DE69112716D1 - Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung. - Google Patents

Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung.

Info

Publication number
DE69112716D1
DE69112716D1 DE69112716T DE69112716T DE69112716D1 DE 69112716 D1 DE69112716 D1 DE 69112716D1 DE 69112716 T DE69112716 T DE 69112716T DE 69112716 T DE69112716 T DE 69112716T DE 69112716 D1 DE69112716 D1 DE 69112716D1
Authority
DE
Germany
Prior art keywords
compound
hydroxyvitamin
biological production
vitamin
microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69112716T
Other languages
English (en)
Other versions
DE69112716T2 (de
Inventor
Koji Takeda
Kiyoshi Kimura
Kazuhiko Okamura
Rokuro Okamoto
Joji Sasaki
Takashi Adachi
Sadafumi Omura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mercian Corp
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Publication of DE69112716D1 publication Critical patent/DE69112716D1/de
Application granted granted Critical
Publication of DE69112716T2 publication Critical patent/DE69112716T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69112716T 1990-06-15 1991-06-14 Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung. Expired - Fee Related DE69112716T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15705490 1990-06-15
JP33428390A JP3201411B2 (ja) 1990-06-15 1990-11-30 ビタミンｄ類の生物学的製造方法

Publications (2)

Publication Number Publication Date
DE69112716D1 true DE69112716D1 (de) 1995-10-12
DE69112716T2 DE69112716T2 (de) 1996-02-01

Family

ID=26484632

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69112716T Expired - Fee Related DE69112716T2 (de) 1990-06-15 1991-06-14 Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung.

Country Status (9)

Country Link
US (1) US5474923A (de)
EP (1) EP0461921B1 (de)
JP (1) JP3201411B2 (de)
KR (1) KR100190412B1 (de)
AT (1) ATE127523T1 (de)
CA (1) CA2044550C (de)
DE (1) DE69112716T2 (de)
ES (1) ES2079573T3 (de)
TW (1) TW234147B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンｄ類の生物学的製造方法
AU4357493A (en) * 1992-06-25 1994-01-24 Taisho Pharmaceutical Co., Ltd. Vitamin d hydroxylase gene
US6146844A (en) * 1995-08-28 2000-11-14 Mercian Corporation Process for producing hydroxylated cholesterols and dihydroxycholesterols using amycolata
WO2000061776A1 (fr) * 1999-04-14 2000-10-19 Mercian Corporation Derives de vitamine d et procede de production correspondant
US20030191093A1 (en) * 2001-12-03 2003-10-09 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
AU2005207786B2 (en) * 2004-01-29 2010-11-25 Eisai R & D Management Co., Ltd Method of stabilizing macrolide compound
CN101405249B (zh) 2006-03-15 2013-05-29 日本迈科洛生物制药有限公司 茚衍生物的制备方法及其制备中间体
ES2446668T3 (es) * 2008-12-19 2014-03-10 Ildong Pharmaceutical Co., Ltd. Composición de tampón para catalizar la preparación de calcitriol o calcifediol y método para preparar calcitriol o calcifediol usando esta

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
JPH0717686B2 (ja) * 1986-08-08 1995-03-01 メルシャン株式会社 部分メチル化シクロデキストリン及びその製造方法
US4892821A (en) * 1987-07-08 1990-01-09 Taisho Pharmaceutical Co., Ltd. Method for preparing vitamin D compounds
JP2663294B2 (ja) * 1989-03-04 1997-10-15 メルシャン株式会社 ビタミンｄ類の製造方法
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンｄ類の生物学的製造方法

Also Published As

Publication number Publication date
KR920000934A (ko) 1992-01-29
KR100190412B1 (ko) 1999-06-01
CA2044550C (en) 2000-09-26
EP0461921B1 (de) 1995-09-06
JPH04166090A (ja) 1992-06-11
US5474923A (en) 1995-12-12
EP0461921A2 (de) 1991-12-18
CA2044550A1 (en) 1991-12-16
EP0461921A3 (en) 1992-05-20
ATE127523T1 (de) 1995-09-15
TW234147B (de) 1994-11-11
DE69112716T2 (de) 1996-02-01
JP3201411B2 (ja) 2001-08-20
ES2079573T3 (es) 1996-01-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee