ES2079573T3 - Metodo para la preparacion biologica de compuestos hidroxivitamina d. - Google Patents

Metodo para la preparacion biologica de compuestos hidroxivitamina d.

Info

Publication number
ES2079573T3
ES2079573T3 ES91305415T ES91305415T ES2079573T3 ES 2079573 T3 ES2079573 T3 ES 2079573T3 ES 91305415 T ES91305415 T ES 91305415T ES 91305415 T ES91305415 T ES 91305415T ES 2079573 T3 ES2079573 T3 ES 2079573T3
Authority
ES
Spain
Prior art keywords
hydroxivitamine
compounds
biological preparation
compound
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91305415T
Other languages
English (en)
Inventor
Koji Takeda
Kiyoshi Kimura
Kazuhiko Okamura
Rokuro Okamoto
Joji Sasaki
Takashi Adachi
Sadafumi Omura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mercian Corp
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Application granted granted Critical
Publication of ES2079573T3 publication Critical patent/ES2079573T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN METODO PARA INTRODUCIR GRUPOS HIDROXIL EN COMPUESTOS DE VITAMINA D EN LAS POSICIONES 1(ALFA)-Y/O 25 EN LA PRESENCIA DE UN COMPUESTO CICLODEXTRINA ES EFECTUADO MEDIANTE EL USO DE UNA REACCION DE MEZCLA CONTENIENDO UN MICROORGANISMO CAPAZ DE HIDROXILAR UN COMPUESTO DE VITAMINA D O UNA ENZIMA PRODUCIDA A PARTIR DEL MICROORGANISMO.
ES91305415T 1990-06-15 1991-06-14 Metodo para la preparacion biologica de compuestos hidroxivitamina d. Expired - Lifetime ES2079573T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15705490 1990-06-15
JP33428390A JP3201411B2 (ja) 1990-06-15 1990-11-30 ビタミンｄ類の生物学的製造方法

Publications (1)

Publication Number Publication Date
ES2079573T3 true ES2079573T3 (es) 1996-01-16

Family

ID=26484632

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91305415T Expired - Lifetime ES2079573T3 (es) 1990-06-15 1991-06-14 Metodo para la preparacion biologica de compuestos hidroxivitamina d.

Country Status (9)

Country Link
US (1) US5474923A (es)
EP (1) EP0461921B1 (es)
JP (1) JP3201411B2 (es)
KR (1) KR100190412B1 (es)
AT (1) ATE127523T1 (es)
CA (1) CA2044550C (es)
DE (1) DE69112716T2 (es)
ES (1) ES2079573T3 (es)
TW (1) TW234147B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンｄ類の生物学的製造方法
AU4357493A (en) * 1992-06-25 1994-01-24 Taisho Pharmaceutical Co., Ltd. Vitamin d hydroxylase gene
JP3742435B2 (ja) 1995-08-28 2006-02-01 メルシャン株式会社 生物学的変換によるヒドロキシル化コレステロールの製造方法およびジヒドロキシコレステロール
WO2000061776A1 (fr) * 1999-04-14 2000-10-19 Mercian Corporation Derives de vitamine d et procede de production correspondant
IL162213A0 (en) * 2001-12-03 2005-11-20 Novacea Inc Pharmaceutical compositions containing active vitamin d compounds
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7655442B2 (en) * 2004-01-29 2010-02-02 Eisai R&D Management Co., Ltd. Method for stabilizing macrolide compounds
WO2007105773A1 (ja) 2006-03-15 2007-09-20 Mercian Corporation インデン誘導体の製造方法およびその製造中間体
EP2377942B1 (en) * 2008-12-19 2013-11-20 Ildong Pharmaceutical Co., Ltd. Buffer composition for catalyzing the preparation of calcitriol or calcifediol and method for preparing calcitriol or calcifediol using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
JPH0717686B2 (ja) * 1986-08-08 1995-03-01 メルシャン株式会社 部分メチル化シクロデキストリン及びその製造方法
US4892821A (en) * 1987-07-08 1990-01-09 Taisho Pharmaceutical Co., Ltd. Method for preparing vitamin D compounds
JP2663294B2 (ja) * 1989-03-04 1997-10-15 メルシャン株式会社 ビタミンｄ類の製造方法
JP3201411B2 (ja) * 1990-06-15 2001-08-20 メルシャン株式会社 ビタミンｄ類の生物学的製造方法

Also Published As

Publication number Publication date
EP0461921A3 (en) 1992-05-20
TW234147B (es) 1994-11-11
EP0461921A2 (en) 1991-12-18
KR920000934A (ko) 1992-01-29
KR100190412B1 (ko) 1999-06-01
DE69112716D1 (de) 1995-10-12
ATE127523T1 (de) 1995-09-15
CA2044550A1 (en) 1991-12-16
JPH04166090A (ja) 1992-06-11
EP0461921B1 (en) 1995-09-06
CA2044550C (en) 2000-09-26
JP3201411B2 (ja) 2001-08-20
US5474923A (en) 1995-12-12
DE69112716T2 (de) 1996-02-01

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