DE69617010D1 - Isazole derivate als fibrinogen-rezeptor-antagonisten - Google Patents
Isazole derivate als fibrinogen-rezeptor-antagonistenInfo
- Publication number
- DE69617010D1 DE69617010D1 DE69617010T DE69617010T DE69617010D1 DE 69617010 D1 DE69617010 D1 DE 69617010D1 DE 69617010 T DE69617010 T DE 69617010T DE 69617010 T DE69617010 T DE 69617010T DE 69617010 D1 DE69617010 D1 DE 69617010D1
- Authority
- DE
- Germany
- Prior art keywords
- isazole
- derivatives
- receptor antagonists
- fibrinogen receptor
- fibrinogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44959795A | 1995-05-24 | 1995-05-24 | |
US58694096A | 1996-01-11 | 1996-01-11 | |
PCT/US1996/007645 WO1996037482A1 (en) | 1995-05-24 | 1996-05-24 | Improved isoxazoline fibrinogen receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69617010D1 true DE69617010D1 (de) | 2001-12-20 |
DE69617010T2 DE69617010T2 (de) | 2002-06-27 |
Family
ID=27035737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69617010T Expired - Fee Related DE69617010T2 (de) | 1995-05-24 | 1996-05-24 | Isazole derivate als fibrinogen-rezeptor-antagonisten |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0832077B1 (de) |
JP (1) | JPH11511745A (de) |
AR (1) | AR002996A1 (de) |
AT (1) | ATE208764T1 (de) |
AU (1) | AU5876196A (de) |
CA (1) | CA2222050A1 (de) |
DE (1) | DE69617010T2 (de) |
IL (1) | IL118007A0 (de) |
WO (1) | WO1996037482A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9602646D0 (sv) | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically-useful compounds |
WO1998006707A1 (en) * | 1996-08-15 | 1998-02-19 | Dupont Pharmaceuticals Company | Cyclic carbamates and isoxazolidines as iib/iiia antagonists |
US5998424A (en) | 1997-06-19 | 1999-12-07 | Dupont Pharmaceuticals Company | Inhibitors of factor Xa with a neutral P1 specificity group |
KR20010013977A (ko) | 1997-06-19 | 2001-02-26 | 블레어 큐. 퍼거슨 | 중성 p1 특이성 기를 갖는 인자 xa의 억제제 |
US6319937B1 (en) * | 1998-11-18 | 2001-11-20 | Dupont Pharmaceuticals Company | Isoxazoline fibrinogen receptor antagonists |
TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
US5239113A (en) * | 1991-10-15 | 1993-08-24 | Monsanto Company | Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof |
EP0730589B1 (de) * | 1993-11-24 | 1998-07-08 | The Du Pont Merck Pharmaceutical Company | Isoxazoline derivate anwendbar als fibrinogen rezeptor antagonisten |
-
1996
- 1996-04-23 IL IL11800796A patent/IL118007A0/xx unknown
- 1996-05-16 AR AR10259696A patent/AR002996A1/es unknown
- 1996-05-24 AT AT96920475T patent/ATE208764T1/de not_active IP Right Cessation
- 1996-05-24 JP JP8535898A patent/JPH11511745A/ja active Pending
- 1996-05-24 DE DE69617010T patent/DE69617010T2/de not_active Expired - Fee Related
- 1996-05-24 EP EP96920475A patent/EP0832077B1/de not_active Expired - Lifetime
- 1996-05-24 CA CA002222050A patent/CA2222050A1/en not_active Abandoned
- 1996-05-24 WO PCT/US1996/007645 patent/WO1996037482A1/en active IP Right Grant
- 1996-05-24 AU AU58761/96A patent/AU5876196A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1996037482A1 (en) | 1996-11-28 |
AU5876196A (en) | 1996-12-11 |
DE69617010T2 (de) | 2002-06-27 |
EP0832077A1 (de) | 1998-04-01 |
EP0832077B1 (de) | 2001-11-14 |
IL118007A0 (en) | 1996-08-04 |
ATE208764T1 (de) | 2001-11-15 |
JPH11511745A (ja) | 1999-10-12 |
AR002996A1 (es) | 1998-05-27 |
CA2222050A1 (en) | 1996-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |