IT1302261B1 - Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli - Google Patents

Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli

Info

Publication number
IT1302261B1
IT1302261B1 IT1998MI002061A ITMI982061A IT1302261B1 IT 1302261 B1 IT1302261 B1 IT 1302261B1 IT 1998MI002061 A IT1998MI002061 A IT 1998MI002061A IT MI982061 A ITMI982061 A IT MI982061A IT 1302261 B1 IT1302261 B1 IT 1302261B1
Authority
IT
Italy
Prior art keywords
phenylglycidates
transesterification
alcohols
amino
kinetic resolution
Prior art date
Application number
IT1998MI002061A
Other languages
English (en)
Inventor
Marco Villa
Dario Tentorio
Angelo Restelli
Sergio Riva
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT1998MI002061A priority Critical patent/IT1302261B1/it
Priority to US09/399,962 priority patent/US6187936B1/en
Priority to PCT/EP1999/006940 priority patent/WO2000017384A1/en
Priority to EP99947386A priority patent/EP1115881B1/en
Priority to ES99947386T priority patent/ES2249027T3/es
Priority to JP2000574283A priority patent/JP4225694B2/ja
Priority to DE69924510T priority patent/DE69924510T2/de
Priority to AT99947386T priority patent/ATE292189T1/de
Publication of ITMI982061A1 publication Critical patent/ITMI982061A1/it
Application granted granted Critical
Publication of IT1302261B1 publication Critical patent/IT1302261B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
IT1998MI002061A 1998-09-24 1998-09-24 Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli IT1302261B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1998MI002061A IT1302261B1 (it) 1998-09-24 1998-09-24 Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli
US09/399,962 US6187936B1 (en) 1998-09-24 1999-09-20 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
PCT/EP1999/006940 WO2000017384A1 (en) 1998-09-24 1999-09-20 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
EP99947386A EP1115881B1 (en) 1998-09-24 1999-09-20 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
ES99947386T ES2249027T3 (es) 1998-09-24 1999-09-20 Proceso para la resolucion cinetica enzimatica de 3-fenilglicidatos por transesterificacion con aminoalcoholes.
JP2000574283A JP4225694B2 (ja) 1998-09-24 1999-09-20 アミノアルコール類とのエステル交換による3−フェニルグリシド酸エステル類の酵素的速度論的分割方法
DE69924510T DE69924510T2 (de) 1998-09-24 1999-09-20 Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen
AT99947386T ATE292189T1 (de) 1998-09-24 1999-09-20 Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002061A IT1302261B1 (it) 1998-09-24 1998-09-24 Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli

Publications (2)

Publication Number Publication Date
ITMI982061A1 ITMI982061A1 (it) 2000-03-24
IT1302261B1 true IT1302261B1 (it) 2000-09-05

Family

ID=11380751

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002061A IT1302261B1 (it) 1998-09-24 1998-09-24 Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli

Country Status (8)

Country Link
US (1) US6187936B1 (it)
EP (1) EP1115881B1 (it)
JP (1) JP4225694B2 (it)
AT (1) ATE292189T1 (it)
DE (1) DE69924510T2 (it)
ES (1) ES2249027T3 (it)
IT (1) IT1302261B1 (it)
WO (1) WO2000017384A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002227796A1 (en) * 2002-02-06 2003-09-02 Commonwealth Scientific And Industrial Research Organisation Esterases with lipase activity
GB0306267D0 (en) 2003-03-19 2003-04-23 Ineos Fluor Ltd Process
CN102276485B (zh) * 2011-06-20 2014-03-12 安徽巨成精细化工有限公司 一种丙烯酸二甲氨基乙酯的生产方法
CN114874156A (zh) * 2022-06-20 2022-08-09 巨鑫生物制药股份有限公司 一种合成地尔硫卓中间体(2s)-顺-羟基内酰胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236647A (en) 1968-06-13 1971-06-23 Russell John Searle Seating in powered vehicles
US4567175A (en) 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4594342A (en) 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
GB2167063A (en) 1984-11-17 1986-05-21 Tanabe Seiyaku Co 6 or 9-chloro-1, 5-benzothiazepine derivatives
IT1249777B (it) 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
FR2672600B1 (fr) 1991-02-08 1994-10-14 Synthelabo Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.
NL9202208A (nl) 1992-12-18 1994-07-18 Dsm Nv Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters.
NL1005338C2 (nl) 1997-02-21 1998-08-24 Dsm Nv Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat.

Also Published As

Publication number Publication date
DE69924510T2 (de) 2006-02-16
ATE292189T1 (de) 2005-04-15
ES2249027T3 (es) 2006-03-16
DE69924510D1 (de) 2005-05-04
US6187936B1 (en) 2001-02-13
WO2000017384A1 (en) 2000-03-30
JP2002526086A (ja) 2002-08-20
ITMI982061A1 (it) 2000-03-24
EP1115881B1 (en) 2005-03-30
EP1115881A1 (en) 2001-07-18
JP4225694B2 (ja) 2009-02-18

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Legal Events

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0001 Granted