AT361141B - Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren - Google Patents

Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren

Info

Publication number
AT361141B
AT361141B AT119477A AT119477A AT361141B AT 361141 B AT361141 B AT 361141B AT 119477 A AT119477 A AT 119477A AT 119477 A AT119477 A AT 119477A AT 361141 B AT361141 B AT 361141B
Authority
AT
Austria
Prior art keywords
androstadien
producing new
carbonic acids
new esters
esters
Prior art date
Application number
AT119477A
Other languages
English (en)
Other versions
ATA119477A (de
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AT355279A priority Critical patent/AT363207B/de
Priority to AT354979A priority patent/AT362888B/de
Priority to AT355179A priority patent/AT362889B/de
Priority to AT355079A priority patent/AT364098B/de
Publication of ATA119477A publication Critical patent/ATA119477A/de
Application granted granted Critical
Publication of AT361141B publication Critical patent/AT361141B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT119477A 1976-02-24 1977-02-23 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren AT361141B (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AT355279A AT363207B (de) 1976-02-24 1979-05-14 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren
AT354979A AT362888B (de) 1976-02-24 1979-05-14 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren
AT355179A AT362889B (de) 1976-02-24 1979-05-14 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren
AT355079A AT364098B (de) 1976-02-24 1979-05-14 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH225376A CH628355A5 (de) 1976-02-24 1976-02-24 Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.

Publications (2)

Publication Number Publication Date
ATA119477A ATA119477A (de) 1980-07-15
AT361141B true AT361141B (de) 1981-02-25

Family

ID=4229445

Family Applications (1)

Application Number Title Priority Date Filing Date
AT119477A AT361141B (de) 1976-02-24 1977-02-23 Verfahren zur herstellung von neuen estern von androstadien-17-carbonsaeuren

Country Status (26)

Country Link
US (1) US4285937A (de)
JP (1) JPS52102264A (de)
AT (1) AT361141B (de)
AU (1) AU513559B2 (de)
BE (1) BE851725A (de)
CA (1) CA1084483A (de)
CH (4) CH628355A5 (de)
CY (1) CY1198A (de)
DD (1) DD145918A5 (de)
DE (1) DE2707336A1 (de)
DK (1) DK153493C (de)
ES (5) ES456134A1 (de)
FR (2) FR2342302A1 (de)
GB (1) GB1578243A (de)
HK (1) HK57483A (de)
HU (1) HU176762B (de)
IE (1) IE45023B1 (de)
IL (2) IL51519A (de)
KE (1) KE3300A (de)
MX (1) MX9203366A (de)
MY (1) MY8500017A (de)
NL (1) NL7701886A (de)
NZ (1) NZ183418A (de)
SE (1) SE436572B (de)
SG (1) SG37383G (de)
ZA (1) ZA771087B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7967677A0 (it) * 1978-04-05 1979-03-30 Syntex Inc Erivati dell acido 4 alogeno etiani co ad azione antinfiammatoria e procedimento per la loro preparazione
US4198403A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE3024008C2 (de) * 1980-06-24 1982-04-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17α-Hydroxy-etiocarbonsäuren
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
WO1990015816A1 (en) * 1989-06-16 1990-12-27 The Upjohn Company Suramin type compounds and angiostatic steroids to inhibit angiogenesis
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5646136A (en) * 1994-01-04 1997-07-08 Duke University Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
GB0015876D0 (en) * 2000-06-28 2000-08-23 Novartis Ag Organic compounds
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
ES2292604T5 (es) * 2000-08-05 2015-06-01 Glaxo Group Limited Éster S-fluorometílico del ácido 6 ,9 -difluoro-17 -[(2-furanilcarbonil)oxi]-11 -hidroxi-16 -metil-3-oxo-androsta-1,4-dien-17 -carbotioico como agente antiinflamatorio
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
CN1302007C (zh) * 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
DE602004025002D1 (de) * 2003-06-19 2010-02-25 Nicholas S Bodor Steigerung der aktivität und/oder der wirkungsdauer weicher steroide mit anti-entzündungswirkung für topische oder lokale verabreichung
DE602004008083T2 (de) * 2003-06-19 2008-04-24 Nicholas S. Gainsville Bodor Verstärkung der aktivität und/oder wirkdauer von ausgewählten entzündungshemmenden steroiden
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
EP1948167A1 (de) * 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Zusammensetzungen von phosphodiesterase-typ-iv-hemmern
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EP2111861A1 (de) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Zusammensetzungen von Phosphodiesterase-IV-Hemmern
US8835410B2 (en) 2011-05-10 2014-09-16 Bodor Laboratories, Inc. Treatment of eyelid dermatitis
CN111100176A (zh) * 2019-12-20 2020-05-05 重庆华邦胜凯制药有限公司 一种化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636010A (en) * 1968-12-23 1972-01-18 Ciba Geigy Corp Esters of steroid-17-carboxylic acids
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) * 1974-08-30 1978-06-06 Glaxo Laboratories Limited Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates

Also Published As

Publication number Publication date
CY1198A (en) 1983-12-31
DK153493B (da) 1988-07-18
FR2369297B1 (de) 1981-03-06
DE2707336A1 (de) 1977-08-25
IL51519A0 (en) 1977-04-29
ZA771087B (en) 1978-01-25
NL7701886A (nl) 1977-08-26
SG37383G (en) 1984-02-17
IL61512A0 (en) 1980-12-31
GB1578243A (en) 1980-11-05
FR2342302B1 (de) 1981-01-09
CH628356A5 (de) 1982-02-26
AU2257277A (en) 1978-08-31
US4285937A (en) 1981-08-25
FR2342302A1 (fr) 1977-09-23
MY8500017A (en) 1985-12-31
IE45023L (en) 1977-08-24
ES467430A1 (es) 1979-08-16
JPS6139959B2 (de) 1986-09-06
BE851725A (fr) 1977-08-23
DE2707336C2 (de) 1988-09-01
CH629824A5 (de) 1982-05-14
ATA119477A (de) 1980-07-15
DD145918A5 (de) 1981-01-14
HU176762B (en) 1981-05-28
DK79077A (da) 1977-08-25
NZ183418A (en) 1980-02-21
CH628355A5 (de) 1982-02-26
IE45023B1 (en) 1982-06-02
FR2369297A1 (fr) 1978-05-26
CA1084483A (en) 1980-08-26
ES467434A1 (es) 1979-08-16
ES467432A1 (es) 1979-08-16
KE3300A (en) 1983-08-05
DK153493C (da) 1988-11-28
ES456134A1 (es) 1978-05-01
JPS52102264A (en) 1977-08-27
CH628641A5 (de) 1982-03-15
AU513559B2 (en) 1980-12-11
MX9203366A (es) 1992-09-01
IL51519A (en) 1983-03-31
SE7701999L (sv) 1977-08-25
HK57483A (en) 1983-11-25
ES467433A1 (es) 1979-10-16
SE436572B (sv) 1985-01-07

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time
REN Ceased due to non-payment of the annual fee