ATE220538T1 - Ophthalmologische zusammensetzung, die ein ionenempfindliches polymer und ein anorganisches salz in einem verhältnis enthält, das eine niedrige viskosität ergibt - Google Patents
Ophthalmologische zusammensetzung, die ein ionenempfindliches polymer und ein anorganisches salz in einem verhältnis enthält, das eine niedrige viskosität ergibtInfo
- Publication number
- ATE220538T1 ATE220538T1 AT95914363T AT95914363T ATE220538T1 AT E220538 T1 ATE220538 T1 AT E220538T1 AT 95914363 T AT95914363 T AT 95914363T AT 95914363 T AT95914363 T AT 95914363T AT E220538 T1 ATE220538 T1 AT E220538T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- ion sensitive
- polymer
- composition containing
- low viscosity
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 3
- 229910017053 inorganic salt Inorganic materials 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9401109A SE9401109D0 (sv) | 1994-03-31 | 1994-03-31 | Opthalmic composition II |
| PCT/FI1995/000167 WO1995026712A1 (en) | 1994-03-31 | 1995-03-29 | Ophthalmic composition containing an ion sensitive, hydrophilic polymer and an inorganic salt in a ratio which gives low viscosity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE220538T1 true ATE220538T1 (de) | 2002-08-15 |
Family
ID=20393512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95914363T ATE220538T1 (de) | 1994-03-31 | 1995-03-29 | Ophthalmologische zusammensetzung, die ein ionenempfindliches polymer und ein anorganisches salz in einem verhältnis enthält, das eine niedrige viskosität ergibt |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5795913A (de) |
| EP (1) | EP0755246B1 (de) |
| JP (1) | JPH10503471A (de) |
| KR (1) | KR970702025A (de) |
| CN (1) | CN1114399C (de) |
| AT (1) | ATE220538T1 (de) |
| AU (1) | AU694498B2 (de) |
| BG (1) | BG63144B1 (de) |
| BR (1) | BR9507439A (de) |
| CA (1) | CA2186591A1 (de) |
| CZ (1) | CZ286496A3 (de) |
| DE (2) | DE69527422T2 (de) |
| DK (1) | DK0755246T3 (de) |
| EE (1) | EE03662B1 (de) |
| ES (1) | ES2179871T3 (de) |
| HU (1) | HU223070B1 (de) |
| MX (1) | MX9603919A (de) |
| NO (1) | NO314435B1 (de) |
| PL (1) | PL316585A1 (de) |
| PT (1) | PT755246E (de) |
| RO (1) | RO115410B1 (de) |
| RU (1) | RU2157194C2 (de) |
| SE (1) | SE9401109D0 (de) |
| SK (1) | SK281473B6 (de) |
| WO (1) | WO1995026712A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY116782A (en) | 1997-12-22 | 2004-03-31 | Otsuka Pharma Co Ltd | Water-soluble eye drop |
| WO2000064528A1 (en) | 1999-04-28 | 2000-11-02 | Situs Corporation | Drug delivery system |
| AT407482B (de) * | 1999-05-10 | 2001-03-26 | Armin Dr Ettl | Kalziumantagonistische augentropfen zur prophylaktischen behandlung der cataract |
| US6218428B1 (en) | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| WO2003072081A1 (en) * | 2002-02-22 | 2003-09-04 | Pharmacia Corporation | Ophthalmic formulation with gum system |
| US7030149B2 (en) | 2002-04-19 | 2006-04-18 | Allergan, Inc. | Combination of brimonidine timolol for topical ophthalmic use |
| US8877168B1 (en) | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| ATE528003T1 (de) | 2002-07-31 | 2011-10-15 | Senju Pharma Co | Wässrige, flüssigkeitszubereitungen und lichtstabilisierte wässrige flüssigkeitszubereitungen |
| US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
| US20080057022A1 (en) * | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
| IL212725A (en) | 2011-05-05 | 2016-06-30 | Resdevco Res And Dev Co | Glycerol Preparation for Non-surgical Conjunctivochalysis |
| ES2908479T3 (es) | 2015-08-26 | 2022-04-29 | Achillion Pharmaceuticals Inc | Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017197051A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Amine-linked c3-glutarimide degronimers for target protein degradation |
| AU2017275492A1 (en) * | 2016-06-01 | 2018-12-20 | Harold Richard Hellstrom | Treatment of dry eye disease with parasympathetic and anti-sympathetic agents |
| EP3939591A1 (de) | 2016-06-27 | 2022-01-19 | Achillion Pharmaceuticals, Inc. | Chinazolin- und indolverbindungen zur behandlung von medizinischen leiden |
| WO2018033792A2 (en) | 2016-08-19 | 2018-02-22 | Orasis Pharmaceuticals Ltd. | Ophthalmic pharmaceutical compositions and uses relating thereto |
| AU2018227849B2 (en) | 2017-03-01 | 2022-04-28 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| CN111902141A (zh) | 2018-03-26 | 2020-11-06 | C4医药公司 | 用于ikaros降解的羟脑苷脂结合剂 |
| HRP20220762T1 (hr) * | 2018-04-24 | 2022-09-16 | Allergan, Inc. | Upotreba pilokarpin-hidroklorida u liječenju prezbiopije |
| JP7538113B2 (ja) | 2018-08-20 | 2024-08-21 | アキリオン ファーマシューティカルズ，インコーポレーテッド | 補体ｄ因子の医学的障害の治療のための医薬化合物 |
| WO2020051532A2 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| WO2020081723A1 (en) | 2018-10-16 | 2020-04-23 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| KR20210152515A (ko) | 2019-04-12 | 2021-12-15 | 씨4 테라퓨틱스, 인코포레이티드 | 이카로스 및 아이올로스의 트리시클릭 분해제 |
| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
| MX2022010952A (es) | 2020-03-05 | 2022-10-07 | C4 Therapeutics Inc | Compuestos para la degradacion dirigida de brd9. |
| JP7787164B2 (ja) | 2020-09-23 | 2025-12-16 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 補体媒介性障害の治療のための医薬化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| GB2169508B (en) * | 1985-01-11 | 1989-02-01 | Smith & Nephew Ass | Ophthalmic compositions and use |
| US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| FR2678832B1 (fr) * | 1991-07-10 | 1995-03-17 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation. |
| RU2007152C1 (ru) * | 1992-10-01 | 1994-02-15 | Курский Государственный Медицинский Институт | Офтальмологическое средство и способ его получения |
-
1994
- 1994-03-31 SE SE9401109A patent/SE9401109D0/xx unknown
-
1995
- 1995-03-29 SK SK1238-96A patent/SK281473B6/sk unknown
- 1995-03-29 ES ES95914363T patent/ES2179871T3/es not_active Expired - Lifetime
- 1995-03-29 RU RU96119922/14A patent/RU2157194C2/ru not_active IP Right Cessation
- 1995-03-29 PT PT95914363T patent/PT755246E/pt unknown
- 1995-03-29 DK DK95914363T patent/DK0755246T3/da active
- 1995-03-29 KR KR1019960705392A patent/KR970702025A/ko not_active Withdrawn
- 1995-03-29 EP EP95914363A patent/EP0755246B1/de not_active Expired - Lifetime
- 1995-03-29 PL PL95316585A patent/PL316585A1/xx unknown
- 1995-03-29 EE EE9600157A patent/EE03662B1/xx not_active IP Right Cessation
- 1995-03-29 CN CN95192184A patent/CN1114399C/zh not_active Expired - Fee Related
- 1995-03-29 US US08/535,033 patent/US5795913A/en not_active Expired - Fee Related
- 1995-03-29 CA CA002186591A patent/CA2186591A1/en not_active Abandoned
- 1995-03-29 AT AT95914363T patent/ATE220538T1/de not_active IP Right Cessation
- 1995-03-29 AU AU21390/95A patent/AU694498B2/en not_active Ceased
- 1995-03-29 CZ CZ962864A patent/CZ286496A3/cs unknown
- 1995-03-29 JP JP7525424A patent/JPH10503471A/ja active Pending
- 1995-03-29 MX MX9603919A patent/MX9603919A/es not_active IP Right Cessation
- 1995-03-29 DE DE69527422T patent/DE69527422T2/de not_active Expired - Fee Related
- 1995-03-29 WO PCT/FI1995/000167 patent/WO1995026712A1/en not_active Ceased
- 1995-03-29 RO RO96-01878A patent/RO115410B1/ro unknown
- 1995-03-29 BR BR9507439A patent/BR9507439A/pt not_active IP Right Cessation
- 1995-03-29 DE DE0755246T patent/DE755246T1/de active Pending
- 1995-03-29 HU HU9602692A patent/HU223070B1/hu not_active IP Right Cessation
-
1996
- 1996-09-27 NO NO19964071A patent/NO314435B1/no unknown
- 1996-10-16 BG BG100914A patent/BG63144B1/bg unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0755246 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |