ATE158659T1 - Confokales abtast-endoskop - Google Patents

Confokales abtast-endoskop

Info

Publication number
ATE158659T1
ATE158659T1 AT89908146T AT89908146T ATE158659T1 AT E158659 T1 ATE158659 T1 AT E158659T1 AT 89908146 T AT89908146 T AT 89908146T AT 89908146 T AT89908146 T AT 89908146T AT E158659 T1 ATE158659 T1 AT E158659T1
Authority
AT
Austria
Prior art keywords
light
condenser
detector
field
scanning
Prior art date
Application number
AT89908146T
Other languages
English (en)
Inventor
Martin Russell Harris
Original Assignee
Optiscan Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25643506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE158659(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Optiscan Pty Ltd filed Critical Optiscan Pty Ltd
Application granted granted Critical
Publication of ATE158659T1 publication Critical patent/ATE158659T1/de

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/082—Condensers for incident illumination only
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/18—Arrangements with more than one light path, e.g. for comparing two specimens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microscoopes, Condenser (AREA)
  • Endoscopes (AREA)
  • Length Measuring Devices By Optical Means (AREA)
AT89908146T 1988-07-13 1989-07-13 Confokales abtast-endoskop ATE158659T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPI927088 1988-07-13
AUPI961888 1988-08-02

Publications (1)

Publication Number Publication Date
ATE158659T1 true ATE158659T1 (de) 1997-10-15

Family

ID=25643506

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89908146T ATE158659T1 (de) 1988-07-13 1989-07-13 Confokales abtast-endoskop

Country Status (5)

Country Link
US (1) US5120953A (de)
EP (3) EP1245987B1 (de)
AT (1) ATE158659T1 (de)
DE (4) DE02012428T1 (de)
WO (1) WO1990000754A1 (de)

Families Citing this family (225)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1325537C (en) * 1988-08-01 1993-12-28 Timothy Peter Dabbs Confocal microscope
EP0666487A2 (de) * 1989-09-22 1995-08-09 Fuji Photo Film Co., Ltd. Rastermikroskop und Abtastmechanismus für dasselbe
JP3052150B2 (ja) * 1990-04-06 2000-06-12 オプティスキャン・ピーティワイ・リミテッド 共焦点顕微鏡
DE69121633T2 (de) * 1990-05-22 1997-01-16 Tsutomu Ichimura Verfahren und Apparat zur Messung spektraler Absorption in undurchsichtigem Material und Verfahren und Apparat zur Messung einer Verteilung mikroskopischer Absorption
US5127730A (en) * 1990-08-10 1992-07-07 Regents Of The University Of Minnesota Multi-color laser scanning confocal imaging system
AU8765891A (en) * 1990-10-02 1992-04-28 Patrick Foulgoc Camera and projection device
DE69227902T3 (de) 1991-04-29 2010-04-22 Massachusetts Institute Of Technology, Cambridge Vorrichtung für optische abbildung und messung
DE9110926U1 (de) * 1991-09-03 1991-12-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften eV, 37073 Göttingen Blitzlicht-Beleuchtungseinrichtung für ein Mikroskop
JP3082346B2 (ja) * 1991-09-12 2000-08-28 株式会社ニコン 蛍光コンフォーカル顕微鏡
US5347656A (en) * 1992-07-10 1994-09-20 Ccc Acquisitions Corp. Figure-enhancing pneumatic bathing suit
AU669760B2 (en) * 1992-10-23 1996-06-20 Monash University Confocal microscope and endoscope
US5659642A (en) * 1992-10-23 1997-08-19 Optiscan Pty. Ltd. Confocal microscope and endoscope
US5450203A (en) * 1993-12-22 1995-09-12 Electroglas, Inc. Method and apparatus for determining an objects position, topography and for imaging
US20050111089A1 (en) * 1994-07-15 2005-05-26 Baer Stephen C. Superresolving microscopy apparatus
US5880880A (en) * 1995-01-13 1999-03-09 The General Hospital Corp. Three-dimensional scanning confocal laser microscope
WO1996021938A1 (en) * 1995-01-13 1996-07-18 The General Hospital Corporation Video-rate confocal scanning laser microscope
CA2215975A1 (en) * 1995-03-24 1996-10-03 Optiscan Pty. Ltd. Optical fibre confocal imager with variable near-confocal control
US6175754B1 (en) 1995-06-07 2001-01-16 Keravision, Inc. Method and apparatus for measuring corneal incisions
US5785651A (en) * 1995-06-07 1998-07-28 Keravision, Inc. Distance measuring confocal microscope
US6263233B1 (en) 1995-07-13 2001-07-17 Lucid, Inc. Handheld imaging microscope
US5788639A (en) * 1995-07-13 1998-08-04 Lucid Technologies, Inc. Confocal imaging through thick dermal tissue
US7047064B1 (en) * 1995-07-13 2006-05-16 Lucid, Inc. Microscopic imaging apparatus and method
US6104945A (en) * 1995-08-01 2000-08-15 Medispectra, Inc. Spectral volume microprobe arrays
US5713364A (en) * 1995-08-01 1998-02-03 Medispectra, Inc. Spectral volume microprobe analysis of materials
US5813987A (en) * 1995-08-01 1998-09-29 Medispectra, Inc. Spectral volume microprobe for analysis of materials
US5874726A (en) * 1995-10-10 1999-02-23 Iowa State University Research Foundation Probe-type near-field confocal having feedback for adjusting probe distance
US5907425A (en) * 1995-12-19 1999-05-25 The Board Of Trustees Of The Leland Stanford Junior University Miniature scanning confocal microscope
US6749346B1 (en) 1995-11-07 2004-06-15 The Board Of Trustees Of The Leland Stanford Junior University Miniature scanning confocal microscope
US6081499A (en) * 1997-05-05 2000-06-27 Seagate Technology, Inc. Magneto-optical data storage system having an optical-processing flying head
DE19640496A1 (de) * 1996-10-01 1998-04-02 Leica Lasertechnik Verfahren zur Oberflächenvermessung mittels Konfokalmikroskopie
US6424852B1 (en) * 1996-10-18 2002-07-23 Lucid, Inc. System for confocal imaging within dermal tissue
US6745067B1 (en) * 1998-09-14 2004-06-01 Lucid, Inc. System for marking the locations of imaged tissue with respect to the surface of the tissue
US6826422B1 (en) * 1997-01-13 2004-11-30 Medispectra, Inc. Spectral volume microprobe arrays
US6847490B1 (en) 1997-01-13 2005-01-25 Medispectra, Inc. Optical probe accessory device for use in vivo diagnostic procedures
DE19758744C2 (de) * 1997-01-27 2003-08-07 Zeiss Carl Jena Gmbh Laser-Scanning-Mikroskop
US5887009A (en) * 1997-05-22 1999-03-23 Optical Biopsy Technologies, Inc. Confocal optical scanning system employing a fiber laser
US5876946A (en) * 1997-06-03 1999-03-02 Pharmacopeia, Inc. High-throughput assay
EP1925961B1 (de) 1997-06-30 2017-03-29 Lucid, Inc. Konfokale Abbildung durch dickes Hautgewebe
US6967772B2 (en) * 1997-07-16 2005-11-22 Optiscan Pty Ltd Scanning microscope with miniature head
US6327493B1 (en) 1997-08-28 2001-12-04 Olympus Optical Co., Ltd. Light scanning devices of a water-tight structure to be inserted into a body cavity to obtain optical information on inside of a biological tissue
US6069698A (en) * 1997-08-28 2000-05-30 Olympus Optical Co., Ltd. Optical imaging apparatus which radiates a low coherence light beam onto a test object, receives optical information from light scattered by the object, and constructs therefrom a cross-sectional image of the object
US6121603A (en) * 1997-12-01 2000-09-19 Hang; Zhijiang Optical confocal device having a common light directing means
WO1999043994A1 (en) 1998-02-26 1999-09-02 Lucid, Inc. Confocal microscope for facilitating cryosurgery of tissue
US6370422B1 (en) * 1998-03-19 2002-04-09 Board Of Regents, The University Of Texas System Fiber-optic confocal imaging apparatus and methods of use
US6298027B1 (en) 1998-03-30 2001-10-02 Seagate Technology Llc Low-birefringence optical fiber for use in an optical data storage system
JP3833895B2 (ja) 1998-03-30 2006-10-18 シーゲイト テクノロジー エルエルシー スプリアス反射からの雑音を低減する手段を備えた光データ記憶システム
US6574015B1 (en) 1998-05-19 2003-06-03 Seagate Technology Llc Optical depolarizer
DE19829981C2 (de) 1998-07-04 2002-10-17 Zeiss Carl Jena Gmbh Verfahren und Anordnung zur konfokalen Mikroskopie
AUPP548298A0 (en) * 1998-08-27 1998-09-17 Optiscan Pty Limited Compact confocal endoscope and endomicroscope method and apparatus
FR2783330B1 (fr) * 1998-09-15 2002-06-14 Assist Publ Hopitaux De Paris Dispositif d'observation de l'interieur d'un corps produisant une qualite d'observation perfectionnee
US6426490B1 (en) * 1998-11-16 2002-07-30 Leica Microsystems Heidelberg Gmbh Method for operating a preferably confocal laser scanning microscope
AU760402B2 (en) 1998-12-23 2003-05-15 Medispectra, Inc. Optical methods and systems for cervical screening
CA2356623C (en) 1998-12-23 2005-10-18 Medispectra, Inc. Systems and methods for optical examination of samples
AU3493800A (en) 1999-02-17 2000-09-04 Lucid, Inc. Cassette for facilitating optical sectioning of a retained tissue specimen
AU2882800A (en) * 1999-02-17 2000-09-04 Lucid, Inc. Tissue specimen holder
JP2000258699A (ja) 1999-03-05 2000-09-22 Olympus Optical Co Ltd 直視型共焦点光学系
US6181474B1 (en) 1999-03-22 2001-01-30 Kovex Corporation Scanning confocal microscope with objective lens position tracking
US6548796B1 (en) * 1999-06-23 2003-04-15 Regents Of The University Of Minnesota Confocal macroscope
GB9922468D0 (en) * 1999-09-22 1999-11-24 B J R Systems Ltd Confocal imaging apparatus for turbid viewing
JP2001174744A (ja) 1999-10-06 2001-06-29 Olympus Optical Co Ltd 光走査プローブ装置
US6320174B1 (en) * 1999-11-16 2001-11-20 Ikonisys Inc. Composing microscope
US6545260B1 (en) 1999-11-19 2003-04-08 Olympus Optical Co., Ltd. Light scanning optical device which acquires a high resolution two-dimensional image without employing a charge-coupled device
US7260248B2 (en) 1999-12-15 2007-08-21 Medispectra, Inc. Image processing using measures of similarity
US7187810B2 (en) 1999-12-15 2007-03-06 Medispectra, Inc. Methods and systems for correcting image misalignment
US6902935B2 (en) * 1999-12-15 2005-06-07 Medispectra, Inc. Methods of monitoring effects of chemical agents on a sample
US6567585B2 (en) 2000-04-04 2003-05-20 Optiscan Pty Ltd Z sharpening for fibre confocal microscopes
JP2001311880A (ja) 2000-04-28 2001-11-09 Olympus Optical Co Ltd 小型共焦点光学系
US6747795B2 (en) * 2000-06-30 2004-06-08 The General Hospital Corporation Fiber-coupled multiplexed confocal microscope
US6530882B1 (en) * 2000-06-30 2003-03-11 Inner Vision Imaging, L.L.C. Endoscope having microscopic and macroscopic magnification
JP4668392B2 (ja) 2000-07-26 2011-04-13 オリンパス株式会社 光走査光学系および内視鏡
US6351325B1 (en) 2000-07-28 2002-02-26 Optical Biopsy Technologies, Inc. Fiber-coupled, angled-dual-axis confocal scanning microscopes for imaging in a scattering medium
US6441356B1 (en) * 2000-07-28 2002-08-27 Optical Biopsy Technologies Fiber-coupled, high-speed, angled-dual-axis optical coherence scanning microscopes
US6423956B1 (en) 2000-07-28 2002-07-23 Optical Biopsy Technologies Fiber-coupled, high-speed, integrated, angled-dual-axis confocal scanning microscopes employing vertical cross-section scanning
US7560697B2 (en) * 2000-08-29 2009-07-14 Perkinelmer Singapore Pte. Ltd. Detector array and cross-talk linearity connection
DE60044580D1 (de) * 2000-08-29 2010-08-05 Perkinelmer Singapore Pte Ltd Mikroskop für Infrarotabbildung
JP4241038B2 (ja) 2000-10-30 2009-03-18 ザ ジェネラル ホスピタル コーポレーション 組織分析のための光学的な方法及びシステム
US6369928B1 (en) 2000-11-01 2002-04-09 Optical Biopsy Technologies, Inc. Fiber-coupled, angled-dual-illumination-axis confocal scanning microscopes for performing reflective and two-photon fluorescence imaging
US7194118B1 (en) 2000-11-10 2007-03-20 Lucid, Inc. System for optically sectioning and mapping surgically excised tissue
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
EP1343973B2 (de) 2000-11-16 2020-09-16 California Institute Of Technology Vorrichtung und verfahren zur durchführung von assays und screening mit hohem durchsatz
US6414779B1 (en) 2000-11-30 2002-07-02 Opeical Biopsy Technologies, Inc. Integrated angled-dual-axis confocal scanning endoscopes
US6839661B2 (en) 2000-12-15 2005-01-04 Medispectra, Inc. System for normalizing spectra
US7120501B2 (en) * 2001-01-23 2006-10-10 Microphonics, Inc. Transcanal cochlear implant system
DE10121064A1 (de) 2001-04-28 2002-10-31 Evotec Ag Vorrichtung und Verfahren zur optischen Messung von chemischen und/oder biologischen Proben
US9897538B2 (en) * 2001-04-30 2018-02-20 The General Hospital Corporation Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating
DE10297689B4 (de) * 2001-05-01 2007-10-18 The General Hospital Corp., Boston Verfahren und Gerät zur Bestimmung von atherosklerotischem Belag durch Messung von optischen Gewebeeigenschaften
US7616986B2 (en) * 2001-05-07 2009-11-10 University Of Washington Optical fiber scanner for performing multimodal optical imaging
DE10125885B4 (de) 2001-05-28 2004-09-16 Siemens Ag Sensorvorrichtung zur schnellen optischen Abstandsmessung nach dem konfokalen optischen Abbildungsprinzip
US6809866B2 (en) * 2001-08-03 2004-10-26 Olympus Corporation Optical imaging apparatus
US6980299B1 (en) * 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
JP3678192B2 (ja) * 2001-11-21 2005-08-03 横河電機株式会社 計測装置
US8423110B2 (en) * 2002-01-09 2013-04-16 Boston Scientific Scimed, Inc. Imaging device and related methods
AU2003207507A1 (en) * 2002-01-11 2003-07-30 Gen Hospital Corp Apparatus for oct imaging with axial line focus for improved resolution and depth of field
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US8620410B2 (en) * 2002-03-12 2013-12-31 Beth Israel Deaconess Medical Center Multi-channel medical imaging system
EP1485011B1 (de) * 2002-03-12 2013-02-13 Beth Israel Deaconess Medical Center Medizinische bildgebungssysteme
US7459696B2 (en) 2003-04-18 2008-12-02 Schomacker Kevin T Methods and apparatus for calibrating spectral data
US7469160B2 (en) 2003-04-18 2008-12-23 Banks Perry S Methods and apparatus for evaluating image focus
US6933154B2 (en) * 2002-07-09 2005-08-23 Medispectra, Inc. Optimal windows for obtaining optical data for characterization of tissue samples
US7136518B2 (en) 2003-04-18 2006-11-14 Medispectra, Inc. Methods and apparatus for displaying diagnostic data
US20040208385A1 (en) * 2003-04-18 2004-10-21 Medispectra, Inc. Methods and apparatus for visually enhancing images
US7309867B2 (en) 2003-04-18 2007-12-18 Medispectra, Inc. Methods and apparatus for characterization of tissue samples
US7282723B2 (en) 2002-07-09 2007-10-16 Medispectra, Inc. Methods and apparatus for processing spectral data for use in tissue characterization
US6818903B2 (en) * 2002-07-09 2004-11-16 Medispectra, Inc. Method and apparatus for identifying spectral artifacts
US6768918B2 (en) 2002-07-10 2004-07-27 Medispectra, Inc. Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof
US7103401B2 (en) 2002-07-10 2006-09-05 Medispectra, Inc. Colonic polyp discrimination by tissue fluorescence and fiberoptic probe
US7252634B2 (en) * 2002-11-05 2007-08-07 Pentax Corporation Confocal probe having scanning mirrors mounted to a transparent substrate in an optical path of the probe
JP2004222870A (ja) * 2003-01-21 2004-08-12 Pentax Corp 内視鏡用プローブ
AU2004206998B2 (en) * 2003-01-24 2009-12-17 The General Hospital Corporation System and method for identifying tissue using low-coherence interferometry
US8054468B2 (en) 2003-01-24 2011-11-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
JP4320184B2 (ja) * 2003-02-10 2009-08-26 Ｈｏｙａ株式会社 対物レンズユニット、該対物レンズユニットの組立方法
DE102004006541B4 (de) 2003-02-10 2016-11-10 Hoya Corp. Endoskop
US7154083B2 (en) * 2003-02-24 2006-12-26 Pentax Corporation Confocal probe
AU2004225188B2 (en) 2003-03-31 2010-04-15 The General Hospital Corporation Speckle reduction in optical coherence tomography by path length encoded angular compounding
JP4603816B2 (ja) * 2003-05-16 2010-12-22 オプティスキャン ピーティーワイ リミテッド 光コネクタ
US7519096B2 (en) 2003-06-06 2009-04-14 The General Hospital Corporation Process and apparatus for a wavelength tuning source
KR100556232B1 (ko) * 2003-07-23 2006-03-03 국립암센터 이격조절이 가능한 양안구조 복강경
DE10335466B4 (de) 2003-08-02 2005-09-01 Leica Microsystems Heidelberg Gmbh Rastermikroskop
US8473035B2 (en) * 2003-09-15 2013-06-25 Beth Israel Deaconess Medical Center Medical imaging systems
DE602004014697D1 (de) * 2003-10-17 2008-08-14 Olympus Co Objektiveinführvorrichtung, Befestigungsvorrichtung für ein Objektivsystem
CN103181753B (zh) 2003-10-27 2016-12-28 通用医疗公司 用于使用频域干涉测量法进行光学成像的方法和设备
EP1687587B1 (de) * 2003-11-28 2020-01-08 The General Hospital Corporation Verfahren und vorrichtung für dreidimensionale spektralcodierte bildgebung
JP2005189475A (ja) * 2003-12-25 2005-07-14 Fujinon Corp 顕微鏡装置
EP1566617B1 (de) * 2004-02-20 2015-11-11 Carestream Health, Inc. Vorrichtung und Verfahren zur Zahnfarbenbestimmung
US7233437B2 (en) 2004-03-25 2007-06-19 Olympus Corporation Laser-scanning microscope
JP4694139B2 (ja) * 2004-04-01 2011-06-08 オリンパス株式会社 顕微鏡
EP1754016B1 (de) 2004-05-29 2016-05-18 The General Hospital Corporation Prozess, system und softwareanordnung für eine kompensation der chromatischen dispersion unter verwendung reflektierender schichten in der bildgebenden optischen kohärenztopographie (oct)
JP4995720B2 (ja) 2004-07-02 2012-08-08 ザ ジェネラル ホスピタル コーポレイション ダブルクラッドファイバを有する内視鏡撮像プローブ
WO2006017837A2 (en) 2004-08-06 2006-02-16 The General Hospital Corporation Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
KR20120062944A (ko) 2004-08-24 2012-06-14 더 제너럴 하스피탈 코포레이션 혈관절편 영상화 방법 및 장치
EP1989997A1 (de) 2004-08-24 2008-11-12 The General Hospital Corporation Verfahren, Vorrichtung und Software-Anordnung zur Messung einer mechanischen Belastung und elastischer Eigenschaften einer Probe
JP5215664B2 (ja) 2004-09-10 2013-06-19 ザ ジェネラル ホスピタル コーポレイション 光学コヒーレンス撮像のシステムおよび方法
EP2329759B1 (de) 2004-09-29 2014-03-12 The General Hospital Corporation System und Verfahren zur Abbildung optischer Kohärenz
EP1650529A1 (de) * 2004-10-19 2006-04-26 Diener AG Precision Machining Anordnung und Verfahren zum Abtasten mehrerer Objekte
EP1819270B1 (de) * 2004-10-29 2012-12-19 The General Hospital Corporation Polarisationsempfindliche optische kohärenztomographie
US7382949B2 (en) * 2004-11-02 2008-06-03 The General Hospital Corporation Fiber-optic rotational device, optical system and method for imaging a sample
EP1825214A1 (de) 2004-11-24 2007-08-29 The General Hospital Corporation Interferometer mit gemeinsamem pfad für endoskopische optische kohärenztomographie
JP2008521453A (ja) * 2004-11-25 2008-06-26 オプティスカン・ピーティーワイ・リミテッド エンドスコープ
WO2006058346A1 (en) 2004-11-29 2006-06-01 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
JP4759277B2 (ja) * 2005-01-21 2011-08-31 オリンパス株式会社 観察方法および観察補助具
US8456738B2 (en) * 2005-04-14 2013-06-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ultrahigh-resolution fiber-optic confocal microscope and method
EP1875436B1 (de) 2005-04-28 2009-12-09 The General Hospital Corporation Bewertung von bildmerkmalen einer anatomischen struktur in optischen kohärenztomographiebildern
US9055867B2 (en) 2005-05-12 2015-06-16 Caliber Imaging & Diagnostics, Inc. Confocal scanning microscope having optical and scanning systems which provide a handheld imaging head
EP1887926B1 (de) * 2005-05-31 2014-07-30 The General Hospital Corporation System und verfahren die spektrale interferometrietechniken zur codierungsüberlagerung zur bildgebung benutzen
US9060689B2 (en) 2005-06-01 2015-06-23 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
ES2354287T3 (es) 2005-08-09 2011-03-11 The General Hospital Corporation Aparato y método para realizar una desmodulación en cuadratura por polarización en tomografía de coherencia óptica.
GB0519761D0 (en) * 2005-09-28 2005-11-09 Point Source Ltd Laser systems
US7843572B2 (en) * 2005-09-29 2010-11-30 The General Hospital Corporation Method and apparatus for optical imaging via spectral encoding
WO2007047690A1 (en) 2005-10-14 2007-04-26 The General Hospital Corporation Spectral- and frequency- encoded fluorescence imaging
CA2632557C (en) * 2005-12-08 2016-06-14 Peter S. Lovely Infrared dental imaging
JP5680826B2 (ja) 2006-01-10 2015-03-04 ザ ジェネラル ホスピタル コーポレイション １以上のスペクトルを符号化する内視鏡技術によるデータ生成システム
WO2007084945A1 (en) * 2006-01-19 2007-07-26 The General Hospital Corporation Systems and methods for performing rapid fluorescense lifetime, excitation and emission spectral measurements
EP1973466B1 (de) 2006-01-19 2021-01-06 The General Hospital Corporation Ballonbildgebungskatheter
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
WO2007084959A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel microscopy
JP5680829B2 (ja) 2006-02-01 2015-03-04 ザ ジェネラル ホスピタル コーポレイション 複数の電磁放射をサンプルに照射する装置
JP5524487B2 (ja) 2006-02-01 2014-06-18 ザ ジェネラル ホスピタル コーポレイション コンフォーマルレーザ治療手順を用いてサンプルの少なくとも一部分に電磁放射を放射する方法及びシステム。
JP2009537024A (ja) * 2006-02-01 2009-10-22 ザ ジェネラル ホスピタル コーポレイション 少なくとも一つのファイバの少なくとも二つの部位の少なくとも一つを制御する装置
EP3143926B1 (de) 2006-02-08 2020-07-01 The General Hospital Corporation Verfahren, anordnungen und systeme zum abrufen von informationen im zusammenhang mit einer anatomischen probe mithilfe eines optischen mikroskops
JP2009527770A (ja) 2006-02-24 2009-07-30 ザ ジェネラル ホスピタル コーポレイション 角度分解型のフーリエドメイン光干渉断層撮影法を遂行する方法及びシステム
US20070239033A1 (en) * 2006-03-17 2007-10-11 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
WO2007118129A1 (en) * 2006-04-05 2007-10-18 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
WO2007133961A2 (en) 2006-05-10 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
US7782464B2 (en) * 2006-05-12 2010-08-24 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
EP3006920A3 (de) 2006-08-25 2016-08-03 The General Hospital Corporation Vorrichtungen und verfahren zur verstärkung von optischer kohärenztomografiebildgebung mithilfe volumetrischer filterungsverfahren
US8838213B2 (en) 2006-10-19 2014-09-16 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s)
GB0621585D0 (en) 2006-10-30 2006-12-06 Secretary Trade Ind Brit Confocal microscope
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
EP2662674A3 (de) 2007-01-19 2014-06-25 The General Hospital Corporation Drehscheibenreflexion zur schnellen Wellenlängendurchstimmung von dispergiertem Breitbandlicht
JP5507258B2 (ja) 2007-01-19 2014-05-28 ザ ジェネラル ホスピタル コーポレイション 光周波数領域イメージングにおける測定深度を制御するための装置及び方法
US20080234586A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome using exemplary laser speckle imaging procedure
JP5558839B2 (ja) 2007-03-23 2014-07-23 ザ ジェネラル ホスピタル コーポレイション 角度走査及び分散手順を用いて波長掃引レーザを利用するための方法、構成及び装置
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US8045177B2 (en) 2007-04-17 2011-10-25 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy
US8115919B2 (en) 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
WO2009013663A2 (en) 2007-07-20 2009-01-29 Koninklijke Philips Electronics N.V. Fiber-optic scanner
US9375158B2 (en) 2007-07-31 2016-06-28 The General Hospital Corporation Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging
US8040608B2 (en) 2007-08-31 2011-10-18 The General Hospital Corporation System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith
EP2207469A4 (de) * 2007-10-12 2012-07-11 Gen Hospital Corp Systeme und verfahren zur optischen bildgebung von luminalen anatomischen strukturen
WO2009059034A1 (en) 2007-10-30 2009-05-07 The General Hospital Corporation System and method for cladding mode detection
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
JP5607610B2 (ja) 2008-05-07 2014-10-15 ザ ジェネラル ホスピタル コーポレイション 構造の特徴を決定する装置、装置の作動方法およびコンピュータアクセス可能な媒体
US8861910B2 (en) 2008-06-20 2014-10-14 The General Hospital Corporation Fused fiber optic coupler arrangement and method for use thereof
WO2010009136A2 (en) 2008-07-14 2010-01-21 The General Hospital Corporation Apparatus and methods for color endoscopy
US8937724B2 (en) 2008-12-10 2015-01-20 The General Hospital Corporation Systems and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
JP2012515930A (ja) 2009-01-26 2012-07-12 ザ ジェネラル ホスピタル コーポレーション 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体
CN102308444B (zh) * 2009-02-04 2014-06-18 通用医疗公司 利用高速光学波长调谐源的设备和方法
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
BR112012001042A2 (pt) 2009-07-14 2016-11-22 Gen Hospital Corp equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica.
FR2950441B1 (fr) * 2009-09-23 2012-05-18 Sabban Youssef Cohen Capteur optique dote de champ lateral pour la numerisation 3d
RS61066B1 (sr) 2010-03-05 2020-12-31 Massachusetts Gen Hospital Sistemi koji obezbeđuju mikroskopske slike najmanje jedne anatomske strukture na određenoj rezoluciji
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
EP2575597B1 (de) 2010-05-25 2022-05-04 The General Hospital Corporation Vorrichtung zur bereitstellung einer optischen bildgebung für strukturen und zusammensetzungen
US9795301B2 (en) 2010-05-25 2017-10-24 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
US10285568B2 (en) 2010-06-03 2019-05-14 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
EP2632324A4 (de) 2010-10-27 2015-04-22 Gen Hospital Corp Vorrichtungen, systeme und verfahren zur blutdruckmessung in mindestens einem gefäss
JP6240064B2 (ja) 2011-04-29 2017-11-29 ザ ジェネラル ホスピタル コーポレイション 散乱媒質の深さ分解した物理的及び／又は光学的特性を決定する方法
KR101838329B1 (ko) 2011-05-20 2018-03-13 유니베르시타트 폴리테크니카 데 카탈루냐 표면을 비접촉 측정하기 위한 방법 및 디바이스
US9330092B2 (en) 2011-07-19 2016-05-03 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
WO2013029047A1 (en) 2011-08-25 2013-02-28 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
EP2769491A4 (de) 2011-10-18 2015-07-22 Gen Hospital Corp Vorrichtung und verfahren zur herstellung und/oder bereitstellung rezirkulierender optischer verzögerung(en)
DE102011116403B4 (de) * 2011-10-19 2013-05-29 Rodenstock Gmbh Vorrichtung und Verfahren zur Messung von Oberflächen oder Grenzflächen
JP6170498B2 (ja) * 2011-11-14 2017-07-26 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 関連する物体の走査顕微鏡撮像のための光学顕微鏡プローブ
JP5930364B2 (ja) * 2011-11-28 2016-06-08 国立大学法人京都大学 生体試料固定器
US9229210B2 (en) 2012-02-26 2016-01-05 Caliber Imaging And Diagnostics, Inc. Tissue specimen stage for an optical sectioning microscope
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
WO2013177154A1 (en) 2012-05-21 2013-11-28 The General Hospital Corporation Apparatus, device and method for capsule microscopy
EP2888616A4 (de) 2012-08-22 2016-04-27 Gen Hospital Corp System, verfahren, und über computer zugängliches medium zur herstellung eines miniaturendoskops mit weicher lithografie
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
US11179028B2 (en) 2013-02-01 2021-11-23 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
JP6378311B2 (ja) 2013-03-15 2018-08-22 ザ ジェネラル ホスピタル コーポレイション 物体を特徴付ける方法とシステム
EP2997354A4 (de) 2013-05-13 2017-01-18 The General Hospital Corporation Erkennung einer selbstinterferierenden fluoreszenzphase und amplitude
US10117576B2 (en) 2013-07-19 2018-11-06 The General Hospital Corporation System, method and computer accessible medium for determining eye motion by imaging retina and providing feedback for acquisition of signals from the retina
US10045696B2 (en) * 2013-07-19 2018-08-14 Wisconsin Alumni Research Foundation Tissue fluorescence monitor with ambient light rejection
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
EP3910282B1 (de) 2013-07-26 2024-01-17 The General Hospital Corporation Verfahren zur erzeugung von laserstrahlung mit einer optische dispersion nutzenden laseranordnung für anwendungen in der fourier-raum optischen kohärenztomographie
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
KR102513779B1 (ko) 2014-07-25 2023-03-24 더 제너럴 하스피탈 코포레이션 생체 내 이미징 및 진단을 위한 장치, 디바이스 및 방법
US20170307437A1 (en) * 2014-10-01 2017-10-26 Phonoptics Opto-mechanical transducer for the detection of vibrations
FR3030956B1 (fr) * 2014-12-18 2018-03-23 Centre National De La Recherche Scientifique - Cnrs Dispositif de transport et de controle d'impulsions lumineuses pour l'imagerie endo-microscopique sans lentille
DE102015202605B4 (de) * 2015-02-12 2017-03-09 Carl Zeiss Meditec Ag Visualisierungssystem
JP2017075947A (ja) 2015-10-14 2017-04-20 アッベリオー インストラメンツ ゲーエムベーハーＡｂｂｅｒｉｏｒ Ｉｎｓｔｒｕｍｅｎｔｓ ＧｍｂＨ スキャナヘッド及びスキャナヘッド付き装置

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH600301A5 (de) * 1976-05-28 1978-06-15 Bbc Brown Boveri & Cie
GB2038017B (en) * 1978-12-20 1982-11-24 Standard Telephones Cables Ltd Optical fibre directional coupler
DE2936463A1 (de) 1979-09-10 1981-03-19 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zum erzeugen bewegter lichtstrahlengaenge
AU7072981A (en) * 1980-08-27 1982-03-17 Urban, P. Endoscopic system
US4500204A (en) * 1981-04-21 1985-02-19 Agency Of Industrial Science & Technology Scanning-type lithographic and image-pickup device using optical fiber
US4634880A (en) * 1982-04-19 1987-01-06 Siscan Systems, Inc. Confocal optical imaging system with improved signal-to-noise ratio
US4626679A (en) * 1982-09-22 1986-12-02 Canon Kabushiki Kaisha Optical head and method of detecting the focus thereof
US4481418A (en) * 1982-09-30 1984-11-06 Vanzetti Systems, Inc. Fiber optic scanning system for laser/thermal inspection
EP0112401B1 (de) * 1982-12-27 1987-04-22 International Business Machines Corporation Optisches Nahfeldabtastmikroskop
JPS59223677A (ja) 1983-06-01 1984-12-15 三菱電機株式会社 エレベ−タかご室の表示装置
US4589404A (en) * 1984-01-03 1986-05-20 Medical Dynamics, Inc. Laser endoscope
US4754328A (en) * 1984-01-03 1988-06-28 Medical Dynamics, Inc. Laser endoscope
EP0156181B1 (de) 1984-03-05 1989-05-24 Siemens Aktiengesellschaft Optisches System zum gleichzeitigen Empfang von Wärme- und Laserstrahlung
EP0185782B1 (de) * 1984-12-28 1989-03-15 International Business Machines Corporation Wellenleiter für ein optisches Nahfeldmikroskop
FR2575889B1 (fr) * 1985-01-09 1987-03-20 Electricite De France Microcamera de television
GB8524742D0 (en) * 1985-10-08 1985-11-13 Iravani M V Fibre optic scanning systems
JPS62211503A (ja) 1986-03-13 1987-09-17 Hitachi Ltd 段差計測装置
GB8617570D0 (en) * 1986-07-18 1986-08-28 See C W Microscopes
EP0283256A3 (de) * 1987-03-18 1990-02-07 Tektronix Inc. Optisches Abtastmikroskop
US4827125A (en) 1987-04-29 1989-05-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Confocal scanning laser microscope having no moving parts
US4768874A (en) 1987-09-10 1988-09-06 Eye Research Institute Of Retina Foundation Scanning optical apparatus and method
DE3853475T2 (de) * 1987-09-24 1995-09-14 Univ Washington Konzept und umwandlungssatz eines standardmikroskops in ein mikroskop mit gemeinsamem brennpunkt und epi-beleuchtung mit einzelöffnung.
US4959552A (en) * 1988-02-09 1990-09-25 Carl-Zeiss-Stiftung Microscope arranged for measuring microscopic structures
CA1325537C (en) * 1988-08-01 1993-12-28 Timothy Peter Dabbs Confocal microscope

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EP1245987B1 (de) 2008-01-23
DE68929464T2 (de) 2003-11-20
DE68928345D1 (de) 1997-10-30
EP1245987A2 (de) 2002-10-02
DE68928345T2 (de) 1998-05-07
DE02012428T1 (de) 2005-12-15
EP0393165A1 (de) 1990-10-24
DE68929553D1 (de) 2008-03-13
EP0782027A3 (de) 1997-07-30
DE68929553T2 (de) 2009-01-29
EP1245987A3 (de) 2004-08-25
EP0782027A2 (de) 1997-07-02
DE68928345T3 (de) 2008-03-06
EP0782027B1 (de) 2003-04-16
DE68929464D1 (de) 2003-05-22
US5120953A (en) 1992-06-09
WO1990000754A1 (en) 1990-01-25
EP0393165B2 (de) 2007-07-25
EP0393165B1 (de) 1997-09-24
EP0393165A4 (en) 1991-07-24

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