IT1251788B - Procedimento di preparazione di composizione a cessione protratta e le composizioni cosi' ottenute - Google Patents

Procedimento di preparazione di composizione a cessione protratta e le composizioni cosi' ottenute

Info

Publication number
IT1251788B
IT1251788B ITMI911953A ITMI911953A IT1251788B IT 1251788 B IT1251788 B IT 1251788B IT MI911953 A ITMI911953 A IT MI911953A IT MI911953 A ITMI911953 A IT MI911953A IT 1251788 B IT1251788 B IT 1251788B
Authority
IT
Italy
Prior art keywords
compositions
preparation
composition
particles
proposed sale
Prior art date
Application number
ITMI911953A
Other languages
English (en)
Inventor
Jean-Mare Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ITMI911953A0 publication Critical patent/ITMI911953A0/it
Publication of ITMI911953A1 publication Critical patent/ITMI911953A1/it
Application granted granted Critical
Publication of IT1251788B publication Critical patent/IT1251788B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invenzione riguarda un procedimento di preparazione di particelle che hanno la funzione di cedere una quantità efficace di ingrediente attivo entro un predeterminato periodo di tempo, dette particelle contenendo uno o più ingredienti attivi in miscela con un polimero oppure con un copolimero bioassorbibile e/o biodegradabile, e riguarda le particelle così ottenute in una forma sostanzialmente sferoidale e sostanzialmente priva di ingrediente attivo sul rivestimento esterno.
ITMI911953A 1990-08-01 1991-07-15 Procedimento di preparazione di composizione a cessione protratta e le composizioni cosi' ottenute IT1251788B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (3)

Publication Number Publication Date
ITMI911953A0 ITMI911953A0 (it) 1991-07-15
ITMI911953A1 ITMI911953A1 (it) 1993-01-15
IT1251788B true IT1251788B (it) 1995-05-26

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911953A IT1251788B (it) 1990-08-01 1991-07-15 Procedimento di preparazione di composizione a cessione protratta e le composizioni cosi' ottenute

Country Status (30)

Country Link
US (1) US5213812A (it)
JP (1) JP2818704B2 (it)
KR (1) KR920003962A (it)
AT (1) AT396425B (it)
AU (2) AU649696B2 (it)
BE (1) BE1004772A3 (it)
CA (1) CA2048270C (it)
CH (1) CH682715A5 (it)
DE (1) DE4125542A1 (it)
DK (1) DK175756B1 (it)
ES (1) ES2046083B1 (it)
FI (1) FI104149B1 (it)
FR (1) FR2665360B1 (it)
GB (1) GB9016885D0 (it)
GR (1) GR1001512B (it)
HK (1) HK33294A (it)
IE (1) IE65124B1 (it)
IN (1) IN178446B (it)
IT (1) IT1251788B (it)
LU (1) LU87982A1 (it)
MA (1) MA22245A1 (it)
MY (1) MY107500A (it)
NL (1) NL194637C (it)
NO (1) NO300158B1 (it)
NZ (1) NZ238981A (it)
OA (1) OA09387A (it)
PT (1) PT98497B (it)
SE (1) SE505734C2 (it)
TN (1) TNSN91067A1 (it)
ZA (1) ZA915565B (it)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5569467A (en) * 1993-05-15 1996-10-29 Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) Process for the preparation of microballs and microballs thus obtained
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
EP0740548B1 (en) * 1994-02-28 2002-12-04 Nanopharm AG Drug targeting system, method for preparing same and its use
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
WO1998015263A2 (en) * 1996-10-09 1998-04-16 Takeda Chemical Industries, Ltd. A method for producing a microparticle
MY118835A (en) * 1997-04-18 2005-01-31 Ipsen Pharma Biotech Sustained release compositions and the process for their preparation
WO1999052708A1 (en) 1998-04-13 1999-10-21 Luminex Corporation Liquid labeling with fluorescent microparticles
EA004502B1 (ru) * 1998-12-16 2004-04-29 Авентис Фармасьютикалз Инк. Фармацевтическая композиция антагониста рецептора серотонина и способ ее получения
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
US7374782B2 (en) 2000-10-27 2008-05-20 Baxter International Inc. Production of microspheres
US20050233945A1 (en) * 2003-07-18 2005-10-20 Larry Brown Methods for fabrication, uses and compositions of small spherical particles of insulin prepared by controlled phase separation
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
DK1418890T3 (da) * 2001-08-16 2008-08-11 Baxter Int Drivmiddel-baserede mikropartikelformuleringer
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20050048127A1 (en) * 2003-07-22 2005-03-03 Larry Brown Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20060135277A1 (en) * 2003-09-10 2006-06-22 Marnocha Bendict F Golf club and practice arrangement
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
PT1765294E (pt) * 2004-05-12 2008-12-30 Baxter Healthcare Sa Microesferas de ácido nucleico, sua produção e entrega
WO2005112885A2 (en) * 2004-05-12 2005-12-01 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
US8333995B2 (en) * 2004-05-12 2012-12-18 Baxter International, Inc. Protein microspheres having injectable properties at high concentrations
CA2573341A1 (en) * 2004-07-13 2006-02-16 Altairnano, Inc. Ceramic structures for prevention of drug diversion
AU2005271782A1 (en) * 2004-07-13 2006-02-16 Altairnano, Inc. Ceramic structures for controlled release of drugs
WO2006050345A1 (en) * 2004-10-29 2006-05-11 Adhesives Research, Inc. Microscopic tagging system for security identification
AU2006241145B2 (en) * 2005-04-27 2011-04-28 Baxter Healthcare S. A. Surface-modified microparticles and methods of forming and using the same
JP2009505824A (ja) * 2005-08-23 2009-02-12 アルテアナノ インコーポレイテッド 高度な光触媒のリンドープアナターゼＴｉＯ２組成物及びその製造方法
US20080020175A1 (en) * 2006-03-02 2008-01-24 Fred Ratel Nanostructured Indium-Doped Iron Oxide
US20080044638A1 (en) * 2006-03-02 2008-02-21 Fred Ratel Nanostructured Metal Oxides
US20080038482A1 (en) * 2006-03-02 2008-02-14 Fred Ratel Method for Low Temperature Production of Nano-Structured Iron Oxide Coatings
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
MX2009001226A (es) * 2006-08-04 2009-03-20 Baxter Int Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio.
MX2009003661A (es) * 2006-10-06 2009-04-22 Baxter Int Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas.
EP2077821B1 (en) 2006-10-12 2019-08-14 The University Of Queensland Compositions and methods for modulating immune responses
US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
US20080254258A1 (en) * 2007-04-12 2008-10-16 Altairnano, Inc. Teflon® replacements and related production methods
AU2008242842B2 (en) * 2007-04-17 2014-06-05 Baxter Healthcare Sa Nucleic acid microparticles for pulmonary delivery
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
ES2554168T3 (es) 2008-04-18 2015-12-16 Baxter International Inc. Composición basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nueva aparición
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US20100078848A1 (en) * 2008-09-29 2010-04-01 Armark Authentication Technologies, Llc Spinneret and method of spinning fiber
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
WO2010132763A1 (en) * 2009-05-15 2010-11-18 Armark Authentication Technologies, Llc Fiber having non-uniform composition and method for making same
CN107252482A (zh) 2009-05-27 2017-10-17 西莱克塔生物科技公司 具有不同释放速率的纳米载体加工组分
EP2480596A1 (en) * 2009-09-25 2012-08-01 Armark Authentication Technologies, LLC Tissue fiber scaffold and method for making
US20110293701A1 (en) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Multivalent synthetic nanocarrier vaccines
EP2399931A1 (fr) * 2010-06-22 2011-12-28 Ipsen Pharma S.A.S. Nouveaux composés octapeptidiques et leur utilisation thérapeutique
BR112013010926A2 (pt) 2010-11-01 2016-08-23 Univ Technology Sidney agentes imunomoduladores e seus usos
CN109172819A (zh) 2011-07-29 2019-01-11 西莱克塔生物科技公司 产生体液和细胞毒性t淋巴细胞（ctl）免疫应答的合成纳米载体
EP3149049B1 (en) 2014-05-27 2022-10-26 The University Of Queensland Il-22 for use in treating metabolic disorders
FR3067226B1 (fr) * 2017-06-13 2021-10-08 Rossignol Lange Element de chaussure de ski

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3567650A (en) * 1969-02-14 1971-03-02 Ncr Co Method of making microscopic capsules
US4010125A (en) * 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
IN167096B (it) * 1985-04-04 1990-09-01 Akzo Nv
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
AU4369589A (en) * 1988-10-27 1990-05-03 Abbott Laboratories Controlled-release delivery device, method for producing device, and method of using device

Also Published As

Publication number Publication date
GB9016885D0 (en) 1990-09-12
ES2046083B1 (es) 1994-08-01
GR1001512B (el) 1994-02-28
DK141891A (da) 1992-02-02
HK33294A (en) 1994-04-22
FI913646A0 (fi) 1991-07-31
CH682715A5 (fr) 1993-11-15
OA09387A (fr) 1992-09-15
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
IE912700A1 (en) 1992-02-12
JP2818704B2 (ja) 1998-10-30
MY107500A (en) 1995-12-30
NO912986D0 (no) 1991-07-31
ATA152591A (de) 1993-01-15
ZA915565B (en) 1992-04-29
SE9102249D0 (sv) 1991-07-26
FI913646A (fi) 1992-02-02
CA2048270C (en) 1997-02-25
NL9101306A (nl) 1992-03-02
AU8146691A (en) 1992-02-06
SE9102249L (sv) 1992-02-02
IN178446B (it) 1997-05-03
BE1004772A3 (fr) 1993-01-26
JPH05178740A (ja) 1993-07-20
CA2048270A1 (en) 1992-02-02
IE65124B1 (en) 1995-10-04
DK141891D0 (da) 1991-07-31
NL194637C (nl) 2002-10-04
ITMI911953A1 (it) 1993-01-15
FI104149B (fi) 1999-11-30
PT98497B (pt) 1997-10-31
DK175756B1 (da) 2005-02-14
PT98497A (pt) 1992-06-30
LU87982A1 (fr) 1992-04-15
FI104149B1 (fi) 1999-11-30
AU5939394A (en) 1994-06-02
NO300158B1 (no) 1997-04-21
NZ238981A (en) 1992-11-25
GR910100330A (en) 1992-08-31
DE4125542A1 (de) 1992-02-06
FR2665360B1 (fr) 1995-02-10
AU666808B2 (en) 1996-02-22
ITMI911953A0 (it) 1991-07-15
US5213812A (en) 1993-05-25
KR920003962A (ko) 1992-03-27
AT396425B (de) 1993-09-27
ES2046083A1 (es) 1994-01-16
TNSN91067A1 (fr) 1992-10-25
SE505734C2 (sv) 1997-10-06
MA22245A1 (fr) 1992-04-01
AU649696B2 (en) 1994-06-02
FR2665360A1 (fr) 1992-02-07

Similar Documents

Publication Publication Date Title
IT1251788B (it) Procedimento di preparazione di composizione a cessione protratta e le composizioni cosi' ottenute
AU8142594A (en) Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
BR9916053A (pt) Composições contendo um peptìdio e um ácido glicólico poliláctico, adequadas para preparação de implantes subcutâneos com perìodo de liberação prolongado
EP0858803A4 (en) COMPOSITION FOR LOCAL ANESTHESIA
DK365389D0 (da) Antifungalt tyggegummipraeparat
MY118699A (en) Binding agent for solid block functional material
MY113981A (en) Pharmaceutical composition containing a diclofenac salt and 2-hydroxypropyl-b-cyclodextrin
CA2215495A1 (en) Environmentally friendly chewing gum compositions containing elastic protein-based polymers
IT1247945B (it) Agente avente attivita' batteriostatica e battericida
CA2015186A1 (en) Nutrient composition
JO1883B1 (en) Enrofloxacin injection or infusion solutions
ATE205074T1 (de) Schminkgarnitur mit filmbildenden zusammensetzungen
DE69327797D1 (de) Zusammensetzungen aus bleichmittelvorläufern enthaltend eine beschichtete peroxysäure
CA2178163A1 (en) Water soluble granular compositions comprising an imidazolinone herbicide and a base
PL345811A1 (en) Pharmaceutical compositions comprising ibuprofen and domperidone
AU560739B2 (en) Detergent composition based on amorphous aluminasilicate
GB1250725A (it)
NO943373D0 (no) Psyliumholdig sammensatt blandingsdrikk
IL96409A0 (en) Biodegradable,water-soluble polycarboxylic acid copolymers,compositions containing them,and their use
YU23498A (sh) Herbicidni 3,5-difluoropiridini
JPS5241244A (en) Sustained release aromatic composition and method of making the same
GB1243565A (en) Rodenticidal compositions
IE38787L (en) Antimicrobial compositions
MY106874A (en) Flowability improving agent, a process for the production thereof and a use thereof.
CA2055045A1 (en) Light-duty dishwashing detergent composition containing an alkyl ethoxy carboxylate surfactant and calcium ions

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970730