AR083448A1 - Polipeptidos con actividad quinasa - Google Patents

Polipeptidos con actividad quinasa

Info

Publication number
AR083448A1
AR083448A1 ARP110103811A ARP110103811A AR083448A1 AR 083448 A1 AR083448 A1 AR 083448A1 AR P110103811 A ARP110103811 A AR P110103811A AR P110103811 A ARP110103811 A AR P110103811A AR 083448 A1 AR083448 A1 AR 083448A1
Authority
AR
Argentina
Prior art keywords
polypeptides
kinase activity
polypeptide
seq
mutation
Prior art date
Application number
ARP110103811A
Other languages
English (en)
Inventor
Hendrik Wouter Wisselink
Maris Antonius Jeroen Adriaan Van
Jacobus Thomas Pronk
Paul Klaassen
Jong Rene Marcel De
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of AR083448A1 publication Critical patent/AR083448A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Polipéptidos que tienen una mutación en una o más posiciones correspondientes a Y274 y/o D376 de la SEQ ID Nº 51, en donde el polipéptido tiene al menos un 50% de identidad de secuencia con la SEQ ID Nº 51 y en donde el polipéptido tiene actividad galactoquinasa.
ARP110103811A 2010-10-13 2011-10-13 Polipeptidos con actividad quinasa AR083448A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39261710P 2010-10-13 2010-10-13
EP10075710 2010-10-13

Publications (1)

Publication Number Publication Date
AR083448A1 true AR083448A1 (es) 2013-02-27

Family

ID=43480439

Family Applications (3)

Application Number Title Priority Date Filing Date
ARP110103812A AR083449A1 (es) 2010-10-13 2011-10-13 Celula de levadura fermentadora de pentosas y glucosa
ARP110103810A AR083447A1 (es) 2010-10-13 2011-10-13 Polipeptidos con actividad permeasa
ARP110103811A AR083448A1 (es) 2010-10-13 2011-10-13 Polipeptidos con actividad quinasa

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ARP110103812A AR083449A1 (es) 2010-10-13 2011-10-13 Celula de levadura fermentadora de pentosas y glucosa
ARP110103810A AR083447A1 (es) 2010-10-13 2011-10-13 Polipeptidos con actividad permeasa

Country Status (16)

Country Link
US (2) US9353376B2 (es)
EP (2) EP2627767A1 (es)
JP (2) JP5961886B2 (es)
KR (2) KR20140005883A (es)
CN (2) CN103154234B (es)
AR (3) AR083449A1 (es)
AU (2) AU2011315572B2 (es)
BR (2) BR112013008981A2 (es)
CA (2) CA2813513A1 (es)
DK (1) DK2627765T3 (es)
EA (2) EA201300455A1 (es)
ES (1) ES2629252T3 (es)
MX (2) MX2013004121A (es)
MY (1) MY160995A (es)
PL (1) PL2627765T3 (es)
WO (3) WO2012049173A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011315572B2 (en) 2010-10-13 2015-09-03 Dsm Ip Assets B.V. Polypeptides with permease activity
US10189892B2 (en) 2013-03-15 2019-01-29 Alderbio Holdings Llc Fermentation process for antibody production
WO2014195379A1 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195380A1 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195378A1 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195381A2 (en) * 2013-06-05 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2014195521A2 (en) * 2013-12-18 2014-12-11 Dsm Ip Assets B.V. Polypeptides with permease activity
WO2015091757A1 (en) * 2013-12-19 2015-06-25 Dsm Ip Assets B.V. Polypeptides with permease activity
KR102277898B1 (ko) 2014-07-03 2021-07-15 삼성전자주식회사 산물 생산능이 향상된 효모 및 그를 이용한 산물을 생산하는 방법
HUE044424T2 (hu) 2014-10-22 2019-10-28 Butalco Gmbh A GAL2 transzporter változatai és azok alkalmazása
WO2017024150A1 (en) 2015-08-05 2017-02-09 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
WO2017067698A1 (en) 2015-10-22 2017-04-27 Direvo Industrial Biotechnology Gmbh Method for producing a fermentation product
DK3416740T3 (da) 2016-02-19 2021-02-08 Intercontinental Great Brands Llc Fremgangsmåder til dannelse af multiple værdistrømme ud fra biomassekilder
CN106222101B (zh) * 2016-07-27 2020-03-27 中国科学技术大学 高温下高效利用菊芋一步生产高纯果糖的耐高温菌株及应用
US11365417B2 (en) * 2017-09-12 2022-06-21 Bio Capital Holdings, LLC Biological devices and methods of use thereof to produce steviol glycosides
EP3710469B1 (en) * 2017-11-14 2021-12-08 DSM IP Assets B.V. Polypeptides with improved arabinose transport specificity
US11198847B2 (en) 2018-02-01 2021-12-14 Dsm Ip Assets B.V. Yeast cell capable of simultaneously fermenting hexose and pentose sugars
CN111304228B (zh) * 2020-03-18 2022-02-22 中国热带农业科学院橡胶研究所 一种橡胶树线粒体型己糖激酶基因及其编码蛋白和应用
WO2023000243A1 (zh) * 2021-07-22 2023-01-26 深圳先进技术研究院 重组酵母生物转化生产葡萄糖的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
CA2063592C (en) 1989-07-07 2003-01-21 Marco L. F. Giuseppin Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
FR2679920A1 (fr) 1991-08-02 1993-02-05 Rhone Poulenc Rorer Sa Levures recombinantes hautement stables pour la production de proteines recombinantes, leur preparation et leur utilisation.
ATE238425T1 (de) 1993-07-23 2003-05-15 Dsm Nv Selektionmarker-genfreie rekombinante stämme: verfahren zur ihrer herstellung und die verwendung dieser stämme
CN1169961C (zh) 1997-04-11 2004-10-06 Dsm公司 基因转变作为工具用于构建重组的工业化丝状真菌
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
AU4144999A (en) 1998-05-19 1999-12-06 Dsm N.V. Improved (in vivo) production of cephalosporins
KR20010089672A (ko) 1998-12-22 2001-10-08 윌리암 로엘프 드 보에르 개선된 생체내 세팔로스포린 생산
JP4334352B2 (ja) * 2002-01-23 2009-09-30 ロイヤル ネダルコ ベスローテン フェンノートシャップ ペントース糖の発酵
SE0202090D0 (sv) 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modifierd yeast consuming L-arabinose
EP1513940A4 (en) 2002-05-30 2006-10-25 Cargill Dow Llc METHOD AND MATERIALS FOR THE PRODUCTION OF MILKY ACID IN YEAST
WO2004085627A1 (en) 2003-03-26 2004-10-07 Forskarpatent I Syd Ab New saccharomyces cerevisiae strains utilizing xylose
WO2005056786A2 (en) * 2003-12-05 2005-06-23 Wisconsin Alumni Research Foundation Sugar kinases with expanded substrate specificity and their use
CN101052706B (zh) 2004-07-16 2015-02-18 帝斯曼知识产权资产管理有限公司 发酵木糖的真核细胞的代谢工程
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
CA2664646C (en) 2006-10-02 2016-09-20 Dsm Ip Assets B.V. Metabolic engineering of arabinose- fermenting yeast cells
WO2008086124A1 (en) 2007-01-03 2008-07-17 Vialogy Llc Multi parallax exploitation for omni-directional imaging electronic eye
WO2008121701A1 (en) 2007-03-30 2008-10-09 Cargill Inc. Metabolic engineering of yeasts for the production of 1-butanol
DK2145008T3 (en) * 2007-04-09 2016-06-20 Univ Georgia SUBSTRATSELEKTIV CO-fermentation process
US20100304454A1 (en) 2007-07-19 2010-12-02 Royal Nedalco B.V. Novel arabinose-fermenting eukaryotic cells
ES2407639T3 (es) 2008-02-04 2013-06-13 Toray Industries, Inc. Procedimiento de producción de ácido láctico por fermentación continua
BRPI0908932A2 (pt) 2008-03-13 2018-02-14 Dsm Ip Assets Bv seleção de organismos capazes de fermentar substratos mistos
DE102008029302B4 (de) 2008-06-19 2016-08-11 Insilico Biotechnology Ag Biotechnologische Herstellung von Acrylsäure
FR2934264B1 (fr) 2008-07-22 2012-07-20 Arkema France Fabrication d'esters de vinyle a partir de matieres renouvelables, esters de vinyle obtenus et utilisations
JP5821132B2 (ja) * 2008-12-24 2015-11-24 ディーエスエム アイピー アセッツ ビー．ブイ． キシロース異性化酵素遺伝子及びペントース糖の発酵におけるそれらの使用
CA2753538A1 (en) 2009-02-25 2010-09-02 Indiana University Research & Technology Corporation Materials and methods for identifying and using yeast strains that metabolize pentose sugars in the presence of d-glucose
KR20110122134A (ko) * 2009-02-25 2011-11-09 머크 샤프 앤드 돔 코포레이션 글리코공학처리된 효모 피키아 파스토리스에서 갈락토스 동화 경로의 대사 공학
AU2011315572B2 (en) 2010-10-13 2015-09-03 Dsm Ip Assets B.V. Polypeptides with permease activity

Also Published As

Publication number Publication date
CA2813513A1 (en) 2012-04-19
AU2011315572A1 (en) 2013-04-11
AU2011315569B2 (en) 2015-09-24
WO2012049173A1 (en) 2012-04-19
MX2013004121A (es) 2014-02-27
KR20130100169A (ko) 2013-09-09
MY160995A (en) 2017-03-28
ES2629252T3 (es) 2017-08-08
US9034608B2 (en) 2015-05-19
EP2627765A2 (en) 2013-08-21
EA201300454A1 (ru) 2013-09-30
DK2627765T3 (en) 2017-08-28
AR083449A1 (es) 2013-02-27
PL2627765T3 (pl) 2017-10-31
AU2011315569A1 (en) 2013-04-11
MX2013004127A (es) 2013-05-20
WO2012049170A2 (en) 2012-04-19
AU2011315572B2 (en) 2015-09-03
WO2012049179A2 (en) 2012-04-19
CA2813531A1 (en) 2012-04-19
US9353376B2 (en) 2016-05-31
US20130273601A1 (en) 2013-10-17
AU2011315569C1 (en) 2016-02-04
BR112013009157A2 (pt) 2016-07-26
JP5961886B2 (ja) 2016-08-03
US20130236932A1 (en) 2013-09-12
EA201300455A1 (ru) 2013-09-30
KR20140005883A (ko) 2014-01-15
CN103154234A (zh) 2013-06-12
AR083447A1 (es) 2013-02-27
CN103189505A (zh) 2013-07-03
JP2013542724A (ja) 2013-11-28
EP2627767A1 (en) 2013-08-21
CN103154234B (zh) 2016-08-17
WO2012049179A3 (en) 2012-06-14
WO2012049170A3 (en) 2012-06-14
EP2627765B1 (en) 2017-05-10
BR112013008981A2 (pt) 2017-10-03
JP2013539655A (ja) 2013-10-28

Similar Documents

Publication Publication Date Title
AR083448A1 (es) Polipeptidos con actividad quinasa
ES2545895T3 (es) Proteína de fusión anticancerígena
UA116980C2 (uk) Полінуклеотид, який кодує 5-енолпірувілшикімат-3-фосфатсинтазу, та його використання в наданні рослині стійкості до гліфосату
ES2691070T3 (es) Péptidos antiinflamatorios y composición que comprende los mismos
TN2017000085A1 (en) Polypeptide having a polyester degrading activity and uses thereof
NZ707439A (en) Modified factor ix polypeptides and uses thereof
BRPI0910461A2 (pt) fsh recombinante incluindo sialilação alfa 2,3 e alfa 2,6
UA108646C2 (xx) Клостридіальні токсини, що руйнуються
ES2531290T3 (es) Transferasas y oxidorreductasas, ácidos nucleicos que las codifican y métodos para prepararlas y usarlas
BRPI0919696A2 (pt) Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.
WO2014008480A3 (en) Cell line expressing single chain factor viii polypeptides and uses thereof
AR066410A1 (es) Nuevas asparraginasas y sus usos
ES2694667T3 (es) Método para producir oxalato oxidasas que tienen actividad óptica cerca de pH fisiológico y uso de tales oxalato oxidasas recombinantes en el tratamiento de enfermedades relacionadas con oxalato
MX2016009651A (es) Proteina.
AU2018253611A1 (en) Engineered pesticidal proteins
AR102410A1 (es) Polipéptidos que tienen actividad xilanasa con una tasa de conversión alta de polisacáridos que contienen xilosa
AR102919A1 (es) Variantes de lipasa y polinucleótidos que las codifican
MX2015005271A (es) Polinucleotidos, polipeptidos y metodos de suso novedoso de aciltransferasa.
AR093025A1 (es) Celulas con conversion mejorada de pentosas
MY153917A (en) Tsp-1, tsp-2, il-17br and hb-egf associated with stem cell activities and applications thereof
SG10201803999UA (en) Recombinant factor viii formulations
UY31675A (es) Combinacion de genes de marcadores para caracterizar una cepa de lactobacillus sakei
AR095027A1 (es) VARIANTES DE a-AMILASA
ES2669528T3 (es) Receptor Tie2 específico de angiopoyetina-2
ES2647576T3 (es) Prueba genética para la predisposición genética a la hemofilia A en bichones habaneros

Legal Events

Date Code Title Description
FB Suspension of granting procedure