EE03662B1 - Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse - Google Patents

Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse

Info

Publication number
EE03662B1
EE03662B1 EE9600157A EE9600157A EE03662B1 EE 03662 B1 EE03662 B1 EE 03662B1 EE 9600157 A EE9600157 A EE 9600157A EE 9600157 A EE9600157 A EE 9600157A EE 03662 B1 EE03662 B1 EE 03662B1
Authority
EE
Estonia
Prior art keywords
composition
pct
ratio
hydrophilic polymer
ion
Prior art date
Application number
EE9600157A
Other languages
English (en)
Estonian (et)
Other versions
EE9600157A (et
Inventor
Lehmussaari Kari
Vartiainen Eija
Reunam�ki Timo
Oksala Olli
Alaranta Sakari
Pohjala Esko
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of EE9600157A publication Critical patent/EE9600157A/xx
Publication of EE03662B1 publication Critical patent/EE03662B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9600157A 1994-03-31 1995-03-29 Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse EE03662B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401109A SE9401109D0 (sv) 1994-03-31 1994-03-31 Opthalmic composition II
PCT/FI1995/000167 WO1995026712A1 (en) 1994-03-31 1995-03-29 Ophthalmic composition containing an ion sensitive, hydrophilic polymer and an inorganic salt in a ratio which gives low viscosity

Publications (2)

Publication Number Publication Date
EE9600157A EE9600157A (et) 1997-06-16
EE03662B1 true EE03662B1 (et) 2002-04-15

Family

ID=20393512

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600157A EE03662B1 (et) 1994-03-31 1995-03-29 Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse

Country Status (25)

Country Link
US (1) US5795913A (de)
EP (1) EP0755246B1 (de)
JP (1) JPH10503471A (de)
KR (1) KR970702025A (de)
CN (1) CN1114399C (de)
AT (1) ATE220538T1 (de)
AU (1) AU694498B2 (de)
BG (1) BG63144B1 (de)
BR (1) BR9507439A (de)
CA (1) CA2186591A1 (de)
CZ (1) CZ286496A3 (de)
DE (2) DE755246T1 (de)
DK (1) DK0755246T3 (de)
EE (1) EE03662B1 (de)
ES (1) ES2179871T3 (de)
HU (1) HU223070B1 (de)
MX (1) MX9603919A (de)
NO (1) NO314435B1 (de)
PL (1) PL316585A1 (de)
PT (1) PT755246E (de)
RO (1) RO115410B1 (de)
RU (1) RU2157194C2 (de)
SE (1) SE9401109D0 (de)
SK (1) SK281473B6 (de)
WO (1) WO1995026712A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY116782A (en) * 1997-12-22 2004-03-31 Otsuka Pharma Co Ltd Water-soluble eye drop
AU4808000A (en) 1999-04-28 2000-11-10 Situs Corporation Drug delivery system
AT407482B (de) * 1999-05-10 2001-03-26 Armin Dr Ettl Kalziumantagonistische augentropfen zur prophylaktischen behandlung der cataract
US6218428B1 (en) 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
TW200400055A (en) * 2002-02-22 2004-01-01 Pharmacia Corp Ophthalmic formulation with novel gum composition
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
EP1525884B1 (de) * 2002-07-31 2011-10-12 Senju Pharmaceutical Co., Ltd. Wässrige, flüssigkeitszubereitungen und lichtstabilisierte wässrige flüssigkeitszubereitungen
US8877168B1 (en) 2002-07-31 2014-11-04 Senju Pharmaceuticals Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
DE102005035986B4 (de) * 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
IL212725A (en) * 2011-05-05 2016-06-30 Resdevco Res And Dev Co Glycerol Preparation for Non-surgical Conjunctivochalysis
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
CN109414431A (zh) * 2016-06-01 2019-03-01 哈罗德·理查德·赫尔斯特伦 用副交感神经剂和抗交感神经剂治疗干眼病
ES2902006T3 (es) 2016-06-27 2022-03-24 Achillion Pharmaceuticals Inc Quinazolina y compuestos indol para tratar trastornos médicos
AU2017311636B2 (en) 2016-08-19 2023-08-10 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
JP2021519337A (ja) 2018-03-26 2021-08-10 シー４ セラピューティクス， インコーポレイテッド Ｉｋａｒｏｓの分解のためのセレブロン結合剤
RS63360B1 (sr) * 2018-04-24 2022-07-29 Allergan Inc Upotreba pilokarpin hidrohlorida u lečenju prezbiopije
WO2020041301A1 (en) 2018-08-20 2020-02-27 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
WO2020081723A1 (en) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders
BR112022017393A2 (pt) 2020-03-05 2022-10-18 C4 Therapeutics Inc Composto, composição farmacêutica, método para tratar um transtorno mediado por brd9, e, uso de um composto

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056684B2 (ja) * 1977-11-07 1985-12-11 東興薬品工業株式会社 点眼剤
US5252318A (en) * 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
FR2678832B1 (fr) * 1991-07-10 1995-03-17 Europhta Sa Laboratoire Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation.

Also Published As

Publication number Publication date
SK123896A3 (en) 1997-06-04
CN1144476A (zh) 1997-03-05
ES2179871T3 (es) 2003-02-01
CN1114399C (zh) 2003-07-16
HU9602692D0 (en) 1996-11-28
AU694498B2 (en) 1998-07-23
BG100914A (en) 1997-07-31
DE755246T1 (de) 1997-09-04
CA2186591A1 (en) 1995-10-12
DE69527422T2 (de) 2003-03-20
WO1995026712A1 (en) 1995-10-12
DE69527422D1 (de) 2002-08-22
SE9401109D0 (sv) 1994-03-31
DK0755246T3 (da) 2002-11-04
NO964071D0 (no) 1996-09-27
ATE220538T1 (de) 2002-08-15
US5795913A (en) 1998-08-18
RU2157194C2 (ru) 2000-10-10
BG63144B1 (bg) 2001-05-31
MX9603919A (es) 1997-04-30
RO115410B1 (ro) 2000-02-28
EE9600157A (et) 1997-06-16
EP0755246B1 (de) 2002-07-17
NO964071L (no) 1996-11-22
EP0755246A1 (de) 1997-01-29
CZ286496A3 (en) 1997-03-12
AU2139095A (en) 1995-10-23
KR970702025A (ko) 1997-05-13
PL316585A1 (en) 1997-01-20
BR9507439A (pt) 1997-09-16
NO314435B1 (no) 2003-03-24
HUT75664A (en) 1997-05-28
SK281473B6 (sk) 2001-04-09
HU223070B1 (hu) 2004-03-01
JPH10503471A (ja) 1998-03-31
PT755246E (pt) 2002-11-29

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

MM4A Lapsed by not paying the annual fees

Effective date: 20060329