ATE155469T1 - Verfahren zur herstellung von cephemderivaten - Google Patents

Verfahren zur herstellung von cephemderivaten

Info

Publication number
ATE155469T1
ATE155469T1 AT89104575T AT89104575T ATE155469T1 AT E155469 T1 ATE155469 T1 AT E155469T1 AT 89104575 T AT89104575 T AT 89104575T AT 89104575 T AT89104575 T AT 89104575T AT E155469 T1 ATE155469 T1 AT E155469T1
Authority
AT
Austria
Prior art keywords
sub
compound
cephem derivatives
group
sup
Prior art date
Application number
AT89104575T
Other languages
English (en)
Inventor
Takashi Kamiya
Toshihiko Naito
Yuuki Komatu
Yasunobu Kai
Takaharu Nakamura
Masanobu Sasho
Shigeto Negi
Isao Sugiyama
Kanemasa Katsu
Hiroshi Yamauchi
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE155469T1 publication Critical patent/ATE155469T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT89104575T 1988-03-16 1989-03-15 Verfahren zur herstellung von cephemderivaten ATE155469T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6051188 1988-03-16

Publications (1)

Publication Number Publication Date
ATE155469T1 true ATE155469T1 (de) 1997-08-15

Family

ID=13144412

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96115297T ATE212027T1 (de) 1988-03-16 1989-03-15 Cephemderivate und verfahren zu ihrer herstellung
AT89104575T ATE155469T1 (de) 1988-03-16 1989-03-15 Verfahren zur herstellung von cephemderivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT96115297T ATE212027T1 (de) 1988-03-16 1989-03-15 Cephemderivate und verfahren zu ihrer herstellung

Country Status (12)

Country Link
US (1) US5128465A (de)
EP (3) EP0612751A3 (de)
JP (1) JPH07179472A (de)
CN (1) CN1022837C (de)
AT (2) ATE212027T1 (de)
CA (1) CA1339738C (de)
DE (2) DE68928174T2 (de)
ES (1) ES2013403A6 (de)
GR (1) GR1000462B (de)
HU (1) HU215925B (de)
PT (1) PT90022B (de)
YU (1) YU46998B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0421297B1 (de) * 1989-09-30 1993-12-01 Eisai Co., Ltd. Injizierbare Cephalosporinpräparate und ihre Anwendung
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
KR950014571B1 (ko) * 1991-11-18 1995-12-08 제일제당주식회사 세펨 유도체의 제조방법
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
FR2722790B1 (fr) 1994-07-19 1996-10-04 Roussel Uclaf Nouvelles cephalosporines comportant en position 7 un radical benzyloxymino subtitue, leur procede de preparation leur application comme medicaments
JPH08151354A (ja) 1994-11-29 1996-06-11 Eisai Kagaku Kk アミノアセトアミド誘導体の製造法
KR0174117B1 (ko) * 1995-12-28 1999-02-01 윤원영 새로운 세팔로스포린 유도체 및 그 제조방법
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
CA2216259A1 (en) * 1996-09-25 1998-03-25 Eisai Chemical Co., Ltd. Production process of cephem compound
AU761450B2 (en) * 1998-06-22 2003-06-05 Basilea Pharmaceutica Ag Propenyl cephalosporin derivatives
KR100441901B1 (ko) * 2001-07-02 2004-07-27 일동제약주식회사 세팔로스포린 유도체의 개선된 제조방법
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
MX338505B (es) 2005-12-07 2016-04-20 Basilea Pharmaceutica Ag Combinaciones utiles de antibioticos de monobactama con inhibidores de beta-lactamasa.
CN105418641B (zh) * 2015-12-30 2018-08-10 广东金城金素制药有限公司 一种原研制品质头孢曲松钠及其药物制剂
WO2018185211A1 (en) 2017-04-06 2018-10-11 Syngenta Participations Ag Microbiocidal oxadiazole derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB762850A (en) * 1953-11-09 1956-12-05 Dow Chemical Co Alpha-amino-beta-alkoxy-propionamides
FR1467942A (fr) * 1965-12-23 1967-02-03 Procédé de préparation de dérivés nu-disubstitués de l'aminoacétamide et nouveaux dérivés de ce type
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
WO1987003875A1 (en) * 1985-12-26 1987-07-02 Eisai Co., Ltd. Cephalosporin derivatives
JPH0796502B2 (ja) * 1986-06-16 1995-10-18 東レ株式会社 アミド基の加水分解方法
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0333154A3 (de) 1991-10-09
HU215925B (hu) 1999-03-29
PT90022B (pt) 1994-05-31
EP0333154A2 (de) 1989-09-20
PT90022A (pt) 1989-11-10
CN1036769A (zh) 1989-11-01
EP0612751A3 (en) 1994-09-21
GR890100162A (en) 1990-01-19
EP0764648A1 (de) 1997-03-26
DE68928174D1 (de) 1997-08-21
YU46998B (sh) 1994-11-15
GR1000462B (el) 1992-07-30
US5128465A (en) 1992-07-07
ATE212027T1 (de) 2002-02-15
ES2013403A6 (es) 1990-05-01
YU54189A (en) 1990-12-31
HUT50345A (en) 1990-01-29
EP0333154B1 (de) 1997-07-16
DE68929368T2 (de) 2002-08-14
DE68928174T2 (de) 1997-12-18
EP0764648B1 (de) 2002-01-16
EP0612751A2 (de) 1994-08-31
JPH07179472A (ja) 1995-07-18
CN1022837C (zh) 1993-11-24
DE68929368D1 (de) 2002-02-21
CA1339738C (en) 1998-03-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee