ATE196089T1 - Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen - Google Patents

Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen

Info

Publication number
ATE196089T1
ATE196089T1 AT95105774T AT95105774T ATE196089T1 AT E196089 T1 ATE196089 T1 AT E196089T1 AT 95105774 T AT95105774 T AT 95105774T AT 95105774 T AT95105774 T AT 95105774T AT E196089 T1 ATE196089 T1 AT E196089T1
Authority
AT
Austria
Prior art keywords
fucanes
inhibiting
agent
complement system
brown algae
Prior art date
Application number
AT95105774T
Other languages
English (en)
Inventor
Sylvia Colliec
Jacqueline Bretaudiere
Patrick Durand
Anne-Marie Fischer
Jacqueline Jozefonvicz
Bernard Kloareg
Catherine Vidal
Original Assignee
Ifremer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ifremer filed Critical Ifremer
Application granted granted Critical
Publication of ATE196089T1 publication Critical patent/ATE196089T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
AT95105774T 1989-06-14 1990-06-13 Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen ATE196089T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8907857A FR2648463B1 (fr) 1989-06-14 1989-06-14 Polysaccharides sulfates, agent anticoagulant et agent anticomplementaire obtenus a partir de fucanes d'algues brunes et leur procede d'obtention

Publications (1)

Publication Number Publication Date
ATE196089T1 true ATE196089T1 (de) 2000-09-15

Family

ID=9382699

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90401636T ATE131176T1 (de) 1989-06-14 1990-06-13 Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung.
AT95105774T ATE196089T1 (de) 1989-06-14 1990-06-13 Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT90401636T ATE131176T1 (de) 1989-06-14 1990-06-13 Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung.

Country Status (13)

Country Link
US (1) US5321133A (de)
EP (2) EP0676207B1 (de)
JP (1) JP3042543B2 (de)
CN (1) CN1051564A (de)
AT (2) ATE131176T1 (de)
AU (1) AU5841090A (de)
DD (1) DD296937A5 (de)
DE (2) DE69023957T2 (de)
ES (1) ES2152998T3 (de)
FR (1) FR2648463B1 (de)
IE (1) IE902153A1 (de)
PT (1) PT94359A (de)
WO (1) WO1990015823A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059679C (zh) * 1993-06-18 2000-12-20 青岛海洋大学 制备藻酸双酯钠的方法
RU2193039C2 (ru) * 1995-04-28 2002-11-20 Такара Сузо Ко., Лтд. Соединение сахара
FR2738009B1 (fr) * 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
CA2243543A1 (en) * 1996-01-26 1997-07-31 Research Institute For Glycotechnology Apoptosis inducers
EP0884383A4 (de) * 1996-02-29 2001-12-05 Takara Shuzo Co Methode zum reinigen und entfernen von viren.
IT1288713B1 (it) * 1996-12-18 1998-09-23 Crinos Industria Farmaco Fucani a basso peso molecolare aventi attivita' anticoagulante antitrombinica e antitrombotica
FR2772618B1 (fr) * 1997-12-18 2000-02-18 Ifremer Utilisation de fucane comme regulateur de la reconstruction des tissus conjonctifs
CN1263772C (zh) * 1998-02-17 2006-07-12 宝生物工程株式会社 硫酸糖
FR2797768B1 (fr) * 1999-09-01 2003-06-13 Ifremer Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire
CN1108310C (zh) * 1999-11-30 2003-05-14 中国科学院南海海洋研究所 一种海藻多糖及其制备方法和用途
KR100369518B1 (ko) * 2000-02-02 2003-01-30 김공수 저분자 다당류의 제조방법
US20040097464A1 (en) * 2000-09-11 2004-05-20 Ladislas Robert Mixture of non-sulfated fucose-based oligosaccharides, a cosmetic or pharmaceutical composition comprising said mixture and its use in cosmetics or pharmacy
CA2424830C (en) * 2000-09-11 2011-06-28 Industria E Comercio De Cosmeticos Natura Ltda. Composition comprising fucose and vitamin c and/or vitamin a
US6812220B2 (en) * 2001-08-29 2004-11-02 University Of British Columbia Pharmaceutical compositions and methods relating to fucans
DE60202427T2 (de) * 2001-10-24 2005-12-29 Takara Bio Inc., Otsu Sulfatiertes Fucan-Oligosaccharid
JP4262601B2 (ja) * 2002-01-18 2009-05-13 タカラバイオ株式会社 硫酸化フカン
US6797705B2 (en) * 2002-12-16 2004-09-28 Endomatrix, Inc. Rhamnan sulphate composition for treatment of endothelial dysfunction
US20040208893A1 (en) * 2002-12-16 2004-10-21 Daniels Bruce Alan Seaweed extract composition for treatment of diabetes and diabetic complications
WO2005095427A1 (ja) * 2004-04-02 2005-10-13 Takara Bio Inc. 血栓症の予防又は治療のための組成物
FR2881051A1 (fr) * 2005-01-27 2006-07-28 Therapol Sa Utilisation de fucanes selectionnes pour la preparation d'un materiau bacteriophobe et bacteriostatique, materiau correspondant et applications
FR2882258B1 (fr) * 2005-02-22 2009-01-16 Oreal Utilisation capillaire de polysaccharides sulfates
KR100729638B1 (ko) 2005-05-20 2007-06-19 배태진 미역포자엽으로부터 분리한 항혈액응고활성을 가진황산화푸코스다당 및 그 제조방법
WO2007028256A2 (en) 2005-09-09 2007-03-15 Les Biotechnologies Oceanova Inc. Polysaccharides compositions comprising fucans and galactans and their use to reduce extravasation and inflammation
FR2897538B1 (fr) 2006-02-23 2008-05-02 Univ Paris Descartes Utilisation de fucanes a des fins de greffe, d'ingenierie et de regeneration osseuses
CN101168570B (zh) * 2007-11-15 2010-05-26 暨南大学 海带硫酸多糖的降解方法
JP4428486B1 (ja) * 2008-10-28 2010-03-10 国立大学法人鳥取大学 線溶賦活剤
WO2010086696A1 (en) 2009-01-28 2010-08-05 Therapol Low-molecular-weight sulphated polysaccharides as candidates for anti-angiogenic therapy
US20120093725A1 (en) 2009-04-10 2012-04-19 Inserm (Institut National De La Sante Et De La Recherche Medicale Fucoidans as Ligands for the Diagnosis of Degenerative Pathologies
WO2014068601A1 (en) * 2012-10-29 2014-05-08 Matis Ohf. Use of natural antioxidants during enzymatic hydrolysis of aquatic protein to obtain high quality aquatic protein hydrolysates
WO2014147597A1 (en) 2013-03-21 2014-09-25 Institut National De La Sante Et De La Recherche Medicale Aminofucoidan as a vector for fibrinolysis in thrombotic diseases
FR3047179B1 (fr) * 2016-01-29 2019-10-25 Seprosys Ulvanes sulfates et utilisation dans la regulation des troubles de la coagulation
MX2020002288A (es) 2016-08-31 2020-07-14 Oji Holdings Corp Metodo de produccion para xilooligosacarido acido y xilooligosacarido acido.
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
FR3055549A1 (fr) * 2016-09-02 2018-03-09 Universite Blaise Pascal-Clermont-Ferrand Ii Polysaccharide sulfate extrait d'une algue rouge pour son utilisation en tant qu'anticoagulant
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
MX2019014445A (es) 2017-05-31 2020-02-10 Oji Holdings Corp Preparacion hidratante topica.
WO2019054344A1 (ja) * 2017-09-12 2019-03-21 王子ホールディングス株式会社 ポリ硫酸ペントサン及びポリ硫酸ペントサンの製造方法
US11344570B2 (en) 2017-12-20 2022-05-31 Oji Holdings Corporation Pentosan polysulfate and medicine containing pentosan polysulfate
FR3079831B1 (fr) 2018-04-05 2020-11-20 Jymsea Procede d’extraction d’oligofucanes et ses applications
CN110632188A (zh) * 2019-08-19 2019-12-31 中国石油天然气股份有限公司 酚醛凝胶含量的测试方法
EP4161579A1 (de) 2020-06-09 2023-04-12 Institut National de la Santé et de la Recherche Médicale (INSERM) Fucoidanfunktionalisierte polysaccharidpartikel mit t-pa zur gezielten thrombolytischen therapie
FR3113236A1 (fr) 2020-08-05 2022-02-11 Algues Et Mer Fraction purifiée de fucoïdanes pour la préparation de compositions cosmétiques et/ou dermatologiques anti-age.
CN115386013B (zh) * 2022-04-19 2023-05-12 广西中医药大学 一种具有强效抗凝活性的海带多糖及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB890207A (en) * 1957-03-07 1962-02-28 Ciba Ltd Extraction of a new polysaccharide substance from crude fucoidin
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
FR2513122A1 (fr) * 1981-09-23 1983-03-25 Goemar Sa Nouveaux medicaments a base d'extraits d'algues, et formulations correspondantes

Also Published As

Publication number Publication date
EP0403377A1 (de) 1990-12-19
FR2648463B1 (fr) 1993-01-22
EP0676207B1 (de) 2000-09-06
JP3042543B2 (ja) 2000-05-15
US5321133A (en) 1994-06-14
ATE131176T1 (de) 1995-12-15
FR2648463A1 (fr) 1990-12-21
CN1051564A (zh) 1991-05-22
EP0403377B1 (de) 1995-12-06
JPH04506089A (ja) 1992-10-22
DE69023957T2 (de) 1996-07-04
WO1990015823A1 (fr) 1990-12-27
DE69023957D1 (de) 1996-01-18
DE69033626T2 (de) 2001-05-23
DD296937A5 (de) 1991-12-19
EP0676207A3 (de) 1995-11-08
EP0676207A2 (de) 1995-10-11
ES2152998T3 (es) 2001-02-16
AU5841090A (en) 1991-01-08
IE902153A1 (en) 1991-01-02
IE902153L (en) 1990-12-14
PT94359A (pt) 1991-02-08
DE69033626D1 (de) 2000-10-12

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