AT380256B - Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats - Google Patents
Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivatsInfo
- Publication number
- AT380256B AT380256B AT0319182A AT319182A AT380256B AT 380256 B AT380256 B AT 380256B AT 0319182 A AT0319182 A AT 0319182A AT 319182 A AT319182 A AT 319182A AT 380256 B AT380256 B AT 380256B
- Authority
- AT
- Austria
- Prior art keywords
- oner
- tetrazine
- imidazo
- derivative
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8125791 | 1981-08-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA319182A ATA319182A (de) | 1985-09-15 |
| AT380256B true AT380256B (de) | 1986-05-12 |
Family
ID=10524141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0319182A AT380256B (de) | 1981-08-24 | 1982-08-23 | Verfahren zur herstellung eines neuen (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-onderivats |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS5843975A (pm) |
| KR (1) | KR890000094B1 (pm) |
| AT (1) | AT380256B (pm) |
| AU (1) | AU571430B2 (pm) |
| BE (1) | BE894175A (pm) |
| CA (1) | CA1197247A (pm) |
| CH (1) | CH655114A5 (pm) |
| DE (2) | DE3231255A1 (pm) |
| DK (1) | DK161147C (pm) |
| ES (1) | ES515176A0 (pm) |
| FI (1) | FI73434C (pm) |
| FR (1) | FR2511679A1 (pm) |
| GB (1) | GB2104522B (pm) |
| GE (1) | GEP19960641B (pm) |
| GR (1) | GR76863B (pm) |
| HU (1) | HU186107B (pm) |
| IE (1) | IE53408B1 (pm) |
| IL (1) | IL66606A (pm) |
| IT (1) | IT1152505B (pm) |
| LT (1) | LT2436B (pm) |
| LU (1) | LU84347A1 (pm) |
| LV (2) | LV5511A3 (pm) |
| NL (2) | NL192739C (pm) |
| NZ (1) | NZ201668A (pm) |
| OA (1) | OA07174A (pm) |
| SE (1) | SE448543B (pm) |
| SU (1) | SU1447284A3 (pm) |
| UA (1) | UA5971A1 (pm) |
| ZA (1) | ZA826120B (pm) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR78688B (pm) * | 1982-08-17 | 1984-09-27 | May & Baker Ltd | |
| GB2125402B (en) * | 1982-08-17 | 1985-11-13 | May & Baker Ltd | New tetrazine derivatives |
| US4517182A (en) * | 1983-05-24 | 1985-05-14 | Warner-Lambert Company | 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition |
| GB8616125D0 (en) * | 1986-07-02 | 1986-08-06 | May & Baker Ltd | Compositions of matter |
| AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
| CN100366253C (zh) * | 1995-09-25 | 2008-02-06 | 赛诺菲-安万特美国有限责任公司 | 1,2,4-苯并三嗪氧化物制剂 |
| EP1706407A2 (en) * | 2003-12-30 | 2006-10-04 | Chemagis Ltd. | Novel crystalline forms of temozolomide |
| KR101346886B1 (ko) | 2005-01-21 | 2014-01-02 | 아스텍스 테라퓨틱스 리미티드 | 제약 화합물 |
| PE20080695A1 (es) | 2006-04-27 | 2008-06-28 | Banyu Pharma Co Ltd | Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel |
| JP2008081492A (ja) | 2006-08-31 | 2008-04-10 | Banyu Pharmaceut Co Ltd | オーロラa選択的阻害作用を有する新規アミノピリジン誘導体 |
| US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
| WO2008044045A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
| EP2213673B1 (en) | 2007-10-23 | 2013-06-05 | Msd K.K. | Pyridone-substituted-dihydropyrazolopyrimidinone derivative |
| PE20091101A1 (es) * | 2007-12-18 | 2009-07-26 | Pharminox Ltd | AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO |
| JP2012509868A (ja) * | 2008-11-24 | 2012-04-26 | リライアンス ライフ サイエンシズ ピーヴィーティー リミティッド | テトラジン誘導体の製造方法 |
| US8481503B2 (en) | 2009-03-06 | 2013-07-09 | Merck Sharp & Dohme Corp. | Combination cancer therapy with an AKT inhibitor and other anticancer agents |
| CN102803264A (zh) | 2009-06-23 | 2012-11-28 | 法米诺克斯有限公司 | 3-取代的-8-取代的-3h-咪唑并[5,1-d][1,2,3,5-四嗪-4-酮化合物及其用途 |
| RU2462466C1 (ru) * | 2011-06-24 | 2012-09-27 | Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" | Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ |
| EP2766041B1 (en) | 2011-10-12 | 2018-12-05 | Children's Medical Center Corporation | Combinatorial compositions and methods of treating hemoglobinopathies |
| JP7158023B2 (ja) | 2016-03-15 | 2022-10-21 | オリソン ヘノミクス エセ. アー. | 固形腫瘍の治療における使用のための、lsd1阻害剤の組合せ |
| KR101847342B1 (ko) * | 2017-05-08 | 2018-04-11 | (주)센텍코리아 | 웨어러블 체지방 연소량 측정기 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2932305A1 (de) * | 1979-08-09 | 1981-02-26 | Basf Ag | Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen |
-
1982
- 1982-08-05 OA OA57766BISD patent/OA07174A/xx unknown
- 1982-08-12 IL IL66606A patent/IL66606A/xx not_active IP Right Cessation
- 1982-08-23 NL NL8203286A patent/NL192739C/nl not_active IP Right Cessation
- 1982-08-23 AT AT0319182A patent/AT380256B/de not_active IP Right Cessation
- 1982-08-23 BE BE0/208860A patent/BE894175A/fr not_active IP Right Cessation
- 1982-08-23 CH CH5007/82A patent/CH655114A5/fr not_active IP Right Cessation
- 1982-08-23 HU HU822708A patent/HU186107B/hu unknown
- 1982-08-23 SE SE8204817A patent/SE448543B/sv not_active IP Right Cessation
- 1982-08-23 IT IT22938/82A patent/IT1152505B/it active Protection Beyond IP Right Term
- 1982-08-23 UA UA3482389A patent/UA5971A1/uk unknown
- 1982-08-23 DE DE19823231255 patent/DE3231255A1/de active Granted
- 1982-08-23 AU AU87493/82A patent/AU571430B2/en not_active Expired
- 1982-08-23 GB GB08224155A patent/GB2104522B/en not_active Expired
- 1982-08-23 LU LU84347A patent/LU84347A1/fr unknown
- 1982-08-23 ZA ZA826120A patent/ZA826120B/xx unknown
- 1982-08-23 DE DE1999175037 patent/DE19975037I2/de active Active
- 1982-08-23 ES ES515176A patent/ES515176A0/es active Granted
- 1982-08-23 NZ NZ201668A patent/NZ201668A/en unknown
- 1982-08-23 GR GR69093A patent/GR76863B/el unknown
- 1982-08-23 IE IE2026/82A patent/IE53408B1/en not_active IP Right Cessation
- 1982-08-23 FR FR8214461A patent/FR2511679A1/fr active Granted
- 1982-08-23 KR KR8203774A patent/KR890000094B1/ko not_active Expired
- 1982-08-23 JP JP57144902A patent/JPS5843975A/ja active Granted
- 1982-08-23 SU SU823482389A patent/SU1447284A3/ru active
- 1982-08-23 CA CA000409950A patent/CA1197247A/fr not_active Expired
- 1982-08-23 DK DK377882A patent/DK161147C/da not_active IP Right Cessation
- 1982-08-23 FI FI822921A patent/FI73434C/fi not_active IP Right Cessation
-
1993
- 1993-06-19 LV LV930621A patent/LV5511A3/xx unknown
- 1993-09-29 LT LTRP1286A patent/LT2436B/xx not_active IP Right Cessation
- 1993-11-16 GE GEAP19931653A patent/GEP19960641B/en unknown
- 1993-12-03 LV LV931303A patent/LV5621A3/xx unknown
-
1999
- 1999-04-01 NL NL990010C patent/NL990010I2/nl unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2932305A1 (de) * | 1979-08-09 | 1981-02-26 | Basf Ag | Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EIH | Change in the person of patent owner | ||
| EZF | Grant of a certificate of protection |
Free format text: SZ 26/1999, 19990618, EXPIRES:20080915 |
|
| SZA | Application filed for a certificate of protection |
Free format text: SZ 26/1999, 19990618 |
|
| ELA | Expired due to lapse of time |