AT394947B - Verfahren zur herstellung einer fluessigen nasal verabreichbaren calcitoninzusammensetzung - Google Patents
Verfahren zur herstellung einer fluessigen nasal verabreichbaren calcitoninzusammensetzung Download PDFInfo
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- AT394947B AT394947B AT0349483A AT349483A AT394947B AT 394947 B AT394947 B AT 394947B AT 0349483 A AT0349483 A AT 0349483A AT 349483 A AT349483 A AT 349483A AT 394947 B AT394947 B AT 394947B
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- Prior art keywords
- calcitonin
- nasal
- composition
- administration
- compositions
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- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT259288A AT402895B (de) | 1982-10-05 | 1988-10-20 | Verfahren zur herstellung einer flüssigen pharmazeutischenzusammensetzung für die nasale verabreichung eines calcitonins als nasaler spray |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8228390 | 1982-10-05 | ||
| GB8236928 | 1982-12-30 | ||
| GB838320865A GB8320865D0 (en) | 1983-08-03 | 1983-08-03 | Organic compounds |
| GB838322528A GB8322528D0 (en) | 1983-08-22 | 1983-08-22 | Organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA349483A ATA349483A (de) | 1992-01-15 |
| AT394947B true AT394947B (de) | 1992-07-27 |
Family
ID=27449393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0349483A AT394947B (de) | 1982-10-05 | 1983-10-03 | Verfahren zur herstellung einer fluessigen nasal verabreichbaren calcitoninzusammensetzung |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5759565A (en, 2012) |
| JP (1) | JPH07103043B2 (en, 2012) |
| AT (1) | AT394947B (en, 2012) |
| AU (2) | AU572800B2 (en, 2012) |
| CA (1) | CA1220138A (en, 2012) |
| CH (1) | CH657779A5 (en, 2012) |
| DE (1) | DE3335086A1 (en, 2012) |
| DK (1) | DK161800C (en, 2012) |
| FR (1) | FR2533826B1 (en, 2012) |
| HK (1) | HK27389A (en, 2012) |
| HU (1) | HU192246B (en, 2012) |
| IL (1) | IL69892A (en, 2012) |
| IT (1) | IT1172324B (en, 2012) |
| KE (1) | KE3848A (en, 2012) |
| MY (1) | MY8700271A (en, 2012) |
| NL (1) | NL192563C (en, 2012) |
| NZ (1) | NZ205846A (en, 2012) |
| PH (1) | PH22725A (en, 2012) |
| PT (1) | PT77443B (en, 2012) |
| SE (1) | SE455671B (en, 2012) |
| SG (1) | SG76388G (en, 2012) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL70489A0 (en) * | 1982-12-29 | 1984-03-30 | Armour Pharma | Pharmaceutical compositions containing calcitonin |
| IT1250691B (it) * | 1991-07-22 | 1995-04-21 | Giancarlo Santus | Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac. |
| US5571788A (en) * | 1991-12-09 | 1996-11-05 | Ciba-Geigy Corporation | Stable calcitonin pharmaceutical compositions |
| US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
| DE726075T1 (de) * | 1995-02-08 | 1996-12-12 | Therapicon Srl | Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung |
| US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| TWI243687B (en) * | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
| US6056976A (en) * | 1998-11-12 | 2000-05-02 | Leiras Oy | Elastomer, its preparation and use |
| US6063395A (en) * | 1998-11-12 | 2000-05-16 | Leiras Oy | Drug delivery device especially for the delivery of progestins and estrogens |
| AR026073A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
| EP1251867A4 (en) | 2000-02-04 | 2004-12-08 | Unigene Lab Inc | NASAL CALCITON INFORMATION |
| US6531112B2 (en) * | 2000-05-15 | 2003-03-11 | Delrx Pharmaceutical Corporation | Formulations for administering calcitonin and processes for preparing the same |
| US20090035260A1 (en) * | 2002-07-29 | 2009-02-05 | Therapicon Srl | Enhanced nasal composition of active peptide |
| US7166575B2 (en) * | 2002-12-17 | 2007-01-23 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity |
| US7229966B2 (en) * | 2002-12-17 | 2007-06-12 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity |
| US7186692B2 (en) * | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
| EP1581245A2 (en) * | 2002-12-17 | 2005-10-05 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of y2 receptor-binding peptides and methods for treating and preventing obesity |
| US7812120B2 (en) | 2003-03-21 | 2010-10-12 | Par Pharmaceutical, Inc. | Nasal calcitonin formulations containing chlorobutanol |
| US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| DE502004002585D1 (de) * | 2003-10-15 | 2007-02-15 | Pari Gmbh | Flüssige zubereitung enthaltend tobramycin |
| ITMI20040235A1 (it) * | 2004-02-13 | 2004-05-13 | Therapicon Srl | Preparazione farmaceutica per il cavo orale |
| US20100256060A1 (en) * | 2009-04-02 | 2010-10-07 | Unigene Laboratories Inc. | Peptide pharmaceuticals for nasal delivery |
| ES2641325T3 (es) | 2012-01-26 | 2017-11-08 | Christopher J. Soares | Antagonistas peptídicos de la familia calcitonina CGRP de hormonas peptídicas y su uso |
| AU2017319512A1 (en) | 2016-09-02 | 2019-03-21 | Christopher J. Soares | Use of CGRP receptor antagonists in neuroprotection and neurological disorders |
| US10723716B2 (en) | 2016-12-21 | 2020-07-28 | New York University | Alpha-helix mimetics as modulators of Abeta self-assembly |
| US11124479B2 (en) | 2017-07-14 | 2021-09-21 | New York University | Oligopyrroles as antagonists of islet amyloid polypeptide oligomerization |
| US10500197B2 (en) | 2017-07-18 | 2019-12-10 | New York University | Use of oligopyridylamides to inhibit mutant p53 amyloid formation and restore its tumor suppressor function |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2118626A1 (de) * | 1970-04-17 | 1971-10-28 | Armour Pharmaceutical Co., Chicago, 111. (V.St.A.) | Pharmazeutische Präparate mit diuretischer Wirkung in bezug auf Natrium und Wasser |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH539556A (de) * | 1971-03-16 | 1973-07-31 | Ciba Geigy Ag | Applikator zur dosierten Ausgabe einer Flüssigkeit |
| GB1354526A (en) * | 1971-04-19 | 1974-06-05 | Armour Pharma | Preparation for obtaining diuresis in animals |
| GB1527605A (en) * | 1975-08-20 | 1978-10-04 | Takeda Chemical Industries Ltd | Insulin preparation for intranasal administration |
| GB2008403B (en) * | 1977-11-04 | 1982-07-28 | Christie R B Parsons J A | Pharmaceutical compositions |
| US4241051A (en) * | 1977-11-04 | 1980-12-23 | Christie Robert B | Calcitonin |
| DE2903957A1 (de) * | 1979-02-02 | 1980-08-07 | Boehringer Sohn Ingelheim | Mittel zur behandlung der nasalen hypersekretion |
| JPS5625197A (en) * | 1979-07-19 | 1981-03-10 | Microbial Chem Res Found | Cleomycin and its preparation |
| JPS56100714A (en) * | 1980-01-16 | 1981-08-12 | Teijin Ltd | Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane |
| JPS56122309A (en) * | 1980-03-03 | 1981-09-25 | Teijin Ltd | Calcitonin pharmaceutical for rectal administration |
| EP0053754B1 (de) * | 1980-12-06 | 1986-04-23 | Reichert, Dietrich, Dr. med. | Mittel zur Bekämpfung des Schnarchens und Verfahren zu dessen Anwendung |
| IL70489A0 (en) * | 1982-12-29 | 1984-03-30 | Armour Pharma | Pharmaceutical compositions containing calcitonin |
| GB8514090D0 (en) * | 1985-06-04 | 1985-07-10 | Sandoz Ltd | Organic compounds |
| IT1222734B (it) * | 1987-09-25 | 1990-09-12 | Scalvo S P A | Formulaziopne farmaceutiche e forme di dosaggio per la somminaistarzione rettale di calcitonina |
-
1983
- 1983-09-27 CH CH5226/83A patent/CH657779A5/de not_active IP Right Cessation
- 1983-09-28 DE DE19833335086 patent/DE3335086A1/de active Granted
- 1983-10-03 PT PT77443A patent/PT77443B/pt unknown
- 1983-10-03 NZ NZ205846A patent/NZ205846A/en unknown
- 1983-10-03 AT AT0349483A patent/AT394947B/de not_active IP Right Cessation
- 1983-10-03 NL NL8303386A patent/NL192563C/nl not_active IP Right Cessation
- 1983-10-03 IL IL69892A patent/IL69892A/xx not_active IP Right Cessation
- 1983-10-03 FR FR8315837A patent/FR2533826B1/fr not_active Expired
- 1983-10-03 AU AU19849/83A patent/AU572800B2/en not_active Expired
- 1983-10-04 PH PH29651A patent/PH22725A/en unknown
- 1983-10-04 HU HU833443A patent/HU192246B/hu unknown
- 1983-10-04 DK DK458183A patent/DK161800C/da not_active IP Right Cessation
- 1983-10-05 SE SE8305485A patent/SE455671B/sv not_active IP Right Cessation
- 1983-10-05 CA CA000438434A patent/CA1220138A/en not_active Expired
- 1983-10-05 IT IT49105/83A patent/IT1172324B/it active Protection Beyond IP Right Term
-
1987
- 1987-12-30 MY MY271/87A patent/MY8700271A/xx unknown
-
1988
- 1988-08-17 AU AU21035/88A patent/AU2103588A/en not_active Abandoned
- 1988-11-15 SG SG763/88A patent/SG76388G/en unknown
- 1988-11-25 KE KE3848A patent/KE3848A/xx unknown
-
1989
- 1989-03-30 HK HK273/89A patent/HK27389A/xx not_active IP Right Cessation
-
1990
- 1990-03-12 JP JP2060862A patent/JPH07103043B2/ja not_active Expired - Lifetime
-
1991
- 1991-12-31 US US07/815,457 patent/US5759565A/en not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/471,118 patent/US5733569A/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2118626A1 (de) * | 1970-04-17 | 1971-10-28 | Armour Pharmaceutical Co., Chicago, 111. (V.St.A.) | Pharmazeutische Präparate mit diuretischer Wirkung in bezug auf Natrium und Wasser |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| ELA | Expired due to lapse of time |