ATE228514T1 - Indolin-derivate verwendbar als 5-ht-2c rezeptor- antagonisten - Google Patents
Indolin-derivate verwendbar als 5-ht-2c rezeptor- antagonistenInfo
- Publication number
- ATE228514T1 ATE228514T1 AT97928224T AT97928224T ATE228514T1 AT E228514 T1 ATE228514 T1 AT E228514T1 AT 97928224 T AT97928224 T AT 97928224T AT 97928224 T AT97928224 T AT 97928224T AT E228514 T1 ATE228514 T1 AT E228514T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor antagonists
- indoline derivatives
- derivatives usable
- usable
- indoline
- Prior art date
Links
- 102000006902 5-HT2C Serotonin Receptor Human genes 0.000 title 1
- 108010072553 5-HT2C Serotonin Receptor Proteins 0.000 title 1
- 150000002476 indolines Chemical class 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
| PCT/EP1997/003156 WO1997048699A1 (en) | 1996-06-20 | 1997-06-16 | Indoline derivatives useful as 5-ht-2c receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228514T1 true ATE228514T1 (de) | 2002-12-15 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97928224T ATE228514T1 (de) | 1996-06-20 | 1997-06-16 | Indolin-derivate verwendbar als 5-ht-2c rezeptor- antagonisten |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (OSRAM) |
| EP (1) | EP0912554B1 (OSRAM) |
| JP (1) | JP2000512306A (OSRAM) |
| KR (1) | KR20000022045A (OSRAM) |
| CN (1) | CN1229408A (OSRAM) |
| AP (2) | AP9801410A0 (OSRAM) |
| AR (1) | AR008243A1 (OSRAM) |
| AT (1) | ATE228514T1 (OSRAM) |
| AU (1) | AU718597B2 (OSRAM) |
| BG (1) | BG103089A (OSRAM) |
| BR (1) | BR9709911A (OSRAM) |
| CA (1) | CA2258240A1 (OSRAM) |
| CO (1) | CO4890847A1 (OSRAM) |
| CZ (1) | CZ420598A3 (OSRAM) |
| DE (1) | DE69717449T2 (OSRAM) |
| DZ (1) | DZ2250A1 (OSRAM) |
| EA (1) | EA001780B1 (OSRAM) |
| ES (1) | ES2187783T3 (OSRAM) |
| GB (1) | GB9612883D0 (OSRAM) |
| HU (1) | HUP9903439A3 (OSRAM) |
| ID (1) | ID19433A (OSRAM) |
| IL (1) | IL127417A0 (OSRAM) |
| MA (1) | MA24214A1 (OSRAM) |
| NO (1) | NO985972L (OSRAM) |
| NZ (1) | NZ333229A (OSRAM) |
| OA (1) | OA10944A (OSRAM) |
| PE (1) | PE86698A1 (OSRAM) |
| PL (1) | PL330796A1 (OSRAM) |
| SK (1) | SK282706B6 (OSRAM) |
| TR (1) | TR199802661T2 (OSRAM) |
| TW (1) | TW382015B (OSRAM) |
| WO (1) | WO1997048699A1 (OSRAM) |
| ZA (1) | ZA975415B (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3030899A (en) * | 1998-02-25 | 1999-09-15 | Smithkline Beecham Plc | Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| MXPA04005151A (es) | 2001-11-28 | 2004-08-11 | Upjohn Co | Compuestos terapeuticos. |
| WO2003076426A2 (en) * | 2002-03-04 | 2003-09-18 | Pharmacia & Upjohn Company | Pyridinyloxy derivatives as 5-ht receptor ligands |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| AU2010204995A1 (en) | 2009-01-16 | 2011-08-18 | Massachusetts Institute Of Technology | Diagnosis and treatment of autism spectrum disorders |
| EP2651403B1 (en) | 2010-12-17 | 2020-12-02 | Glaxo Group Limited | Use of lp-pla2 inhibitors in the treatment and prevention of eye diseases |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| AU4704693A (en) * | 1992-08-20 | 1994-03-15 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT-2C and 5HT-2B antagonists |
| GB9313913D0 (en) * | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| FI973205L (fi) * | 1995-02-02 | 1997-10-01 | Smithkline Beecham Plc | Indolijohdannaisia 5-HT-reseptoriantagonisteina |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/en not_active Ceased
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-16 EP EP97928224A patent/EP0912554B1/en not_active Expired - Lifetime
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 CA CA002258240A patent/CA2258240A1/en not_active Abandoned
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Ceased
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
-
1998
- 1998-12-18 NO NO985972A patent/NO985972L/no unknown
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |