ATE221206T1 - Verfahren zur verifikation des aufgesaugten volumens in einem automatischen diagnostischen system - Google Patents

Verfahren zur verifikation des aufgesaugten volumens in einem automatischen diagnostischen system

Info

Publication number
ATE221206T1
ATE221206T1 AT98954685T AT98954685T ATE221206T1 AT E221206 T1 ATE221206 T1 AT E221206T1 AT 98954685 T AT98954685 T AT 98954685T AT 98954685 T AT98954685 T AT 98954685T AT E221206 T1 ATE221206 T1 AT E221206T1
Authority
AT
Austria
Prior art keywords
sample
volume
fluid
aspiration
foam
Prior art date
Application number
AT98954685T
Other languages
English (en)
Inventor
Jeffrey S Dorenkott
Carl F Panek
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE221206T1 publication Critical patent/ATE221206T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1032—Dilution or aliquotting
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/115831—Condition or time responsive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Testing Of Engines (AREA)
  • Control Of Positive-Displacement Air Blowers (AREA)
  • Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)
AT98954685T 1997-12-05 1998-12-02 Verfahren zur verifikation des aufgesaugten volumens in einem automatischen diagnostischen system ATE221206T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/985,878 US6060320A (en) 1997-12-05 1997-12-05 Method of verifying aspirated volume in automatic diagnostic system
PCT/IB1998/001914 WO1999030170A1 (en) 1997-12-05 1998-12-02 Method of verifying aspirated volume in automatic diagnostic system

Publications (1)

Publication Number Publication Date
ATE221206T1 true ATE221206T1 (de) 2002-08-15

Family

ID=25531879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98954685T ATE221206T1 (de) 1997-12-05 1998-12-02 Verfahren zur verifikation des aufgesaugten volumens in einem automatischen diagnostischen system

Country Status (8)

Country Link
US (1) US6060320A (de)
EP (1) EP1036335B1 (de)
JP (2) JP4514174B2 (de)
AT (1) ATE221206T1 (de)
AU (1) AU1170699A (de)
DE (1) DE69806806T2 (de)
ES (1) ES2181297T3 (de)
WO (1) WO1999030170A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121049A (en) * 1997-12-05 2000-09-19 Bayer Corporation Method of verifying aspirated volume in automatic diagnostic system
US6324924B1 (en) * 1999-04-06 2001-12-04 Roger Peterson Sampling system including a sample additive mixing feature
US6270726B1 (en) * 1999-09-30 2001-08-07 Dpc Cirrus, Inc. Tube bottom sensing for small fluid samples
AU777102B2 (en) 2000-01-13 2004-09-30 Ortho-Clinical Diagnostics, Inc. Failure detection in automated clinical analyzers
WO2001065214A2 (en) 2000-02-29 2001-09-07 Gen-Probe Incorporated Fluid dispense and liquid surface verification system and method
US6370942B1 (en) * 2000-05-15 2002-04-16 Dade Behring Inc. Method for verifying the integrity of a fluid transfer
JP4076048B2 (ja) * 2000-09-22 2008-04-16 富士フイルム株式会社 定量吸引装置
US6484556B1 (en) 2000-11-13 2002-11-26 Ortho Clinical Diagnostics, Inc. Thin film detection during fluid aspiration
WO2002040160A1 (de) * 2000-11-17 2002-05-23 Tecan Trading Ag Vorrichtung und verfahren zum abtrennen von proben aus einer flüssigkeit
US6861034B1 (en) * 2000-11-22 2005-03-01 Xerox Corporation Priming mechanisms for drop ejection devices
JP3742580B2 (ja) * 2001-04-11 2006-02-08 株式会社堀場製作所 自動蓄尿検査装置
DE60221984T2 (de) * 2001-06-13 2008-05-15 Kenneth F. Los Gatos Uffenheimer Automatisches flüssigkeitsbehandlungssystem und -verfahren
JP3811652B2 (ja) * 2002-03-05 2006-08-23 株式会社日立ハイテクノロジーズ 分注装置及びそれを用いた自動分析装置
US7361509B2 (en) * 2002-04-29 2008-04-22 Ortho-Clinical Diagnostics Dynamic metered fluid volume determination method and related apparatus
CA2483694C (en) 2002-05-17 2016-04-19 Becton, Dickinson And Company Automated system for isolating, amplifying and detecting a target nucleic acid sequence
US6746966B1 (en) * 2003-01-28 2004-06-08 Taiwan Semiconductor Manufacturing Company Method to solve alignment mark blinded issues and a technology for application of semiconductor etching at a tiny area
ES2214150B1 (es) * 2003-02-27 2005-12-01 J. URIACH & CIA S.A. "nuevos derivados de pirazolopiridinas".
JP4719692B2 (ja) * 2004-02-06 2011-07-06 セヨニック エス．アー． ピペット検査装置及びそれを取り付けたピペット
US7231805B2 (en) * 2004-11-03 2007-06-19 Nordson Corporation Bubble detection with temperature compensation
US7634367B1 (en) * 2005-07-12 2009-12-15 Ortho-Clinical Diagnostics, Inc. Estimating fluidic properties and using them to improve the precision/accuracy of metered fluids and to improve the sensitivity/specificity in detecting failure modes
US8012766B2 (en) 2005-08-01 2011-09-06 Ortho-Clinical Diagnostics, Inc. Prediction of aspirated volume of a liquid
US8313711B2 (en) * 2005-11-01 2012-11-20 Freeslate, Inc. Liquid dispensing for high-throughput experimentation
US7477997B2 (en) * 2005-12-19 2009-01-13 Siemens Healthcare Diagnostics Inc. Method for ascertaining interferants in small liquid samples in an automated clinical analyzer
DE102005060862B3 (de) * 2005-12-20 2007-06-28 Stratec Biomedical Systems Ag Verfahren und Vorrichtung zur Beurteilung eines Dosiervorgangs
US7985375B2 (en) * 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
US8703492B2 (en) 2007-04-06 2014-04-22 Qiagen Gaithersburg, Inc. Open platform hybrid manual-automated sample processing system
US7867769B2 (en) 2007-09-19 2011-01-11 Siemens Healthcare Diagnostics Inc. Clog detection in a clinical sampling pipette
US7634378B2 (en) * 2007-11-30 2009-12-15 Siemens Healthcare Diagnostics Inc. Detection of insufficient sample during aspiration with a pipette
US7926325B2 (en) * 2008-04-23 2011-04-19 Siemens Healthcare Diagnostics Inc. Differentiating between abnormal sample viscosities and pipette clogging during aspiration
JP5274124B2 (ja) * 2008-07-02 2013-08-28 ベックマン コールター， インコーポレイテッド 分注装置
US7804599B2 (en) * 2008-07-24 2010-09-28 MGM Instruments, Inc. Fluid volume verification system
JP5295069B2 (ja) * 2009-10-09 2013-09-18 ベックマン コールター， インコーポレイテッド 分注装置、分析装置、および分注方法
WO2011063139A1 (en) 2009-11-18 2011-05-26 Qiagen Laboratory central control unit method and system
US8307697B2 (en) 2010-04-14 2012-11-13 Ortho-Clinical Diagnostics, Inc. Method for estimating viscosity
CA2766735C (en) 2011-02-07 2020-06-02 Ortho-Clinical Diagnostics, Inc. Determining conditions in centrifuged blood using measured pressure
DE102011081186A1 (de) * 2011-08-18 2013-02-21 Hamilton Bonaduz Ag Verfahren zum Detektieren der Oberfläche einer Flüssigkeitsprobe in einem Probenbehälter
EP2856088B1 (de) * 2012-05-31 2021-03-10 Siemens Healthcare Diagnostics Inc. Echtzeitdetektion kurzer atemzüge unter verwendung eines drucksignals
CN110243653A (zh) * 2012-11-01 2019-09-17 莱卡生物系统墨尔本私人有限公司 流体输送系统
US9522380B2 (en) * 2013-06-20 2016-12-20 Cem Corporation Control apparatus for dispensing small precise amounts of liquid reagents
EP3350573B1 (de) 2015-09-04 2021-06-16 Qualigen, Inc. Systeme und verfahren zur probenverifikation
CN110529355B (zh) * 2019-09-09 2021-05-28 英华达（上海）科技有限公司 液量控制装置及应用其的液量控制方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6264912A (ja) * 1985-09-17 1987-03-24 Minoru Atake 分注方式
CA1321940C (en) * 1987-05-02 1993-09-07 Teruaki Itoh Apparatus for distributing sample liquid
EP0341438A3 (de) * 1988-05-13 1990-11-28 Abbott Laboratories Pneumatischer Sensor
JPH0619361B2 (ja) * 1989-01-11 1994-03-16 アロカ株式会社 自動分注装置の閉塞検出方法
JPH0619362B2 (ja) * 1989-01-25 1994-03-16 アロカ株式会社 自動分注装置のショートサンプル検出方法
US5463895A (en) * 1990-11-09 1995-11-07 Abbott Laboratories Sample pipetting method
JP2725917B2 (ja) * 1991-10-04 1998-03-11 アロカ株式会社 血液試料の分注方法
JP2515938B2 (ja) * 1991-10-18 1996-07-10 アロカ株式会社 液体の吸引方法
JP2725940B2 (ja) * 1992-03-03 1998-03-11 アロカ株式会社 分注装置
JP2578296B2 (ja) * 1992-09-02 1997-02-05 アロカ株式会社 自動分注装置における漏れ検出方法
JPH06331632A (ja) * 1993-05-19 1994-12-02 Sutatsuku Syst:Kk サンプリング分注装置およびその吸入異常判定方法
JP3318629B2 (ja) * 1993-06-18 2002-08-26 ソニー株式会社 液体の吸引／排出装置及び方法
US5540081A (en) * 1993-08-31 1996-07-30 Abbott Laboratories Pipetting apparatus with clot detection
CA2148248C (en) * 1993-08-31 2000-04-04 Masaaki Takeda Pipetting apparatus with clot detection
US5537880A (en) * 1995-06-07 1996-07-23 Abbott Laboratories Automatic pipetting apparatus with leak detection and method of detecting a leak
US5750881A (en) * 1995-07-13 1998-05-12 Chiron Diagnostics Corporation Method and apparatus for aspirating and dispensing sample fluids
US5723795A (en) * 1995-12-14 1998-03-03 Abbott Laboratories Fluid handler and method of handling a fluid
ATE259068T1 (de) * 1996-05-31 2004-02-15 Packard Instrument Co Inc Vorrichtung zur handhabung von mikroflüssigkeitsmengen

Also Published As

Publication number Publication date
DE69806806D1 (de) 2002-08-29
JP2001526394A (ja) 2001-12-18
EP1036335B1 (de) 2002-07-24
ES2181297T3 (es) 2003-02-16
WO1999030170A1 (en) 1999-06-17
JP2010002423A (ja) 2010-01-07
JP4514174B2 (ja) 2010-07-28
US6060320A (en) 2000-05-09
EP1036335A1 (de) 2000-09-20
DE69806806T2 (de) 2002-11-14
AU1170699A (en) 1999-06-28

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