US6008217A
(en)
*
|
1995-12-20 |
1999-12-28 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5874424A
(en)
*
|
1995-12-20 |
1999-02-23 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US6204261B1
(en)
*
|
1995-12-20 |
2001-03-20 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β Converting enzyme inhibitors
|
US5328988A
(en)
*
|
1987-10-26 |
1994-07-12 |
Immunex Corporation |
Interleukin-7
|
US5714585A
(en)
*
|
1987-10-26 |
1998-02-03 |
Sterling Winthrop, Inc. |
Antibodies that are immunoreactive with interleukin-7
|
US6511665B1
(en)
*
|
1987-11-25 |
2003-01-28 |
Immunex Corporation |
Antibodies to interleukin-1 receptors
|
US6858409B1
(en)
|
1988-05-27 |
2005-02-22 |
Amgen Inc. |
Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
|
US5075222A
(en)
|
1988-05-27 |
1991-12-24 |
Synergen, Inc. |
Interleukin-1 inhibitors
|
US6159460A
(en)
*
|
1988-05-27 |
2000-12-12 |
Amgen Inc. |
Method for treating interleukin-1 mediated diseases
|
JP3039802B2
(ja)
|
1989-07-06 |
2000-05-08 |
ザ リージェンツ オブザ ユニバーシティ オブ カリフォルニア |
繊維芽細胞成長因子のための受容体
|
US5106965A
(en)
*
|
1989-11-27 |
1992-04-21 |
Research Corporation Technologies, Inc. |
Detection of human adenovirus
|
US5470730A
(en)
*
|
1990-09-28 |
1995-11-28 |
Immunex |
Method for producing TH -independent cytotoxic T lymphocytes
|
CA2092548A1
(en)
*
|
1990-09-28 |
1992-03-29 |
Philip D. Greenberg |
Method for producing th-independent cytotoxic t lymphocytes
|
US6159464A
(en)
*
|
1990-12-20 |
2000-12-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
|
US6156304A
(en)
*
|
1990-12-20 |
2000-12-05 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Gene transfer for studying and treating a connective tissue of a mammalian host
|
US6413511B1
(en)
|
1990-12-20 |
2002-07-02 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
|
WO1992011359A1
(en)
*
|
1990-12-20 |
1992-07-09 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
A truncated interleukin-1 receptor gene for the treatment of arthritis
|
US6228356B1
(en)
|
1990-12-20 |
2001-05-08 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints
|
US5858355A
(en)
*
|
1990-12-20 |
1999-01-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
IRAP gene as treatment for arthritis
|
US5770401A
(en)
*
|
1991-10-15 |
1998-06-23 |
Mullarkey; Michael F. |
Methods and compositions for treating allergic reactions
|
NZ251820A
(en)
*
|
1992-03-30 |
1996-07-26 |
Immunex Corp |
Fusion proteins with tnf-r (tumour necrosis factor-receptor) peptide linked to another tnf-r or an il-1r (interleukin-1-receptor) peptide
|
US6582728B1
(en)
|
1992-07-08 |
2003-06-24 |
Inhale Therapeutic Systems, Inc. |
Spray drying of macromolecules to produce inhaleable dry powders
|
US6509006B1
(en)
|
1992-07-08 |
2003-01-21 |
Inhale Therapeutic Systems, Inc. |
Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
|
US7448375B2
(en)
|
1993-01-29 |
2008-11-11 |
Aradigm Corporation |
Method of treating diabetes mellitus in a patient
|
US6024090A
(en)
|
1993-01-29 |
2000-02-15 |
Aradigm Corporation |
Method of treating a diabetic patient by aerosolized administration of insulin lispro
|
US5861476A
(en)
*
|
1994-02-02 |
1999-01-19 |
Affymax Technologies N.V. |
Peptides and compounds that bind to the IL-1 receptor
|
US5608035A
(en)
*
|
1994-02-02 |
1997-03-04 |
Affymax Technologies N.V. |
Peptides and compounds that bind to the IL-1 receptor
|
US5786331A
(en)
*
|
1994-02-02 |
1998-07-28 |
Affymax Technologies N.V. |
Peptides and compounds that bind to the IL-1 receptor
|
US5880096A
(en)
*
|
1994-02-02 |
1999-03-09 |
Affymax Technologies N.V. |
Peptides and compounds that bind to the IL-1 receptor
|
US6051256A
(en)
|
1994-03-07 |
2000-04-18 |
Inhale Therapeutic Systems |
Dispersible macromolecule compositions and methods for their preparation and use
|
PL179443B1
(pl)
*
|
1994-03-07 |
2000-09-29 |
Inhale Therapeutic Syst |
Kompozycja insuliny, sposób wytwarzania kompozycji insuliny i sposób wytwarzania dawki insuliny w postaci aerozolu PL PL PL PL
|
JPH083058A
(ja)
*
|
1994-06-17 |
1996-01-09 |
Hoechst Japan Ltd |
新規な骨代謝疾患治療剤
|
US6420522B1
(en)
*
|
1995-06-05 |
2002-07-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5847135A
(en)
*
|
1994-06-17 |
1998-12-08 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5716929A
(en)
*
|
1994-06-17 |
1998-02-10 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1β converting enzyme
|
US5756466A
(en)
*
|
1994-06-17 |
1998-05-26 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1β converting enzyme
|
US6239268B1
(en)
|
1994-09-09 |
2001-05-29 |
Neurocrine Biosciences, Inc. |
Interleukin-1 type 3 receptors
|
AU705595B2
(en)
*
|
1994-09-09 |
1999-05-27 |
Neurocrine Biosciences, Incorporated |
Interleukin-1 type 3 receptors
|
US7091181B2
(en)
|
1994-12-12 |
2006-08-15 |
Omeros Corporation |
Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
|
US5780014A
(en)
*
|
1995-04-14 |
1998-07-14 |
Inhale Therapeutic Systems |
Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
|
CA2225378C
(en)
|
1995-06-29 |
2012-04-17 |
Immunex Corporation |
Cytokine that induces apoptosis
|
US5843904A
(en)
*
|
1995-12-20 |
1998-12-01 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1βconverting enzyme
|
US6410252B1
(en)
|
1995-12-22 |
2002-06-25 |
Case Western Reserve University |
Methods for measuring T cell cytokines
|
US5939281A
(en)
*
|
1996-09-16 |
1999-08-17 |
Case Western Reserve University |
Detecting alloreactivity
|
JP4771563B2
(ja)
|
1996-12-06 |
2011-09-14 |
アムジエン・インコーポレーテツド |
Il−1媒介疾患を処置するためにil−1インヒビターを使用する組合せ療法
|
US20030203036A1
(en)
|
2000-03-17 |
2003-10-30 |
Gordon Marc S. |
Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
|
US6294170B1
(en)
|
1997-08-08 |
2001-09-25 |
Amgen Inc. |
Composition and method for treating inflammatory diseases
|
US6524795B1
(en)
|
1997-03-10 |
2003-02-25 |
Interleukin Genetics, Inc. |
Diagnostics for cardiovascular disorders
|
US7820383B2
(en)
*
|
1997-03-10 |
2010-10-26 |
Interleukin Genetics, Inc. |
Method for diagnosing myocardial infarction
|
US6384203B1
(en)
|
1999-05-12 |
2002-05-07 |
Immunex Corporation |
Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
|
US6063600A
(en)
*
|
1997-05-23 |
2000-05-16 |
Uab Research Foundation |
DNA encoding canine interleukin-1 receptor antagonist
|
US6733967B1
(en)
|
1998-04-21 |
2004-05-11 |
Interleukin Genetics, Inc. |
Fetal testing for prediction of low birth weight
|
WO2000011174A1
(en)
*
|
1998-08-21 |
2000-03-02 |
Immunex Corporation |
Human il-1 epsilon dna and polypeptides
|
AU1345000A
(en)
*
|
1998-11-05 |
2000-05-22 |
Omeros Medical Systems, Inc. |
Irrigation solution and method for inhibition of pain and inflammation
|
US20090023147A1
(en)
*
|
1999-08-30 |
2009-01-22 |
Kenneth Kornman |
Diagnostics and therapeutics for osteoporosis
|
US6346247B1
(en)
|
1999-10-28 |
2002-02-12 |
Promega Corporation |
Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
CA2394015C
(en)
|
1999-12-20 |
2013-11-05 |
Immunex Corporation |
Tweak receptor
|
AR030554A1
(es)
|
2000-03-16 |
2003-08-27 |
Amgen Inc |
Moleculas similares a receptores il-17 y usos de las mismas
|
EP1712239A3
(de)
*
|
2000-05-12 |
2007-08-22 |
Immunex Corporation |
Interleukin-1 Inhibitoren zur Behandlung von Erkrankungen
|
US7575761B2
(en)
|
2000-06-30 |
2009-08-18 |
Novartis Pharma Ag |
Spray drying process control of drying kinetics
|
US20030040119A1
(en)
*
|
2001-04-11 |
2003-02-27 |
The Regents Of The University Of Michigan |
Separation devices and methods for separating particles
|
US20050152902A1
(en)
*
|
2001-06-05 |
2005-07-14 |
Advanced Biotherapy, Inc. |
Treatment of diabetic retinopathy
|
CA2450809A1
(en)
*
|
2001-06-15 |
2002-12-27 |
Interleukin Genetics, Inc. |
Methods for detecting and treating the early onset of aging-related conditions
|
MXPA04000134A
(es)
|
2001-06-26 |
2005-06-06 |
Abgenix Inc |
Anticuerpos para ligandos de osteoprotegerina.
|
WO2003029436A2
(en)
|
2001-10-04 |
2003-04-10 |
Immunex Corporation |
Ul16 binding protein 4
|
US20080311581A1
(en)
*
|
2001-11-19 |
2008-12-18 |
David Wyllie |
Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
|
JP4492849B2
(ja)
*
|
2001-11-19 |
2010-06-30 |
インターリューキン ジェネティックス インコーポレイテッド |
転写および炎症性疾患および感染症に対する感受性に影響するインターロイキン−1遺伝子座の機能的多型
|
US20070264645A1
(en)
*
|
2002-01-25 |
2007-11-15 |
Kenneth Kornman |
IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
|
AU2003220529B2
(en)
|
2002-03-27 |
2006-09-07 |
Immunex Corporation |
Methods for increasing polypeptide production
|
GB0216562D0
(en)
|
2002-04-25 |
2002-08-28 |
Bradford Particle Design Ltd |
Particulate materials
|
US9339459B2
(en)
|
2003-04-24 |
2016-05-17 |
Nektar Therapeutics |
Particulate materials
|
BRPI0314038B8
(pt)
|
2002-09-06 |
2021-05-25 |
Amgen Inc |
anticorpo humano isolado, molécula de ácido nucleico isolada, vetor, uso de um anticorpo, e, composição farmacêutica
|
AU2003285874A1
(en)
|
2002-10-16 |
2004-05-04 |
Amgen Inc. |
HUMAN ANTI-IFN-Gamma NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-Gamma PATHWAY INHIBITORS
|
WO2004060911A2
(en)
|
2002-12-30 |
2004-07-22 |
Amgen Inc. |
Combination therapy with co-stimulatory factors
|
US20040254108A1
(en)
*
|
2003-06-13 |
2004-12-16 |
Jing Ma |
Preparation and application of anti-tumor bifunctional fusion proteins
|
US20050232931A1
(en)
*
|
2003-06-13 |
2005-10-20 |
Oncomax Acquisition Corp. |
Preparation and application of anti-tumor bifunctional fusion proteins
|
AU2004261941B2
(en)
|
2003-07-25 |
2008-04-10 |
Amgen Inc. |
Antagonists and agonists of LDCAM and methods of use
|
ATE490339T1
(de)
*
|
2003-08-08 |
2010-12-15 |
Interleukin Genetics Inc |
Diagnostikum für osteoporose
|
AU2005231822B2
(en)
*
|
2004-04-02 |
2011-07-21 |
Swedish Orphan Biovitrum Ab (Publ) |
Methods of reducing aggregation of IL-1ra
|
US20050276807A1
(en)
*
|
2004-06-15 |
2005-12-15 |
Advanced Biotherapy, Inc. |
Treatment of acne
|
WO2006044263A2
(en)
*
|
2004-10-12 |
2006-04-27 |
Advanced Biotherapy, Inc. |
Treatment of herpes
|
CN101133084A
(zh)
*
|
2004-12-02 |
2008-02-27 |
多曼蒂斯有限公司 |
采用白细胞介素-1ⅰ型受体拮抗剂治疗呼吸道疾病的方法
|
US8105775B2
(en)
*
|
2005-10-25 |
2012-01-31 |
Interleukin Genetics, Inc. |
IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
EP1957537A2
(de)
*
|
2005-12-01 |
2008-08-20 |
Domantis Limited |
Kompetitive domänenantikörperformate, die an den interleukin-1-rezeptor vom typ 1 binden
|
US8129334B2
(en)
|
2006-03-31 |
2012-03-06 |
The Regents Of The University Of California |
Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory
|
EP2500415A1
(de)
|
2006-09-13 |
2012-09-19 |
Abbott Laboratories |
Verbesserungen an Zellkulturen
|
SG10201510384UA
(en)
|
2006-09-13 |
2016-01-28 |
Abbvie Inc |
Cell culture improvements
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
ES2431671T3
(es)
*
|
2006-11-15 |
2013-11-27 |
Interleukin Genetics, Inc. |
El complejo génico de IL-1 y resistencia a la insulina: polimorfismos asociados, haplotipos y métodos para usarlos
|
SI2188313T1
(en)
|
2007-08-21 |
2018-04-30 |
Amgen, Inc. |
HUMAN C-FMS ANTIGEN TRANSFER PROTEIN
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
US20090170105A1
(en)
*
|
2007-11-08 |
2009-07-02 |
Interleukin Genetics, Inc. |
Diagnostics for Aging-Related Dermatologic Disorders
|
AU2009242490B2
(en)
|
2008-05-02 |
2015-01-22 |
Orig3N, Inc. |
Detecting genetic predisposition to osteoarthritis associated conditions
|
US20100129798A1
(en)
*
|
2008-05-02 |
2010-05-27 |
Interleukin Genetics, Inc. |
Detecting genetic predisposition to osteoarthritis associated conditions
|
EP3705135A1
(de)
|
2008-05-30 |
2020-09-09 |
XBiotech, Inc |
Il-1-alpha-abs und verfahren zur verwendung
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
JO3244B1
(ar)
|
2009-10-26 |
2018-03-08 |
Amgen Inc |
بروتينات ربط مستضادات il – 23 البشرية
|
EP2499165B1
(de)
|
2009-11-13 |
2016-09-14 |
Grifols Therapeutics Inc. |
Von-willebrand-faktor-haltige präparate, verfahren und kits dafür sowie verwendungen davon
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
US20130101590A1
(en)
|
2010-04-09 |
2013-04-25 |
Heather A. Arnett |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
CA2796055A1
(en)
|
2010-04-15 |
2011-10-20 |
Amgen Inc. |
Human fgf receptor and .beta.-klotho binding proteins
|
AU2011268229B2
(en)
|
2010-06-18 |
2015-04-16 |
Xbiotech Inc. |
Arthritis treatment
|
WO2012019160A1
(en)
|
2010-08-05 |
2012-02-09 |
Amgen Inc. |
Dipeptides to enhance yield and viability from cell cultures
|
SG187853A1
(en)
|
2010-08-23 |
2013-03-28 |
Xbiotech Inc |
Treatment for neoplastic diseases
|
US20140105898A1
(en)
|
2011-02-28 |
2014-04-17 |
Istituto Di Ricovero E Cura A Carattere Scientific Materno-Infantile Burlo Garo |
Apoptosis-inducing molecules and uses therefor
|
US9724409B2
(en)
|
2011-04-01 |
2017-08-08 |
Xbiotech, Inc. |
Treatment of inflammatory skin disease
|
WO2012145682A1
(en)
|
2011-04-21 |
2012-10-26 |
Amgen Inc. |
A method for culturing mammalian cells to improve recombinant protein production
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
CN103827292B
(zh)
|
2011-07-01 |
2018-01-26 |
安姆根有限公司 |
哺乳动物细胞培养
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
CA2840637A1
(en)
|
2011-09-02 |
2013-03-07 |
Amgen Inc. |
Pharmaceutical product and method of analysing light exposure of a pharmaceutical product
|
MY173865A
(en)
|
2011-09-22 |
2020-02-25 |
Amgen Inc |
Cd27l antigen binding proteins
|
CN104220460A
(zh)
|
2011-12-08 |
2014-12-17 |
安姆根有限公司 |
激动人lcat抗原结合蛋白和它们在疗法中的用途
|
AR089231A1
(es)
|
2011-12-15 |
2014-08-06 |
Amgen Inc |
Metodo de floculacion
|
SI3431492T1
(sl)
|
2012-04-27 |
2021-07-30 |
Novo Nordisk A/S |
Antigen-vezavni proteini liganda človeškega CD30
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
EP2875046B1
(de)
|
2012-07-19 |
2020-02-26 |
Amgen Inc. |
Humane btnl3-proteine, nukleinsäuren sowie antikörper und verwendungen davon
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
SG11201504482VA
(en)
|
2012-12-07 |
2015-07-30 |
Univ North Carolina State |
Beta-hexosyl-transferases and uses thereof
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
WO2014109858A1
(en)
|
2013-01-14 |
2014-07-17 |
Amgen Inc. |
Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
|
US9701743B2
(en)
|
2014-02-20 |
2017-07-11 |
Allergan, Inc. |
Complement component C5 antibodies
|
US10023608B1
(en)
|
2013-03-13 |
2018-07-17 |
Amgen Inc. |
Protein purification methods to remove impurities
|
EP2970451A1
(de)
|
2013-03-14 |
2016-01-20 |
Amgen Inc. |
Chrdl-1-antigenbindende proteine und behandlungsmethoden damit
|
TWI832345B
(zh)
|
2013-03-14 |
2024-02-11 |
美商安美基公司 |
用於增加重組蛋白質之甘露糖含量之方法
|
SI2969099T2
(sl)
|
2013-03-14 |
2022-04-29 |
Amgen Inc. |
Odstranjevanje izluženega afinitetnega purifikacijskega liganda
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
WO2014144632A2
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Human pac1 antibodies
|
WO2014151834A2
(en)
|
2013-03-15 |
2014-09-25 |
Amgen Inc. |
Methods and compositions relating to anti-ccr7 antigen binding proteins
|
WO2014144817A2
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Inhibitory polypeptides specific to wnt inhibitors
|
US9850297B2
(en)
|
2013-03-15 |
2017-12-26 |
Amgen Inc. |
Secreted frizzle-related protein 5 (SFRP5) binding proteins
|
ES2973474T3
(es)
|
2013-05-30 |
2024-06-20 |
Kiniksa Pharmaceuticals Ltd |
Proteínas de enlace a antígeno del receptor de oncostatina M
|
US9481901B2
(en)
|
2013-05-30 |
2016-11-01 |
Amgen Inc. |
Methods for increasing mannose content of recombinant proteins
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
MX2016002870A
(es)
|
2013-09-05 |
2017-02-23 |
Amgen Inc |
Moleculas que contienen fc que presentan perfiles de glicoforma predecibles, consistentes y reproducibles.
|
US20160257748A1
(en)
|
2013-09-25 |
2016-09-08 |
Amgen Inc. |
V-c-fc-v-c antibody
|
EP3063287A1
(de)
|
2013-10-31 |
2016-09-07 |
Amgen Inc. |
Verwendung von monensin zur regulierung der glycosylierung von rekombinanten proteinen
|
EP3094735A1
(de)
|
2014-01-13 |
2016-11-23 |
Amgen Inc. |
Regelung des ornithinmetabolismus zur manipulation des hohen mannoseglycoformgehalts rekombinanter proteine
|
US10106829B2
(en)
|
2014-01-29 |
2018-10-23 |
Amgen Inc. |
Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
|
KR102519540B1
(ko)
|
2014-01-29 |
2023-04-10 |
암젠 인크 |
재조합 단백질의 글리코실화를 조절하기 위한 n-글리코실화 경로 조절자의 과발현
|
WO2015130826A1
(en)
|
2014-02-27 |
2015-09-03 |
Allergan, Inc. |
COMPLEMENT FACTOR Bb ANTIBODIES
|
PL3152317T3
(pl)
|
2014-06-04 |
2019-08-30 |
Amgen Inc. |
Sposoby zbierania hodowli ssaczych komórek
|
MX2017003247A
(es)
|
2014-09-15 |
2017-11-30 |
Amgen Inc |
Proteina de union a antigenos, bi-especificos del receptor anti-cgrp/receptor pac1 y usos de las mismas.
|
US11275090B2
(en)
|
2014-11-19 |
2022-03-15 |
Amgen Inc. |
Quantitation of glycan moiety in recombinant glycoproteins
|
CA2969225C
(en)
|
2014-12-01 |
2023-08-22 |
Amgen Inc. |
Process for manipulating the level of glycan content of a glycoprotein
|
US10851144B2
(en)
|
2015-04-10 |
2020-12-01 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
JOP20200116A1
(ar)
|
2015-04-24 |
2017-06-16 |
Amgen Inc |
طرق لعلاج أو الوقاية من الصداع النصفي
|
JP6952605B2
(ja)
|
2015-04-24 |
2021-10-20 |
ジェネンテック, インコーポレイテッド |
多特異性抗原結合タンパク質
|
WO2017049004A1
(en)
|
2015-09-15 |
2017-03-23 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
KR102645625B1
(ko)
|
2015-09-22 |
2024-03-07 |
제넨테크, 인크. |
Fc-함유 단백질의 발현
|
EP3925970A1
(de)
|
2015-11-02 |
2021-12-22 |
F. Hoffmann-La Roche AG |
Verfahren zur herstellung von fucosylierten und afucosylierten formen eines proteins
|
WO2017106578A1
(en)
|
2015-12-15 |
2017-06-22 |
Amgen Inc. |
Pacap antibodies and uses thereof
|
WO2017112824A2
(en)
|
2015-12-23 |
2017-06-29 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
JP7422480B2
(ja)
|
2016-05-04 |
2024-01-26 |
アムジエン・インコーポレーテツド |
制御性t細胞の増殖のためのインターロイキン-2変異タンパク質
|
EP3487867A2
(de)
|
2016-07-22 |
2019-05-29 |
Amgen Inc. |
Verfahren zur reinigung von fc-haltigen proteinen
|
US10041044B2
(en)
|
2016-07-29 |
2018-08-07 |
Trustees Of Boston University |
Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
|
EP3538555A1
(de)
|
2016-11-14 |
2019-09-18 |
Amgen Inc. |
Bispezifische oder biparatopische antigenbindende proteine und verwendungen davon
|
WO2018128454A1
(ko)
|
2017-01-06 |
2018-07-12 |
에이비엘바이오 주식회사 |
항 α-SYN 항체 및 그 용도
|
MX2019008029A
(es)
|
2017-01-06 |
2019-12-11 |
Abl Bio Inc |
Anticuerpo anti-alfa-sinucleina y su uso.
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
KR20190117579A
(ko)
|
2017-02-16 |
2019-10-16 |
엑스바이오테크, 인크. |
화농성 한선염의 치료
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
CN110831969B
(zh)
|
2017-06-20 |
2024-06-21 |
安进公司 |
使用抑胃肽受体(gipr)结合蛋白与glp-1激动剂的组合治疗或改善代谢障碍的方法
|
JP7504025B2
(ja)
|
2017-08-04 |
2024-06-21 |
アムジエン・インコーポレーテツド |
Cys-mabのコンジュゲーション方法
|
WO2019117684A1
(ko)
|
2017-12-14 |
2019-06-20 |
에이비엘바이오 주식회사 |
a-syn/IGF1R에 대한 이중 특이 항체 및 그 용도
|
CA3087951A1
(en)
|
2018-01-12 |
2019-07-18 |
Amgen Inc. |
Pac1 antibodies and uses thereof
|
CA3099163A1
(en)
|
2018-05-01 |
2019-11-07 |
Amgen Inc. |
Antibodies with modulated glycan profiles
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
EP3836954A1
(de)
|
2018-08-13 |
2021-06-23 |
Iltoo Pharma |
Kombination von interleukin-2 mit einem interleukin-1-inhibitor, konjugate und therapeutische verwendungen davon
|
EP3894549B1
(de)
|
2018-12-10 |
2024-07-31 |
Amgen Inc. |
Mutierte piggybac-transposase
|
CN114174344A
(zh)
|
2019-05-30 |
2022-03-11 |
美国安进公司 |
工程改造铰链区以驱动抗体二聚化
|
MX2021015791A
(es)
|
2019-06-28 |
2022-04-01 |
Amgen Inc |
Proteínas de unión al antígeno biespecificas anti-receptor de cgrp/anti-receptor pac1.
|
CR20220111A
(es)
|
2019-08-13 |
2022-05-04 |
Amgen Inc |
Muteínas de interleucina-2 para la expansión de células t reguladoras referencia cruzada a solicitudes relacionadas
|
US20220389099A1
(en)
|
2019-11-04 |
2022-12-08 |
Amgen Inc. |
Methods for treating leukemia
|
US20220389119A1
(en)
|
2019-11-08 |
2022-12-08 |
Amgen Inc. |
ENGINEERING CHARGE PAIR MUTATIONS FOR PAIRING OF HETERO-IgG MOLECULES
|
JP2023501717A
(ja)
|
2019-11-19 |
2023-01-18 |
アムジエン・インコーポレーテツド |
新規の多重特異性抗体フォーマット
|
BR112022011949A2
(pt)
|
2019-12-17 |
2022-11-22 |
Amgen Inc |
Dupla de interleucina-2/agonista do receptor tnf para uso em terapia
|
CA3164129A1
(en)
|
2019-12-20 |
2021-06-24 |
Amgen Inc. |
Mesothelin-targeted cd40 agonistic multispecific antibody constructs for the treatment of solid tumors
|
WO2022040466A1
(en)
|
2020-08-20 |
2022-02-24 |
Amgen Inc. |
Antigen binding proteins with non-canonical disulfide in fab region
|
AU2021358033A1
(en)
|
2020-10-07 |
2023-05-04 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
TW202233660A
(zh)
|
2020-10-30 |
2022-09-01 |
美商安進公司 |
過表現胰島素樣生長因子受體突變體以調節igf補充
|
MX2023005379A
(es)
|
2020-11-10 |
2023-05-23 |
Amgen Inc |
Enlazadores novedosos de dominios de union a antigenos multiespecificos.
|
WO2022225921A1
(en)
|
2021-04-20 |
2022-10-27 |
Amgen Inc. |
Balanced charge distribution in electrostatic steering of chain pairing in multi-specific and monovalent igg molecule assembly
|
WO2022232376A1
(en)
|
2021-04-29 |
2022-11-03 |
Amgen Inc. |
Methods for reducing low molecular weight species of recombinantly-produced proteins
|
UY39807A
(es)
|
2021-06-10 |
2022-12-30 |
Amgen Inc |
VARIANTES GENOMODIFICADAS DE LA NRG-1 CON UNA SELECTIVIDAD MEJORADA FRENTE AL ErbB4 PERO NO FRENTE A
|
TW202328442A
(zh)
|
2021-09-10 |
2023-07-16 |
美商安進公司 |
平臺宿主對igf—培養基之適應
|
KR20240128067A
(ko)
|
2021-12-29 |
2024-08-23 |
브리스톨-마이어스 스큅 컴퍼니 |
랜딩 패드 세포주의 생성
|
WO2023172965A1
(en)
|
2022-03-09 |
2023-09-14 |
Amgen Inc. |
Optimized transfection protocol
|
EP4406973A1
(de)
|
2023-01-27 |
2024-07-31 |
Fundació Privada Institut de Recerca de la SIDA-Caixa |
Antikörper und verwendungen davon zur behandlung von infektionen durch eingehüllte viren
|