693704B2 (en) | 1998-07-02 |
| CA2221255C (en) | 2005-11-08 |
| DE69626816T2 (de) | 2004-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |