NO314435B1 - Lav-viskositets oftalmisk blanding - Google Patents
Lav-viskositets oftalmisk blanding Download PDFInfo
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- NO314435B1 NO314435B1 NO19964071A NO964071A NO314435B1 NO 314435 B1 NO314435 B1 NO 314435B1 NO 19964071 A NO19964071 A NO 19964071A NO 964071 A NO964071 A NO 964071A NO 314435 B1 NO314435 B1 NO 314435B1
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- 239000000203 mixture Substances 0.000 title claims abstract description 77
- 239000000243 solution Substances 0.000 claims abstract description 42
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- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims description 21
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- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 6
- 229960000454 timolol hemihydrate Drugs 0.000 claims description 6
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- 235000011008 sodium phosphates Nutrition 0.000 claims description 5
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 5
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 claims description 4
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- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 claims description 3
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 claims description 3
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- 239000001103 potassium chloride Substances 0.000 claims description 3
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- LWAFSWPYPHEXKX-UHFFFAOYSA-N carteolol Chemical compound N1C(=O)CCC2=C1C=CC=C2OCC(O)CNC(C)(C)C LWAFSWPYPHEXKX-UHFFFAOYSA-N 0.000 claims description 2
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- IXHBTMCLRNMKHZ-LBPRGKRZSA-N levobunolol Chemical compound O=C1CCCC2=C1C=CC=C2OC[C@@H](O)CNC(C)(C)C IXHBTMCLRNMKHZ-LBPRGKRZSA-N 0.000 claims description 2
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- 235000011083 sodium citrates Nutrition 0.000 claims description 2
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- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 claims description 2
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- CHDPSNLJFOQTRK-UHFFFAOYSA-N betaxolol hydrochloride Chemical compound [Cl-].C1=CC(OCC(O)C[NH2+]C(C)C)=CC=C1CCOCC1CC1 CHDPSNLJFOQTRK-UHFFFAOYSA-N 0.000 claims 1
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- SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 description 1
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- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9401109A SE9401109D0 (sv) | 1994-03-31 | 1994-03-31 | Opthalmic composition II |
| PCT/FI1995/000167 WO1995026712A1 (en) | 1994-03-31 | 1995-03-29 | Ophthalmic composition containing an ion sensitive, hydrophilic polymer and an inorganic salt in a ratio which gives low viscosity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964071D0 NO964071D0 (no) | 1996-09-27 |
| NO964071L NO964071L (no) | 1996-11-22 |
| NO314435B1 true NO314435B1 (no) | 2003-03-24 |
Family
ID=20393512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19964071A NO314435B1 (no) | 1994-03-31 | 1996-09-27 | Lav-viskositets oftalmisk blanding |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5795913A (de) |
| EP (1) | EP0755246B1 (de) |
| JP (1) | JPH10503471A (de) |
| KR (1) | KR970702025A (de) |
| CN (1) | CN1114399C (de) |
| AT (1) | ATE220538T1 (de) |
| AU (1) | AU694498B2 (de) |
| BG (1) | BG63144B1 (de) |
| BR (1) | BR9507439A (de) |
| CA (1) | CA2186591A1 (de) |
| CZ (1) | CZ286496A3 (de) |
| DE (2) | DE755246T1 (de) |
| DK (1) | DK0755246T3 (de) |
| EE (1) | EE03662B1 (de) |
| ES (1) | ES2179871T3 (de) |
| HU (1) | HU223070B1 (de) |
| MX (1) | MX9603919A (de) |
| NO (1) | NO314435B1 (de) |
| PL (1) | PL316585A1 (de) |
| PT (1) | PT755246E (de) |
| RO (1) | RO115410B1 (de) |
| RU (1) | RU2157194C2 (de) |
| SE (1) | SE9401109D0 (de) |
| SK (1) | SK281473B6 (de) |
| WO (1) | WO1995026712A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY116782A (en) * | 1997-12-22 | 2004-03-31 | Otsuka Pharma Co Ltd | Water-soluble eye drop |
| AU4808000A (en) | 1999-04-28 | 2000-11-10 | Situs Corporation | Drug delivery system |
| AT407482B (de) * | 1999-05-10 | 2001-03-26 | Armin Dr Ettl | Kalziumantagonistische augentropfen zur prophylaktischen behandlung der cataract |
| US6218428B1 (en) | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| TW200400055A (en) * | 2002-02-22 | 2004-01-01 | Pharmacia Corp | Ophthalmic formulation with novel gum composition |
| US7030149B2 (en) | 2002-04-19 | 2006-04-18 | Allergan, Inc. | Combination of brimonidine timolol for topical ophthalmic use |
| EP1525884B1 (de) * | 2002-07-31 | 2011-10-12 | Senju Pharmaceutical Co., Ltd. | Wässrige, flüssigkeitszubereitungen und lichtstabilisierte wässrige flüssigkeitszubereitungen |
| US8877168B1 (en) | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
| US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
| US20080057022A1 (en) * | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
| IL212725A (en) * | 2011-05-05 | 2016-06-30 | Resdevco Res And Dev Co | Glycerol Preparation for Non-surgical Conjunctivochalysis |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| CN109414431A (zh) * | 2016-06-01 | 2019-03-01 | 哈罗德·理查德·赫尔斯特伦 | 用副交感神经剂和抗交感神经剂治疗干眼病 |
| ES2902006T3 (es) | 2016-06-27 | 2022-03-24 | Achillion Pharmaceuticals Inc | Quinazolina y compuestos indol para tratar trastornos médicos |
| AU2017311636B2 (en) | 2016-08-19 | 2023-08-10 | Orasis Pharmaceuticals Ltd. | Ophthalmic pharmaceutical compositions and uses relating thereto |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー４ セラピューティクス， インコーポレイテッド | Ｉｋａｒｏｓの分解のためのセレブロン結合剤 |
| RS63360B1 (sr) * | 2018-04-24 | 2022-07-29 | Allergan Inc | Upotreba pilokarpin hidrohlorida u lečenju prezbiopije |
| WO2020041301A1 (en) | 2018-08-20 | 2020-02-27 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| WO2020081723A1 (en) | 2018-10-16 | 2020-04-23 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| BR112022017393A2 (pt) | 2020-03-05 | 2022-10-18 | C4 Therapeutics Inc | Composto, composição farmacêutica, método para tratar um transtorno mediado por brd9, e, uso de um composto |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| FR2678832B1 (fr) * | 1991-07-10 | 1995-03-17 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation. |
-
1994
- 1994-03-31 SE SE9401109A patent/SE9401109D0/xx unknown
-
1995
- 1995-03-29 US US08/535,033 patent/US5795913A/en not_active Expired - Fee Related
- 1995-03-29 EP EP95914363A patent/EP0755246B1/de not_active Expired - Lifetime
- 1995-03-29 MX MX9603919A patent/MX9603919A/es not_active IP Right Cessation
- 1995-03-29 JP JP7525424A patent/JPH10503471A/ja active Pending
- 1995-03-29 DE DE0755246T patent/DE755246T1/de active Pending
- 1995-03-29 AU AU21390/95A patent/AU694498B2/en not_active Ceased
- 1995-03-29 DE DE69527422T patent/DE69527422T2/de not_active Expired - Fee Related
- 1995-03-29 CZ CZ962864A patent/CZ286496A3/cs unknown
- 1995-03-29 RO RO96-01878A patent/RO115410B1/ro unknown
- 1995-03-29 KR KR1019960705392A patent/KR970702025A/ko not_active Application Discontinuation
- 1995-03-29 HU HU9602692A patent/HU223070B1/hu not_active IP Right Cessation
- 1995-03-29 CA CA002186591A patent/CA2186591A1/en not_active Abandoned
- 1995-03-29 ES ES95914363T patent/ES2179871T3/es not_active Expired - Lifetime
- 1995-03-29 PL PL95316585A patent/PL316585A1/xx unknown
- 1995-03-29 SK SK1238-96A patent/SK281473B6/sk unknown
- 1995-03-29 RU RU96119922/14A patent/RU2157194C2/ru not_active IP Right Cessation
- 1995-03-29 DK DK95914363T patent/DK0755246T3/da active
- 1995-03-29 AT AT95914363T patent/ATE220538T1/de not_active IP Right Cessation
- 1995-03-29 CN CN95192184A patent/CN1114399C/zh not_active Expired - Fee Related
- 1995-03-29 PT PT95914363T patent/PT755246E/pt unknown
- 1995-03-29 WO PCT/FI1995/000167 patent/WO1995026712A1/en active IP Right Grant
- 1995-03-29 BR BR9507439A patent/BR9507439A/pt not_active IP Right Cessation
- 1995-03-29 EE EE9600157A patent/EE03662B1/xx not_active IP Right Cessation
-
1996
- 1996-09-27 NO NO19964071A patent/NO314435B1/no unknown
- 1996-10-16 BG BG100914A patent/BG63144B1/bg unknown
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