PT90022A - Processo para a preparacao de derivados cefem e dos intermediarios correspondentes - Google Patents

Processo para a preparacao de derivados cefem e dos intermediarios correspondentes

Info

Publication number
PT90022A
PT90022A PT90022A PT9002289A PT90022A PT 90022 A PT90022 A PT 90022A PT 90022 A PT90022 A PT 90022A PT 9002289 A PT9002289 A PT 9002289A PT 90022 A PT90022 A PT 90022A
Authority
PT
Portugal
Prior art keywords
sub
preparation
compound
intermediaries
cefem derivatives
Prior art date
Application number
PT90022A
Other languages
English (en)
Other versions
PT90022B (pt
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of PT90022A publication Critical patent/PT90022A/pt
Publication of PT90022B publication Critical patent/PT90022B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
PT90022A 1988-03-16 1989-03-16 Processo para a preparacao de derivados cefem e dos intermediarios correspondentes PT90022B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6051188 1988-03-16

Publications (2)

Publication Number Publication Date
PT90022A true PT90022A (pt) 1989-11-10
PT90022B PT90022B (pt) 1994-05-31

Family

ID=13144412

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90022A PT90022B (pt) 1988-03-16 1989-03-16 Processo para a preparacao de derivados cefem e dos intermediarios correspondentes

Country Status (12)

Country Link
US (1) US5128465A (pt)
EP (3) EP0764648B1 (pt)
JP (1) JPH07179472A (pt)
CN (1) CN1022837C (pt)
AT (2) ATE212027T1 (pt)
CA (1) CA1339738C (pt)
DE (2) DE68929368T2 (pt)
ES (1) ES2013403A6 (pt)
GR (1) GR1000462B (pt)
HU (1) HU215925B (pt)
PT (1) PT90022B (pt)
YU (1) YU46998B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69004921T2 (de) * 1989-09-30 1994-05-05 Eisai Co Ltd Injizierbare Cephalosporinpräparate und ihre Anwendung.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
KR950014571B1 (ko) * 1991-11-18 1995-12-08 제일제당주식회사 세펨 유도체의 제조방법
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
FR2722790B1 (fr) 1994-07-19 1996-10-04 Roussel Uclaf Nouvelles cephalosporines comportant en position 7 un radical benzyloxymino subtitue, leur procede de preparation leur application comme medicaments
JPH08151354A (ja) 1994-11-29 1996-06-11 Eisai Kagaku Kk アミノアセトアミド誘導体の製造法
KR0174117B1 (ko) * 1995-12-28 1999-02-01 윤원영 새로운 세팔로스포린 유도체 및 그 제조방법
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
CA2216259A1 (en) * 1996-09-25 1998-03-25 Eisai Chemical Co., Ltd. Production process of cephem compound
TR200003807T2 (tr) * 1998-06-22 2001-06-21 Basilea Pharmaceutica Ag Propenil sefalosporin türevleri
KR100441901B1 (ko) * 2001-07-02 2004-07-27 일동제약주식회사 세팔로스포린 유도체의 개선된 제조방법
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
CN103724330B (zh) 2005-12-07 2015-08-19 巴斯利尔药物股份公司 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用
CN105418641B (zh) * 2015-12-30 2018-08-10 广东金城金素制药有限公司 一种原研制品质头孢曲松钠及其药物制剂
WO2018185211A1 (en) 2017-04-06 2018-10-11 Syngenta Participations Ag Microbiocidal oxadiazole derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB762850A (en) * 1953-11-09 1956-12-05 Dow Chemical Co Alpha-amino-beta-alkoxy-propionamides
FR1467942A (fr) * 1965-12-23 1967-02-03 Procédé de préparation de dérivés nu-disubstitués de l'aminoacétamide et nouveaux dérivés de ce type
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
ATE114657T1 (de) * 1985-12-26 1994-12-15 Eisai Co Ltd Cephalosporin-verbindungen.
JPH0796502B2 (ja) * 1986-06-16 1995-10-18 東レ株式会社 アミド基の加水分解方法
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ATE212027T1 (de) 2002-02-15
EP0612751A2 (en) 1994-08-31
US5128465A (en) 1992-07-07
EP0764648A1 (en) 1997-03-26
DE68928174D1 (de) 1997-08-21
EP0764648B1 (en) 2002-01-16
JPH07179472A (ja) 1995-07-18
CN1036769A (zh) 1989-11-01
EP0333154A3 (en) 1991-10-09
DE68929368D1 (de) 2002-02-21
EP0333154B1 (en) 1997-07-16
DE68929368T2 (de) 2002-08-14
CA1339738C (en) 1998-03-17
HU215925B (hu) 1999-03-29
DE68928174T2 (de) 1997-12-18
CN1022837C (zh) 1993-11-24
EP0333154A2 (en) 1989-09-20
YU46998B (sh) 1994-11-15
YU54189A (en) 1990-12-31
ATE155469T1 (de) 1997-08-15
ES2013403A6 (es) 1990-05-01
GR890100162A (en) 1990-01-19
GR1000462B (el) 1992-07-30
HUT50345A (en) 1990-01-29
PT90022B (pt) 1994-05-31
EP0612751A3 (en) 1994-09-21

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19931118

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040531