MX2016009651A - Proteina. - Google Patents
Proteina.Info
- Publication number
- MX2016009651A MX2016009651A MX2016009651A MX2016009651A MX2016009651A MX 2016009651 A MX2016009651 A MX 2016009651A MX 2016009651 A MX2016009651 A MX 2016009651A MX 2016009651 A MX2016009651 A MX 2016009651A MX 2016009651 A MX2016009651 A MX 2016009651A
- Authority
- MX
- Mexico
- Prior art keywords
- xylanase
- modified
- parent
- fragment
- enzyme
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
- A23K10/38—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material from distillers' or brewers' waste
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
- C12C11/00—Fermentation processes for beer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
- C12C5/00—Other raw materials for the preparation of beer
- C12C5/004—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
- C12C7/00—Preparation of wort
- C12C7/04—Preparation or treatment of the mash
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2477—Hemicellulases not provided in a preceding group
- C12N9/248—Xylanases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2477—Hemicellulases not provided in a preceding group
- C12N9/248—Xylanases
- C12N9/2482—Endo-1,4-beta-xylanase (3.2.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2477—Hemicellulases not provided in a preceding group
- C12N9/248—Xylanases
- C12N9/2485—Xylan endo-1,3-beta-xylosidase (3.2.1.32), i.e. endo-1,3-beta-xylanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01008—Endo-1,4-beta-xylanase (3.2.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01032—Xylan endo-1,3-beta-xylosidase (3.2.1.32), i.e. endo-1-3-beta-xylanase
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Animal Husbandry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Abstract
La presente invención se refiere a una enzima xilanasa GH10 modificada o un fragmento de esta que tiene actividad xilanasa, en donde esa xilanasa GH10 modificada o el fragmento de esta tiene una mayor termoestabilidad en comparación con una enzima xilanasa GH10 parental; la xilanasa GH10 parental se modificó en al menos dos posiciones siguientes 7, 33, 79, 217 y 298, en donde la numeración está basada en la numeración de aminoácidos de FveXyn4 (sec. con núm. de ident. 1). Particularmente, la enzima xilanasa modificada de conformidad con la presente invención tiene las modificaciones siguientes: N7D; T33V; K79Y, V, F, I, L o M (preferentemente, K79Y, F o V, con mayor preferencia, Y); A217Q, E, P, D o M (preferentemente, A217Q, E o P, con mayor preferencia, Q); y T298Y, F o W (preferentemente, Y o F, con mayor preferencia, Y).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201401648A GB201401648D0 (en) | 2014-01-31 | 2014-01-31 | Protein |
PCT/EP2015/051982 WO2015114112A1 (en) | 2014-01-31 | 2015-01-30 | Protein |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016009651A true MX2016009651A (es) | 2016-11-28 |
Family
ID=50344157
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016009651A MX2016009651A (es) | 2014-01-31 | 2015-01-30 | Proteina. |
MX2020011083A MX2020011083A (es) | 2014-01-31 | 2016-07-25 | Proteina. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020011083A MX2020011083A (es) | 2014-01-31 | 2016-07-25 | Proteina. |
Country Status (16)
Country | Link |
---|---|
US (1) | US10165787B2 (es) |
EP (2) | EP3099791B1 (es) |
JP (1) | JP6522010B2 (es) |
KR (2) | KR102295417B1 (es) |
CN (2) | CN113355307A (es) |
AR (1) | AR101147A1 (es) |
AU (2) | AU2015212749B2 (es) |
BR (1) | BR112016017534A2 (es) |
CA (1) | CA2937043C (es) |
DK (1) | DK3099791T3 (es) |
ES (1) | ES2811767T3 (es) |
GB (1) | GB201401648D0 (es) |
HU (1) | HUE050893T2 (es) |
MX (2) | MX2016009651A (es) |
PL (1) | PL3099791T3 (es) |
WO (1) | WO2015114112A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11981942B2 (en) | 2013-07-23 | 2024-05-14 | International N&H Denmark Aps | Xylanases for solubilizing arabinoxylan-containing material |
WO2015116395A1 (en) * | 2014-01-31 | 2015-08-06 | Danisco Us Inc. | Methods for improving by-products from fermentation processes using xylanase |
CA3006992A1 (en) | 2015-12-22 | 2017-06-29 | Novozymes A/S | Processes for improving fermentation product yield using phospholipase c |
BR112020012058B1 (pt) * | 2017-12-20 | 2024-01-02 | Dsm Ip Assets B.V. | Composições de ração animal e usos das mesmas |
BR112020018294A2 (pt) * | 2018-03-09 | 2020-12-29 | Danisco Us Inc. | Glucoamilases e métodos de uso dos mesmos |
EP3818154A1 (en) | 2018-07-06 | 2021-05-12 | DuPont Nutrition Biosciences ApS | Xylanase-containing feed additives for cereal-based animal feed |
CL2018003617A1 (es) | 2018-12-14 | 2019-03-22 | Univ Santiago Chile | Polipéptido con actividad xilanasa, secuencia nucleotídica que lo codifica, ingrediente y proceso que comprende dicho ingrediente para la preparación de un producto alimenticio |
US11440269B2 (en) * | 2020-03-14 | 2022-09-13 | Kurtis Zhang | Process of making a gluten-based biodegradable material |
KR20230167903A (ko) * | 2022-06-03 | 2023-12-12 | 씨제이제일제당 (주) | 자일라나제 활성을 갖는 변이형 폴리펩티드 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
EP0531372B2 (en) | 1990-05-09 | 2004-04-14 | Novozymes A/S | A cellulase preparation comprising an endoglucanase enzyme |
DK13491D0 (da) | 1991-01-25 | 1991-01-25 | Novo Nordisk As | Anvendelse af et enzymholdigt granulat og fremgangsmaade til fremstilling af et forderstof i tabletform |
ATE222956T1 (de) * | 1994-06-14 | 2002-09-15 | Genencor Int | Hitzebeständige xylanasen |
JPH11514240A (ja) | 1995-11-02 | 1999-12-07 | ノボ ノルディスク アクティーゼルスカブ | 飼料酵素調製品 |
FI108728B (fi) * | 1999-10-12 | 2002-03-15 | Carbozyme Oy | Menetelmä perheen G/11 ksylanaasien stabiilisuuden parantamiseksi ja optimaalisen pH-alueen muuttamiseksi |
CZ2003798A3 (cs) | 2000-09-21 | 2003-08-13 | Dsm N. V. | Polypeptid s aktivitou xylanázy, sekvence nukleové kyseliny kódující polypeptid, způsob přípravy a použití polypeptidu |
AU2002210409A1 (en) * | 2000-11-10 | 2002-05-21 | Novozymes A/S | Ethanol process |
US7510860B1 (en) * | 2001-11-21 | 2009-03-31 | National Research Council Of Canada | Xylanases with enhanced thermophilicity and alkalophilicity |
ES2381207T3 (es) | 2003-05-29 | 2012-05-24 | Danisco Us Inc. | Nuevos genes de trichoderma |
ES2443019T1 (es) * | 2005-10-12 | 2014-02-17 | Danisco Us Inc. | Gránulos estables y duraderos con agentes activos |
GB0612976D0 (en) * | 2006-06-30 | 2006-08-09 | Leuven K U Res & Dev | Method for making arabinoxylo-oligosaccharides as a co-product of fermentation of whole grain cereals |
NZ584967A (en) | 2007-10-03 | 2012-08-31 | Verenium Corp | Xylanases, nucleic acids encoding them and methods for making and using them |
JP5435812B2 (ja) | 2008-03-07 | 2014-03-05 | ダニスコ・ユーエス・インク | トリコデルマ中でのカタラーゼの発現 |
AU2010329917B2 (en) * | 2009-12-09 | 2014-12-04 | Novozymes A/S | Methods of producing GH8 xylanase variants |
WO2015116395A1 (en) * | 2014-01-31 | 2015-08-06 | Danisco Us Inc. | Methods for improving by-products from fermentation processes using xylanase |
-
2014
- 2014-01-31 GB GB201401648A patent/GB201401648D0/en not_active Ceased
-
2015
- 2015-01-30 DK DK15702249.2T patent/DK3099791T3/da active
- 2015-01-30 WO PCT/EP2015/051982 patent/WO2015114112A1/en active Application Filing
- 2015-01-30 AR ARP150100278A patent/AR101147A1/es active IP Right Grant
- 2015-01-30 CA CA2937043A patent/CA2937043C/en active Active
- 2015-01-30 JP JP2016567156A patent/JP6522010B2/ja active Active
- 2015-01-30 KR KR1020167020745A patent/KR102295417B1/ko active IP Right Grant
- 2015-01-30 ES ES15702249T patent/ES2811767T3/es active Active
- 2015-01-30 AU AU2015212749A patent/AU2015212749B2/en active Active
- 2015-01-30 HU HUE15702249A patent/HUE050893T2/hu unknown
- 2015-01-30 PL PL15702249T patent/PL3099791T3/pl unknown
- 2015-01-30 KR KR1020217023230A patent/KR102508272B1/ko active IP Right Grant
- 2015-01-30 CN CN202110631154.0A patent/CN113355307A/zh active Pending
- 2015-01-30 EP EP15702249.2A patent/EP3099791B1/en active Active
- 2015-01-30 CN CN201580006245.8A patent/CN105992819B/zh active Active
- 2015-01-30 BR BR112016017534A patent/BR112016017534A2/pt not_active Application Discontinuation
- 2015-01-30 EP EP20165858.0A patent/EP3702450B1/en active Active
- 2015-01-30 MX MX2016009651A patent/MX2016009651A/es unknown
- 2015-01-30 US US15/114,914 patent/US10165787B2/en active Active
-
2016
- 2016-07-25 MX MX2020011083A patent/MX2020011083A/es unknown
-
2020
- 2020-05-19 AU AU2020203266A patent/AU2020203266B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3099791A1 (en) | 2016-12-07 |
EP3099791B1 (en) | 2020-05-20 |
DK3099791T3 (da) | 2020-08-24 |
AU2020203266B2 (en) | 2022-09-15 |
CA2937043A1 (en) | 2015-08-06 |
CN105992819B (zh) | 2021-07-13 |
JP2017505636A (ja) | 2017-02-23 |
PL3099791T3 (pl) | 2020-11-16 |
AU2015212749B2 (en) | 2020-05-21 |
CN105992819A (zh) | 2016-10-05 |
KR20160137955A (ko) | 2016-12-02 |
EP3702450A1 (en) | 2020-09-02 |
ES2811767T3 (es) | 2021-03-15 |
HUE050893T2 (hu) | 2021-01-28 |
CA2937043C (en) | 2023-10-24 |
WO2015114112A1 (en) | 2015-08-06 |
US10165787B2 (en) | 2019-01-01 |
WO2015114112A8 (en) | 2016-08-11 |
KR20210094676A (ko) | 2021-07-29 |
JP6522010B2 (ja) | 2019-05-29 |
AR101147A1 (es) | 2016-11-30 |
US20160345609A1 (en) | 2016-12-01 |
KR102508272B1 (ko) | 2023-03-08 |
AU2015212749A1 (en) | 2016-07-07 |
EP3702450B1 (en) | 2024-04-10 |
MX2020011083A (es) | 2020-11-06 |
AU2015212749A8 (en) | 2016-08-25 |
BR112016017534A2 (pt) | 2017-12-12 |
CN113355307A (zh) | 2021-09-07 |
GB201401648D0 (en) | 2014-03-19 |
AU2020203266A1 (en) | 2020-06-11 |
KR102295417B1 (ko) | 2021-08-31 |
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