AR066410A1 - Nuevas asparraginasas y sus usos - Google Patents

Nuevas asparraginasas y sus usos

Info

Publication number
AR066410A1
AR066410A1 ARP080101640A ARP080101640A AR066410A1 AR 066410 A1 AR066410 A1 AR 066410A1 AR P080101640 A ARP080101640 A AR P080101640A AR P080101640 A ARP080101640 A AR P080101640A AR 066410 A1 AR066410 A1 AR 066410A1
Authority
AR
Argentina
Prior art keywords
asparaginase
new
asparraginases
seq
variants
Prior art date
Application number
ARP080101640A
Other languages
English (en)
Inventor
Der Laan Jan Metske Van
Mark Cristiaan Stor
Lange Ilse De
Lisette Mohrmann
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Publication of AR066410A1 publication Critical patent/AR066410A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01001—Asparaginase (3.5.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Asparraginasa que tiene una amplitud de perfil de pH para la actividad de al menos 3.5. Además, la presente se relaciona con polipéptidos de asparraginasa identificados recientemente de acuerdo con cualquiera de SEQ ID N°: 2 o SEQ ID N°:4, con variantes de éstos, y con secuencias de polinucleotidos que codifican estas nuevas variantes de asparraginasa. Además, la presente se relaciona con el uso de estas nuevas variantes de asparraginasa en procesos industriales, del campo de la alimentacion y farmacéutico.
ARP080101640A 2007-04-20 2008-04-18 Nuevas asparraginasas y sus usos AR066410A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07106660 2007-04-20
EP07106664 2007-04-20
EP07106662 2007-04-20

Publications (1)

Publication Number Publication Date
AR066410A1 true AR066410A1 (es) 2009-08-19

Family

ID=39650693

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101640A AR066410A1 (es) 2007-04-20 2008-04-18 Nuevas asparraginasas y sus usos

Country Status (14)

Country Link
US (3) US20100136169A1 (es)
EP (1) EP2137306B1 (es)
JP (1) JP2010524448A (es)
AR (1) AR066410A1 (es)
AU (1) AU2008240797A1 (es)
BR (1) BRPI0810481B1 (es)
CA (1) CA2682677A1 (es)
CL (2) CL2008001129A1 (es)
DK (1) DK2137306T3 (es)
EA (1) EA017305B1 (es)
ES (1) ES2550362T3 (es)
IL (1) IL201018A0 (es)
MX (1) MX2009011256A (es)
WO (1) WO2008128975A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730832B1 (en) 2001-09-10 2004-05-04 Luis Mayan Dominguez High threonine producing lines of Nicotiana tobacum and methods for producing
EP2851424B1 (en) 2007-03-09 2016-09-21 Novozymes A/S Thermostable asparaginases
CA2683078C (en) 2007-04-20 2016-03-29 Dsm Ip Assets B.V. Asparaginase enzyme variants and uses thereof
US20110129569A1 (en) 2009-11-26 2011-06-02 Dsm Ip Assets B.V. Method to produce fried vegetable products
CN102869772A (zh) * 2010-04-27 2013-01-09 帝斯曼知识产权资产管理有限公司 新颖的天冬酰胺酶
WO2012007192A1 (en) * 2010-07-14 2012-01-19 Nestec S.A. Asparaginase from basidiomycetes
CA2817224A1 (en) 2010-11-19 2012-05-24 Novozymes North America, Inc. Processes of producing a fermentation product
WO2012158320A1 (en) 2011-05-13 2012-11-22 Baker Hughes Incorporated Method of using asparaginase as a polyacrylamide enzyme breaker
US8716571B2 (en) 2011-09-21 2014-05-06 Reynolds Technologies, Inc. Tobacco having reduced amounts of amino acids and methods for producing such lines
BR112014006735B1 (pt) * 2011-09-21 2021-06-22 Reynolds Technologies, Inc Método de produção de uma planta de tabaco modificada e produto de tabaco
US9137958B2 (en) 2012-02-08 2015-09-22 Reynolds Technologies, Inc. Tobacco having altered amounts of environmental contaminants
CA2881952C (en) * 2012-08-17 2021-02-16 Novozymes A/S Method for producing a food product
BR112015003257A2 (pt) 2012-08-17 2017-11-14 Novozymes As variante de asparaginase, métodos para produção de um produto alimentar a partir de um material alimentar, para produção de uma variante de asparaginase e para obtenção de uma variante de asparaginase, polinucleotídeo isolado, constructo de ácido nucleico, vetor de expressão, e, célula hospedeira
KR20220002721A (ko) 2013-11-21 2022-01-06 엔테그리스, 아이엔씨. 플라즈마 시스템에서 사용되는 챔버 구성요소를 위한 표면 코팅
EP3197291A1 (en) 2014-07-04 2017-08-02 West Systems S.r.l Method and composition to reduce the formation of acrylamide in fresh or pre-fried foods to be subjected to heat treatment
RU2764014C2 (ru) * 2015-07-07 2022-01-12 Ренессанс Байосайенс Корп. Создание уменьшающих уровень аспарагина дрожжей путем адаптивной эволюции и их применение для уменьшения образования акриламида
AU2018354067B2 (en) 2017-10-27 2023-03-30 Pfenex Inc. Method for production of recombinant Erwinia asparaginase
US20210299233A1 (en) 2018-07-12 2021-09-30 The Children's Medical Center Corporation Method for treating cancer
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3819540B2 (ja) * 1996-06-07 2006-09-13 株式会社林原生物化学研究所 Ｌ−アスパラギナーゼ活性を有する哺乳類由来のポリペプチド
US7037540B2 (en) 2002-09-19 2006-05-02 Frito-Lay North America, Inc. Method for reducing acrylamide formation in thermally processed foods
US7524519B2 (en) 2002-09-20 2009-04-28 The Procter & Gamble Company Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce
DK1553848T3 (da) 2002-10-11 2008-01-21 Novozymes As Fremgangsmåde til fremstilling af et varmebehandlet produkt
US20040101607A1 (en) 2002-11-22 2004-05-27 The Procter & Gamble Company Method for reducing acrylamide in foods, foods having reduced levels of acrylamide, and article of commerce
CN100569101C (zh) * 2002-12-19 2009-12-16 帝斯曼知识产权资产管理有限公司 新颖的食物制造方法

Also Published As

Publication number Publication date
EP2137306A1 (en) 2009-12-30
ES2550362T3 (es) 2015-11-06
US20120045549A1 (en) 2012-02-23
CA2682677A1 (en) 2008-10-30
MX2009011256A (es) 2009-11-05
CL2008001129A1 (es) 2008-06-13
BRPI0810481B1 (pt) 2022-05-17
US20100136169A1 (en) 2010-06-03
EA200901432A1 (ru) 2010-04-30
BRPI0810481A2 (pt) 2014-10-07
JP2010524448A (ja) 2010-07-22
IL201018A0 (en) 2011-08-01
EA017305B1 (ru) 2012-11-30
US8323948B2 (en) 2012-12-04
DK2137306T3 (en) 2015-10-26
US20130023029A1 (en) 2013-01-24
AU2008240797A1 (en) 2008-10-30
WO2008128975A1 (en) 2008-10-30
EP2137306B1 (en) 2015-07-29
CL2008001128A1 (es) 2008-06-13

Similar Documents

Publication Publication Date Title
AR066410A1 (es) Nuevas asparraginasas y sus usos
EA200901430A1 (ru) Варианты фермента аспарагиназы и их применение
CL2012001405A1 (es) Compuestos derivados de espiroindolinona-pirrolidinas; proceso de obtención; composicion farmaceutica; y uso en el tratamiento o profilaxis del cancer.
GT201400033A (es) Pirimidinas anilladas sustituidas y uso de las mismas
UY32607A (es) Mutantes de fgf21 y usos del mismo
CR20110526A (es) Anticuerpos anti - tnf - alfa y sus usos
GT201300131A (es) Metodos de tratamiento de trastornos asociados con el fgf21
UA117218C2 (uk) Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
BR112017014060A2 (pt) composições de bacillus licheniformis rti184 e métodos de uso para beneficiar o crescimento de plantas
CL2012003026A1 (es) Composicion farmaceutica que comprende pioglitazona y linagliptina; procedimiento de preparacion; uso en el tratamiento de la diabetes tipo 2 o la obesidad.
CO6470854A2 (es) Variantes de celulasa con expresión, actividad y/o estabilidad mejoradas, y uso de las mismas
CL2013003372A1 (es) Compuestos derivados de espiro-[1,3]-oxacinas y espiro-[1,4]-oxacepinas, inhibidores de bace1 y/o bace2; composicion farmaceutica; procedimiento para prepararlos; y su uso en el tratamiento y/o la profilaxis de la enfermedad de alzheimer y diabetes.
CL2013002125A1 (es) Compuestos derivados de imidazo[5,1-f][1,2,4]triazinas; composicion farmaceutica; y uso en el tratamiento del deterioro cognitivo asociado con esquizofrenia.
CL2007001488A1 (es) Anticuerpo humano o humanizado anti-integrina alfa5beta1; acido nucleico que lo codifica; vector y celula huesped que lo comprenden; procedimiento de produccion; composicion farmaceutica que lo comprende; y su uso para prevenir o tratar trastornos asociados con la integrina.
AR083448A1 (es) Polipeptidos con actividad quinasa
CR20150196A (es) Moléculas de unión il-17a novedosas y usos médicos de las mismas
CO6680702A2 (es) Péptido o complejo péptido que se une a integrina alfa 2 y metodos y sus usos que implican a los mismos
BR112014024220A2 (pt) genes que codificam celulase
EA201990298A1 (ru) Способы и композиции для лечения рака
BR112013029256A2 (pt) "combinações farmacêuticas para uso no tratamento de pacientes com diabetes tipo 2, método de tratamento, e usos de lixisenatida e metformina".
CL2012003322A1 (es) Compuestos derivados de benzamida sustituidas; composicion farmacéutica; y uso en el tratamiento del cancer.
AR102950A1 (es) Variantes de lipasa y polinucleótidos que las codifican
CL2011000678A1 (es) Uso de una composicion combinada de ibuprofeno y paracetamol para preparar un medicamento para el tratamiento de osteoartritis o artritis reumatoidea.
ES2663096T3 (es) Métodos para el tratamiento del síndrome nefrótico y de afecciones relacionadas
BR112014001844A2 (pt) gene induzindo o alongamento de raízes ou aumentando a biomassa, e uso do mesmo

Legal Events

Date Code Title Description
FB Suspension of granting procedure