IL83304A - Process for the synthesis of penem allyl esters - Google Patents

Process for the synthesis of penem allyl esters

Info

Publication number
IL83304A
IL83304A IL83304A IL8330487A IL83304A IL 83304 A IL83304 A IL 83304A IL 83304 A IL83304 A IL 83304A IL 8330487 A IL8330487 A IL 8330487A IL 83304 A IL83304 A IL 83304A
Authority
IL
Israel
Prior art keywords
synthesis
penem
allyl esters
esters
allyl
Prior art date
Application number
IL83304A
Other languages
English (en)
Other versions
IL83304A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL83304A0 publication Critical patent/IL83304A0/xx
Publication of IL83304A publication Critical patent/IL83304A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pens And Brushes (AREA)
  • Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Paints Or Removers (AREA)
  • Control Of El Displays (AREA)
IL83304A 1986-07-29 1987-07-23 Process for the synthesis of penem allyl esters IL83304A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/891,493 US4695626A (en) 1986-07-29 1986-07-29 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters

Publications (2)

Publication Number Publication Date
IL83304A0 IL83304A0 (en) 1987-12-31
IL83304A true IL83304A (en) 1992-06-21

Family

ID=25398284

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83304A IL83304A (en) 1986-07-29 1987-07-23 Process for the synthesis of penem allyl esters

Country Status (18)

Country Link
US (2) US4695626A (de)
EP (1) EP0255307B1 (de)
JP (1) JPH0737462B2 (de)
KR (1) KR890004581B1 (de)
AT (1) ATE70064T1 (de)
AU (1) AU583465B2 (de)
CA (1) CA1285275C (de)
DE (1) DE3774954D1 (de)
DK (1) DK170169B1 (de)
ES (1) ES2038665T3 (de)
FI (1) FI87651C (de)
GR (1) GR3003660T3 (de)
HU (1) HU198068B (de)
IE (1) IE60029B1 (de)
IL (1) IL83304A (de)
NZ (1) NZ221201A (de)
PT (1) PT85407B (de)
ZA (1) ZA875541B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1221358A (en) * 1982-12-08 1987-05-05 Erba Farmitalia 2-thiacephems and (5r) penems derivatives
US4782145A (en) * 1986-06-02 1988-11-01 Pfizer Inc. Process for penem derivatives
US4751297A (en) * 1987-03-20 1988-06-14 Pfizer Inc. Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate
US5013729A (en) * 1987-05-11 1991-05-07 Pfizer Inc. Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
US5191077A (en) * 1987-05-11 1993-03-02 Pfizer Inc. Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
DE19512050A1 (de) * 1995-03-31 1996-10-02 Gimmy Lindomare Dr Vorrichtung zum Sichern von Schrauben vor unbefugtem Zugriff
JP2008507298A (ja) * 2004-05-19 2008-03-13 マキシジェン， インコーポレイテッド インターフェロンαポリペプチドおよび結合体
WO2009029554A2 (en) * 2007-08-24 2009-03-05 Codexis, Inc. Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
CN110062760A (zh) * 2016-10-10 2019-07-26 约翰霍普金斯大学 抗d,d-转肽酶和l,d-转肽酶的抗细菌剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH541576A (de) * 1970-11-03 1973-09-15 Ciba Geigy Ag Verfahren zur Herstellung thiaheterocyclischer Verbindungen
ATE21105T1 (de) * 1980-11-06 1986-08-15 Hoechst Uk Ltd 7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.
JPS57176988A (en) * 1981-04-09 1982-10-30 Sankyo Co Ltd Penam-3-carboxylic acid derivative and its preparation
GB2131432B (en) * 1982-12-08 1986-10-15 Erba Farmitalia Preparation of (5r)-penem derivatives
CA1221358A (en) * 1982-12-08 1987-05-05 Erba Farmitalia 2-thiacephems and (5r) penems derivatives
EP0115308A3 (de) * 1983-01-25 1984-10-10 Merck & Co. Inc. 2-Ungesättigte Alkylthio-Pen-2-em-3-Carbonsäuren und Verfahren zur Herstellung von substituierten 2-Thioxopenamen und 2-substituierten Thiopenemen
DE3464610D1 (de) * 1983-06-21 1987-08-13 Pfizer 2-alkylthiopenem derivatives
EP0132101A1 (de) * 1983-07-14 1985-01-23 Pfizer Inc. 2-Heterocycloalkylthiopenem-Derivate

Also Published As

Publication number Publication date
GR3003660T3 (de) 1993-03-16
KR890004581B1 (ko) 1989-11-16
EP0255307A1 (de) 1988-02-03
FI87651C (fi) 1993-02-10
DK392287A (da) 1988-01-30
FI873290A0 (fi) 1987-07-28
ZA875541B (en) 1989-03-29
DK392287D0 (da) 1987-07-28
DK170169B1 (da) 1995-06-06
NZ221201A (en) 1990-06-26
JPS6341481A (ja) 1988-02-22
ATE70064T1 (de) 1991-12-15
CA1285275C (en) 1991-06-25
DE3774954D1 (de) 1992-01-16
PT85407A (en) 1987-08-01
US4695626A (en) 1987-09-22
AU583465B2 (en) 1989-04-27
HU198068B (en) 1989-07-28
FI873290A7 (fi) 1988-01-30
IL83304A0 (en) 1987-12-31
IE872046L (en) 1988-01-29
FI87651B (fi) 1992-10-30
PT85407B (pt) 1990-04-30
HUT45067A (en) 1988-05-30
EP0255307B1 (de) 1991-12-04
US4782146A (en) 1988-11-01
ES2038665T3 (es) 1993-08-01
IE60029B1 (en) 1994-05-18
AU7618787A (en) 1988-02-04
JPH0737462B2 (ja) 1995-04-26
KR880001668A (ko) 1988-04-26

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Legal Events

Date Code Title Description
RH Patent void