ES2046083B1 - Procedimiento para preparar composiciones de liberacion prolongada. - Google Patents

Procedimiento para preparar composiciones de liberacion prolongada.

Info

Publication number
ES2046083B1
ES2046083B1 ES09101785A ES9101785A ES2046083B1 ES 2046083 B1 ES2046083 B1 ES 2046083B1 ES 09101785 A ES09101785 A ES 09101785A ES 9101785 A ES9101785 A ES 9101785A ES 2046083 B1 ES2046083 B1 ES 2046083B1
Authority
ES
Spain
Prior art keywords
procedure
prolonged release
release compositions
preparing
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09101785A
Other languages
English (en)
Spanish (es)
Other versions
ES2046083A1 (es
Inventor
Jean-Marc Ruiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES2046083A1 publication Critical patent/ES2046083A1/es
Application granted granted Critical
Publication of ES2046083B1 publication Critical patent/ES2046083B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Glanulating (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
ES09101785A 1990-08-01 1991-07-30 Procedimiento para preparar composiciones de liberacion prolongada. Expired - Fee Related ES2046083B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ES2046083A1 ES2046083A1 (es) 1994-01-16
ES2046083B1 true ES2046083B1 (es) 1994-08-01

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09101785A Expired - Fee Related ES2046083B1 (es) 1990-08-01 1991-07-30 Procedimiento para preparar composiciones de liberacion prolongada.

Country Status (30)

Country Link
US (1) US5213812A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2818704B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR920003962A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT396425B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU649696B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE1004772A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2048270C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH682715A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE4125542A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK175756B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2046083B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI104149B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2665360B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB9016885D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR1001512B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK33294A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE65124B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN178446B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1251788B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU87982A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (1) MA22245A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY107500A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL194637C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO300158B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ238981A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA09387A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT98497B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE505734C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TN (1) TNSN91067A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA915565B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
US5569467A (en) * 1993-05-15 1996-10-29 Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) Process for the preparation of microballs and microballs thus obtained
HUT75469A (en) * 1994-02-28 1997-05-28 Medinova Med Consulting Gmbh Drug targeting system, method for preparing same and its use
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
AU4571097A (en) * 1996-10-09 1998-05-05 Takeda Chemical Industries Ltd. A method for producing a microparticle
TW577759B (en) * 1997-04-18 2004-03-01 Ipsen Pharma Biotech Sustained release compositions in the form of microcapsules or implants and the process for their preparation
WO1999052708A1 (en) 1998-04-13 1999-10-21 Luminex Corporation Liquid labeling with fluorescent microparticles
EA004502B1 (ru) * 1998-12-16 2004-04-29 Авентис Фармасьютикалз Инк. Фармацевтическая композиция антагониста рецептора серотонина и способ ее получения
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
EP1335661B1 (en) 2000-10-27 2009-05-06 Baxter Healthcare S.A. Production of microspheres
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
ATE395042T1 (de) * 2001-08-16 2008-05-15 Baxter Int Darreichungsformen welche mikropartikel und treibgas enthalten
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
KR101137785B1 (ko) * 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
US20050048127A1 (en) * 2003-07-22 2005-03-03 Larry Brown Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20060135277A1 (en) * 2003-09-10 2006-06-22 Marnocha Bendict F Golf club and practice arrangement
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
ES2313350T3 (es) * 2004-05-12 2009-03-01 Baxter International Inc. Microesferas de acido nucleico, produccion y suministro de las mismas.
CA2566075A1 (en) * 2004-05-12 2005-12-01 Baxter Healthcare S.A. Microspheres comprising protein and showing injectability at high concentrations of said agent
WO2005112885A2 (en) * 2004-05-12 2005-12-01 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
CN101001610A (zh) * 2004-07-13 2007-07-18 爱尔达纳米公司 防止药物转向的陶瓷结构
CA2573344A1 (en) * 2004-07-13 2006-02-16 Altairnano, Inc. Ceramic structures for controlled release of drugs
WO2006050345A1 (en) * 2004-10-29 2006-05-11 Adhesives Research, Inc. Microscopic tagging system for security identification
WO2006116546A1 (en) * 2005-04-27 2006-11-02 Baxter International Inc. Surface-modified microparticles and methods of forming and using the same
CA2620167A1 (en) * 2005-08-23 2007-03-01 Altairnano, Inc. Highly photocatalytic phosphorus-doped anatase-tio2 composition and related manufacturing methods
WO2007103820A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Nanostructured indium-doped iron oxide
WO2007103824A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Nanostructured metal oxides
WO2007103812A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Method for low temperature production of nano-structured iron oxide coatings
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
EP2647712A3 (en) 2006-08-04 2013-11-20 Baxter International Inc Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
WO2008060786A2 (en) * 2006-10-06 2008-05-22 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
EP2077821B1 (en) 2006-10-12 2019-08-14 The University Of Queensland Compositions and methods for modulating immune responses
US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
WO2008128000A1 (en) * 2007-04-12 2008-10-23 Altairnano, Inc. Teflon replacements and related production methods
WO2008131129A2 (en) * 2007-04-17 2008-10-30 Baxter International Inc. Nucleic acid microparticles for pulmonary delivery
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
JP5685182B2 (ja) 2008-04-18 2015-03-18 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 初発自己免疫性糖尿病を予防するため、および／または逆転させるためのマイクロスフェアに基づく組成物
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
WO2010037021A2 (en) * 2008-09-29 2010-04-01 Armark Authentication Technologies, Llc Spinneret and method of spinning fiber
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
WO2010132763A1 (en) * 2009-05-15 2010-11-18 Armark Authentication Technologies, Llc Fiber having non-uniform composition and method for making same
MX2011012598A (es) 2009-05-27 2012-04-19 Selecta Biosciences Inc Nanoportadores sinteticos objetivos con liberacion sensible al ph de agentes inmunomoduladores.
WO2011038053A1 (en) * 2009-09-25 2011-03-31 Armark Authentication Technologies, Llc Tissue fiber scaffold and method for making
MX2012013715A (es) 2010-05-26 2013-01-28 Selecta Biosciences Inc Seleccion de dosis de nanovehiculos sinteticos con adyuvante.
EP2399931A1 (fr) * 2010-06-22 2011-12-28 Ipsen Pharma S.A.S. Nouveaux composés octapeptidiques et leur utilisation thérapeutique
WO2012058715A1 (en) 2010-11-01 2012-05-10 University Of Technology, Sydney Immune-modulating agents and uses therefor
CA2843274A1 (en) 2011-07-29 2013-02-07 Selecta Biosciences, Inc. Synthetic nanocarriers that generate humoral and cytotoxic t lymphocyte (ctl) immune responses
WO2015179918A1 (en) 2014-05-27 2015-12-03 The University Of Queensland Modulation of cellular stress
FR3067226B1 (fr) * 2017-06-13 2021-10-08 Rossignol Lange Element de chaussure de ski

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3567650A (en) * 1969-02-14 1971-03-02 Ncr Co Method of making microscopic capsules
US4010125A (en) * 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
IN167096B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1985-04-04 1990-09-01 Akzo Nv
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
AU4369589A (en) * 1988-10-27 1990-05-03 Abbott Laboratories Controlled-release delivery device, method for producing device, and method of using device

Also Published As

Publication number Publication date
MA22245A1 (fr) 1992-04-01
SE9102249L (sv) 1992-02-02
SE505734C2 (sv) 1997-10-06
FR2665360A1 (fr) 1992-02-07
PT98497B (pt) 1997-10-31
IN178446B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-05-03
FR2665360B1 (fr) 1995-02-10
IE912700A1 (en) 1992-02-12
HK33294A (en) 1994-04-22
NO912986D0 (no) 1991-07-31
KR920003962A (ko) 1992-03-27
NO300158B1 (no) 1997-04-21
GB9016885D0 (en) 1990-09-12
FI104149B (fi) 1999-11-30
PT98497A (pt) 1992-06-30
AT396425B (de) 1993-09-27
JP2818704B2 (ja) 1998-10-30
GR910100330A (en) 1992-08-31
NL9101306A (nl) 1992-03-02
ZA915565B (en) 1992-04-29
CA2048270A1 (en) 1992-02-02
NZ238981A (en) 1992-11-25
MY107500A (en) 1995-12-30
ITMI911953A0 (it) 1991-07-15
US5213812A (en) 1993-05-25
AU666808B2 (en) 1996-02-22
NL194637C (nl) 2002-10-04
GR1001512B (el) 1994-02-28
DK141891A (da) 1992-02-02
SE9102249D0 (sv) 1991-07-26
TNSN91067A1 (fr) 1992-10-25
FI913646A0 (fi) 1991-07-31
AU8146691A (en) 1992-02-06
LU87982A1 (fr) 1992-04-15
ES2046083A1 (es) 1994-01-16
CA2048270C (en) 1997-02-25
BE1004772A3 (fr) 1993-01-26
DE4125542A1 (de) 1992-02-06
DK141891D0 (da) 1991-07-31
ATA152591A (de) 1993-01-15
AU5939394A (en) 1994-06-02
AU649696B2 (en) 1994-06-02
IT1251788B (it) 1995-05-26
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
JPH05178740A (ja) 1993-07-20
IE65124B1 (en) 1995-10-04
ITMI911953A1 (it) 1993-01-15
FI104149B1 (fi) 1999-11-30
OA09387A (fr) 1992-09-15
FI913646L (fi) 1992-02-02
DK175756B1 (da) 2005-02-14
CH682715A5 (fr) 1993-11-15

Similar Documents

Publication Publication Date Title
ES2046083B1 (es) Procedimiento para preparar composiciones de liberacion prolongada.
HRP20010463B1 (hr) Smjesa s kontroliranim otpuštanjem koja sadrži galantamin
AU7315301A (en) Compounds and compositions for delivering active agents
ES2031096T3 (es) Una composicion de implante mejorada a base de estradiol y metodo para su preparacion.
SE9003665D0 (sv) Morphine prodrugs
IL115721A0 (en) Methods and compositions for the modulation of cell proliferation and wound healing
MXPA01008611A (es) Compuestos y composiciones para suministrar agentes activos.
BR0009893A (pt) Composição de cuidado com a pele; e uso de uma composição de cuidado com a pele
DK0589893T3 (da) Anvendelse af et bakteriocin som antimikrobielt middel til fremstilling af et lægemiddel til behandl ing af maveforstyrrelser forbundet med helicobacter pylori
MX9705710A (es) Compuestos con propiedades de liberacion de la hormona del crecimiento.
ATE286725T1 (de) Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe
DE60129849D1 (de) Bioadhäsiver schaumstoffilm mit hinhaltender wirkstoffreigabe
ATE324907T1 (de) Verbindung und arzneizusammensetzung zur verabreichung von wirkstoffen
BG66093B1 (bg) Състави с контролирано освобождаване, съдържащи нимесулид
HUP9702457A3 (en) Synergistic herbicidal compositions containing glufosinate and nitrodiphenyl ether derivatives as active ingredients and use thereof
DE60040753D1 (de) Therapeutische verwendungen von steroiden bei blutzellmangelzustaenden
DK0975334T3 (da) Biologisk nedbrydelige mikropartikler til langvarig frigivelse af terapeutiske midler
HUT52083A (en) Herbicidal compositions comprising cyclohexenone oxymetres as active ingredient and process for producing the active ingredients
IT1302682B1 (it) Composizioni farmaceutiche orali contenenti buprenorfina
WO2002015959A3 (en) Compounds and compositions for delivering active agents
AU8916198A (en) Composition, device and method of using
ATE281830T1 (de) Geschmacksneutrale pharmazeutische zusammensetzungen
DE69727385D1 (de) Benzophenanthridinalkaloid-enthaltende pestizide
NO941097D0 (no) Hudregenererende kosmetisk preparat
DK0469440T3 (da) Faste orale applikationsformer, der som aktivt stof indeholder ifosamid

Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20110819