AR002996A1 - Isoxazolinas mejoradas antagonistas del receptore de fibrinogeno. - Google Patents

Isoxazolinas mejoradas antagonistas del receptore de fibrinogeno.

Info

Publication number
AR002996A1
AR002996A1 AR10259696A AR10259696A AR002996A1 AR 002996 A1 AR002996 A1 AR 002996A1 AR 10259696 A AR10259696 A AR 10259696A AR 10259696 A AR10259696 A AR 10259696A AR 002996 A1 AR002996 A1 AR 002996A1
Authority
AR
Argentina
Prior art keywords
isoxazolines
receptor antagonists
fibrinogen receptor
enhanced
enhanced fibrinogen
Prior art date
Application number
AR10259696A
Other languages
English (en)
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of AR002996A1 publication Critical patent/AR002996A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AR10259696A 1995-05-24 1996-05-16 Isoxazolinas mejoradas antagonistas del receptore de fibrinogeno. AR002996A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44959795A 1995-05-24 1995-05-24
US58694096A 1996-01-11 1996-01-11

Publications (1)

Publication Number Publication Date
AR002996A1 true AR002996A1 (es) 1998-05-27

Family

ID=27035737

Family Applications (1)

Application Number Title Priority Date Filing Date
AR10259696A AR002996A1 (es) 1995-05-24 1996-05-16 Isoxazolinas mejoradas antagonistas del receptore de fibrinogeno.

Country Status (9)

Country Link
EP (1) EP0832077B1 (es)
JP (1) JPH11511745A (es)
AR (1) AR002996A1 (es)
AT (1) ATE208764T1 (es)
AU (1) AU5876196A (es)
CA (1) CA2222050A1 (es)
DE (1) DE69617010T2 (es)
IL (1) IL118007A0 (es)
WO (1) WO1996037482A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602646D0 (sv) * 1996-07-04 1996-07-04 Astra Ab Pharmaceutically-useful compounds
JP2000516230A (ja) * 1996-08-15 2000-12-05 デュポン ファーマシューティカルズ カンパニー Ｉｉｂ／ｉｉｉａ拮抗薬としての環状カルバメート類およびイソオキサゾリジン類
EA200000048A1 (ru) 1997-06-19 2000-08-28 Дюпон Фармасьютикалз Компани ИНГИБИТОРЫ ФАКТОРА Ха, СОДЕРЖАЩИЕ ГРУППУ С НЕЙТРАЛЬНОЙ P1-СПЕЦИФИЧНОСТЬЮ
US5998424A (en) 1997-06-19 1999-12-07 Dupont Pharmaceuticals Company Inhibitors of factor Xa with a neutral P1 specificity group
US6319937B1 (en) * 1998-11-18 2001-11-20 Dupont Pharmaceuticals Company Isoxazoline fibrinogen receptor antagonists
TWI288745B (en) 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
US5239113A (en) * 1991-10-15 1993-08-24 Monsanto Company Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof
DK0730589T3 (da) * 1993-11-24 1999-02-01 Du Pont Pharm Co Isoxazolinforbindelser, der er nyttige som fibrinogenreceptorantagonister

Also Published As

Publication number Publication date
CA2222050A1 (en) 1996-11-28
ATE208764T1 (de) 2001-11-15
EP0832077B1 (en) 2001-11-14
DE69617010T2 (de) 2002-06-27
DE69617010D1 (de) 2001-12-20
IL118007A0 (en) 1996-08-04
AU5876196A (en) 1996-12-11
EP0832077A1 (en) 1998-04-01
WO1996037482A1 (en) 1996-11-28
JPH11511745A (ja) 1999-10-12

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