ATE130040T1 - Verfahren zur herstellung von (-)-(2r,3s)-2,3- epoxy-3-(4-methoxyphenyl)propionat-methylester. - Google Patents

Verfahren zur herstellung von (-)-(2r,3s)-2,3- epoxy-3-(4-methoxyphenyl)propionat-methylester.

Info

Publication number
ATE130040T1
ATE130040T1 AT92400268T AT92400268T ATE130040T1 AT E130040 T1 ATE130040 T1 AT E130040T1 AT 92400268 T AT92400268 T AT 92400268T AT 92400268 T AT92400268 T AT 92400268T AT E130040 T1 ATE130040 T1 AT E130040T1
Authority
AT
Austria
Prior art keywords
methoxyphenyl
epoxy
producing
methyl ester
propionate methyl
Prior art date
Application number
AT92400268T
Other languages
English (en)
Inventor
Lydia Zard
Arlette Tixidre
Guy Rossey
Alexander Wick
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9409484&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE130040(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of ATE130040T1 publication Critical patent/ATE130040T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT92400268T 1991-02-08 1992-02-03 Verfahren zur herstellung von (-)-(2r,3s)-2,3- epoxy-3-(4-methoxyphenyl)propionat-methylester. ATE130040T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919101427A FR2672600B1 (fr) 1991-02-08 1991-02-08 Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.

Publications (1)

Publication Number Publication Date
ATE130040T1 true ATE130040T1 (de) 1995-11-15

Family

ID=9409484

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92400268T ATE130040T1 (de) 1991-02-08 1992-02-03 Verfahren zur herstellung von (-)-(2r,3s)-2,3- epoxy-3-(4-methoxyphenyl)propionat-methylester.

Country Status (9)

Country Link
US (1) US5169779A (de)
EP (1) EP0498706B2 (de)
JP (1) JP3126056B2 (de)
AT (1) ATE130040T1 (de)
DE (1) DE69205851T2 (de)
DK (1) DK0498706T3 (de)
ES (1) ES2082391T3 (de)
FR (1) FR2672600B1 (de)
GR (1) GR3018311T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1249777B (it) 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
ES2050067B1 (es) * 1992-06-08 1994-12-16 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil) propionico por transesterificacion enantioselectiva con un alcohol bifuncional catalizada enzimaticamente en medio organico.
WO1993025704A1 (en) * 1992-06-08 1993-12-23 Laboratorios Menarini S.A. A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective transesterification in an organic solvent
ES2048653B1 (es) * 1992-06-08 1994-12-16 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil) propionico por transesterificacion enantioselectiva catalizada enzimaticamente en un disolvente organico.
NL9202208A (nl) * 1992-12-18 1994-07-18 Dsm Nv Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters.
FI93741C (fi) * 1993-03-24 1995-05-26 Orion Yhtymae Oy Menetelmä optisesti puhtaitten (2S,3S)- ja (2R,3R)-threo-alkyyli-2-hydroksi-3-(4-metoksifenyyli)-3-(2-X-fenyylitio)propionaattien tai vastaavien asyloitujen yhdisteiden valmistamiseksi
US5559229A (en) * 1995-06-01 1996-09-24 Acic (Canada) Inc. Method for the manufacture of benzothiazepine
AU7551998A (en) * 1997-06-11 1998-12-30 Tanabe Seiyaku Co., Ltd. Process for preparing optically active phenyloxirane compounds
IT1302261B1 (it) 1998-09-24 2000-09-05 Zambon Spa Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli
CN114874156A (zh) * 2022-06-20 2022-08-09 巨鑫生物制药股份有限公司 一种合成地尔硫卓中间体(2s)-顺-羟基内酰胺的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
IT1217765B (it) * 1988-06-02 1990-03-30 Montedison Spa Processo per la risoluzione enzimatica degli isomeri ottici di derivati racemi esterei dell,acido 3 mercapto 2 alchilpropionico
FI95931C (fi) * 1988-09-02 1996-04-10 Tanabe Seiyaku Co Menetelmä (2R,3S)-3-(4-metoksifenyyli)glysidiinihapon alemman alkyyliesterin valmistamiseksi

Also Published As

Publication number Publication date
JPH0576389A (ja) 1993-03-30
DK0498706T3 (da) 1996-02-12
JP3126056B2 (ja) 2001-01-22
GR3018311T3 (en) 1996-03-31
US5169779A (en) 1992-12-08
DE69205851T2 (de) 1996-05-23
ES2082391T3 (es) 1996-03-16
EP0498706A1 (de) 1992-08-12
FR2672600B1 (fr) 1994-10-14
FR2672600A1 (fr) 1992-08-14
EP0498706B1 (de) 1995-11-08
DE69205851D1 (de) 1995-12-14
EP0498706B2 (de) 2000-05-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties