AT396425B - Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen - Google Patents

Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen Download PDF

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Publication number
AT396425B
AT396425B AT0152591A AT152591A AT396425B AT 396425 B AT396425 B AT 396425B AT 0152591 A AT0152591 A AT 0152591A AT 152591 A AT152591 A AT 152591A AT 396425 B AT396425 B AT 396425B
Authority
AT
Austria
Prior art keywords
gel
particles
phase
mpa
active ingredient
Prior art date
Application number
AT0152591A
Other languages
German (de)
English (en)
Other versions
ATA152591A (de
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ATA152591A publication Critical patent/ATA152591A/de
Application granted granted Critical
Publication of AT396425B publication Critical patent/AT396425B/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Glanulating (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
AT0152591A 1990-08-01 1991-07-31 Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen AT396425B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ATA152591A ATA152591A (de) 1993-01-15
AT396425B true AT396425B (de) 1993-09-27

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0152591A AT396425B (de) 1990-08-01 1991-07-31 Verfahren zur herstellung von zusammensetzungen, die stoffe anhaltend abgeben und so erhaltene zusammensetzungen

Country Status (30)

Country Link
US (1) US5213812A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2818704B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR920003962A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT396425B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU649696B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE1004772A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2048270C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH682715A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE4125542A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK175756B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2046083B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI104149B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2665360B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB9016885D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR1001512B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK33294A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE65124B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN178446B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1251788B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU87982A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (1) MA22245A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY107500A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL194637C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO300158B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ238981A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA09387A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT98497B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE505734C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TN (1) TNSN91067A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA915565B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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HUT75469A (en) * 1994-02-28 1997-05-28 Medinova Med Consulting Gmbh Drug targeting system, method for preparing same and its use
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
AU4571097A (en) * 1996-10-09 1998-05-05 Takeda Chemical Industries Ltd. A method for producing a microparticle
TW577759B (en) * 1997-04-18 2004-03-01 Ipsen Pharma Biotech Sustained release compositions in the form of microcapsules or implants and the process for their preparation
WO1999052708A1 (en) 1998-04-13 1999-10-21 Luminex Corporation Liquid labeling with fluorescent microparticles
EA004502B1 (ru) * 1998-12-16 2004-04-29 Авентис Фармасьютикалз Инк. Фармацевтическая композиция антагониста рецептора серотонина и способ ее получения
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
EP1335661B1 (en) 2000-10-27 2009-05-06 Baxter Healthcare S.A. Production of microspheres
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
ATE395042T1 (de) * 2001-08-16 2008-05-15 Baxter Int Darreichungsformen welche mikropartikel und treibgas enthalten
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
KR101137785B1 (ko) * 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
US20050048127A1 (en) * 2003-07-22 2005-03-03 Larry Brown Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
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FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
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WO2005112885A2 (en) * 2004-05-12 2005-12-01 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
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CA2620167A1 (en) * 2005-08-23 2007-03-01 Altairnano, Inc. Highly photocatalytic phosphorus-doped anatase-tio2 composition and related manufacturing methods
WO2007103820A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Nanostructured indium-doped iron oxide
WO2007103824A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Nanostructured metal oxides
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US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
EP2647712A3 (en) 2006-08-04 2013-11-20 Baxter International Inc Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
WO2008060786A2 (en) * 2006-10-06 2008-05-22 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
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US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
WO2008128000A1 (en) * 2007-04-12 2008-10-23 Altairnano, Inc. Teflon replacements and related production methods
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US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
JP5685182B2 (ja) 2008-04-18 2015-03-18 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 初発自己免疫性糖尿病を予防するため、および／または逆転させるためのマイクロスフェアに基づく組成物
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EP0145240A2 (en) * 1983-11-04 1985-06-19 Takeda Chemical Industries, Ltd. Method for producing Microcapsule

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Also Published As

Publication number Publication date
ES2046083B1 (es) 1994-08-01
MA22245A1 (fr) 1992-04-01
SE9102249L (sv) 1992-02-02
SE505734C2 (sv) 1997-10-06
FR2665360A1 (fr) 1992-02-07
PT98497B (pt) 1997-10-31
IN178446B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-05-03
FR2665360B1 (fr) 1995-02-10
IE912700A1 (en) 1992-02-12
HK33294A (en) 1994-04-22
NO912986D0 (no) 1991-07-31
KR920003962A (ko) 1992-03-27
NO300158B1 (no) 1997-04-21
GB9016885D0 (en) 1990-09-12
FI104149B (fi) 1999-11-30
PT98497A (pt) 1992-06-30
JP2818704B2 (ja) 1998-10-30
GR910100330A (en) 1992-08-31
NL9101306A (nl) 1992-03-02
ZA915565B (en) 1992-04-29
CA2048270A1 (en) 1992-02-02
NZ238981A (en) 1992-11-25
MY107500A (en) 1995-12-30
ITMI911953A0 (it) 1991-07-15
US5213812A (en) 1993-05-25
AU666808B2 (en) 1996-02-22
NL194637C (nl) 2002-10-04
GR1001512B (el) 1994-02-28
DK141891A (da) 1992-02-02
SE9102249D0 (sv) 1991-07-26
TNSN91067A1 (fr) 1992-10-25
FI913646A0 (fi) 1991-07-31
AU8146691A (en) 1992-02-06
LU87982A1 (fr) 1992-04-15
ES2046083A1 (es) 1994-01-16
CA2048270C (en) 1997-02-25
BE1004772A3 (fr) 1993-01-26
DE4125542A1 (de) 1992-02-06
DK141891D0 (da) 1991-07-31
ATA152591A (de) 1993-01-15
AU5939394A (en) 1994-06-02
AU649696B2 (en) 1994-06-02
IT1251788B (it) 1995-05-26
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
JPH05178740A (ja) 1993-07-20
IE65124B1 (en) 1995-10-04
ITMI911953A1 (it) 1993-01-15
FI104149B1 (fi) 1999-11-30
OA09387A (fr) 1992-09-15
FI913646L (fi) 1992-02-02
DK175756B1 (da) 2005-02-14
CH682715A5 (fr) 1993-11-15

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