JP5274124B2 - 分注装置 - Google Patents
分注装置 Download PDFInfo
- Publication number
- JP5274124B2 JP5274124B2 JP2008173724A JP2008173724A JP5274124B2 JP 5274124 B2 JP5274124 B2 JP 5274124B2 JP 2008173724 A JP2008173724 A JP 2008173724A JP 2008173724 A JP2008173724 A JP 2008173724A JP 5274124 B2 JP5274124 B2 JP 5274124B2
- Authority
- JP
- Japan
- Prior art keywords
- pipe
- dispensing
- negative pressure
- bubbles
- unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/110833—Utilizing a moving indicator strip or tape
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/12—Condition responsive control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Description
図1は、本発明の実施の形態1にかかる分注装置の構成を示すブロック図である。この図1における分注装置1は、例えば、検体または試薬を含む液体試料を吸引し、吸引した液体試料を吐出して分注を行うものである。分注装置1は、図1に示すように、分注ノズル11、分注ポンプ13、圧力センサ16、給水弁17、給水ポンプ19、負圧手段24および制御機構30を備える。
つぎに、本発明の実施の形態2について説明する。上述した実施の形態1では、負圧手段24が、給水弁17を介して配管15内に接続されていたが、本発明の実施の形態2では、負圧手段53が、切替弁51を介して配管15に接続されている。
11 分注ノズル
12 ノズル駆動部
13 分注ポンプ
13a,24a,53a プランジャ
14 プランジャ駆動部
15,21,22,23,52 配管
16 圧力センサ
17,50 給水弁
19 給水ポンプ
20 タンク
24,53 負圧手段
25,54 留具
30 制御機構
31 制御部
32 入力部
33 気泡判定部
33a 処理部
33b 検出部
33c 算出部
33d 判定部
34,37 切替処理部
35 記憶部
36 出力部
40 検体容器
40a 検体
41 反応容器
42 洗浄容器
55 切替弁駆動部
Wa 脱気水
Claims (3)
- 分注ノズルと給水ポンプとの間を接続する配管に分注ポンプが接続され、該給水ポンプによって前記配管内に脱気水を供給して前記分注ノズル先端近傍まで満たし、前記分注ポンプの近傍に設けられた給水弁を閉じて分注ノズル先端側が開放された脱気水空間を形成し、この脱気水空間に対して前記分注ポンプを動作させることによって前記分注ノズルによる吸排動作を行わせる分注装置において、
切替弁を介して前記脱気水空間に接続され、負圧状態を維持した負圧手段を備え、前記脱気水空間内の気泡を除去する場合、前記切替弁を開にして前記脱気水空間を負圧状態にすることを特徴とする分注装置。 - 前記給水弁は、前記切替弁の機能を有し、前記負圧手段が接続されることを特徴とする請求項1に記載の分注装置。
- 前記負圧手段は、予め負圧状態に設定した前記脱気水を満たしておくことを特徴とする請求項1または2に記載の分注装置。
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008173724A JP5274124B2 (ja) | 2008-07-02 | 2008-07-02 | 分注装置 |
PCT/JP2009/055505 WO2010001644A1 (ja) | 2008-07-02 | 2009-03-19 | 分注装置 |
CN200980125941.5A CN102084257B (zh) | 2008-07-02 | 2009-03-19 | 分配装置 |
EP09773222.6A EP2295987B1 (en) | 2008-07-02 | 2009-03-19 | Dispensing device |
US13/001,776 US8449840B2 (en) | 2008-07-02 | 2009-03-19 | Dispensing device |
ES09773222.6T ES2608063T3 (es) | 2008-07-02 | 2009-03-19 | Dispositivo dispensador |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008173724A JP5274124B2 (ja) | 2008-07-02 | 2008-07-02 | 分注装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010014490A JP2010014490A (ja) | 2010-01-21 |
JP5274124B2 true JP5274124B2 (ja) | 2013-08-28 |
Family
ID=41465749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008173724A Expired - Fee Related JP5274124B2 (ja) | 2008-07-02 | 2008-07-02 | 分注装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US8449840B2 (ja) |
EP (1) | EP2295987B1 (ja) |
JP (1) | JP5274124B2 (ja) |
CN (1) | CN102084257B (ja) |
ES (1) | ES2608063T3 (ja) |
WO (1) | WO2010001644A1 (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5295069B2 (ja) * | 2009-10-09 | 2013-09-18 | ベックマン コールター, インコーポレイテッド | 分注装置、分析装置、および分注方法 |
JP5772886B2 (ja) * | 2013-06-26 | 2015-09-02 | 東亜ディーケーケー株式会社 | 分析装置 |
JP6204104B2 (ja) * | 2013-07-29 | 2017-09-27 | 株式会社堀場製作所 | 液体分析装置 |
JP6230450B2 (ja) * | 2014-03-10 | 2017-11-15 | 株式会社日立ハイテクノロジーズ | 分注装置及び分注方法 |
US10023333B2 (en) | 2016-03-07 | 2018-07-17 | The Procter & Gamble Company | Vacuum assisted nozzle and apparatus |
SG10202107223QA (en) * | 2017-02-17 | 2021-08-30 | Life Technologies Corp | Automated quality control and spectral error correction for sample analysis instruments |
JP7374679B2 (ja) * | 2019-09-11 | 2023-11-07 | キヤノン株式会社 | インプリント装置およびインプリント装置の制御方法 |
CN114160224B (zh) * | 2021-10-22 | 2022-12-06 | 成都开图医疗系统科技有限公司 | 一种微量加样器及加样方法 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE791890A (fr) * | 1971-11-26 | 1973-03-16 | Rohe Scientific Corp | Echantillonneur et dilueur |
US4244919A (en) * | 1979-03-19 | 1981-01-13 | Hyperion Incorporated | Sample diluting apparatus |
US4277440A (en) * | 1979-07-02 | 1981-07-07 | Eastman Kodak Company | Metering apparatus |
JPS6064256A (ja) * | 1983-09-19 | 1985-04-12 | Hitachi Ltd | 自動分析装置用脱気処理装置 |
US4968485A (en) * | 1987-09-25 | 1990-11-06 | Shimadzu Corporation | Arrangements for preparative route leading to water analysis |
JPH0510959A (ja) * | 1991-07-04 | 1993-01-19 | Sanuki Kogyo Kk | 理化学機械用複液混合送液装置 |
US6203759B1 (en) * | 1996-05-31 | 2001-03-20 | Packard Instrument Company | Microvolume liquid handling system |
US6521187B1 (en) | 1996-05-31 | 2003-02-18 | Packard Instrument Company | Dispensing liquid drops onto porous brittle substrates |
GB9405028D0 (en) * | 1994-03-15 | 1994-04-27 | Counting Tech Ltd | Fluid diluter |
JPH08178806A (ja) * | 1994-10-28 | 1996-07-12 | Shimadzu Corp | 液体試料注入装置 |
US6083762A (en) * | 1996-05-31 | 2000-07-04 | Packard Instruments Company | Microvolume liquid handling system |
DE69727422T2 (de) * | 1996-05-31 | 2004-07-01 | Packard Instrument Co., Inc., Downers Grove | Vorrichtung zur Handhabung von Mikroflüssigkeitsmengen |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
JP3682138B2 (ja) | 1997-02-13 | 2005-08-10 | アロカ株式会社 | 分注装置 |
US6060320A (en) * | 1997-12-05 | 2000-05-09 | Bayer Corporation | Method of verifying aspirated volume in automatic diagnostic system |
US20020159919A1 (en) * | 1998-01-09 | 2002-10-31 | Carl Churchill | Method and apparatus for high-speed microfluidic dispensing using text file control |
US6551557B1 (en) * | 1998-07-07 | 2003-04-22 | Cartesian Technologies, Inc. | Tip design and random access array for microfluidic transfer |
JP3079429B2 (ja) * | 1999-01-26 | 2000-08-21 | サヌキ工業株式会社 | フローインジェクション分析装置 |
US20030207464A1 (en) * | 1999-02-19 | 2003-11-06 | Tony Lemmo | Methods for microfluidic aspirating and dispensing |
JP2000251689A (ja) * | 1999-02-26 | 2000-09-14 | Canon Inc | 電子放出素子の製造方法及びそれを用いた電子源基板、画像形成装置の製造方法及びその製造に用いる液滴付与装置 |
DE10002475C1 (de) * | 2000-01-21 | 2001-05-31 | Roche Diagnostics Gmbh | Analysegerät zur Analyse von Proben |
US6706245B2 (en) * | 2000-03-10 | 2004-03-16 | Teledyne Tekmar Company | Three stage needle for use with an autosampler |
JP2002001092A (ja) * | 2000-06-22 | 2002-01-08 | Shimadzu Corp | 排液装置 |
US20020142341A1 (en) | 2001-03-28 | 2002-10-03 | Makoto Kameyama | Method and apparatus for producing probe carrier |
JP4854124B2 (ja) * | 2001-03-28 | 2012-01-18 | キヤノン株式会社 | プローブ担体製造方法および装置 |
JP2004535572A (ja) * | 2001-06-13 | 2004-11-25 | ケニス エフ. ウーヘンハイマー, | 自動化流体操作システムおよび方法 |
US6579724B2 (en) * | 2001-09-13 | 2003-06-17 | First Ten Angstroms | Dispensing method and apparatus for dispensing very small quantities of fluid |
US7288228B2 (en) * | 2002-02-12 | 2007-10-30 | Gilson, Inc. | Sample injection system |
JP4248328B2 (ja) * | 2002-08-07 | 2009-04-02 | 株式会社日立ハイテクノロジーズ | サンプル分注装置およびそれを用いた自動分析装置 |
JP2004191256A (ja) * | 2002-12-12 | 2004-07-08 | Kawamura Inst Of Chem Res | マイクロ流体素子への試料導入方法 |
US7294309B1 (en) * | 2003-05-15 | 2007-11-13 | Takeda San Diego, Inc. | Small volume liquid handling apparatus and method |
JP2006343246A (ja) * | 2005-06-09 | 2006-12-21 | Olympus Corp | 分注装置および分析装置 |
JP2007245038A (ja) * | 2006-03-17 | 2007-09-27 | Ebara Corp | マイクロ流体デバイスにおける気泡除去装置及び方法 |
JP2007278833A (ja) | 2006-04-06 | 2007-10-25 | Olympus Corp | 分注装置における配管内の気泡の有無判定方法および分注装置 |
JP4753770B2 (ja) | 2006-04-06 | 2011-08-24 | ベックマン コールター, インコーポレイテッド | 分注装置における配管内の気泡の有無判定方法および分注装置 |
JP2007322318A (ja) | 2006-06-02 | 2007-12-13 | Olympus Corp | サンプル分注装置 |
-
2008
- 2008-07-02 JP JP2008173724A patent/JP5274124B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-19 CN CN200980125941.5A patent/CN102084257B/zh active Active
- 2009-03-19 WO PCT/JP2009/055505 patent/WO2010001644A1/ja active Application Filing
- 2009-03-19 US US13/001,776 patent/US8449840B2/en active Active
- 2009-03-19 EP EP09773222.6A patent/EP2295987B1/en active Active
- 2009-03-19 ES ES09773222.6T patent/ES2608063T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US8449840B2 (en) | 2013-05-28 |
ES2608063T3 (es) | 2017-04-05 |
US20110171744A1 (en) | 2011-07-14 |
EP2295987A4 (en) | 2013-03-06 |
WO2010001644A1 (ja) | 2010-01-07 |
CN102084257B (zh) | 2013-07-31 |
EP2295987A1 (en) | 2011-03-16 |
CN102084257A (zh) | 2011-06-01 |
EP2295987B1 (en) | 2016-10-05 |
JP2010014490A (ja) | 2010-01-21 |
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