AT391323B - Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure - Google Patents
Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure Download PDFInfo
- Publication number
- AT391323B AT391323B AT0055589A AT55589A AT391323B AT 391323 B AT391323 B AT 391323B AT 0055589 A AT0055589 A AT 0055589A AT 55589 A AT55589 A AT 55589A AT 391323 B AT391323 B AT 391323B
- Authority
- AT
- Austria
- Prior art keywords
- lactic acid
- microorganism
- medium
- cultivation
- carried out
- Prior art date
Links
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 title claims description 33
- 238000000034 method Methods 0.000 title claims description 25
- 244000005700 microbiome Species 0.000 title claims description 23
- 238000004519 manufacturing process Methods 0.000 title claims description 9
- 241000193749 Bacillus coagulans Species 0.000 title claims description 5
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 18
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 11
- 239000008103 glucose Substances 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 9
- 235000014655 lactic acid Nutrition 0.000 claims description 9
- 239000004310 lactic acid Substances 0.000 claims description 9
- 239000005720 sucrose Substances 0.000 claims description 9
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 8
- 229910052757 nitrogen Inorganic materials 0.000 claims description 8
- 150000001720 carbohydrates Chemical class 0.000 claims description 7
- 235000014633 carbohydrates Nutrition 0.000 claims description 7
- 240000008042 Zea mays Species 0.000 claims description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 5
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 5
- 235000005822 corn Nutrition 0.000 claims description 5
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 3
- 239000004254 Ammonium phosphate Substances 0.000 claims description 2
- 229910000148 ammonium phosphate Inorganic materials 0.000 claims description 2
- 235000019289 ammonium phosphates Nutrition 0.000 claims description 2
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 claims description 2
- 238000011534 incubation Methods 0.000 claims description 2
- 238000011081 inoculation Methods 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 235000008733 Citrus aurantifolia Nutrition 0.000 claims 1
- JVTAAEKCZFNVCJ-UWTATZPHSA-N D-lactic acid Chemical compound C[C@@H](O)C(O)=O JVTAAEKCZFNVCJ-UWTATZPHSA-N 0.000 claims 1
- 235000011941 Tilia x europaea Nutrition 0.000 claims 1
- 239000004571 lime Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 125000001477 organic nitrogen group Chemical group 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 125000000185 sucrose group Chemical group 0.000 claims 1
- 239000002609 medium Substances 0.000 description 11
- 230000015572 biosynthetic process Effects 0.000 description 5
- 235000015097 nutrients Nutrition 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 229940041514 candida albicans extract Drugs 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 239000012138 yeast extract Substances 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 229940054340 bacillus coagulans Drugs 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241001112741 Bacillaceae Species 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- SRBFZHDQGSBBOR-HWQSCIPKSA-N L-arabinopyranose Chemical compound O[C@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-HWQSCIPKSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 241001468155 Lactobacillaceae Species 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 229920000704 biodegradable plastic Polymers 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 230000009615 deamination Effects 0.000 description 1
- 238000006481 deamination reaction Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000003630 growth substance Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 150000003018 phosphorus compounds Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000004460 silage Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0055589A AT391323B (de) | 1989-03-10 | 1989-03-10 | Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure |
| DE4000942A DE4000942A1 (de) | 1989-03-10 | 1990-01-15 | Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure |
| US07/485,451 US5079164A (en) | 1989-03-10 | 1990-02-27 | Microorganism of the species bacillus ciaguans |
| FR9002947A FR2644178B1 (fr) | 1989-03-10 | 1990-03-08 | Micro-organisme de l'espece bacillus coagulans et procede utilisant ce micro-organisme pour produire de l'acide l(+)lactique optiquement pur |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0055589A AT391323B (de) | 1989-03-10 | 1989-03-10 | Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA55589A ATA55589A (de) | 1990-03-15 |
| AT391323B true AT391323B (de) | 1990-09-25 |
Family
ID=3493711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0055589A AT391323B (de) | 1989-03-10 | 1989-03-10 | Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5079164A (en:Method) |
| AT (1) | AT391323B (en:Method) |
| DE (1) | DE4000942A1 (en:Method) |
| FR (1) | FR2644178B1 (en:Method) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5426219A (en) * | 1993-07-26 | 1995-06-20 | A.E. Staley Manufacturing Co. | Process for recovering organic acids |
| BR9605262A (pt) * | 1995-10-27 | 1998-07-21 | Shimadzu Corp | Método para a produçao de ácido lático com alta pureza óptica usando cepas de bacillus |
| US5766439A (en) * | 1996-10-10 | 1998-06-16 | A. E. Staley Manufacturing Co. | Production and recovery of organic acids |
| US6716435B1 (en) * | 1997-04-18 | 2004-04-06 | Ganeden Biotech, Inc. | Absorbent product containing absorbent structure and Bacillus coagulans |
| WO1998047374A1 (en) * | 1997-04-18 | 1998-10-29 | Ganeden Biotech, Inc. | Topical use of probiotic bacillus spores to prevent or control microbial infections |
| US6645506B1 (en) * | 1997-04-18 | 2003-11-11 | Ganeden Biotech, Inc. | Topical compositions containing extracellular products of Pseudomonas lindbergii and Emu oil |
| US6811786B1 (en) * | 1999-04-01 | 2004-11-02 | Ganeden Biotech, Inc. | Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions |
| EP1719518A1 (en) | 1998-08-07 | 2006-11-08 | Ganeden Biotech, Inc. | Compositions comprising bacillus coagulans for increasing the solubility and bioavailability of nutritional minerals |
| US7767203B2 (en) | 1998-08-07 | 2010-08-03 | Ganeden Biotech, Inc. | Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption |
| US6461607B1 (en) | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| WO2001013956A2 (en) * | 1999-08-26 | 2001-03-01 | Ganeden Biotech, Inc. | Use of emu oil a carrier for antifungal, antibacterial, and antiviral medications |
| US6849256B1 (en) * | 1999-11-08 | 2005-02-01 | Ganeden Biotech Incorporated | Inhibition of pathogens by probiotic bacteria |
| US6509179B1 (en) | 2000-10-12 | 2003-01-21 | Barbara I. Veldhuis-Stribos | Continuous process for preparing lactic acid |
| EE04529B1 (et) * | 2001-03-16 | 2005-08-15 | Tartu �likool | Termofiilne mikroorganismi tüvi Bacillus coagulans SIM-7 DSM 14043 ja meetod L(+)-laktaadi tootmiseks fermenteeritavatest suhkrutest ja nende segudest nimetatud mikroorganismi tüve abil |
| GB0117551D0 (en) * | 2001-07-18 | 2001-09-12 | Elsworth Biotech Ltd | Lastic acid production |
| US6730790B2 (en) * | 2002-03-01 | 2004-05-04 | R.T. Alamo Ventures I. Llc | Chlorinated heterocyclic compounds and methods of synthesis |
| US8119376B2 (en) | 2002-05-14 | 2012-02-21 | Purac Biochem B.V. | Method for the production of lactic acid or a salt thereof by simultaneous saccharification and fermentation of starch |
| US20070065540A1 (en) * | 2003-07-24 | 2007-03-22 | Jones Alison M | Enhanced steep-water |
| US7098009B2 (en) * | 2004-03-04 | 2006-08-29 | University Of Florida Research Foundation, Inc. | Production of chemicals from lignocellulose, biomass or sugars |
| DE102006039203B4 (de) | 2006-08-22 | 2014-06-18 | Evonik Degussa Gmbh | Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu |
| WO2009032121A1 (en) * | 2007-08-29 | 2009-03-12 | Ganeden Biotech, Inc. | Compositions and methods for enhancing paper product degradation |
| DK2211626T3 (da) | 2007-08-29 | 2019-10-21 | Ganeden Biotech Inc | Bagværk |
| DK2638807T3 (da) | 2007-10-16 | 2021-05-25 | Ganeden Biotech Inc | Drikkevaresammensætninger |
| WO2009099562A2 (en) * | 2008-01-30 | 2009-08-13 | Ganeden Biotech, Inc. | Compositions and methods for cleaning surfaces |
| ES2595733T3 (es) * | 2008-10-16 | 2017-01-03 | Ganeden Biotech, Inc. | Composiciones probióticas a base de cereales |
| WO2010103548A2 (en) * | 2009-03-13 | 2010-09-16 | Godavari Biorefineries Ltd. | Improved method for producing lactic acid and derivative thereof |
| WO2010127132A1 (en) | 2009-04-29 | 2010-11-04 | Ganeden Biotech, Inc. | Inactivated bacterial cell formulation |
| US9301982B2 (en) | 2010-04-14 | 2016-04-05 | Ganeden Biotech, Inc. | Probiotic confection and lipid compositions |
| CN101914465B (zh) | 2010-05-20 | 2012-10-03 | 上海交通大学 | 用于制备l-乳酸的凝结芽孢杆菌及其应用方法 |
| WO2012135499A1 (en) | 2011-03-31 | 2012-10-04 | Ganeden Biotech, Inc. | Probiotic sports nutrition compositions |
| JP5892580B2 (ja) * | 2011-04-14 | 2016-03-23 | 国立大学法人 琉球大学 | 新規乳酸菌及びｌ−乳酸の製造方法及び乳酸菌を含む食品および薬品 |
| CN104302278B (zh) | 2012-03-29 | 2018-08-21 | 塞拉拜姆有限责任公司 | 在回肠和阑尾上有活性的胃肠位点特异性口服接种疫苗制剂 |
| CN105120847B (zh) | 2013-03-14 | 2018-12-28 | 塞拉拜姆有限责任公司 | 益生生物和/或治疗剂的靶向胃肠道递送 |
| DE102017101220B4 (de) | 2017-01-23 | 2019-03-21 | Thyssenkrupp Ag | Minimalmedium zur fermentativen Umsetzung von Mono- und/oder Disacchariden zu Milchsäure mit Bacillus coagulans-Stämmen |
| US20240277786A1 (en) | 2023-02-16 | 2024-08-22 | Codex Labs Corporation | Dietary supplement composition for treating and managing acne |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE30965E (en) * | 1978-08-31 | 1982-06-08 | Provesta Corporation | Fermentation of oxygenated hydrocarbon compounds with thermophilic microorganisms and microorganisms therefor |
| JPS606200B2 (ja) * | 1981-08-29 | 1985-02-16 | 大樹 中山 | 有胞子細菌による右旋性乳酸の製造方法 |
-
1989
- 1989-03-10 AT AT0055589A patent/AT391323B/de not_active IP Right Cessation
-
1990
- 1990-01-15 DE DE4000942A patent/DE4000942A1/de active Granted
- 1990-02-27 US US07/485,451 patent/US5079164A/en not_active Expired - Lifetime
- 1990-03-08 FR FR9002947A patent/FR2644178B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE4000942A1 (de) | 1990-09-13 |
| US5079164A (en) | 1992-01-07 |
| ATA55589A (de) | 1990-03-15 |
| DE4000942C2 (en:Method) | 1992-01-16 |
| FR2644178B1 (fr) | 1993-02-19 |
| FR2644178A1 (fr) | 1990-09-14 |
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