DE69924510D1 - Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen - Google Patents

Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen

Info

Publication number
DE69924510D1
DE69924510D1 DE69924510T DE69924510T DE69924510D1 DE 69924510 D1 DE69924510 D1 DE 69924510D1 DE 69924510 T DE69924510 T DE 69924510T DE 69924510 T DE69924510 T DE 69924510T DE 69924510 D1 DE69924510 D1 DE 69924510D1
Authority
DE
Germany
Prior art keywords
phenyl
procedure
treatment
amino alcohols
enzymatic kinetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69924510T
Other languages
English (en)
Other versions
DE69924510T2 (de
Inventor
Marco Villa
Dario Tentorio
Angelo Restelli
Sergio Riva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zach System SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Application granted granted Critical
Publication of DE69924510D1 publication Critical patent/DE69924510D1/de
Publication of DE69924510T2 publication Critical patent/DE69924510T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
DE69924510T 1998-09-24 1999-09-20 Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen Expired - Lifetime DE69924510T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1998MI002061A IT1302261B1 (it) 1998-09-24 1998-09-24 Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli
ITMI982061 1998-09-24
PCT/EP1999/006940 WO2000017384A1 (en) 1998-09-24 1999-09-20 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols

Publications (2)

Publication Number Publication Date
DE69924510D1 true DE69924510D1 (de) 2005-05-04
DE69924510T2 DE69924510T2 (de) 2006-02-16

Family

ID=11380751

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924510T Expired - Lifetime DE69924510T2 (de) 1998-09-24 1999-09-20 Verfahren zur enzymatischen kinetischen trennung von 3-phenylglycidsäure durch umesterung mittels aminoalkoholen

Country Status (8)

Country Link
US (1) US6187936B1 (de)
EP (1) EP1115881B1 (de)
JP (1) JP4225694B2 (de)
AT (1) ATE292189T1 (de)
DE (1) DE69924510T2 (de)
ES (1) ES2249027T3 (de)
IT (1) IT1302261B1 (de)
WO (1) WO2000017384A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1617931A (zh) * 2002-02-06 2005-05-18 联邦科学技术研究组织 具有脂肪酶活性的酯酶
GB0306267D0 (en) 2003-03-19 2003-04-23 Ineos Fluor Ltd Process
CN102276485B (zh) * 2011-06-20 2014-03-12 安徽巨成精细化工有限公司 一种丙烯酸二甲氨基乙酯的生产方法
CN114874156A (zh) * 2022-06-20 2022-08-09 巨鑫生物制药股份有限公司 一种合成地尔硫卓中间体(2s)-顺-羟基内酰胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236647A (en) 1968-06-13 1971-06-23 Russell John Searle Seating in powered vehicles
US4567175A (en) 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4594342A (en) 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
GB2167063A (en) 1984-11-17 1986-05-21 Tanabe Seiyaku Co 6 or 9-chloro-1, 5-benzothiazepine derivatives
IT1249777B (it) * 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
FR2672600B1 (fr) * 1991-02-08 1994-10-14 Synthelabo Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.
NL9202208A (nl) * 1992-12-18 1994-07-18 Dsm Nv Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters.
NL1005338C2 (nl) * 1997-02-21 1998-08-24 Dsm Nv Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat.

Also Published As

Publication number Publication date
JP2002526086A (ja) 2002-08-20
JP4225694B2 (ja) 2009-02-18
EP1115881B1 (de) 2005-03-30
ATE292189T1 (de) 2005-04-15
DE69924510T2 (de) 2006-02-16
IT1302261B1 (it) 2000-09-05
ES2249027T3 (es) 2006-03-16
ITMI982061A1 (it) 2000-03-24
EP1115881A1 (de) 2001-07-18
WO2000017384A1 (en) 2000-03-30
US6187936B1 (en) 2001-02-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZACH SYSTEM S.P.A., BRESSO, (MILANO), IT