DE3774954D1 - Verfahren zur herstellung von penemen. - Google Patents

Verfahren zur herstellung von penemen.

Info

Publication number
DE3774954D1
DE3774954D1 DE8787306586T DE3774954T DE3774954D1 DE 3774954 D1 DE3774954 D1 DE 3774954D1 DE 8787306586 T DE8787306586 T DE 8787306586T DE 3774954 T DE3774954 T DE 3774954T DE 3774954 D1 DE3774954 D1 DE 3774954D1
Authority
DE
Germany
Prior art keywords
penemes
producing
dithiabicyclo
penems
azetidinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787306586T
Other languages
English (en)
Inventor
Catherine Elizabeth Brighty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3774954D1 publication Critical patent/DE3774954D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Paints Or Removers (AREA)
  • Control Of El Displays (AREA)
  • Pens And Brushes (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
  • Steroid Compounds (AREA)
DE8787306586T 1986-07-29 1987-07-24 Verfahren zur herstellung von penemen. Expired - Fee Related DE3774954D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/891,493 US4695626A (en) 1986-07-29 1986-07-29 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters

Publications (1)

Publication Number Publication Date
DE3774954D1 true DE3774954D1 (de) 1992-01-16

Family

ID=25398284

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787306586T Expired - Fee Related DE3774954D1 (de) 1986-07-29 1987-07-24 Verfahren zur herstellung von penemen.

Country Status (18)

Country Link
US (2) US4695626A (de)
EP (1) EP0255307B1 (de)
JP (1) JPH0737462B2 (de)
KR (1) KR890004581B1 (de)
AT (1) ATE70064T1 (de)
AU (1) AU583465B2 (de)
CA (1) CA1285275C (de)
DE (1) DE3774954D1 (de)
DK (1) DK170169B1 (de)
ES (1) ES2038665T3 (de)
FI (1) FI87651C (de)
GR (1) GR3003660T3 (de)
HU (1) HU198068B (de)
IE (1) IE60029B1 (de)
IL (1) IL83304A (de)
NZ (1) NZ221201A (de)
PT (1) PT85407B (de)
ZA (1) ZA875541B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1221358A (en) * 1982-12-08 1987-05-05 Erba Farmitalia 2-THIACEPHEM AND (5R)-PENEM DERIVATIVES
US4782145A (en) * 1986-06-02 1988-11-01 Pfizer Inc. Process for penem derivatives
US4751297A (en) * 1987-03-20 1988-06-14 Pfizer Inc. Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate
WO1988008845A1 (en) * 1987-05-11 1988-11-17 Pfizer Inc. Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
US5191077A (en) * 1987-05-11 1993-03-02 Pfizer Inc. Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
DE19512050A1 (de) * 1995-03-31 1996-10-02 Gimmy Lindomare Dr Vorrichtung zum Sichern von Schrauben vor unbefugtem Zugriff
WO2005113592A2 (en) * 2004-05-19 2005-12-01 Maxygen, Inc. Interferon-alpha polypeptides and conjugates
WO2009029554A2 (en) 2007-08-24 2009-03-05 Codexis, Inc. Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
WO2018071358A1 (en) 2016-10-10 2018-04-19 The Johns Hopkins University Antibacterial agents against d,d- and l,d-transpeptidases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH541577A (de) * 1970-11-03 1973-09-15 Ciba Geigy Ag Verfahren zur Herstellung thiaheterocyclischer Verbindungen
ATE21105T1 (de) * 1980-11-06 1986-08-15 Hoechst Uk Ltd 7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.
JPS57176988A (en) * 1981-04-09 1982-10-30 Sankyo Co Ltd Penam-3-carboxylic acid derivative and its preparation
CA1221358A (en) * 1982-12-08 1987-05-05 Erba Farmitalia 2-THIACEPHEM AND (5R)-PENEM DERIVATIVES
GB2131432B (en) * 1982-12-08 1986-10-15 Erba Farmitalia Preparation of (5r)-penem derivatives
EP0115308A3 (de) * 1983-01-25 1984-10-10 Merck & Co. Inc. 2-Ungesättigte Alkylthio-Pen-2-em-3-Carbonsäuren und Verfahren zur Herstellung von substituierten 2-Thioxopenamen und 2-substituierten Thiopenemen
DE3464610D1 (de) * 1983-06-21 1987-08-13 Pfizer 2-alkylthiopenem derivatives
EP0132101A1 (de) * 1983-07-14 1985-01-23 Pfizer Inc. 2-Heterocycloalkylthiopenem-Derivate

Also Published As

Publication number Publication date
FI87651B (fi) 1992-10-30
JPS6341481A (ja) 1988-02-22
PT85407A (en) 1987-08-01
ZA875541B (en) 1989-03-29
KR880001668A (ko) 1988-04-26
HU198068B (en) 1989-07-28
JPH0737462B2 (ja) 1995-04-26
AU7618787A (en) 1988-02-04
IL83304A0 (en) 1987-12-31
EP0255307A1 (de) 1988-02-03
US4695626A (en) 1987-09-22
GR3003660T3 (de) 1993-03-16
US4782146A (en) 1988-11-01
FI873290A (fi) 1988-01-30
DK392287D0 (da) 1987-07-28
KR890004581B1 (ko) 1989-11-16
IE872046L (en) 1988-01-29
CA1285275C (en) 1991-06-25
IE60029B1 (en) 1994-05-18
HUT45067A (en) 1988-05-30
IL83304A (en) 1992-06-21
DK392287A (da) 1988-01-30
NZ221201A (en) 1990-06-26
FI87651C (fi) 1993-02-10
ATE70064T1 (de) 1991-12-15
EP0255307B1 (de) 1991-12-04
FI873290A0 (fi) 1987-07-28
DK170169B1 (da) 1995-06-06
AU583465B2 (en) 1989-04-27
PT85407B (pt) 1990-04-30
ES2038665T3 (es) 1993-08-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee