DK0498706T3 - Fremgangsmåde til fremstilling af (-)-(2R,3S)-methyl-2,3-epoxy-3-(4-methoxyphenyl)propionat - Google Patents

Fremgangsmåde til fremstilling af (-)-(2R,3S)-methyl-2,3-epoxy-3-(4-methoxyphenyl)propionat

Info

Publication number
DK0498706T3
DK0498706T3 DK92400268.6T DK92400268T DK0498706T3 DK 0498706 T3 DK0498706 T3 DK 0498706T3 DK 92400268 T DK92400268 T DK 92400268T DK 0498706 T3 DK0498706 T3 DK 0498706T3
Authority
DK
Denmark
Prior art keywords
methoxyphenyl
propionate
epoxy
methyl
preparation
Prior art date
Application number
DK92400268.6T
Other languages
English (en)
Inventor
Guy Rossey
Lydia Zard
Arlette Tixidre
Alexander Wick
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9409484&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0498706(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of DK0498706T3 publication Critical patent/DK0498706T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92400268.6T 1991-02-08 1992-02-03 Fremgangsmåde til fremstilling af (-)-(2R,3S)-methyl-2,3-epoxy-3-(4-methoxyphenyl)propionat DK0498706T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919101427A FR2672600B1 (fr) 1991-02-08 1991-02-08 Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.

Publications (1)

Publication Number Publication Date
DK0498706T3 true DK0498706T3 (da) 1996-02-12

Family

ID=9409484

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92400268.6T DK0498706T3 (da) 1991-02-08 1992-02-03 Fremgangsmåde til fremstilling af (-)-(2R,3S)-methyl-2,3-epoxy-3-(4-methoxyphenyl)propionat

Country Status (9)

Country Link
US (1) US5169779A (da)
EP (1) EP0498706B2 (da)
JP (1) JP3126056B2 (da)
AT (1) ATE130040T1 (da)
DE (1) DE69205851T2 (da)
DK (1) DK0498706T3 (da)
ES (1) ES2082391T3 (da)
FR (1) FR2672600B1 (da)
GR (1) GR3018311T3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1249777B (it) 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
DE69316238D1 (de) * 1992-06-08 1998-02-12 Menarini Lab Verfahren zur herstellung von s-(+)-2-(-3benzoylphenyl)propionsäure durch enzym katalysierte enanthioselektieve umesterung in einem organischen lösungsmittel.
ES2048653B1 (es) * 1992-06-08 1994-12-16 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil) propionico por transesterificacion enantioselectiva catalizada enzimaticamente en un disolvente organico.
ES2050067B1 (es) * 1992-06-08 1994-12-16 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil) propionico por transesterificacion enantioselectiva con un alcohol bifuncional catalizada enzimaticamente en medio organico.
NL9202208A (nl) * 1992-12-18 1994-07-18 Dsm Nv Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters.
FI93741C (fi) * 1993-03-24 1995-05-26 Orion Yhtymae Oy Menetelmä optisesti puhtaitten (2S,3S)- ja (2R,3R)-threo-alkyyli-2-hydroksi-3-(4-metoksifenyyli)-3-(2-X-fenyylitio)propionaattien tai vastaavien asyloitujen yhdisteiden valmistamiseksi
US5559229A (en) * 1995-06-01 1996-09-24 Acic (Canada) Inc. Method for the manufacture of benzothiazepine
CN1266430A (zh) * 1997-06-11 2000-09-13 田边制药株式会社 制备光学活性的苯基环氧乙烷化合物的方法
IT1302261B1 (it) 1998-09-24 2000-09-05 Zambon Spa Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli
CN114874156A (zh) * 2022-06-20 2022-08-09 巨鑫生物制药股份有限公司 一种合成地尔硫卓中间体(2s)-顺-羟基内酰胺的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
IT1217765B (it) * 1988-06-02 1990-03-30 Montedison Spa Processo per la risoluzione enzimatica degli isomeri ottici di derivati racemi esterei dell,acido 3 mercapto 2 alchilpropionico
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters

Also Published As

Publication number Publication date
ES2082391T3 (es) 1996-03-16
EP0498706B2 (fr) 2000-05-31
EP0498706B1 (fr) 1995-11-08
US5169779A (en) 1992-12-08
FR2672600B1 (fr) 1994-10-14
JPH0576389A (ja) 1993-03-30
GR3018311T3 (en) 1996-03-31
JP3126056B2 (ja) 2001-01-22
EP0498706A1 (fr) 1992-08-12
DE69205851T2 (de) 1996-05-23
DE69205851D1 (de) 1995-12-14
FR2672600A1 (fr) 1992-08-14
ATE130040T1 (de) 1995-11-15

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